EP1141382A4 - Prokaryotisches system zum überwachen von proteaseaktivitäten - Google Patents
Prokaryotisches system zum überwachen von proteaseaktivitätenInfo
- Publication number
- EP1141382A4 EP1141382A4 EP00908220A EP00908220A EP1141382A4 EP 1141382 A4 EP1141382 A4 EP 1141382A4 EP 00908220 A EP00908220 A EP 00908220A EP 00908220 A EP00908220 A EP 00908220A EP 1141382 A4 EP1141382 A4 EP 1141382A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- protease activity
- system designed
- prokaryotic system
- monitor protease
- monitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11527099P | 1999-01-08 | 1999-01-08 | |
US115270P | 1999-01-08 | ||
PCT/US2000/000308 WO2000040745A1 (en) | 1999-01-08 | 2000-01-06 | Prokaryotic system designed to monitor protease activity |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1141382A1 EP1141382A1 (de) | 2001-10-10 |
EP1141382A4 true EP1141382A4 (de) | 2003-01-08 |
Family
ID=22360285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00908220A Withdrawn EP1141382A4 (de) | 1999-01-08 | 2000-01-06 | Prokaryotisches system zum überwachen von proteaseaktivitäten |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1141382A4 (de) |
JP (1) | JP2002534095A (de) |
AU (1) | AU764132B2 (de) |
CA (1) | CA2360022A1 (de) |
WO (1) | WO2000040745A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000052140A1 (en) * | 1999-03-05 | 2000-09-08 | Glaxo Group Limited | Assays for inhibitors of ftsh |
US20040038375A1 (en) * | 2000-08-29 | 2004-02-26 | Pedersen Poul Eric | Method for screening highly active proteases and inhibitors |
PL378073A1 (pl) * | 2003-02-04 | 2006-02-20 | Kabushiki Kaisha Yakult Honsha | Inhibitor białka oporności raka piersi (BCRP) |
US20090029369A1 (en) * | 2005-09-27 | 2009-01-29 | Oncalis Ag | Genetic selection system to identify proteases, protease substrates and protease inhibitors |
US11384358B2 (en) | 2017-03-29 | 2022-07-12 | President And Fellows Of Harvard College | Method of regulating gene expression in a cell |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5599906A (en) * | 1990-04-13 | 1997-02-04 | Schering Corporation | Protease assays |
-
2000
- 2000-01-06 WO PCT/US2000/000308 patent/WO2000040745A1/en active Search and Examination
- 2000-01-06 CA CA002360022A patent/CA2360022A1/en not_active Abandoned
- 2000-01-06 AU AU29607/00A patent/AU764132B2/en not_active Ceased
- 2000-01-06 JP JP2000592438A patent/JP2002534095A/ja active Pending
- 2000-01-06 EP EP00908220A patent/EP1141382A4/de not_active Withdrawn
Non-Patent Citations (5)
Title |
---|
DASMAHAPATRA B ET AL: "A GENETIC SYSTEM FOR STUDYING THE ACTIVITY OF A PROTEOLYTIC ENZYME", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 89, May 1992 (1992-05-01), pages 4159 - 4162, XP000946643, ISSN: 0027-8424 * |
FIELDS S ET AL: "THE TWO-HYBRID SYSTEM: AN ASSAY FOR PROTEIN-PROTEIN INTERACTIONS", TRENDS IN GENETICS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 10, no. 8, 1 August 1994 (1994-08-01), pages 286 - 292, XP000647708, ISSN: 0168-9525 * |
LAWLER JOSEPH F JR ET AL: "Viral protease assay based on GAL4 inactivation is applicable to high-throughput screening in mammalian cells.", ANALYTICAL BIOCHEMISTRY, vol. 269, no. 1, 10 April 1999 (1999-04-10), pages 133 - 138, XP002220088, ISSN: 0003-2697 * |
LIEBIG H D ET AL: "PROTEINASE TRAPPING: SCREENING FOR VIRAL PROTEINASE MUTANTS BY ALPHA COMPLEMENTATION", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 88, no. 14, 15 July 1991 (1991-07-15), pages 5979 - 5983, XP000248161, ISSN: 0027-8424 * |
See also references of WO0040745A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1141382A1 (de) | 2001-10-10 |
CA2360022A1 (en) | 2000-07-13 |
AU764132B2 (en) | 2003-08-14 |
WO2000040745A1 (en) | 2000-07-13 |
JP2002534095A (ja) | 2002-10-15 |
AU2960700A (en) | 2000-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20010528 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: WITTEKIND, MICHAEL Inventor name: LACH, DAVID Inventor name: PATEL, PRAMATHESH |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021126 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20040830 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20050111 |