EP1272173A4 - Methods for inhibiting angiogenesis and tumor growth - Google Patents
Methods for inhibiting angiogenesis and tumor growthInfo
- Publication number
- EP1272173A4 EP1272173A4 EP01922734A EP01922734A EP1272173A4 EP 1272173 A4 EP1272173 A4 EP 1272173A4 EP 01922734 A EP01922734 A EP 01922734A EP 01922734 A EP01922734 A EP 01922734A EP 1272173 A4 EP1272173 A4 EP 1272173A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- tumor growth
- inhibiting angiogenesis
- angiogenesis
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19226000P | 2000-03-27 | 2000-03-27 | |
US192260P | 2000-03-27 | ||
PCT/US2001/009785 WO2001072297A1 (en) | 2000-03-27 | 2001-03-27 | Methods for inhibiting angiogenesis and tumor growth |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1272173A1 EP1272173A1 (en) | 2003-01-08 |
EP1272173A4 true EP1272173A4 (en) | 2006-05-03 |
Family
ID=22708924
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01924359A Ceased EP1276713A4 (en) | 2000-03-27 | 2001-03-27 | Inhibition of angiogenesis and tumor growth |
EP01922734A Withdrawn EP1272173A4 (en) | 2000-03-27 | 2001-03-27 | Methods for inhibiting angiogenesis and tumor growth |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01924359A Ceased EP1276713A4 (en) | 2000-03-27 | 2001-03-27 | Inhibition of angiogenesis and tumor growth |
Country Status (15)
Country | Link |
---|---|
EP (2) | EP1276713A4 (en) |
JP (2) | JP2003528850A (en) |
KR (2) | KR100776185B1 (en) |
CN (2) | CN1229339C (en) |
AU (4) | AU4949901A (en) |
CA (3) | CA2403630C (en) |
CZ (2) | CZ20023510A3 (en) |
HU (2) | HUP0301797A3 (en) |
MX (2) | MXPA02009504A (en) |
NO (2) | NO328969B1 (en) |
PL (2) | PL205134B1 (en) |
RU (2) | RU2269339C2 (en) |
SK (2) | SK14852002A3 (en) |
WO (2) | WO2001072297A1 (en) |
ZA (2) | ZA200208628B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GEP20115205B (en) | 2003-10-23 | 2011-04-26 | Otsuka Pharma Co Ltd | Controlled release sterile injectable aripiprazole formulation and method |
US9457026B2 (en) | 2007-07-31 | 2016-10-04 | Otsuka Pharmaceutical Co., Ltd. | Methods for producing aripiprazole suspension and freeze-dried formulation |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4511504A (en) * | 1983-04-26 | 1985-04-16 | G.D. Searle & Co. | Carboxyalkyl peptide derivatives |
WO1994025435A1 (en) * | 1993-04-27 | 1994-11-10 | Celltech Limited | Peptidyl derivatives and their use as metalloproteinase inhibitors |
US5442110A (en) * | 1991-11-06 | 1995-08-15 | Yamanouchi Pharmaceutical Co., Ltd. | Hydroxamic acid derivative |
WO1998035231A1 (en) * | 1997-02-07 | 1998-08-13 | The Scripps Research Institute | Convergent synthesis of combinatorial library |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9405076D0 (en) * | 1994-03-16 | 1994-04-27 | Inst Of Ophtalmology | A medical use of matrix metalloproteinase inhibitors |
AUPO104496A0 (en) * | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Angiogenic inhibitory compounds |
JP2002514180A (en) * | 1996-09-04 | 2002-05-14 | ワーナー―ランバート・コンパニー | Compounds for inhibiting matrix metalloproteinases and methods thereof |
ATE353640T1 (en) * | 1998-03-27 | 2007-03-15 | Genentech Inc | ANTAGONISTS FOR THE TREATMENT OF CD11/CD18 ADHESION RECEPTOR-MEDIATED DISEASES |
-
2001
- 2001-03-27 SK SK1485-2002A patent/SK14852002A3/en not_active Application Discontinuation
- 2001-03-27 RU RU2002128736/15A patent/RU2269339C2/en not_active IP Right Cessation
- 2001-03-27 KR KR1020027012720A patent/KR100776185B1/en not_active IP Right Cessation
- 2001-03-27 AU AU4949901A patent/AU4949901A/en active Pending
- 2001-03-27 CZ CZ20023510A patent/CZ20023510A3/en unknown
- 2001-03-27 CN CNB018097448A patent/CN1229339C/en not_active Expired - Fee Related
- 2001-03-27 WO PCT/US2001/009785 patent/WO2001072297A1/en active IP Right Grant
- 2001-03-27 WO PCT/US2001/009756 patent/WO2001072699A1/en active IP Right Grant
- 2001-03-27 CZ CZ20023509A patent/CZ20023509A3/en unknown
- 2001-03-27 CN CNB01809743XA patent/CN1245967C/en not_active Expired - Fee Related
- 2001-03-27 RU RU2002128751/04A patent/RU2276133C2/en not_active IP Right Cessation
- 2001-03-27 JP JP2001570612A patent/JP2003528850A/en active Pending
- 2001-03-27 HU HU0301797A patent/HUP0301797A3/en unknown
- 2001-03-27 MX MXPA02009504A patent/MXPA02009504A/en active IP Right Grant
- 2001-03-27 MX MXPA02009510A patent/MXPA02009510A/en active IP Right Grant
- 2001-03-27 SK SK1484-2002A patent/SK14842002A3/en not_active Application Discontinuation
- 2001-03-27 HU HU0301621A patent/HUP0301621A3/en unknown
- 2001-03-27 KR KR1020027012724A patent/KR100767616B1/en not_active IP Right Cessation
- 2001-03-27 PL PL366316A patent/PL205134B1/en not_active IP Right Cessation
- 2001-03-27 EP EP01924359A patent/EP1276713A4/en not_active Ceased
- 2001-03-27 JP JP2001570258A patent/JP2003528140A/en not_active Withdrawn
- 2001-03-27 AU AU2001249499A patent/AU2001249499B2/en not_active Ceased
- 2001-03-27 AU AU2001251018A patent/AU2001251018B2/en not_active Ceased
- 2001-03-27 CA CA002403630A patent/CA2403630C/en not_active Expired - Fee Related
- 2001-03-27 EP EP01922734A patent/EP1272173A4/en not_active Withdrawn
- 2001-03-27 CA CA002659030A patent/CA2659030A1/en not_active Abandoned
- 2001-03-27 CA CA2403871A patent/CA2403871C/en not_active Expired - Fee Related
- 2001-03-27 PL PL01358272A patent/PL358272A1/en not_active Application Discontinuation
- 2001-03-27 AU AU5101801A patent/AU5101801A/en active Pending
-
2002
- 2002-09-24 NO NO20024578A patent/NO328969B1/en not_active IP Right Cessation
- 2002-09-24 NO NO20024576A patent/NO20024576L/en not_active Application Discontinuation
- 2002-10-24 ZA ZA200208628A patent/ZA200208628B/en unknown
- 2002-10-24 ZA ZA200208626A patent/ZA200208626B/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4511504A (en) * | 1983-04-26 | 1985-04-16 | G.D. Searle & Co. | Carboxyalkyl peptide derivatives |
US5442110A (en) * | 1991-11-06 | 1995-08-15 | Yamanouchi Pharmaceutical Co., Ltd. | Hydroxamic acid derivative |
WO1994025435A1 (en) * | 1993-04-27 | 1994-11-10 | Celltech Limited | Peptidyl derivatives and their use as metalloproteinase inhibitors |
WO1998035231A1 (en) * | 1997-02-07 | 1998-08-13 | The Scripps Research Institute | Convergent synthesis of combinatorial library |
Non-Patent Citations (4)
Title |
---|
BOGER D L ET AL: "Higher order iminodiacetic acid libraries for probing protein-protein interactions.", BIOORGANIC & MEDICINAL CHEMISTRY. AUG 1998, vol. 6, no. 8, August 1998 (1998-08-01), pages 1347 - 1378, XP002369171, ISSN: 0968-0896 * |
BOGER D L ET AL: "Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin.alpha.V.beta.3", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 123, no. 7, 2001, pages 1280 - 1288, XP002215423, ISSN: 0002-7863 * |
DATABASE CAPLUS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002369179, retrieved from STN accession no. 1998:550559 Database accession no. 129:189127 * |
See also references of WO0172297A1 * |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20021025 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20021025;LT PAYMENT 20021025;LV PAYMENT 20021025;MK PAYMENT 20021025;RO PAYMENT 20021025;SI PAYMENT 20021025 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07C 261/00 20060101AFI20060227BHEP Ipc: A61K 38/00 20060101ALI20060227BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060317 |
|
17Q | First examination report despatched |
Effective date: 20061002 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Effective date: 20110114 |