EP1223962A4 - Method and compositions for inhibiting adhesion formation - Google Patents
Method and compositions for inhibiting adhesion formationInfo
- Publication number
- EP1223962A4 EP1223962A4 EP00970476A EP00970476A EP1223962A4 EP 1223962 A4 EP1223962 A4 EP 1223962A4 EP 00970476 A EP00970476 A EP 00970476A EP 00970476 A EP00970476 A EP 00970476A EP 1223962 A4 EP1223962 A4 EP 1223962A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- adhesion formation
- inhibiting adhesion
- inhibiting
- formation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/045—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/424—Anti-adhesion agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/432—Inhibitors, antagonists
- A61L2300/436—Inhibitors, antagonists of receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US405522 | 1973-10-11 | ||
US40552299A | 1999-09-23 | 1999-09-23 | |
PCT/US2000/026095 WO2001021196A1 (en) | 1999-09-23 | 2000-09-22 | Method and compositions for inhibiting adhesion formation |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1223962A1 EP1223962A1 (en) | 2002-07-24 |
EP1223962A4 true EP1223962A4 (en) | 2004-01-21 |
Family
ID=23604048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00970476A Withdrawn EP1223962A4 (en) | 1999-09-23 | 2000-09-22 | Method and compositions for inhibiting adhesion formation |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1223962A4 (en) |
JP (1) | JP2003509468A (en) |
KR (1) | KR20020048941A (en) |
CN (1) | CN1399554A (en) |
AU (1) | AU781442B2 (en) |
BR (1) | BR0014222A (en) |
CA (1) | CA2384812A1 (en) |
MX (1) | MXPA02003079A (en) |
WO (1) | WO2001021196A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2025685B1 (en) * | 2007-08-15 | 2013-06-19 | Canadian Blood Services | Monoclonal antibodies against BETA3 integrins |
EP3485921A4 (en) | 2016-07-13 | 2020-03-11 | Mochida Pharmaceutical Co., Ltd. | Adhesion-preventing composition |
WO2019138583A1 (en) * | 2018-01-15 | 2019-07-18 | 持田製薬株式会社 | Anti-adhesion composition |
KR102318958B1 (en) * | 2019-08-08 | 2021-10-27 | 고려대학교 산학협력단 | Pharmaceutical Composition for Preventing or Treating Tissue Adhesion Comprising Integrin α2β1 Inhibitors |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014103A1 (en) * | 1989-05-17 | 1990-11-29 | Scripps Clinic And Research Foundation | Polypeptide-antibody conjugate for inhibiting cell adhesion |
US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
WO1999009982A1 (en) * | 1997-08-25 | 1999-03-04 | Harold Brem | Prevention of adhesions and excessive scar formation using angiogenesis inhibitors |
-
2000
- 2000-09-22 AU AU79850/00A patent/AU781442B2/en not_active Ceased
- 2000-09-22 WO PCT/US2000/026095 patent/WO2001021196A1/en active IP Right Grant
- 2000-09-22 BR BR0014222-0A patent/BR0014222A/en not_active IP Right Cessation
- 2000-09-22 KR KR1020027003796A patent/KR20020048941A/en not_active Application Discontinuation
- 2000-09-22 EP EP00970476A patent/EP1223962A4/en not_active Withdrawn
- 2000-09-22 CA CA002384812A patent/CA2384812A1/en not_active Abandoned
- 2000-09-22 JP JP2001524620A patent/JP2003509468A/en active Pending
- 2000-09-22 MX MXPA02003079A patent/MXPA02003079A/en unknown
- 2000-09-22 CN CN00816148A patent/CN1399554A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014103A1 (en) * | 1989-05-17 | 1990-11-29 | Scripps Clinic And Research Foundation | Polypeptide-antibody conjugate for inhibiting cell adhesion |
US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
WO1999009982A1 (en) * | 1997-08-25 | 1999-03-04 | Harold Brem | Prevention of adhesions and excessive scar formation using angiogenesis inhibitors |
Non-Patent Citations (2)
Title |
---|
PIRISI A: "Postsurgical adhesions reduced with antibody", LANCET (NORTH AMERICAN EDITION), vol. 354, no. 9185, 2 October 1999 (1999-10-02), pages 1184, XP001156012, ISSN: 0099-5355 * |
See also references of WO0121196A1 * |
Also Published As
Publication number | Publication date |
---|---|
MXPA02003079A (en) | 2004-04-21 |
EP1223962A1 (en) | 2002-07-24 |
KR20020048941A (en) | 2002-06-24 |
AU7985000A (en) | 2001-04-24 |
CN1399554A (en) | 2003-02-26 |
JP2003509468A (en) | 2003-03-11 |
WO2001021196A1 (en) | 2001-03-29 |
BR0014222A (en) | 2003-02-25 |
AU781442B2 (en) | 2005-05-26 |
CA2384812A1 (en) | 2001-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020418 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20020418;LT PAYMENT 20020418;LV PAYMENT 20020418;MK PAYMENT 20020418;RO PAYMENT 20020418;SI PAYMENT 20020418 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20031209 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61P 41/00 B Ipc: 7C 07K 16/28 A Ipc: 7A 61K 39/395 B |
|
17Q | First examination report despatched |
Effective date: 20040527 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
RTI1 | Title (correction) |
Free format text: MONOCLONAL ANTIBODY LM 609 FOR INHIBITING POST-OPERATIVE ADHESION FORMATION |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20101216 |