EP1146887A4 - Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same - Google Patents

Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same

Info

Publication number: EP1146887A4
Authority: EP; European Patent Office
Prior art keywords: same; desmethylvancosamine; residue; methods; combinatorial libraries
Prior art date: 1999-01-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00903240A

Other languages

German (de)

French (fr)

Other versions

EP1146887A1 (en

Inventor

Daniel Kahne

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Princeton University

Original Assignee

Princeton University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-12

Filing date

2000-01-12

Publication date

2003-05-07

2000-01-12 Application filed by Princeton University filed Critical Princeton University

2001-10-24 Publication of EP1146887A1 publication Critical patent/EP1146887A1/en

2003-05-07 Publication of EP1146887A4 publication Critical patent/EP1146887A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP00903240A 1999-01-12 2000-01-12 Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same Withdrawn EP1146887A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11559499P	1999-01-12	1999-01-12
US115594P		1999-01-12
PCT/US2000/000650 WO2000041710A1 (en)	1999-01-12	2000-01-12	Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same

Publications (2)

Publication Number	Publication Date
EP1146887A1 EP1146887A1 (en)	2001-10-24
EP1146887A4 true EP1146887A4 (en)	2003-05-07

Family

ID=22362330

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00903240A Withdrawn EP1146887A4 (en)	1999-01-12	2000-01-12	Glycopeptide antibiotics containing a desmethylvancosamine residue, combinatorial libraries of same and methods of producing same

Country Status (3)

Country	Link
EP (1)	EP1146887A4 (en)
AU (1)	AU2501700A (en)
WO (1)	WO2000041710A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2337103A1 (en) *	1998-07-14	2000-01-27	Robert Kerns	Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CA2372392A1 (en) *	1999-05-19	2000-11-23	Min Ge	Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CN101959900A (en) *	2007-12-26	2011-01-26	盐野义制药株式会社	Glycosylated glycopeptide antibiotic derivative
LT3244920T (en) *	2015-01-16	2023-08-25	Zoetis Services Llc	Foot-and-mouth disease vaccine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4742045A (en) *	1986-07-30	1988-05-03	Smithkline Beckman Corporation	Glycopeptide antibiotics
US4882313A (en) *	1987-07-31	1989-11-21	Smithkline Beckman Corporation	Carboxamide derivatives of glycopeptides
DE4013077A1 (en) *	1990-04-25	1991-10-31	Hoechst Ag	METHOD FOR GLYCOSIDASE-CATALYZED SYNTHESIS OF GLYCO-CONJUGATES

2000
- 2000-01-12 EP EP00903240A patent/EP1146887A4/en not_active Withdrawn
- 2000-01-12 WO PCT/US2000/000650 patent/WO2000041710A1/en not_active Application Discontinuation
- 2000-01-12 AU AU25017/00A patent/AU2501700A/en not_active Abandoned

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MALABARBA A ET AL: "STRUCTURAL MODIFICATIONS OF GLYCOPEPTIDE ANTIBIOTICS", MEDICINAL RESEARCH REVIEWS, NEW YORK, NY, US, vol. 17, no. 1, 1997, pages 69 - 137, XP000985926, ISSN: 0198-6325 *
MALABARBA A NICAS TI CIABATTI R: "Glycopeptide resistance in multiple antibiotic-resistant Gram-positive bacteria: a current challenge for novel semi-synthetic glycopeptide derivatives", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 32, no. 6, 1 June 1997 (1997-06-01), pages 459 - 478, XP004088458, ISSN: 0223-5234 *
See also references of WO0041710A1 *

Also Published As

Publication number	Publication date
EP1146887A1 (en)	2001-10-24
AU2501700A (en)	2000-08-01
WO2000041710A9 (en)	2001-11-22
WO2000041710A1 (en)	2000-07-20

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Legal Events

Date	Code	Title	Description
2001-09-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-10-24	17P	Request for examination filed	Effective date: 20010809
2001-10-24	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2001-10-24	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2003-05-07	A4	Supplementary search report drawn up and despatched	Effective date: 20030320
2003-05-07	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 38/00 B Ipc: 7C 07K 9/00 A Ipc: 7A 61K 38/04 B Ipc: 7A 61K 38/14 B Ipc: 7A 61K 38/12 B
2004-12-17	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2005-02-02	18D	Application deemed to be withdrawn	Effective date: 20040803