EP1287159A4 - Traitement enzymatique des proteines de lactoserum permettant d'obtenir des peptides anti-hypertension, produits obtenus et traitement de l'hypertension chez les mammiferes - Google Patents

Traitement enzymatique des proteines de lactoserum permettant d'obtenir des peptides anti-hypertension, produits obtenus et traitement de l'hypertension chez les mammiferes

Info

Publication number
EP1287159A4
EP1287159A4 EP01933181A EP01933181A EP1287159A4 EP 1287159 A4 EP1287159 A4 EP 1287159A4 EP 01933181 A EP01933181 A EP 01933181A EP 01933181 A EP01933181 A EP 01933181A EP 1287159 A4 EP1287159 A4 EP 1287159A4
Authority
EP
European Patent Office
Prior art keywords
treatment
hypertension
mammals
production
resulting products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01933181A
Other languages
German (de)
English (en)
Other versions
EP1287159A1 (fr
Inventor
Martin E Davis
Anand Rao
Sylvie Gauthier
Yves Pouliot
Line Gourley
Ann Francoise Allain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Davisco Foods International Inc
Original Assignee
Davisco Foods International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/567,283 external-priority patent/US6630320B1/en
Priority claimed from US09/702,068 external-priority patent/US6998259B1/en
Application filed by Davisco Foods International Inc filed Critical Davisco Foods International Inc
Publication of EP1287159A1 publication Critical patent/EP1287159A1/fr
Publication of EP1287159A4 publication Critical patent/EP1287159A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
EP01933181A 2000-05-08 2001-05-08 Traitement enzymatique des proteines de lactoserum permettant d'obtenir des peptides anti-hypertension, produits obtenus et traitement de l'hypertension chez les mammiferes Withdrawn EP1287159A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US702068 1991-05-17
US09/567,283 US6630320B1 (en) 2000-05-08 2000-05-08 Treatment of hypertension in mammals with hydrolyzed whey proteins
US567283 2000-05-08
US09/702,068 US6998259B1 (en) 1999-05-20 2000-10-30 Enzymatic treatment of whey proteins for the production of antihypertensive peptides and the resulting products
PCT/US2001/014797 WO2001085984A1 (fr) 2000-05-08 2001-05-08 Traitement enzymatique des proteines de lactoserum permettant d'obtenir des peptides anti-hypertension, produits obtenus et traitement de l'hypertension chez les mammiferes

Publications (2)

Publication Number Publication Date
EP1287159A1 EP1287159A1 (fr) 2003-03-05
EP1287159A4 true EP1287159A4 (fr) 2005-02-09

Family

ID=27074429

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01933181A Withdrawn EP1287159A4 (fr) 2000-05-08 2001-05-08 Traitement enzymatique des proteines de lactoserum permettant d'obtenir des peptides anti-hypertension, produits obtenus et traitement de l'hypertension chez les mammiferes

Country Status (7)

Country Link
EP (1) EP1287159A4 (fr)
JP (1) JP2004519204A (fr)
AU (1) AU2001259625A1 (fr)
CA (1) CA2415688A1 (fr)
MX (1) MXPA02011018A (fr)
NZ (1) NZ523036A (fr)
WO (1) WO2001085984A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ508867A (en) 1998-06-17 2003-11-28 New Zealand Dairy Board Bioactive whey protein hydrolysate
EP1517619B1 (fr) 2002-07-01 2007-01-03 Unilever N.V. Composition induisant la satiete
EP1466529A1 (fr) * 2003-04-07 2004-10-13 Chr. Hansen A/S Composition destinée à reduire la fréquence cardiaque
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
WO2004098310A1 (fr) * 2003-05-05 2004-11-18 Unilever N.V. Peptides ayant un effet inhibiteur sur l'enzyme ace
ES2253036B1 (es) 2003-07-31 2007-07-16 Consejo Sup. Investig. Cientificas Peptidos bioactivos derivados de proteinas de la clara de huevo mediante hidrolisis enzimatica.
CA2547737A1 (fr) * 2003-12-15 2005-06-30 Unilever Plc Peptides presentant un effet inhibiteur de l'eca
EP1685764A1 (fr) 2005-01-27 2006-08-02 Globus Egg Sciences B.V. Produits fonctionnels alimentaires hypotenseurs
NL1026931C2 (nl) * 2004-08-31 2006-03-01 Friesland Brands Bv ACE-remmende wei-hydrolysaten.
EP1796480B1 (fr) 2004-09-03 2011-11-09 Chr. Hansen A/S Lait fermente comprenant un ligand de recepteur et utilisations correspondantes
FR2876389B1 (fr) * 2004-10-13 2007-05-25 Viridis Sa Hydrolysats de proteines blanches de luzerne
ES2319475B1 (es) 2005-06-08 2010-02-16 Consejo Superior Investig. Cientificas Peptidos bioactivos identificados en hidrolizados enzimaticos de caseinas lacteas y procedimiento de obtencion.
DE102008032828A1 (de) 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
CN110590916A (zh) 2013-04-25 2019-12-20 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f多肽
WO2017005848A1 (fr) 2015-07-07 2017-01-12 Janssen Vaccines & Prevention B.V. Polypeptides f du vrs de pré-fusion solubles stabilisés
EP3319633B1 (fr) 2015-07-07 2020-11-11 Janssen Vaccines & Prevention B.V. Vaccin contre le vrs
EA201892250A1 (ru) 2016-04-05 2019-03-29 Янссен Вэксинс Энд Превеншн Б.В. Вакцина против rsv
AU2017248021B2 (en) 2016-04-05 2021-08-12 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F proteins
PL3464331T3 (pl) 2016-05-30 2021-04-19 Janssen Vaccines & Prevention B.V. Stabilizowane przedfuzyjne białka F RSV
CA3061278A1 (fr) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Procedes et compositions pour induire une immunite protectrice contre l'infection par le vrs
WO2018210871A1 (fr) 2017-05-17 2018-11-22 Janssen Vaccines & Prevention B.V. Procédés et compositions pour induire une immunité protectrice contre l'infection par le vrs
SG11202001458SA (en) 2017-09-15 2020-03-30 Janssen Vaccines & Prevention Bv Method for the safe induction of immunity against rsv

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04282400A (ja) * 1991-03-12 1992-10-07 Calpis Food Ind Co Ltd:The アンジオテンシン変換酵素阻害ペプチド組成物
JPH06345664A (ja) * 1993-06-11 1994-12-20 Takako Tomita 新規な血圧上昇抑制用組成物
EP0671126A1 (fr) * 1992-11-30 1995-09-13 Morinaga Milk Industry Co., Ltd. Proteine de petit-lait a faible teneur en phosphore, procede de production de ladite proteine, hydrolysat de ladite proteine purifiee et procede de production dudit hydrolysat
EP0821968A2 (fr) * 1996-08-02 1998-02-04 The Calpis Food Industry Co., Ltd. Agent antihypertensif et procédé pour sa préparation
JPH1033115A (ja) * 1996-07-24 1998-02-10 Nouchikusangiyou Shinko Jigyodan ホエー飲料とその製造法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3149199B2 (ja) * 1991-03-12 2001-03-26 カルピス株式会社 アンジオテンシン変換酵素阻害ペプチド

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04282400A (ja) * 1991-03-12 1992-10-07 Calpis Food Ind Co Ltd:The アンジオテンシン変換酵素阻害ペプチド組成物
EP0671126A1 (fr) * 1992-11-30 1995-09-13 Morinaga Milk Industry Co., Ltd. Proteine de petit-lait a faible teneur en phosphore, procede de production de ladite proteine, hydrolysat de ladite proteine purifiee et procede de production dudit hydrolysat
JPH06345664A (ja) * 1993-06-11 1994-12-20 Takako Tomita 新規な血圧上昇抑制用組成物
JPH1033115A (ja) * 1996-07-24 1998-02-10 Nouchikusangiyou Shinko Jigyodan ホエー飲料とその製造法
EP0821968A2 (fr) * 1996-08-02 1998-02-04 The Calpis Food Industry Co., Ltd. Agent antihypertensif et procédé pour sa préparation

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ABUBAKAR A ET AL: "Structural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion.", JOURNAL OF DAIRY SCIENCE. DEC 1998, vol. 81, no. 12, December 1998 (1998-12-01), pages 3131 - 3138, XP002937027, ISSN: 0022-0302 *
DATABASE WPI Section Ch Week 199248, Derwent World Patents Index; Class B04, AN 1992-392238, XP002311023 *
DATABASE WPI Section Ch Week 199510, Derwent World Patents Index; Class B04, AN 1995-070230, XP002311025 *
DATABASE WPI Section Ch Week 199816, Derwent World Patents Index; Class B04, AN 1998-172040, XP002311024 *
MULLALLY MARGARET M ET AL: "Angiotensin-I-converting enzyme inhibitory activities of gastric and pancreatic proteinase digests of whey proteins", INTERNATIONAL DAIRY JOURNAL, vol. 7, no. 5, May 1997 (1997-05-01), pages 299 - 303, XP000853725, ISSN: 0958-6946 *
PIHLANTO-LEPPALA ANNE ET AL: "Angiotensin I converting enzyme inhibitory peptides derived from bovine milk proteins", INTERNATIONAL DAIRY JOURNAL, vol. 8, no. 4, April 1998 (1998-04-01), pages 325 - 331, XP000853723, ISSN: 0958-6946 *
See also references of WO0185984A1 *

Also Published As

Publication number Publication date
EP1287159A1 (fr) 2003-03-05
CA2415688A1 (fr) 2001-11-15
NZ523036A (en) 2004-04-30
WO2001085984A1 (fr) 2001-11-15
AU2001259625A1 (en) 2001-11-20
JP2004519204A (ja) 2004-07-02
MXPA02011018A (es) 2004-08-19

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