EP1073710A4 - Non-stochastic generation of genetic vaccines and enzymes - Google Patents
Non-stochastic generation of genetic vaccines and enzymesInfo
- Publication number
- EP1073710A4 EP1073710A4 EP00913378A EP00913378A EP1073710A4 EP 1073710 A4 EP1073710 A4 EP 1073710A4 EP 00913378 A EP00913378 A EP 00913378A EP 00913378 A EP00913378 A EP 00913378A EP 1073710 A4 EP1073710 A4 EP 1073710A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- enzymes
- stochastic generation
- genetic vaccines
- vaccines
- genetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000002068 genetic effect Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Ecology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11167668A EP2397549A3 (en) | 1999-02-04 | 2000-02-04 | Non-stochastic generation of genetic vaccines and enzymes |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US246178 | 1999-02-04 | ||
US09/246,178 US6171820B1 (en) | 1995-12-07 | 1999-02-04 | Saturation mutagenesis in directed evolution |
US09/267,118 US6238884B1 (en) | 1995-12-07 | 1999-03-09 | End selection in directed evolution |
US09/276,860 US6352842B1 (en) | 1995-12-07 | 1999-03-26 | Exonucease-mediated gene assembly in directed evolution |
US09/332,835 US6537776B1 (en) | 1999-06-14 | 1999-06-14 | Synthetic ligation reassembly in directed evolution |
PCT/US2000/003086 WO2000046344A2 (en) | 1999-02-04 | 2000-02-04 | Non-stochastic generation of genetic vaccines and enzymes |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1073710A3 EP1073710A3 (en) | 2000-12-28 |
EP1073710A2 EP1073710A2 (en) | 2001-02-07 |
EP1073710A4 true EP1073710A4 (en) | 2007-12-19 |
Family
ID=27500214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00913378A Ceased EP1073710A4 (en) | 1999-02-04 | 2000-02-04 | Non-stochastic generation of genetic vaccines and enzymes |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1073710A4 (en) |
IL (1) | IL138206A (en) |
MX (1) | MXPA00009723A (en) |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015581A1 (en) * | 1990-04-05 | 1991-10-17 | Roberto Crea | Walk-through mutagenesis |
WO1997020078A1 (en) * | 1995-11-30 | 1997-06-05 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
WO1998027230A1 (en) * | 1996-12-18 | 1998-06-25 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
WO1998032845A1 (en) * | 1997-01-24 | 1998-07-30 | Bioinvent International Ab | A method for in vitro molecular evolution of protein function |
WO1998042832A1 (en) * | 1997-03-25 | 1998-10-01 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
WO1999041368A2 (en) * | 1998-02-11 | 1999-08-19 | Maxygen, Inc. | Optimization of immunomodulatory properties of genetic vaccines |
WO2000053744A2 (en) * | 1999-03-09 | 2000-09-14 | Diversa Corporation | End selection in directed evolution |
WO2000058517A1 (en) * | 1999-03-26 | 2000-10-05 | Diversa Corporation | Exonuclease-mediated nucleic acid reassembly in directed evolution |
WO2000077262A1 (en) * | 1999-06-14 | 2000-12-21 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
-
2000
- 2000-02-04 EP EP00913378A patent/EP1073710A4/en not_active Ceased
- 2000-02-04 IL IL138206A patent/IL138206A/en not_active IP Right Cessation
- 2000-02-04 MX MXPA00009723A patent/MXPA00009723A/en active IP Right Grant
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015581A1 (en) * | 1990-04-05 | 1991-10-17 | Roberto Crea | Walk-through mutagenesis |
WO1997020078A1 (en) * | 1995-11-30 | 1997-06-05 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
WO1998027230A1 (en) * | 1996-12-18 | 1998-06-25 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
WO1998032845A1 (en) * | 1997-01-24 | 1998-07-30 | Bioinvent International Ab | A method for in vitro molecular evolution of protein function |
WO1998042832A1 (en) * | 1997-03-25 | 1998-10-01 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
WO1999041368A2 (en) * | 1998-02-11 | 1999-08-19 | Maxygen, Inc. | Optimization of immunomodulatory properties of genetic vaccines |
WO2000053744A2 (en) * | 1999-03-09 | 2000-09-14 | Diversa Corporation | End selection in directed evolution |
WO2000058517A1 (en) * | 1999-03-26 | 2000-10-05 | Diversa Corporation | Exonuclease-mediated nucleic acid reassembly in directed evolution |
WO2000077262A1 (en) * | 1999-06-14 | 2000-12-21 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
Non-Patent Citations (6)
Title |
---|
MARKS J D ET AL: "Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system", JOURNAL OF BIOLOGICAL CHEMISTRY 1992 UNITED STATES, vol. 267, no. 23, 1992, pages 16007 - 16010, XP002025816, ISSN: 0021-9258 * |
REIDHAAR-OLSON J F ET AL: "COMBINATORIAL CASSETTE MUTAGENESIS AS A PROBE OF THE INFORMATIONAL CONTENT OF PROTEIN SEQUENCES", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 241, 1 July 1988 (1988-07-01), pages 53 - 57, XP000652325, ISSN: 0036-8075 * |
RIECHMANN L AND WEILL M: "Phage display and selection of a site-directed randomized single-chain antibody Fv fragment for its affinity improvement", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 32, no. 34, 31 August 1993 (1993-08-31), pages 8848 - 8855, XP002147197, ISSN: 0006-2960 * |
SCHULTZ S ET AL: "Site-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71", March 1986, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, PAGE(S) 1588-1592, ISSN: 0027-8424, XP002147196 * |
SHANKLIN J ED - ZHANG QIFA WING ROD: "Exploring the possibilities presented by protein engineering", CURRENT OPINION IN PLANT BIOLOGY, QUADRANT SUBSCRIPTION SERVICES, GB, vol. 3, no. 3, 1 January 2000 (2000-01-01), pages 243 - 248, XP004793029, ISSN: 1369-5266 * |
SHANKLIN J: "Exploring the possibilities presented by protein engineering", CURRENT OPINION IN PLANT BIOLOGY, QUADRANT SUBSCRIPTION SERVICES, GB, vol. 3, no. 3, 2000, pages 243 - 248, XP004793029, ISSN: 1369-5266 * |
Also Published As
Publication number | Publication date |
---|---|
EP1073710A2 (en) | 2001-02-07 |
IL138206A (en) | 2011-06-30 |
IL138206A0 (en) | 2001-10-31 |
MXPA00009723A (en) | 2003-09-22 |
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Legal Events
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