EP1232247A4 - Modulation of signal transduction - Google Patents

Modulation of signal transduction

Info

Publication number
EP1232247A4
EP1232247A4 EP00991029A EP00991029A EP1232247A4 EP 1232247 A4 EP1232247 A4 EP 1232247A4 EP 00991029 A EP00991029 A EP 00991029A EP 00991029 A EP00991029 A EP 00991029A EP 1232247 A4 EP1232247 A4 EP 1232247A4
Authority
EP
European Patent Office
Prior art keywords
modulation
signal transduction
transduction
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00991029A
Other languages
German (de)
French (fr)
Other versions
EP1232247A2 (en
Inventor
Gerhart Graupner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Graupner Gerhart
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1232247A2 publication Critical patent/EP1232247A2/en
Publication of EP1232247A4 publication Critical patent/EP1232247A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
EP00991029A 1999-11-23 2000-11-22 Modulation of signal transduction Withdrawn EP1232247A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16743899P 1999-11-23 1999-11-23
US167438P 1999-11-23
PCT/US2000/042233 WO2001038344A2 (en) 1999-11-23 2000-11-22 Modulation of signal transduction

Publications (2)

Publication Number Publication Date
EP1232247A2 EP1232247A2 (en) 2002-08-21
EP1232247A4 true EP1232247A4 (en) 2003-06-18

Family

ID=22607380

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00991029A Withdrawn EP1232247A4 (en) 1999-11-23 2000-11-22 Modulation of signal transduction

Country Status (5)

Country Link
EP (1) EP1232247A4 (en)
JP (1) JP2003518017A (en)
AU (1) AU3082901A (en)
CA (1) CA2392453C (en)
WO (1) WO2001038344A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG140607A1 (en) 2004-06-23 2008-03-28 Sirion Therapeutics Inc Methods and compositions for treating ophthalmic conditions with retinyl derivatives
US7432307B2 (en) 2004-11-04 2008-10-07 Sirion Therapeutics, Inc. Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation
CN102240278A (en) * 2004-12-08 2011-11-16 矫正诊疗公司 Methods, assays and compositions for treating retinol-related diseases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO0138344A3 *
SUCOV H M ET AL: "RETINOIC ACID AND RETINOIC ACID RECEPTORS IN DEVELOPMENT", MOLECULAR NEUROBIOLOGY, HUMANA PRESS, US, vol. 10, no. 2/3, 1995, pages 169 - 184, XP002949771, ISSN: 0893-7648 *

Also Published As

Publication number Publication date
WO2001038344A2 (en) 2001-05-31
EP1232247A2 (en) 2002-08-21
JP2003518017A (en) 2003-06-03
AU3082901A (en) 2001-06-04
CA2392453C (en) 2012-03-20
CA2392453A1 (en) 2001-05-31
WO2001038344A3 (en) 2002-01-10

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