EP1288296A3 - Method and reagent for inhibiting HBV viral replication - Google Patents
Method and reagent for inhibiting HBV viral replication Download PDFInfo
- Publication number
- EP1288296A3 EP1288296A3 EP02008657A EP02008657A EP1288296A3 EP 1288296 A3 EP1288296 A3 EP 1288296A3 EP 02008657 A EP02008657 A EP 02008657A EP 02008657 A EP02008657 A EP 02008657A EP 1288296 A3 EP1288296 A3 EP 1288296A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- reagent
- viral replication
- hbv viral
- inhibiting hbv
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Applications Claiming Priority (57)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88268992A | 1992-05-11 | 1992-05-11 | |
US882689 | 1992-05-11 | ||
US88292192A | 1992-05-14 | 1992-05-14 | |
US88282492A | 1992-05-14 | 1992-05-14 | |
US88271492A | 1992-05-14 | 1992-05-14 | |
US88288692A | 1992-05-14 | 1992-05-14 | |
US88442292A | 1992-05-14 | 1992-05-14 | |
US88282392A | 1992-05-14 | 1992-05-14 | |
US88288892A | 1992-05-14 | 1992-05-14 | |
US88443192A | 1992-05-14 | 1992-05-14 | |
US88452192A | 1992-05-14 | 1992-05-14 | |
US88433392A | 1992-05-14 | 1992-05-14 | |
US88271392A | 1992-05-14 | 1992-05-14 | |
US88292292A | 1992-05-14 | 1992-05-14 | |
US88407392A | 1992-05-14 | 1992-05-14 | |
US88382392A | 1992-05-14 | 1992-05-14 | |
US88443692A | 1992-05-14 | 1992-05-14 | |
US88271292A | 1992-05-14 | 1992-05-14 | |
US88288992A | 1992-05-14 | 1992-05-14 | |
US88407492A | 1992-05-14 | 1992-05-14 | |
US88384992A | 1992-05-14 | 1992-05-14 | |
US884422 | 1992-05-14 | ||
US882921 | 1992-05-14 | ||
US882889 | 1992-05-14 | ||
US882922 | 1992-05-14 | ||
US884074 | 1992-05-14 | ||
US884521 | 1992-05-14 | ||
US884431 | 1992-05-14 | ||
US882886 | 1992-05-14 | ||
US882824 | 1992-05-14 | ||
US884436 | 1992-05-14 | ||
US882713 | 1992-05-14 | ||
US884333 | 1992-05-14 | ||
US882823 | 1992-05-14 | ||
US882888 | 1992-05-14 | ||
US884073 | 1992-05-14 | ||
US883849 | 1992-05-14 | ||
US882712 | 1992-05-14 | ||
US92373892A | 1992-07-31 | 1992-07-31 | |
US923738 | 1992-07-31 | ||
US93585492A | 1992-08-26 | 1992-08-26 | |
US93608692A | 1992-08-26 | 1992-08-26 | |
US935854 | 1992-08-26 | ||
US936086 | 1992-08-26 | ||
US94835992A | 1992-09-18 | 1992-09-18 | |
US948359 | 1992-09-18 | ||
US96332292A | 1992-10-15 | 1992-10-15 | |
US963322 | 1992-10-15 | ||
US98713392A | 1992-12-07 | 1992-12-07 | |
US98712992A | 1992-12-07 | 1992-12-07 | |
US987130 | 1992-12-07 | ||
US987133 | 1992-12-07 | ||
US987129 | 1992-12-07 | ||
US07/987,130 US5496698A (en) | 1992-08-26 | 1992-12-07 | Method of isolating ribozyme targets |
EP93910893A EP0642589A4 (en) | 1992-05-11 | 1993-04-29 | Method and reagent for inhibiting viral replication. |
US882714 | 1997-06-25 | ||
US883823 | 1997-06-27 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93910893A Division EP0642589A4 (en) | 1992-05-11 | 1993-04-29 | Method and reagent for inhibiting viral replication. |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1288296A2 EP1288296A2 (en) | 2003-03-05 |
EP1288296A3 true EP1288296A3 (en) | 2003-03-12 |
Family
ID=27586837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02008657A Withdrawn EP1288296A3 (en) | 1992-05-11 | 1993-04-29 | Method and reagent for inhibiting HBV viral replication |
Country Status (1)
Country | Link |
---|---|
EP (1) | EP1288296A3 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8318423B2 (en) * | 2004-07-06 | 2012-11-27 | Focus Diagnostics, Inc. | Methods and compositions for detecting rhinoviruses |
US7354719B2 (en) | 2004-12-08 | 2008-04-08 | Gen-Probe Incorporated | Detection of nucleic acids from multiple types of human papillomaviruses |
US8524676B2 (en) * | 2005-09-08 | 2013-09-03 | Sarepta Therapeutics, Inc. | Method for treating enterovirus or rhinovirus infection using antisense antiviral compounds |
SG10201914029RA (en) * | 2016-10-14 | 2020-03-30 | Precision Biosciences Inc | Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988010301A1 (en) * | 1987-06-22 | 1988-12-29 | Mccormick And Jones Engineering Ltd. | Hepatitis b surface antigen vaccine |
EP0374817A2 (en) * | 1988-12-21 | 1990-06-27 | Takeda Chemical Industries, Ltd. | Method for disrupting virus particles |
WO1991004319A1 (en) * | 1989-09-25 | 1991-04-04 | Innovir Laboratories, Inc. | Therapeutic ribozyme compositions and expression vectors |
EP0558944A2 (en) * | 1992-02-06 | 1993-09-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | RNA and DNA molecules for producing virus resistance |
-
1993
- 1993-04-29 EP EP02008657A patent/EP1288296A3/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988010301A1 (en) * | 1987-06-22 | 1988-12-29 | Mccormick And Jones Engineering Ltd. | Hepatitis b surface antigen vaccine |
EP0374817A2 (en) * | 1988-12-21 | 1990-06-27 | Takeda Chemical Industries, Ltd. | Method for disrupting virus particles |
WO1991004319A1 (en) * | 1989-09-25 | 1991-04-04 | Innovir Laboratories, Inc. | Therapeutic ribozyme compositions and expression vectors |
EP0558944A2 (en) * | 1992-02-06 | 1993-09-08 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | RNA and DNA molecules for producing virus resistance |
Non-Patent Citations (4)
Title |
---|
43rd Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Chicago, Illinois, USA, October 31-November 3, 1992. * |
DROPULIC B ET AL: "FUNCTIONAL CHARACTERIZATION OF A U5 RIBOZYME: INTRACELLULAR SUPPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 EXPRESSION", JOURNAL OF VIROLOGY, vol. 66, no. 3, 1 March 1992 (1992-03-01), pages 1432 - 1441, XP002026933, ISSN: 0022-538X * |
NARAYAN P ET AL: "NUCLEASE RESISTANT RIBOZYMES AGAINST HEPATITIS B SURFACE ANTIGEN MRNA", JOURNAL OF CELLULAR BIOCHEMISTRY. SUPPLEMENT, vol. 17, PART E, 12 April 1993 (1993-04-12), pages 213, XP000653188, ISSN: 0733-1959 * |
WEIZSAECKER F V ET AL: "Ribozyme mediated cleavage of hepatitis B and duck hepatitis B virus RNA.", HEPATOLOGY, vol. 16, no. 4 PART 2, 1992, pages 88A, XP001133829, ISSN: 0270-9139 * |
Also Published As
Publication number | Publication date |
---|---|
EP1288296A2 (en) | 2003-03-05 |
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