EP1173477A4 - 49 proteines humaines secretees - Google Patents

49 proteines humaines secretees

Info

Publication number
EP1173477A4
EP1173477A4 EP00920165A EP00920165A EP1173477A4 EP 1173477 A4 EP1173477 A4 EP 1173477A4 EP 00920165 A EP00920165 A EP 00920165A EP 00920165 A EP00920165 A EP 00920165A EP 1173477 A4 EP1173477 A4 EP 1173477A4
Authority
EP
European Patent Office
Prior art keywords
secreted proteins
human secreted
human
proteins
secreted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00920165A
Other languages
German (de)
English (en)
Other versions
EP1173477A1 (fr
Inventor
Craig A Rosen
Steven M Ruben
George Komatsoulis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP1173477A1 publication Critical patent/EP1173477A1/fr
Publication of EP1173477A4 publication Critical patent/EP1173477A4/fr
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Addiction (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
EP00920165A 1999-04-09 2000-04-06 49 proteines humaines secretees Withdrawn EP1173477A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12870299P 1999-04-09 1999-04-09
US128702P 1999-04-09
US17704900P 2000-01-20 2000-01-20
US177049P 2000-01-20
PCT/US2000/009069 WO2000061620A1 (fr) 1999-04-09 2000-04-06 49 proteines humaines secretees

Publications (2)

Publication Number Publication Date
EP1173477A1 EP1173477A1 (fr) 2002-01-23
EP1173477A4 true EP1173477A4 (fr) 2003-02-26

Family

ID=26826865

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00920165A Withdrawn EP1173477A4 (fr) 1999-04-09 2000-04-06 49 proteines humaines secretees

Country Status (5)

Country Link
EP (1) EP1173477A4 (fr)
JP (1) JP2003501009A (fr)
AU (1) AU4074500A (fr)
CA (1) CA2370767A1 (fr)
WO (1) WO2000061620A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034135B2 (en) 2000-05-03 2006-04-25 Millennium Pharmaceuticals, Inc. Molecules of the NBS/LRR protein family and uses thereof
WO2001083753A2 (fr) * 2000-05-03 2001-11-08 Millennium Pharmaceuticals, Inc. Nouvelles molecules appartenant a la famille de proteines nbs/lrr et utilisations de ces dernieres
MX2007002043A (es) 2004-08-16 2007-10-11 Quark Biotech Inc Usos terapeuticos de los inhibidores del rtp801.
UY30097A1 (es) 2006-01-20 2007-08-31 Atugen Ag Usos terapeuticos de inhibidores de rtp801
US7825099B2 (en) 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
GB2450840B (en) 2006-05-11 2010-12-29 Quark Pharmaceuticals Inc Screening Systems Utilizing RTP801
WO2007141796A2 (fr) 2006-06-09 2007-12-13 Quark Pharmaceuticals, Inc. Utilisations thérapeutiques d'inhibiteurs de rtp801l
JP2010518880A (ja) 2007-02-26 2010-06-03 クアーク・ファーマスーティカルス、インコーポレイテッド Rtp801のインヒビター及びその疾患の治療における使用
US8614311B2 (en) 2007-12-12 2013-12-24 Quark Pharmaceuticals, Inc. RTP801L siRNA compounds and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1997007198A2 (fr) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Sequences d'adn et proteines secretees codees par celles-ci
WO1998032853A2 (fr) * 1997-01-24 1998-07-30 Genetics Institute, Inc. Proteines secretees et polynucleotides les codant
WO1999011668A1 (fr) * 1997-09-03 1999-03-11 The University Of Mississippi Medical Center Molecules d'adn codant des polypeptides receptifs a l'imidazoline et polypeptides codes par cet adn

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2283299A1 (fr) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 nouvelles proteines secretees

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
WO1997007198A2 (fr) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Sequences d'adn et proteines secretees codees par celles-ci
WO1998032853A2 (fr) * 1997-01-24 1998-07-30 Genetics Institute, Inc. Proteines secretees et polynucleotides les codant
WO1999011668A1 (fr) * 1997-09-03 1999-03-11 The University Of Mississippi Medical Center Molecules d'adn codant des polypeptides receptifs a l'imidazoline et polypeptides codes par cet adn

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 19 January 1999 (1999-01-19), BEDNARIK ET AL.: "Human secreted protein gene 163 clone HAFAL73", XP002213346, Database accession no. AAV59673 *
JACOBS K A ET AL: "A GENETIC SELECTION FOR ISOLATING CDNAS ENCODING SECRETED PROTEINS", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 198, 1 October 1997 (1997-10-01), pages 289 - 296, XP002045919, ISSN: 0378-1119 *
KLEIN R D ET AL: "SELECTION FOR GENES ENCODING SECRETED PROTEINS AND RECEPTORS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 14, 9 July 1996 (1996-07-09), pages 7108 - 7113, XP002061411, ISSN: 0027-8424 *
See also references of WO0061620A1 *

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CA2370767A1 (fr) 2000-10-19
EP1173477A1 (fr) 2002-01-23
WO2000061620A1 (fr) 2000-10-19

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