EP1161237A4 - Inhibiteurs de protease - Google Patents

Inhibiteurs de protease

Info

Publication number
EP1161237A4
EP1161237A4 EP00917997A EP00917997A EP1161237A4 EP 1161237 A4 EP1161237 A4 EP 1161237A4 EP 00917997 A EP00917997 A EP 00917997A EP 00917997 A EP00917997 A EP 00917997A EP 1161237 A4 EP1161237 A4 EP 1161237A4
Authority
EP
European Patent Office
Prior art keywords
protease inhibitors
protease
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00917997A
Other languages
German (de)
English (en)
Other versions
EP1161237A1 (fr
Inventor
Scott Kevin Thompson
Daniel Frank Veber
Stacie Marie Halbert
Sirishkumar Nidamarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1161237A1 publication Critical patent/EP1161237A1/fr
Publication of EP1161237A4 publication Critical patent/EP1161237A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/04—Seven-membered rings not condensed with other rings
    • C07D321/06—1,3-Dioxepines; Hydrogenated 1,3-dioxepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP00917997A 1999-03-16 2000-03-16 Inhibiteurs de protease Withdrawn EP1161237A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12465999P 1999-03-16 1999-03-16
US124659P 1999-03-16
PCT/US2000/006888 WO2000054769A1 (fr) 1999-03-16 2000-03-16 Inhibiteurs de protease

Publications (2)

Publication Number Publication Date
EP1161237A1 EP1161237A1 (fr) 2001-12-12
EP1161237A4 true EP1161237A4 (fr) 2002-03-27

Family

ID=22416114

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00917997A Withdrawn EP1161237A4 (fr) 1999-03-16 2000-03-16 Inhibiteurs de protease

Country Status (9)

Country Link
EP (1) EP1161237A4 (fr)
JP (1) JP2002539160A (fr)
AR (1) AR022927A1 (fr)
AU (1) AU3888200A (fr)
CO (1) CO5180542A1 (fr)
HK (1) HK1043534A1 (fr)
PE (1) PE20001564A1 (fr)
UY (1) UY26026A1 (fr)
WO (1) WO2000054769A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
EP1232155A4 (fr) 1999-11-10 2002-11-20 Smithkline Beecham Corp Inhibiteurs de protease
WO2001034600A1 (fr) 1999-11-10 2001-05-17 Smithkline Beecham Corporation Inhibiteurs de protease
JP2003513924A (ja) 1999-11-10 2003-04-15 スミスクライン・ビーチャム・コーポレイション プロテア−ゼ阻害剤
SK13632002A3 (sk) 2000-03-21 2003-02-04 Smithkline Beecham Corporation C1-6-alkyl-4-amino-azepán-3-ónové zlúčeniny, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom, ich použitie a medziprodukty
US7282512B2 (en) 2002-01-17 2007-10-16 Smithkline Beecham Corporation Cycloalkyl ketoamides derivatives useful as cathepsin K inhibitors
JP2004196696A (ja) * 2002-12-18 2004-07-15 Kyowa Hakko Kogyo Co Ltd 関節炎の予防剤または治療剤
CN103649072A (zh) * 2011-05-27 2014-03-19 莱西肯医药有限公司 基于4h-噻吩并[3,2-c]色烯的背板胶质乙酰酯酶抑制剂及其用法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004172A1 (fr) * 1992-08-20 1994-03-03 Prototek, Inc. Inhibiteurs cetoniques actives par peptidyle et contenant des sequences peptidiques naturelles et non naturelles
EP0603769A1 (fr) * 1992-12-25 1994-06-29 Mitsubishi Chemical Corporation Dérivés d'alpha-aminocétones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004172A1 (fr) * 1992-08-20 1994-03-03 Prototek, Inc. Inhibiteurs cetoniques actives par peptidyle et contenant des sequences peptidiques naturelles et non naturelles
EP0603769A1 (fr) * 1992-12-25 1994-06-29 Mitsubishi Chemical Corporation Dérivés d'alpha-aminocétones

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0054769A1 *

Also Published As

Publication number Publication date
WO2000054769A1 (fr) 2000-09-21
AR022927A1 (es) 2002-09-04
EP1161237A1 (fr) 2001-12-12
PE20001564A1 (es) 2001-02-08
UY26026A1 (es) 2000-10-31
HK1043534A1 (zh) 2002-09-20
JP2002539160A (ja) 2002-11-19
CO5180542A1 (es) 2002-07-30
AU3888200A (en) 2000-10-04

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