EP1328248A1 - Composition parfumante sans alcool - Google Patents
Composition parfumante sans alcoolInfo
- Publication number
- EP1328248A1 EP1328248A1 EP01974619A EP01974619A EP1328248A1 EP 1328248 A1 EP1328248 A1 EP 1328248A1 EP 01974619 A EP01974619 A EP 01974619A EP 01974619 A EP01974619 A EP 01974619A EP 1328248 A1 EP1328248 A1 EP 1328248A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition according
- perfuming
- emulsion
- perfume
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
Definitions
- the present invention relates to the field of perfumery. It relates more particularly to a concentrated perfume composition without alcohol, in the form of a translucent oil-in-water emulsion. Said perfuming composition can be used in particular in the form of a perfumed emulsion capable of being vaporized on the skin or the hair, on any other type of surface or even simply in ambient air.
- Oil-in-water emulsions are well known in the field of cosmetics and dermatology, in particular for the preparation of cosmetic products such as creams, lotions, tonics or serums.
- Such emulsions are for example described in European patent EP 728 460 which relates more particularly to transparent nanoemulsions based on fluid nonionic amphiphilic lipids and their use in cosmetics and dermopharmacy.
- These emulsions always contain a small proportion of a low molecular weight alcohol.
- the problems linked to the formulation of emulsions in the cosmetic field are not the same as in perfumery.
- the products for the care or hygiene of the body or of the hair are for example intended to optimize the penetration of active products into the surface layers of the skin.
- these cosmetic emulsions have a very particular composition and are characterized in particular by the fact that their oily phase comprises a wide variety of active products such as natural or synthetic oils, hydrocarbons, halogenated carbides, esters of mineral acid. , silicones, which differ depending on the desired application.
- a perfume composition constitutes a vector of perfume whose primary function is to impart an odor to a product.
- its oily phase consists essentially of perfuming ingredients.
- an emulsion in addition to chemical stability, must also meet certain requirements in terms of physical stability.
- one of the phenomena typically associated with the physical instability of an emulsion is the upward and downward movement of the dispersed drops with respect to the continuous phase, respectively called creaming or sedimentation.
- Microemulsions are dispersed systems which provide a solution to the problems of destabilization leading to the phase shift of a conventional emulsion. These systems are widely described in the prior art, for example in patent applications or patents such as EP 516 508, EP 572 080, US 5,320,863, US 5,585,343 or also FR 2,703,926. These documents all describe homogeneous, transparent and stable water and oil dispersions, these properties coming from the large quantities of surfactants and co-surfactants which are added thereto. Microemulsions and emulsions constitute two dispersed systems of a very distinct nature.
- microemulsions are unstable systems, the microemulsions are stable and form spontaneously when oil, water, surfactants and co-surfactants are mixed together.
- the thermodynamic stability of a microemulsion is reflected in particular by the fact that the average size of the drops of the system does not vary over time, unlike the case of an emulsion.
- the two dispersed systems are further distinguished by their optical properties. Indeed, microemulsions have an average drop size much smaller than the wavelength of light and a relatively narrow drop size distribution. Thus, this type of formulation diffuses little light and is therefore transparent, while the emulsions have a comparable drop size or greater than the wavelength of visible light and a wider drop size distribution as well.
- the object of the present invention is in particular to produce compositions which do not incorporate large quantities of surfactants relative to the quantity of perfuming ingredients, the presence of surfactants considerably limiting the proportion of perfume which can be added to the mixture.
- a dispersed system of microemulsion type is not suitable for the present invention, which therefore relates to a product in the form of an oil-in-water emulsion and which, despite its nature, exhibits physical stability quite surprisingly.
- Patent application JP 96225429 discloses so-called "alcohol-free" perfume compositions which generally contain a small proportion of alcohol.
- This application describes liquid perfume compositions or in the form of gels, comprising in particular water-soluble polymers such as gums. This type of polymer, well known in the field of emulsions, is used as a stabilizing agent.
- the present invention proposes to solve the problem of obtaining a product whose function is perfuming, in the form of a translucent emulsion without alcohol, capable of being vaporized, capable of containing a high percentage of perfume, appearance and pleasant touch, all combined with good long-term stability.
- the present invention provides a solution to the various problems mentioned, by means of an alcohol-free perfume composition in the form of a translucent oil-in-water vaporizable emulsion containing at least one perfume ingredient, a surfactant system having a hydrophilic balance. -lipophilic (HLB) greater than or equal to 10, and water.
- -lipophilic HLB
- the term “perfume composition” is understood here to mean a composition the primary function of which is to modify the odor of a product or impart an odor to a product or a person.
- the composition of the invention has been optimized so as to be able to comprise significant amounts of perfume, namely from 0.1 to 18% by weight, relative to the total weight of the emulsion.
- the emulsion is also characterized by the variation in the average size of its drops during the first month following its formulation, this variation being comprised, at a temperature of 45 ° C., between 0.1 and 30 nm.
- the emulsion which is the subject of the present invention has numerous advantages for the use which it is desired to make of it.
- this composition intended in particular to be sprayed on the skin or on the hair, on any other type of surface intended to be perfumed, or even in ambient air, is particularly concentrated in fragrance ingredients.
- the average size of the drops is such that the emulsion advantageously satisfies the desired stability criteria (absence of creaming or sedimentation effect) without, however, requiring the presence of stabilizing agents such as polymers soluble in water, as is the case in the prior art.
- the absence of such components has the advantage of obtaining a product of low viscosity, capable of being vaporized, non-sticky to the touch.
- the viscosity of the compositions according to the invention is less than 1 Pa.s.
- the average size of the emulsion drops has an optical effect on the final product, the translucent appearance of which with bluish reflections is highly appreciated by the consumer and is particularly suitable for use for derived products.
- a perfume such as perfume emulsions capable of being vaporized.
- the optical properties of the compositions of the invention are characterized by a transmission, measured at a wavelength of 600 nm, at 25 ° C, in a tank 1 cm thick, varying between 10 and 90%.
- the dispersed phase of the emulsion, object of the present invention consists essentially of perfuming ingredients. More particularly, it comprises from 50 to 99% of its weight of perfuming ingredients.
- the latter are present in an amount varying between 0.1 and 18% by weight relative to the total weight of the emulsion. Preferably, they constitute between 1 and 15% by weight relative to the total weight of the emulsion, or even between 6 and 10% by weight relative to the total weight of the emulsion.
- the perfuming ingredients which can be used according to the invention are ingredients of current use in perfumery. Their nature does not call for a more detailed description here, which cannot, moreover, be exhaustive, the skilled person being able to choose them on the basis of his general knowledge and according to the desired olfactory effect.
- These fragrance ingredients belong to chemical classes as varied as alcohols, aldehydes, ketones, esters, ethers, acetates, nitriles, terpene hydrocarbons, heterocyclic nitrogen or sulfur compounds, as well as essential oils of natural or synthetic origin. Many of these ingredients are also listed in reference texts such as the book by S. Arctander, Perfume and Flavor Chemicals, 1969, Montclair, New Jersey, USA, or its more recent versions, or in other works by similar in nature, as well as in more recent scientific and patent literature relating to the art of perfumery.
- the stability of the perfume compositions of the invention is quite appreciable and suitable for the storage times typical for this type of product, thanks in particular to the presence of a surfactant system whose hydrophilic-lipophilic balance (HLB) is greater or equal to 10, preferably greater than or equal to 15.
- a surfactant system whose hydrophilic-lipophilic balance (HLB) is greater or equal to 10, preferably greater than or equal to 15.
- HLB hydrophilic-lipophilic balance
- surfactant system is meant here a surfactant alone or a mixture of two or more agents of this type.
- the surfactant system according to the invention proves to be particularly advantageous insofar as it makes it possible to obtain a stable emulsion for a wide variety of perfuming ingredients used in the oily phase of the emulsion.
- the surfactant system of the invention remains suitable for a wide variety of perfume ingredients used and makes it possible to obtain an emulsion satisfying the stability criteria necessary for the storage of the product.
- the surfactant system used according to the invention comprises non-ionic polyethox or polypropoxylated surfactants.
- the surfactant system used according to the invention preferably consists of at least one nonionic surfactant belonging to one of the families consisting of polyethylene glycol stearylethers, polyethylene glycol (n) oleyl ethers, polyethylene glycol nonylphenyl ethers (n) and polysorbates.
- Other polyethylene glycol alkyl ethers can be used according to the invention. The use of mixtures of these surfactants has been found to be particularly advantageous.
- the HLB value of the system must be greater than or equal to 10.
- a surfactant system consisting of an agent chosen from the family of stearic ethers of polyethylene glycol (n) is used.
- n polyethylene glycol
- the surfactant system according to the invention is used in proportions of between 0.1 and 18%, preferably between 1 and 10% by weight relative to the total weight of the emulsion. The best results have been obtained using 3 to 8% by weight of surfactant.
- the oily phase of the oil-in-water emulsion of the invention consists essentially of perfuming ingredients. Other substances may still be present in the oily phase and have given good results.
- Isopar ® isoparaffin fractions marketed under the name Isopar ®, for example Isopar (N, by Exxon Chemicals Company, or another fraction of paraffin , Gemseal 60 sold by Total, these substances are used as stabilizers for the emulsion.
- the variation over time of the average size of the drops of the emulsion of the invention constitutes an essential characteristic of the perfume composition.
- this very characteristic variation of the emulsion as a thermodynamically unstable dispersed system is however sufficiently small to make the product quite interesting in the sense that the current phenomena of destabilization such as the creaming effect or even the sedimentation are avoided.
- this variation can be measured by a dynamic light scattering method (described in detail in Example 1) which makes it possible to establish that during the first month following the formulation of the emulsion according to the invention the variation in the average size of the drops of the system, at a temperature of 45 ° C., is in a range from 0.1 to 30 nm.
- the perfume compositions according to the invention can be used for different types of applications of perfumery products such as emulsions of perfume, eau de toilette or eau de Cologne without alcohol, capable of being vaporized on the skin or the hair. They can also be used to perfume other types of surfaces such as fabrics, wood, glass. In another embodiment, the compositions of the invention can even perfume the ambient air and thus be used as perfume diffusers.
- the surfactant system made liquid and the oily phase were mixed at room temperature until a homogeneous mixture was obtained, before adding the aqueous phase.
- the mixture was then heated to obtain a coarse emulsion, while maintaining it under gentle stirring (200 rpm). As the temperature increased, the emulsion became finer and then more viscous. The heating was then stopped and the emulsion was cooled to room temperature (25 °), still with stirring.
- a finely dispersed oil-in-water emulsion with a translucent appearance was thus obtained (80% transmission at a wavelength of 600 nm, a temperature of 25 °, in a tank of 1 cm thickness) with bluish reflections.
- the particle size was measured using a granulometer (Autosizer 4700, origin: Malvern; measurement angle: 90 °; laser wavelength: 532 nm; measurement temperature: 25 °; mode of single-mode intensity analysis).
- the average particle size of the present emulsion was 29.5 nm after formulation. After one month at 45 °, the average size of the drops had varied by 20 nm.
- the emulsion was prepared in a similar manner to that prepared in Example 1.
- the emulsion was prepared in a similar manner to that prepared in Example 1.
- the composition obtained was translucent (61.5% transmission at 600 nm, at a temperature of 25 °, in a tank 1 cm thick ).
- the average particle size was 36.5 nm after the formulation and its variation after one month at 45 °, of 1 nm.
- the emulsion was prepared in a similar manner to that prepared in Example 1.
- the composition obtained was translucent (transmission of 14.4% at 600 nm, at a temperature of 25 °, in a tank 1 cm thick ).
- the average particle size was 37.5 nm after the formulation and its variation after one month at 45 ° from 2 nm.
- the emulsion was prepared in a similar manner to that prepared in Example 1.
- the composition obtained was translucent (transmission of 45.7% at 600 nm, at a temperature of 25 °, in a tank 1 cm thick).
- the average particle size was 46 nm after the formulation and its variation after one month at 45 ° by 0.5 nm.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Fats And Perfumes (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14169287.1A EP2786736A1 (fr) | 2000-10-20 | 2001-10-17 | Procédé de fabrication d'une composition parfumante sans alcool |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH20602000 | 2000-10-20 | ||
CH206000 | 2000-10-20 | ||
PCT/IB2001/001961 WO2002032390A1 (fr) | 2000-10-20 | 2001-10-17 | Composition parfumante sans alcool |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14169287.1A Division EP2786736A1 (fr) | 2000-10-20 | 2001-10-17 | Procédé de fabrication d'une composition parfumante sans alcool |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1328248A1 true EP1328248A1 (fr) | 2003-07-23 |
Family
ID=4567345
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14169287.1A Withdrawn EP2786736A1 (fr) | 2000-10-20 | 2001-10-17 | Procédé de fabrication d'une composition parfumante sans alcool |
EP01974619A Ceased EP1328248A1 (fr) | 2000-10-20 | 2001-10-17 | Composition parfumante sans alcool |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14169287.1A Withdrawn EP2786736A1 (fr) | 2000-10-20 | 2001-10-17 | Procédé de fabrication d'une composition parfumante sans alcool |
Country Status (7)
Country | Link |
---|---|
US (1) | US6774101B2 (fr) |
EP (2) | EP2786736A1 (fr) |
JP (1) | JP4429600B2 (fr) |
AU (1) | AU2001294132A1 (fr) |
BR (1) | BR0107351B1 (fr) |
CA (1) | CA2394175C (fr) |
WO (1) | WO2002032390A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2365000A2 (fr) | 2005-05-18 | 2011-09-14 | Ablynx N.V. | NanobodiesTM améliorés contre le facteur alpha de la nécrose des tumeurs |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1399124B1 (fr) * | 2001-06-11 | 2007-10-10 | Firmenich Sa | Emulsion parfumee transparente et stable |
US20090010972A1 (en) * | 2007-03-16 | 2009-01-08 | Barbara Marie Modafari | Deodorant compositions |
US8741062B2 (en) * | 2008-04-22 | 2014-06-03 | Picosun Oy | Apparatus and methods for deposition reactors |
EP2127632A1 (fr) | 2008-05-29 | 2009-12-02 | Coty Inc. | Composition de parfum avec contenu en alcool réduit |
FR2952531B1 (fr) * | 2009-11-19 | 2015-03-20 | Oreal | Composition parfumante aqueuse comprenant au moins un alcane lineaire volatil ; procede de parfumage |
KR20130102460A (ko) * | 2010-05-10 | 2013-09-17 | 세게티스, 인코포레이티드. | 알킬 케탈 에스터를 함유하는 퍼스널 케어 조제물 및 제조방법 |
WO2014047428A1 (fr) | 2012-09-21 | 2014-03-27 | Segetis, Inc. | Compositions de nettoyage, de tensioactif et de soins personnels |
GB201308236D0 (en) | 2013-05-08 | 2013-06-12 | Givaudan Sa | Improvements in or relating to organic compounds |
KR102061209B1 (ko) | 2013-08-28 | 2019-12-31 | (주)더페이스샵 | 비대칭의 극성 오일을 포함하는 향수 조성물 |
EP2915580B1 (fr) | 2014-03-07 | 2020-04-29 | Symrise AG | Préparations aux propriétés physiques améliorées |
FR3035788B1 (fr) | 2015-05-04 | 2019-11-22 | Total Marketing Services | Nano-emulsion cosmetique |
US20190117530A1 (en) * | 2015-10-09 | 2019-04-25 | Fernando Thome Kreutz | Nanoemulsion compositions and methods |
US10980717B2 (en) | 2019-02-05 | 2021-04-20 | Elc Management Llc | Aqueous perfume compositions |
US11291618B2 (en) | 2019-03-15 | 2022-04-05 | Elc Management Llc | Long wear skincare compositions |
EP3795134B1 (fr) * | 2019-09-19 | 2023-05-10 | Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC | Compositions parfumantes, stables et possédant de bonnes propriétés de pulvérisation |
US11129788B1 (en) | 2020-03-24 | 2021-09-28 | Elc Management Llc | Sprayable film forming compositions for improving the performance of topical preparations |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2676924B1 (fr) | 1991-05-31 | 1995-02-03 | Saint Laurent Parfums Yves | Microemulsion contenant un concentre parfumant et produit correspondant. |
EP0572080B1 (fr) * | 1992-05-29 | 1995-11-15 | Quest International B.V. | Microémulsions aqueuses de parfums |
EP0571677A1 (fr) * | 1992-05-29 | 1993-12-01 | Unilever Plc | Microémulsions aqueuses de parfums |
FR2703926B1 (fr) | 1993-04-13 | 1997-10-10 | Shiseido International France | Micro-émulsion stable procurant une pulvérisation à contact sec, procédé de préparation et dispositif de mise en oeuvre. |
US5468725A (en) * | 1993-07-01 | 1995-11-21 | International Flvos & Fragrances Inc. | Alcohol free perfume |
US5283056A (en) * | 1993-07-01 | 1994-02-01 | International Flavors & Fragrances Inc. | Transparent oil-in-water microemulsion flavor or fragrance concentrate, process for preparing same, mouthwash or perfume composition containing said transparent microemulsion concentrate, and process for preparing same |
US5585343A (en) * | 1993-11-02 | 1996-12-17 | Givaudan-Roure Corporation | Low VOC perfume formulations |
JPH08225429A (ja) | 1995-02-22 | 1996-09-03 | Shiseido Co Ltd | 香料組成物 |
FR2730932B1 (fr) | 1995-02-27 | 1997-04-04 | Oreal | Nanoemulsion transparente a base de lipides amphiphiles non-ioniques fluides et utilisation en cosmetique ou en dermopharmacie |
-
2001
- 2001-10-17 WO PCT/IB2001/001961 patent/WO2002032390A1/fr active Application Filing
- 2001-10-17 BR BRPI0107351-6A patent/BR0107351B1/pt not_active IP Right Cessation
- 2001-10-17 EP EP14169287.1A patent/EP2786736A1/fr not_active Withdrawn
- 2001-10-17 CA CA2394175A patent/CA2394175C/fr not_active Expired - Fee Related
- 2001-10-17 EP EP01974619A patent/EP1328248A1/fr not_active Ceased
- 2001-10-17 JP JP2002535629A patent/JP4429600B2/ja not_active Expired - Fee Related
- 2001-10-17 AU AU2001294132A patent/AU2001294132A1/en not_active Abandoned
-
2002
- 2002-06-10 US US10/167,292 patent/US6774101B2/en not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
See references of WO0232390A1 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2365000A2 (fr) | 2005-05-18 | 2011-09-14 | Ablynx N.V. | NanobodiesTM améliorés contre le facteur alpha de la nécrose des tumeurs |
EP2479191A2 (fr) | 2005-05-18 | 2012-07-25 | Ablynx N.V. | NanobodiesTM améliorés contre le facteur alpha de la nécrose des tumeurs |
Also Published As
Publication number | Publication date |
---|---|
JP2004511508A (ja) | 2004-04-15 |
BR0107351A (pt) | 2002-09-17 |
US20030007986A1 (en) | 2003-01-09 |
JP4429600B2 (ja) | 2010-03-10 |
CA2394175C (fr) | 2011-01-04 |
BR0107351B1 (pt) | 2014-12-02 |
EP2786736A1 (fr) | 2014-10-08 |
WO2002032390A1 (fr) | 2002-04-25 |
US6774101B2 (en) | 2004-08-10 |
AU2001294132A1 (en) | 2002-04-29 |
CA2394175A1 (fr) | 2002-04-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2319271C (fr) | Composition parfumante transparente | |
CA2394175C (fr) | Composition parfumante sans alcool | |
RU2605345C2 (ru) | Парфюмерные композиции и их применение | |
RU2605538C2 (ru) | Парфюмерные композиции и их применение | |
WO2014155019A2 (fr) | Composition hydro-alcoolique parfumante contenant un ether aliphatique | |
US7226901B2 (en) | Stable transparent perfuming emulsion | |
EP3160433B1 (fr) | Composition parfumante améliorée. | |
EP0809485B1 (fr) | Utilisation du 4-tert-butyl-1-cyclohexanol en tant qu'antioxydant | |
EP4142678B1 (fr) | Composition parfumante | |
WO2002102339A1 (fr) | Emulsion parfumante transparente stable | |
WO2023067179A1 (fr) | Complexe parfumant, composition parfumante et composition aqueuse parfumée d'origine naturelle | |
FR2960149A1 (fr) | Composition parfumante comprenant un melange d'alcanes ; procedes de parfumage | |
FR2967906A1 (fr) | Composition parfumante alcoolique comprenant un terpolymere anionique ; procede de parfumage | |
FR2983068A1 (fr) | Composition transparente de type emulsion pickering a base de particules d'aerogel hydrophobe | |
FR2983064A1 (fr) | Composition cosmetique bicolore de type emulsion. | |
FR2983066A1 (fr) | Composition deodorante liquide de type emulsion pickering. | |
FR2983067A1 (fr) | Composition parfumante de type emulsion pickering comprenant des particules de silicate de magnesium, de l'alcool et un polyalkylene glycol | |
JP2007097943A (ja) | 液体芳香消臭剤組成物 | |
MXPA00007618A (en) | Transparent perfume composition | |
FR2922762A1 (fr) | Composition parfumante comprenant au moins un alkylether de cellulose et/ou un alkylether d'alkylcellulose. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030520 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
17Q | First examination report despatched |
Effective date: 20050916 |
|
APBK | Appeal reference recorded |
Free format text: ORIGINAL CODE: EPIDOSNREFNE |
|
APBN | Date of receipt of notice of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA2E |
|
APBR | Date of receipt of statement of grounds of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA3E |
|
APAF | Appeal reference modified |
Free format text: ORIGINAL CODE: EPIDOSCREFNE |
|
APBX | Invitation to file observations in appeal sent |
Free format text: ORIGINAL CODE: EPIDOSNOBA2E |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
APBT | Appeal procedure closed |
Free format text: ORIGINAL CODE: EPIDOSNNOA9E |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20140522 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0007460000 Ipc: A61K0008060000 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0007460000 Ipc: A61K0008060000 Effective date: 20150121 |