EP1232247A4 - Modulation of signal transduction - Google Patents
Modulation of signal transductionInfo
- Publication number
- EP1232247A4 EP1232247A4 EP00991029A EP00991029A EP1232247A4 EP 1232247 A4 EP1232247 A4 EP 1232247A4 EP 00991029 A EP00991029 A EP 00991029A EP 00991029 A EP00991029 A EP 00991029A EP 1232247 A4 EP1232247 A4 EP 1232247A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- modulation
- signal transduction
- transduction
- signal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000019491 signal transduction Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16743899P | 1999-11-23 | 1999-11-23 | |
US167438P | 1999-11-23 | ||
PCT/US2000/042233 WO2001038344A2 (en) | 1999-11-23 | 2000-11-22 | Modulation of signal transduction |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1232247A2 EP1232247A2 (en) | 2002-08-21 |
EP1232247A4 true EP1232247A4 (en) | 2003-06-18 |
Family
ID=22607380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00991029A Withdrawn EP1232247A4 (en) | 1999-11-23 | 2000-11-22 | Modulation of signal transduction |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1232247A4 (en) |
JP (1) | JP2003518017A (en) |
AU (1) | AU3082901A (en) |
CA (1) | CA2392453C (en) |
WO (1) | WO2001038344A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG140607A1 (en) | 2004-06-23 | 2008-03-28 | Sirion Therapeutics Inc | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
US7432307B2 (en) | 2004-11-04 | 2008-10-07 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation |
CN102240278A (en) * | 2004-12-08 | 2011-11-16 | 矫正诊疗公司 | Methods, assays and compositions for treating retinol-related diseases |
-
2000
- 2000-11-22 EP EP00991029A patent/EP1232247A4/en not_active Withdrawn
- 2000-11-22 WO PCT/US2000/042233 patent/WO2001038344A2/en active Application Filing
- 2000-11-22 CA CA2392453A patent/CA2392453C/en not_active Expired - Lifetime
- 2000-11-22 AU AU30829/01A patent/AU3082901A/en not_active Abandoned
- 2000-11-22 JP JP2001540107A patent/JP2003518017A/en active Pending
Non-Patent Citations (2)
Title |
---|
See also references of WO0138344A3 * |
SUCOV H M ET AL: "RETINOIC ACID AND RETINOIC ACID RECEPTORS IN DEVELOPMENT", MOLECULAR NEUROBIOLOGY, HUMANA PRESS, US, vol. 10, no. 2/3, 1995, pages 169 - 184, XP002949771, ISSN: 0893-7648 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001038344A2 (en) | 2001-05-31 |
EP1232247A2 (en) | 2002-08-21 |
JP2003518017A (en) | 2003-06-03 |
AU3082901A (en) | 2001-06-04 |
CA2392453C (en) | 2012-03-20 |
CA2392453A1 (en) | 2001-05-31 |
WO2001038344A3 (en) | 2002-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020617 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030506 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 31/203 B Ipc: 7C 12N 5/06 A Ipc: 7A 61K 31/07 B |
|
17Q | First examination report despatched |
Effective date: 20080716 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: GRAUPNER, GERHART |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: GRAUPNER, GERHART |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20130601 |