EP1150942A4 - Improved compounds for protein binding - Google Patents

Improved compounds for protein binding

Info

Publication number
EP1150942A4
EP1150942A4 EP00904701A EP00904701A EP1150942A4 EP 1150942 A4 EP1150942 A4 EP 1150942A4 EP 00904701 A EP00904701 A EP 00904701A EP 00904701 A EP00904701 A EP 00904701A EP 1150942 A4 EP1150942 A4 EP 1150942A4
Authority
EP
European Patent Office
Prior art keywords
protein binding
improved compounds
compounds
improved
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00904701A
Other languages
German (de)
French (fr)
Other versions
EP1150942A1 (en
Inventor
Ping Yin
Christopher John Burns
Matthew Peter Wilkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ambri Ltd
Original Assignee
Ambri Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambri Ltd filed Critical Ambri Ltd
Publication of EP1150942A1 publication Critical patent/EP1150942A1/en
Publication of EP1150942A4 publication Critical patent/EP1150942A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EP00904701A 1999-02-08 2000-02-08 Improved compounds for protein binding Withdrawn EP1150942A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP856399 1999-02-08
AUPP8563A AUPP856399A0 (en) 1999-02-08 1999-02-08 Improved compounds for protein binding
PCT/AU2000/000075 WO2000047548A1 (en) 1999-02-08 2000-02-08 Improved compounds for protein binding

Publications (2)

Publication Number Publication Date
EP1150942A1 EP1150942A1 (en) 2001-11-07
EP1150942A4 true EP1150942A4 (en) 2003-02-12

Family

ID=3812765

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00904701A Withdrawn EP1150942A4 (en) 1999-02-08 2000-02-08 Improved compounds for protein binding

Country Status (6)

Country Link
EP (1) EP1150942A4 (en)
JP (1) JP2002536428A (en)
CN (1) CN1345301A (en)
AU (1) AUPP856399A0 (en)
CA (1) CA2341348A1 (en)
WO (1) WO2000047548A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002367810A1 (en) * 2002-03-28 2003-11-10 Rutgers, The State Of University Of New Jersey Bis-transition-metal-chelate-probes
US6919333B2 (en) * 2002-11-12 2005-07-19 Rutgers, The State University Of New Jersey Bis-transition-metal-chelate probes
DE10227599B4 (en) * 2002-06-20 2005-04-28 Proteome Factory Ag Method and reagent for the specific identification and quantification of one or more proteins in a sample
AU2004254295B2 (en) * 2003-07-08 2010-05-27 Tacnia Pty Ltd Improvements in sensor chips
AU2003903504A0 (en) 2003-07-08 2003-07-24 Johnson, Daniel Improvements in sensor chips
JP4970035B2 (en) * 2003-08-21 2012-07-04 リポテック・プロプライエタリー・リミテッド Targeting dendritic cells in vivo
US7371585B2 (en) 2003-12-31 2008-05-13 Genencor International, Inc. Membranes incorporating recognition moieties
DE102004038134B4 (en) * 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalent chelators for modifying and organizing target molecules, methods for their preparation and their use
JP2008508333A (en) * 2004-08-05 2008-03-21 ヨハン ウォルフガング ゲーテ−ウニベルジテート フランクフルト アム マイン Multivalent chelators for modification and organization of target molecules
EP2015071A1 (en) 2007-07-13 2009-01-14 FUJIFILM Corporation Carrier, process for producing same, bioreactor, and chip for surface plasmon resonance analysis
US8137733B2 (en) 2007-11-22 2012-03-20 Fujifilm Corporation Process for producing a carrier
JP2010190891A (en) * 2009-01-22 2010-09-02 Fujifilm Corp Carrier, method of manufacturing the same, and extraction operation instrument
DE102010008417A1 (en) * 2010-02-18 2011-08-18 Johann Wolfgang Goethe-Universität Frankfurt am Main, 60323 High affinity multivalent chelator compounds (MCHs) and their use for the structural and functional analysis of target molecules
WO2013160453A2 (en) * 2012-04-26 2013-10-31 Iba Gmbh Adapter molecule capable of reversibly equipping a fusion protein carrying an oligohistidine affinity tag with a further affinity tag and methods of using the same
US10557852B2 (en) * 2014-04-29 2020-02-11 Yeda Research And Development Co. Ltd. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof
US11639929B2 (en) * 2014-04-29 2023-05-02 Yeda Research And Development Co. Ltd. Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors
CN110183672B (en) * 2019-05-31 2021-07-09 天津大学 PETX polymer, preparation method and three-dimensional thorn-shaped sensor interface
CN116970027A (en) * 2020-11-04 2023-10-31 中国药科大学 Dumbbell amphiphilic peptide dendrimer, synthesis and application thereof as drug delivery system

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3158635A (en) * 1959-03-18 1964-11-24 Stauffer Chemical Co Bis-adduction products and methods of preparing same
US3700671A (en) * 1967-05-15 1972-10-24 Monacelli Walter J Chelating compositions
EP0243929A2 (en) * 1986-04-30 1987-11-04 Robin Ewart Offord Polypeptide and protein derivatives and process for their preparation
US5096946A (en) * 1989-08-18 1992-03-17 Rainer Norman B Polymer product for the selective absorption of dissolved ions
US5342604A (en) * 1988-10-31 1994-08-30 The Dow Chemical Company Complexes possessing ortho ligating functionality
WO1996003646A1 (en) * 1994-07-22 1996-02-08 Akzo Nobel N.V. Chelator idac-2 and method for purifying chelator conjugated compounds
DE19505960A1 (en) * 1995-02-21 1996-08-22 Deutsches Krebsforsch Conjugate for the individual dosage of drugs
DE19518421A1 (en) * 1995-05-19 1996-11-21 Basf Ag Aspartic acid oligomers and derivs. with high chelating capacity
WO1999066780A2 (en) * 1998-06-25 1999-12-29 Smithkline Beecham Plc Cinoxacin lanthanide chelates and their use as biomolecular probes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462454B (en) * 1988-11-10 1990-06-25 Pharmacia Ab METHOD FOR USE IN BIOSENSORS
US5580527A (en) * 1992-05-18 1996-12-03 Moltech Corporation Polymeric luminophores for sensing of oxygen
DE4430023A1 (en) * 1994-08-24 1996-02-29 Boehringer Mannheim Gmbh Electrochemical sensor
DE4433980C2 (en) * 1994-09-23 1996-08-22 Boehringer Ingelheim Int Process and biosensor hit for investigating the interaction of biomolecules by means of surface plasma resonance
US5620850A (en) * 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
AU699321B2 (en) * 1995-04-07 1998-12-03 Mogens Havsteen Jacobsen Method of photochemical immobilization of ligands using quinones
DE19607279A1 (en) * 1996-02-27 1997-08-28 Bayer Ag Membrane biosensors supported by solid bodies
WO1998000435A2 (en) * 1996-07-03 1998-01-08 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3158635A (en) * 1959-03-18 1964-11-24 Stauffer Chemical Co Bis-adduction products and methods of preparing same
US3700671A (en) * 1967-05-15 1972-10-24 Monacelli Walter J Chelating compositions
EP0243929A2 (en) * 1986-04-30 1987-11-04 Robin Ewart Offord Polypeptide and protein derivatives and process for their preparation
US5342604A (en) * 1988-10-31 1994-08-30 The Dow Chemical Company Complexes possessing ortho ligating functionality
US5096946A (en) * 1989-08-18 1992-03-17 Rainer Norman B Polymer product for the selective absorption of dissolved ions
WO1996003646A1 (en) * 1994-07-22 1996-02-08 Akzo Nobel N.V. Chelator idac-2 and method for purifying chelator conjugated compounds
DE19505960A1 (en) * 1995-02-21 1996-08-22 Deutsches Krebsforsch Conjugate for the individual dosage of drugs
DE19518421A1 (en) * 1995-05-19 1996-11-21 Basf Ag Aspartic acid oligomers and derivs. with high chelating capacity
WO1999066780A2 (en) * 1998-06-25 1999-12-29 Smithkline Beecham Plc Cinoxacin lanthanide chelates and their use as biomolecular probes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
HOCHULI E ET AL: "NEW METAL CHELATE ADSORBENT SELECTIVE FOR PROTEINS AND PEPTIDES CONTAINING NEIGHBOURING HISTIDINE RESIDUES", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 411, 1987, pages 177 - 184, XP002059738, ISSN: 0021-9673 *
MICHAELIS, L. ET AL., J. BIOL. CHEM., vol. 106, 1934, pages 331 - 341, XP001040686 *
See also references of WO0047548A1 *
TERCERO-MORENO, J.M. ET AL., J. COORD. CHEM., vol. 35, 1995, pages 73 - 83, XP001040664 *
YASHUNSKII V G ET AL: "SYNTHESIS, ACID-BASE CHARACTERISTICS, AND COMPLEX-FORMING PROPERTIES OF ÄÄ(2-HYDROXYTRIMETHYLENE)DINITRILOÜTETRAKIS(ETHYLENEDINITRILLO)Ü-O CTAACETIC ACID", JOURNAL OF GENERAL CHEMISTRY USSR, CONSULTANTS BUREAU. NEW YORK, US, vol. 60, no. 2, 1990, pages 309 - 313, XP001109160 *

Also Published As

Publication number Publication date
WO2000047548A1 (en) 2000-08-17
EP1150942A1 (en) 2001-11-07
CA2341348A1 (en) 2000-08-17
AUPP856399A0 (en) 1999-03-04
CN1345301A (en) 2002-04-17
JP2002536428A (en) 2002-10-29

Similar Documents

Publication Publication Date Title
EP1203026A4 (en) Binding moieties for fibrin
GB2357761B (en) Compounds
EP1150942A4 (en) Improved compounds for protein binding
GB9921125D0 (en) Proteins
GB2375735B (en) Binding apparatus
GB9928950D0 (en) Binding protein
EP1368654A4 (en) Multiplex protein interaction determinations using glutathione-gst binding
GB9903430D0 (en) Novel proteins
GB9927681D0 (en) Protein
TW399517U (en) Stapler
GB9818124D0 (en) CD28 binding protein
IL150134A0 (en) Apoptin-associating protein
EP1146053A4 (en) Meg-4 protein
GB0112374D0 (en) Novel protein
EP1209231A4 (en) Meg-1 protein
HU2208U (en) Binding
EG22315A (en) Binding element
HU0000470D0 (en) Binding material
GB9909578D0 (en) Immunoglobulin binding protein
GB9924060D0 (en) VIP54 protein
EP1188828A4 (en) Reg-binding protein
EP1235840A4 (en) Methods for identifying compounds that affect rna/rna binding protein interactions
GB9923421D0 (en) Binding agents
GB9923337D0 (en) Binding agents
GB9925990D0 (en) Binding assays

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010816

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL PAYMENT 20010815;LT PAYMENT 20010815;LV PAYMENT 20010815;MK PAYMENT 20010815;RO PAYMENT 20010815;SI PAYMENT 20010815

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INS

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AMBRI LIMITED

A4 Supplementary search report drawn up and despatched

Effective date: 20030103

111L Licence recorded

Free format text: 0100 BIOSENSOR ENTREPRISES , LLC

Effective date: 20030825

17Q First examination report despatched

Effective date: 20040312

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050901