EP1036146B1 - DISHWASHING DETERGENT WITH ANTIBACTERIAL and antiviral ACTION - Google Patents

DISHWASHING DETERGENT WITH ANTIBACTERIAL and antiviral ACTION Download PDF

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Publication number
EP1036146B1
EP1036146B1 EP98958927A EP98958927A EP1036146B1 EP 1036146 B1 EP1036146 B1 EP 1036146B1 EP 98958927 A EP98958927 A EP 98958927A EP 98958927 A EP98958927 A EP 98958927A EP 1036146 B1 EP1036146 B1 EP 1036146B1
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EP
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Prior art keywords
weight
use according
composition comprises
surfactants
salts
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EP98958927A
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German (de)
French (fr)
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EP1036146A1 (en
Inventor
Brigitte Giesen
Dagmar Zaika
Hans Andree
Michael Heinzel
Norbert Stelter
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Henkel AG and Co KGaA
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Henkel AG and Co KGaA
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2075—Carboxylic acids-salts thereof
    • C11D3/2086—Hydroxy carboxylic acids-salts thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02—Anionic compounds
    • C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
    • C11D1/146—Sulfuric acid esters
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02—Anionic compounds
    • C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/29—Sulfates of polyoxyalkylene ethers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/662—Carbohydrates or derivatives
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/90—Betaines

Definitions

  • the invention relates to dishwashing detergent which, when used in a concentrated manner, has an antibacterial effect Show effect, i. undiluted use inhibition of bacterial Cause growth and beyond a number of bacteria in significant Kill the circumference; At the same time, these funds are also against the kitchen hygiene relevant herpes viruses are effective.
  • a modern hand dishwashing detergent must also have a special property spectrum excellent cleaning, skin compatibility, temperature and storage stability and ecological compatibility.
  • Antibacterial rinsing agents are known in the art.
  • a bacteriostatic Component are u.a. Triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether), natural or nature-identical extracts, such as e.g. Extracts from the orange peel, pine oil, geraniol, Nerol etc. used.
  • a use of ecologically and economically acceptable triclosan amounts leads to it a sufficient antibacterial effect at 100% application concentration, when testing the antibacterial properties at a use concentration of 50% but no sufficient inhibitory effect on bacterial growth is given more.
  • the bacteriostatic effect is not enough, too a sufficient inhibition of bacterial growth when using the hand dishwashing detergent using damp dish cloths, sponges or brushes.
  • Chloramine-T toluenesulphonylchloramide-sodium salt
  • Germall® 115 imidazolidinyl urea
  • sodium formate 2-phenoxyethanol, 1-phenoxy-2-propanol, 2-Phenoxy-1-propanol
  • Chloramine-T toluenesulphonylchloramide-sodium salt
  • Germall® 115 imidazolidinyl urea
  • sodium formate 2-phenoxyethanol
  • 1-phenoxy-2-propanol 2-Phenoxy-1-propanol
  • 2-Phenoxy-1-propanol showed in particular at 50% use concentration no adequate antibacterial effect.
  • WO-A-95/35364 describes a Synergy between amphoteric surfactants, nonionic alkoxylated alcohols and some aromatic carboxylic acids, e.g. Salicylate.
  • WO-A-96/17918 describes a synergy between nonionic surfactant and carboxylic acid for a disinfecting detergent product comprising the combination of nonionic ethoxylated alcohol surfactant, anionic surfactant, amphoteric surfactant and an antimicrobial such as benzoic acid derivatives, dicarboxylic acids, C 1 -C 6 alcohols.
  • compositions proposed in the prior art are suitable as any perfumable, excellent cleansing, hypoallergenic, temperaturund storage-stable and ecologically particularly compatible hand dishwashing detergent with specific antibacterial Efficacy with concentrated application on wet work surfaces, Kitchen utensils using damp dishcloths. Sponges and brushes.
  • the subject of the present invention is therefore the use of an agent containing Surfactant mixtures of anionic surfactants and / or nonionic surfactants and / or betaine surfactants, and one or more carboxylic acids and / or their salts with antibacterial effect, as antibacterial and antiviral effective against herpes viruses Hand dishwashing detergents.
  • Carboxylic acids or carboxylic acid salts in the context of the present invention are especially benzoic acid (phenylformic acid), lactic acid (2-hydroxypropionic acid), Salicylic acid (2-hydroxybenzoic acid), sorbic acid (2,4-hexadienoic acid) or their Mixtures and / or their sodium, potassium, magnesium or calcium salts and their mixtures.
  • a use concentration between 0.1 and 8 wt .-%, preferably between 0.5 and 6 wt .-% and particularly preferably between 1 and 4% by weight.
  • Germall® 115 allows - while maintaining the good bacteriostatic properties -
  • the amount of carboxylic acid and / or carboxylic acid salt drastically reduce.
  • the suitable amount of carboxylic acid and / or carboxylic acid salt is in the Case of combined use of active ingredient between 0.05 and 2 wt .-%, preferably between 0.1 and 1 wt .-% and particularly preferably between 0.2 and 0.5 wt .-%.
  • the Use amount of imidazolidinyl urea in this case is between 0.05 and 2 wt .-%, preferably between 0.1 and 1.5% by weight and more preferably between 0.2 and 1% by weight.
  • Suitable surfactant mixtures are especially those of anionic and nonionic Surfactants. But the additional use of Betaintensiden in the mixture can be very useful for many applications. Overall, the surfactants are used in Amounts of from 0.4 to 50% by weight, preferably from 1 to 45% by weight, more preferably from 3 to 42% by weight and most preferably 5 to 40% by weight.
  • Anionic surfactants according to the present invention may include aliphatic sulfates such as Fatty alcohol sulfates, fatty alcohol ether sulfates, dialkyl ether sulfates, monoglyceride sulfates and aliphatic sulfonates such as alkanesulfonates, olefinsulfonates, ether sulfonates, n-alkyl ether sulfonates, Estersulfonate, and Lingninsulfonate be.
  • aliphatic sulfates such as Fatty alcohol sulfates, fatty alcohol ether sulfates, dialkyl ether sulfates, monoglyceride sulfates and aliphatic sulfonates such as alkanesulfonates, olefinsulfonates, ether sulfonates, n-alkyl ether sulfonates, Estersulfonate, and
  • fatty alcohol ether sulfates are products of sulfation reactions on alkoxylated Alcohols.
  • alkoxylated alcohols Reaction products of alkylene oxide, preferably ethylene oxide, with alcohols, preferred in the context of the present invention, the longer-chain alcohols.
  • alkylene oxide preferably ethylene oxide
  • alcohols preferred in the context of the present invention, the longer-chain alcohols.
  • Another embodiment is the use of mixtures of alkylene oxides preferably the mixture of ethylene oxide and propylene oxide.
  • lower ethoxylated fatty alcohols 0.5-4 mol EO, preferably 1 - 2 mol EO).
  • the anionic surfactants are preferably used in amounts of between 0.2 and 39.8% by weight. used, preferably 5 to 35 wt .-%, particularly preferably 10 to 32 wt .-%. But also amounts to about 45 wt .-% can be used, for. When the use of fatty alcohol sulfates is intended.
  • Nonionic surfactants in the context of the present invention may be alkoxylates such as polyglycol ethers, fatty alcohol polyglycol ethers, alkylphenol polyglycol ethers, end-group-linked Polyglycol ethers, mixed ethers and hydroxy mixed ethers and fatty acid polyglycol esters be. Also useful are ethylene oxide, propylene oxide, block polymers and fatty acid alkanolamides and fatty acid polyglycol ethers.
  • An important class Nonionic surfactants which can be used according to the invention are the polyol surfactants and especially the glucosurfactants, such as alkylpolyglycosides and fatty acid glucamides. Particularly preferred are the alkyl polyglucosides.
  • Alkylpolyglycosides are surfactants which can be obtained by the reaction of sugars and alcohols according to the relevant processes of preparative organic chemistry, wherein, depending on the nature of the preparation, a mixture of monoalkylated, oligomeric or polymeric sugars is obtained.
  • Preferred alkylpolyglycosides can be alkylpolyglucosides, the alcohol being particularly preferably a long-chain fatty alcohol or a mixture of long-chain fatty alcohols having branched or unbranched alkyl chain lengths between C 8 and C 18 and the degree of oligomerization of the sugars between 1 and 10.
  • alkylpolyglycosides in amounts of between 0.1 to 14.9 wt .-%, preferably 0.5 to 8 wt .-% and particularly preferably 1 to 6 wt .-%.
  • alkylbetaines the alkylamidobetaines, the imidazolinium betaines can be included and the aminopropionates, as well as the sulfobetaines and biosurfactants.
  • One. preferred Ingredient is alkylamidobetaine.
  • amphoteric surfactants are preferably used in amounts of from 0.1 to 14.9% by weight, preferably 0.5 to 8 wt .-% and particularly preferably 1 to 6 wt .-%, used.
  • the hand dishwashing detergent contains as surfactant mixture (a) 0.2 to 39.8 wt .-%, preferably 5 to 35 wt .-%, particularly preferably 10 to 32 wt .-%, anionic surfactants, preferably fatty alcohol ether sulfates and / or fatty alcohol sulfates, (b) 0.1 to 14.9% by weight, preferably 0.5 to 8% by weight, and especially preferably 1 to 6% by weight, nonionic surfactants, preferably alkyl polyglucosides, and (c) 0.1 to 14.9 wt%, preferably 0.5 to 8 wt%, and more preferably 1 to 6 wt .-%, betaine surfactants, preferably Alkylamidobetaine.
  • anionic surfactants preferably fatty alcohol ether sulfates and / or fatty alcohol sulfates
  • anionic surfactants preferably fatty alcohol ether sulfates and / or fatty alcohol sulf
  • solubilizer such as dyes and perfume oils, for example, alkanolamines, Polyols such as ethylene glycol, propylene glycol, 1,2 glycerol and other mono- and polyvalent ones Alcohols, as well as alkylbenzenesulfonates having 1 to 3 carbon atoms in the alkyl radical serve.
  • solvents for example, one or more low molecular weight alcohols, e.g. Ethanol. They contribute to Incorporation of perfume and dye at, prevent the formation of liquid crystalline Phases and contribute to the formation of clear products. According to the invention between 0 and 12% by weight, preferably between 3 and 10% by weight, more preferably between 5 and 8% by weight of solvent.
  • customary ingredients such as defoamers (for example, silicone oils, paraffin oils or mineral oils), Structurants, perfumes, dyes, corrosion inhibitors and preservatives be contained in amounts up to 5 wt .-%.
  • the antibacterial effect of the hand dishwashing detergent according to the invention is illustrated by way of example in the following formulations (in the tables of Examples 1 and 2, the unit% stands for% by weight).
  • the indicated pH values were adjusted with citric acid.
  • basic formulation 31.5 Wt% C 12-14 fatty alcohol ether sulfate (1.3 EO) 3.0 Wt% C 8-16 alkyl polyglucoside d p 1.4 5.0 Wt% cocoamidopropyl betaine 3.5 %
  • dicarboxylic acid mixture Sokalan®-DSC-Na
  • x Wt .-% ethanol y Wt .-% active ingredient ad 100.0 Wt .-% water recipe 1 2 3 4 5 6 7 active substance 2.0% benzoic acid 3.0% lactic acid 0.3% Germall® 115 + 0.2% salicylic acid 0.1% triclosan (Irgasan® DP300) 0.2% chloramine T (halamid) 3.0% benzyl alcohol 0.5% imidazolinidyl
  • the antiviral effect of hand dishwashing detergent according to the invention is further exemplified in the formulations completely effective against herpes viruses 8 and 9 on the basis of the following basic formulation.
  • both formulations contained small amounts of color and perfume.
  • Citric acid was used to adjust the pH to 5.2.
  • the exposure time was 15 minutes at the test concentrations indicated in the table.

Abstract

The invention relates to an especially compatible hand dishwashing detergent which can be perfumed in any way, cleans excellently, is skin compatible, temperature-stable, stable in storage, and ecological. The detergent has a specific antibacterial activity during concentrated application on wet work surfaces, kitchen appliances while using wet cleaning towels, sponges and brushes. The detergent is provided by adding one or more carboxylic acids and/or the salts thereof having antibacterial action to a tensidic mixture comprised of anionic tensides and/or nonanionic tensides and/or betaine tensides.

Description

Die Erfindung betrifft Geschirrspülmittel, die bei konzentrierter Anwendung eine antibakterielle Wirkung zeigen, d.h. bei unverdünnter Anwendung eine Hemmung des bakteriellen Wachstums bewirken und darüber hinaus eine Reihe von Bakterien in erheblichem Umfange abtöten; gleichzeitig sind diese Mittel auch gegen die küchenhygienisch relevanten Herpes-Viren wirksam.The invention relates to dishwashing detergent which, when used in a concentrated manner, has an antibacterial effect Show effect, i. undiluted use inhibition of bacterial Cause growth and beyond a number of bacteria in significant Kill the circumference; At the same time, these funds are also against the kitchen hygiene relevant herpes viruses are effective.

Eine der meist unterschätzten Gesundheitsgefahren sind die hygienischen Verhältnisse in der Küche. Krankheitserregende Bakterien können sich - insbesondere nach Verarbeitung von Eiern, rohem Fleisch und rohem Fisch - auf Arbeitsflächen und Küchengeräten, wie z.B. Schneidbrettern vermehren und damit eine ernste Gefahr darstellen.One of the most underestimated health hazards are the hygienic conditions in the kitchen. Pathogenic bacteria can - especially after processing of eggs, raw meat and raw fish - on work surfaces and kitchen appliances, such as e.g. Increase cutting boards and pose a serious danger.

Versucht man mit herkömmlichen Geschirrspülmitteln eine bakteriostatische Wirkung zu erreichen, so stellt man bei der Überprüfung der antibakteriellen Wirksamkeit schnell fest, daß eine Reihe von Handgeschirrspülmittel schon bei konzentrierter Anwendung keine ausreichende Wachstumshemmung oder gar Keimabtötung bewirken.Tried with conventional dishwashing agents to a bacteriostatic effect achieve rapid results when testing antibacterial efficacy, that a number of hand dishwashing detergents even with concentrated use no cause sufficient growth inhibition or even killing germs.

Die Anwendung von konzentriertem Produkt auf feuchten Arbeitsflächen oder Küchengeräten unter Zuhilfenahme von feuchten Spülschwämmen, Tüchern oder Bürsten führt zudem zwangsläufig zu einer Verdünnung des Handgeschirrspülmittels und damit zu einer weiter reduzierten antibakteriellen Wirkung.The application of concentrated product on wet work surfaces or kitchen appliances with the help of moist rinse sponges, towels or brushes leads also inevitably to a dilution of the hand dishwashing detergent and thus to a further reduced antibacterial effect.

Eine Überprüfung der antibakteriellen Wirkung von Handgeschirrspülmittelformulierungen nach dem in der Desinfektionsmittelprüfung anerkannten "quantitativen Suspensionstest" der DGHM (Deutsche Gesellschaft für Hygiene und Mikrobiologie), bei dem die Zahl überlebender Keime nach Ablauf einer definierten, praxisrelevanten Einwirkzeit in Abhängigkeit von der Einsatzkonzentration bestimmt wird, hat nun gezeigt, daß schon bei Einsatz einer 50 %igen Spülmittelverdünnung eine Reihe von Konservierungsmittelhaltigen Rezepturen keine ausreichende bakteriostatische Wirkung aufweisen. Aufgabe der Erfindung war es nun, ein Handgeschirrspülmittel zu formulieren, das auch bei 50 %iger Verdünnung noch eine deutliche Hemmung des Bakterienwachstums und zudem in hohem Maße eine Keimabtötung bewirkt.A review of the antibacterial effect of hand dishwashing detergent formulations after the "quantitative suspension test" recognized in the disinfectant test the DGHM (German society for hygiene and microbiology), with which the number Surviving germs after expiration of a defined, practice-relevant exposure time in dependence has been determined by the use concentration has now shown that already at Use of a 50% detergent dilution a range of preservative-containing Formulations have no sufficient bacteriostatic effect. The object of the invention was now to formulate a hand dishwashing detergent, which also at 50% dilution still a significant inhibition of bacterial growth and also causes a high degree of germ killing.

Daneben muß ein modernes Handgeschirrspülmittel auch ein besonderes Eigenschaftsspektrum aufweisen, welches ausgezeichnete Reinigung, Hautverträglichkeit, Temperatur- und Lagerstabilität und ökologische Verträglichkeit umfaßt.In addition, a modern hand dishwashing detergent must also have a special property spectrum excellent cleaning, skin compatibility, temperature and storage stability and ecological compatibility.

Antibakterielle Spülmittel sind im Stand der Technik bekannt. Als bakteriostatische Komponente werden u.a. Triclosan (2,4,4'-Trichlor-2'-hydroxydiphenylether), natürliche bzw. natur-identische Extrakte, wie z.B. Extrakte aus der Orangenschale, Pineöl, Geraniol, Nerol usw. verwendet.Antibacterial rinsing agents are known in the art. As a bacteriostatic Component are u.a. Triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether), natural or nature-identical extracts, such as e.g. Extracts from the orange peel, pine oil, geraniol, Nerol etc. used.

Ein Einsatz ökologisch und ökonomisch vertretbarer Triclosan-Mengen führt zwar zu einer ausreichenden antibakteriellen Wirkung bei 100 %iger Anwendungskonzentration, bei Prüfung der antibakteriellen Eigenschaften bei einer Einsatzkonzentration von 50 % ist aber keine ausreichende Hemmwirkung auf das Bakterienwachstum mehr gegeben.A use of ecologically and economically acceptable triclosan amounts leads to it a sufficient antibacterial effect at 100% application concentration, when testing the antibacterial properties at a use concentration of 50% but no sufficient inhibitory effect on bacterial growth is given more.

Arbeitet man relativ hohen Mengen natürlicher oder naturidentischer Extrakte ein, so ergeben sich - neben Problemen bei der homogenen Einarbeitung der Wirkstoffe - auch Parfümierungprobleme, da die geruchsintensiven Extrakte nicht oder nur mühsam in die vom Entwickler gewünschte Duftrichtung überparfümiert werden können.If one works relatively high amounts of natural or nature-identical extracts, then yield - besides problems with the homogeneous incorporation of the active ingredients - also Perfuming problems, since the odorous extracts are difficult or impossible in the can be over-perfumed by the developer desired fragrance direction.

Bei niedrigen Einsatzmengen reicht die bakteriostatische Wirkung nicht aus, um auch eine ausreichende Hemmung des Bakterienwachstums bei Anwendung des Handgeschirrspülmittels unter Nutzung feuchter Spültücher, Schwämme oder Bürsten zu garantieren.At low levels, the bacteriostatic effect is not enough, too a sufficient inhibition of bacterial growth when using the hand dishwashing detergent using damp dish cloths, sponges or brushes.

Andere Wirkstoffe, wie z.B. Chloramin-T (Toluolsulfonsäurechloramid-Natriumsalz), Germall® 115 (Imidazolidinyl-Harnstoff), Natriumformiat, 2-Phenoxyethanol, 1-Phenoxy-2-propanol, 2-Phenoxy-1-propanol zeigten insbesondere bei 50 %iger Einsatzkonzentration keine ausreichende antibakterielle Wirkung.Other agents, e.g. Chloramine-T (toluenesulphonylchloramide-sodium salt), Germall® 115 (imidazolidinyl urea), sodium formate, 2-phenoxyethanol, 1-phenoxy-2-propanol, 2-Phenoxy-1-propanol showed in particular at 50% use concentration no adequate antibacterial effect.

Für ein antimirobielles Reinigungsmittelprodukt für Oberflächen beschreibt WO-A-95/35364 eine Synergie zwischen amphoteren Tensiden, nichtionischen alkoxylierten Alkoholen sowie einigen aromatischen Carbonsäuren, wie z.B. Salicylat.For an antiperspirant cleaning product for Surfaces WO-A-95/35364 describes a Synergy between amphoteric surfactants, nonionic alkoxylated alcohols and some aromatic carboxylic acids, e.g. Salicylate.

WO-A-96/17918 beschreibt eine Synergie zwischen nichtionischem Tensid und Carbonsäure für ein desinfizierendes Reinigungsmittelprodukt, mit der Kombination aus nichtionischem ethoxyliertem Alkoholtensid, anionischem Tensid, amphoterem Tensid und einem antimikrobiellem Mittel wie z.B. Benzoesäurederivate, Dicarbonsäuren, C1-C6 Alkohole.WO-A-96/17918 describes a synergy between nonionic surfactant and carboxylic acid for a disinfecting detergent product comprising the combination of nonionic ethoxylated alcohol surfactant, anionic surfactant, amphoteric surfactant and an antimicrobial such as benzoic acid derivatives, dicarboxylic acids, C 1 -C 6 alcohols.

Keine im Stand der Technik vorgeschlagenen Zusammensetzungen eignet sich demnach als beliebig parfümierbares, ausgezeichnet reinigendes, hautverträgliches, temperaturund lagerstabiles und ökologisch besonders verträgliches Handgeschirrspülmittel mit spezifischer-antibakterieller Wirksamkeit bei konzentrierter Anwendung auf feuchten Arbeitsflächen, Küchengeräten unter Nutzung feuchter Spültücher. Schwämme und Bürsten.Accordingly, no compositions proposed in the prior art are suitable as any perfumable, excellent cleansing, hypoallergenic, temperaturund storage-stable and ecologically particularly compatible hand dishwashing detergent with specific antibacterial Efficacy with concentrated application on wet work surfaces, Kitchen utensils using damp dishcloths. Sponges and brushes.

Problemlos parfümierbare, ausgezeichnet reinigende, hautverträgliche, temperatur- und lagerstabile und ökologisch besonders verträgliche Produkte mit guter antibakterieller Wirksamkeit bei konzentrierter Anwendung erhält man, wenn man ein Gemisch aus Fettalkoholethersulfat, ggf. Fettalkoholsulfat, Alkylpolyglykosid und Betain zusammen mit einer Carbonsäure bzw. deren Salze bereitstellt.Easily perfumable, excellent cleansing, hypoallergenic, temperature and storage-stable and environmentally friendly products with good antibacterial properties Efficacy in concentrated use is obtained when a mixture of Fatty alcohol ether sulfate, optionally fatty alcohol sulfate, alkyl polyglycoside and betaine together with a carboxylic acid or salts thereof provides.

Diese Mittel weisen überraschenderweise eine gute antivirale Wirksamkeit gegen die küchenhygienisch relevanten Herpes-Viren auf, mit denen Besteckteile und Gläser bei der Benutzung durch infektiöse Personen leicht kontaminiert werden können.These agents surprisingly have a good antiviral activity against the kitchen hygiene relevant herpes viruses, with which cutlery and glasses in the Use by infectious persons can be easily contaminated.

Gegenstand vorliegender Erfindung ist demnach die Verwendung eines Mittels, enthaltend Tensidmischungen aus anionischen Tensiden und/oder nichtionischen Tensiden und/oder Betaintensiden, sowie eine oder mehrere Carbonsäuren und/oder deren Salze mit antibakterieller Wirkung, als antibakteriell und gegen Herpes-Viren antiviral wirksames Handgeschirrspülmittel.The subject of the present invention is therefore the use of an agent containing Surfactant mixtures of anionic surfactants and / or nonionic surfactants and / or betaine surfactants, and one or more carboxylic acids and / or their salts with antibacterial effect, as antibacterial and antiviral effective against herpes viruses Hand dishwashing detergents.

Carbonsäuren bzw. Carbonsäuresalze im Sinne der vorliegenden Erfindung sind besonders Benzoesäure (Phenylameisensäure), Milchsäure (2-Hydroxypropionsäure), Salicylsäure (2-Hydroxybenzoesäure), Sorbinsäure (2,4-Hexadiensäure) oder deren Mischungen und/oder deren Natrium-, Kalium-, Magnesium- oder Calciumsalze sowie deren Mischungen.Carboxylic acids or carboxylic acid salts in the context of the present invention are especially benzoic acid (phenylformic acid), lactic acid (2-hydroxypropionic acid), Salicylic acid (2-hydroxybenzoic acid), sorbic acid (2,4-hexadienoic acid) or their Mixtures and / or their sodium, potassium, magnesium or calcium salts and their mixtures.

Es wurde überraschend gefunden, daß besonders geeignete antibakterielle Wirkstoffe Benzoesäure und/oder deren Natriumsalz, Salicylsäure und/oder deren Natriumsalz, Milchsäure und/oder deren Natriumsalz sowie Mischungen von zwei oder mehreren Carbonsäuren und/oder deren Salze sind. Insbesondere geeignet ist die Benzoesäure.It has surprisingly been found that particularly suitable antibacterial agents Benzoic acid and / or its sodium salt, salicylic acid and / or its sodium salt, Lactic acid and / or its sodium salt and mixtures of two or more Carboxylic acids and / or salts thereof are. Particularly suitable is benzoic acid.

Zur Sicherstellung einer ausreichenden Hemmung des Bakterienwachstums sowie zu einer möglichst hohen Keimabtötungsrate ist eine Einsatzkonzentration zwischen 0,1 und 8 Gew.-%, bevorzugt zwischen 0,5 und 6 Gew.-% und besonders bevorzugt zwischen 1 und 4 Gew.-%, anzustreben.To ensure sufficient inhibition of bacterial growth as well as to the highest possible germ killing rate is a use concentration between 0.1 and 8 wt .-%, preferably between 0.5 and 6 wt .-% and particularly preferably between 1 and 4% by weight.

Überraschenderweise wurde zudem gefunden, daß es eine kombinierte Verwendung von Carbonsäuren und/oder Carbonsäuresalzen zusammen mit Imidazolinidyl-Harnstoff, z.B. Surprisingly, it has also been found that there is a combined use of Carboxylic acids and / or carboxylic acid salts together with imidazolinidyl urea, e.g.

Germall® 115, ermöglicht, - unter Beibehaltung der guten bakteriostatischen Eigenschaften - die Einsatzmenge an Carbonsäure und/oder Carbonsäuresalz drastisch zu senken. Die geeignete Einsatzmenge an Carbonsäure und/oder Carbonsäuresalz liegt im Falle eines kombinierten Wirkstoffeinsatzes zwischen 0,05 und 2 Gew.-%, bevorzugt zwischen 0,1 und 1 Gew.-% und besonders bevorzugt zwischen 0,2 und 0,5 Gew.-%. Die Einsatzmenge an Imidazolidinyl-Harnstoff liegt in diesem Fall zwischen 0,05 und 2 Gew.-%, bevorzugt zwischen 0,1 und 1,5 Gew.-% und besonders bevorzugt zwischen 0,2 und 1 Gew.-%.Germall® 115, allows - while maintaining the good bacteriostatic properties - The amount of carboxylic acid and / or carboxylic acid salt drastically reduce. The suitable amount of carboxylic acid and / or carboxylic acid salt is in the Case of combined use of active ingredient between 0.05 and 2 wt .-%, preferably between 0.1 and 1 wt .-% and particularly preferably between 0.2 and 0.5 wt .-%. The Use amount of imidazolidinyl urea in this case is between 0.05 and 2 wt .-%, preferably between 0.1 and 1.5% by weight and more preferably between 0.2 and 1% by weight.

Es wurde außerdem gefunden, daß - im Sinne der Erfindung - eine Carbonsäureund/oder Carbonsäuresalz-haltige Spülmittelformulierung bei einem pH-Wert im Fertigprodukt zwischen 4 und 6, bevorzugt zwischen 4,5 und 5,5, besonders bevorzugt zwischen 4,9 und 5,3, die stärkste antibakterielle Wirksamkeit gepaart mit der günstigsten Lagerstabilität aufweist.It has also been found that - in the context of the invention - a carboxylic acid and / or Carboxylic acid salt-containing detergent formulation at a pH in the finished product between 4 and 6, preferably between 4.5 and 5.5, more preferably between 4.9 and 5.3, the strongest antibacterial activity paired with the cheapest Shelf life has.

Als Tensidmischungen eignen sich besonders jene aus anionischen und nichtionischen Tensiden. Aber auch die zusätzliche Verwendung von Betaintensiden im Gemisch kann für viele Anwendungen sehr sinnvoll sein. Insgesamt verwendet man die Tenside in Mengen von 0,4 bis 50 Gew.-, bevorzugt von 1 bis 45 Gew.-%, besonders bevorzugt 3 bis 42 Gew.- und äußerst bevorzugt 5 bis 40 Gew.-%.Suitable surfactant mixtures are especially those of anionic and nonionic Surfactants. But the additional use of Betaintensiden in the mixture can be very useful for many applications. Overall, the surfactants are used in Amounts of from 0.4 to 50% by weight, preferably from 1 to 45% by weight, more preferably from 3 to 42% by weight and most preferably 5 to 40% by weight.

Anionische Tenside gemäß der vorliegenden Erfindung können aliphatische Sulfate wie Fettalkoholsulfate, Fettalkoholethersulfate, Dialkylethersulfate, Monoglyceridsulfate und aliphatische Sulfonate wie Alkansulfonate, Olefinsulfonate, Ethersulfonate, n-Alkylethersulfonate, Estersulfonate, und Lingninsulfonate sein. Ebenfalls im Rahmen der vorliegenden Erfindung verwendbar sind Fettsäurecyanamide, Sulfobernsteinsäureester, Fettsäureisethionate, Acylaminoalkansulfonate (Fettsäuretauride), Fettsäuresarcosinate, Ethercarbonsäuren und Alkyl(ether)phosphate. Anionic surfactants according to the present invention may include aliphatic sulfates such as Fatty alcohol sulfates, fatty alcohol ether sulfates, dialkyl ether sulfates, monoglyceride sulfates and aliphatic sulfonates such as alkanesulfonates, olefinsulfonates, ether sulfonates, n-alkyl ether sulfonates, Estersulfonate, and Lingninsulfonate be. Also in the context of the present Fatty acid cyanamides, sulfosuccinic acid esters, fatty acid isethionates, Acylaminoalkanesulfonates (fatty acid taurides), fatty acid sarcosinates, ether carboxylic acids and alkyl (ether) phosphates.

Besonders bevorzugt im Rahmen der vorliegenden Erfindung sind die Fettalkoholethersulfate. Fettalkoholethersulfate sind Produkte von Sulfatierreaktionen an alkoxylierten Alkoholen. Dabei versteht der Fachmann allgemein unter alkoxylierten Alkoholen die Reaktionsprodukte von Alkylenoxid, bevorzugt Ethylenoxid, mit Alkoholen, bevorzugt im Sinne der vorliegenden Erfindung die längerkettigen Alkohole. In der Regel enstehen aus n Molen Ethylenoxid und einem Mol Alkohol, abhängig von den Reaktionsbedingungen ein komplexes Gemisch von Additionsprodukten unterschiedlichen Ethoxylierungsgrades. Eine weitere Ausführungsform besteht im Einsatz von Gemischen der Alkylenoxide bevozugt des Gemisches von Ethylenoxid und Propylenoxid. Ganz besonders bevorzugt im Sinne der vorliegenden Erfindung sind niederethoxylierte Fettalkohole (0,5 - 4 mol EO, bevorzugt 1 - 2 mol EO).Particularly preferred in the context of the present invention are the fatty alcohol ether sulfates. Fatty alcohol ether sulfates are products of sulfation reactions on alkoxylated Alcohols. The skilled worker will generally understand the alkoxylated alcohols Reaction products of alkylene oxide, preferably ethylene oxide, with alcohols, preferred in the context of the present invention, the longer-chain alcohols. Usually arise from n moles of ethylene oxide and one mole of alcohol, depending on the reaction conditions a complex mixture of addition products of different degrees of ethoxylation. Another embodiment is the use of mixtures of alkylene oxides preferably the mixture of ethylene oxide and propylene oxide. Very particularly preferred For the purposes of the present invention, lower ethoxylated fatty alcohols (0.5-4 mol EO, preferably 1 - 2 mol EO).

Bevorzugt werden die anionischen Tenside in Mengen zwischen 0,2 und 39,8 Gew.-% eingesetzt, bevorzugt 5 bis 35 Gew.-%, besonders bevorzugt 10 bis 32 Gew.-%. Aber auch Mengen bis ungefähr 45 Gew.-% können verwendet werden, z. B. wenn die Verwendung von Fettalkoholsulfaten beabsichtigt wird.The anionic surfactants are preferably used in amounts of between 0.2 and 39.8% by weight. used, preferably 5 to 35 wt .-%, particularly preferably 10 to 32 wt .-%. But also amounts to about 45 wt .-% can be used, for. When the use of fatty alcohol sulfates is intended.

Nichtionische Tenside im Rahmen der vorliegenden Erfindung können Alkoxylate sein wie Polyglycolether, Fettalkoholpolygycolether, Alkylphenolpolyglycolether, endgruppenver-schlossene Polyglycolether, Mischether und Hydroxymischether und Fettsäurepolyglycolester sein. Ebenfalls verwendbar sind Ethylenoxid, Propylenoxid, Blockpolymere und Fettsäurealkanolamide und Fettsäurepolyglycolether. Eine wichtige Klasse nichtionischer Tenside die erfindungsgemäß verwendet werden kann, sind die Polyol-Tenside und hier besonders die Glucotenside, wie Alkylpolyglycoside und Fettsäureglucamide. Besonders bevorzugt sind die Alkylpolyglucoside.Nonionic surfactants in the context of the present invention may be alkoxylates such as polyglycol ethers, fatty alcohol polyglycol ethers, alkylphenol polyglycol ethers, end-group-linked Polyglycol ethers, mixed ethers and hydroxy mixed ethers and fatty acid polyglycol esters be. Also useful are ethylene oxide, propylene oxide, block polymers and fatty acid alkanolamides and fatty acid polyglycol ethers. An important class Nonionic surfactants which can be used according to the invention are the polyol surfactants and especially the glucosurfactants, such as alkylpolyglycosides and fatty acid glucamides. Particularly preferred are the alkyl polyglucosides.

Alkylpolyglycoside sind Tenside, die durch die Reaktion von Zuckern und Alkoholen nach den einschlägigen Verfahren der präparativen organischen Chemie erhalten werden können, wobei es je nach Art der Herstellung zu einem Gemisch monoalkylierter, oligomerer oder polymerer Zucker kommt. Bevorzugte Alkylpolyglykoside können Alkylpolyglucoside sein, wobei besonders bevorzugt der Alkohol ein langkettiger Fettalkohol ist oder ein Gemisch langkettiger Fett-alkohole ist mit verzweigten oder unverzweigten Alkylkettenlängen zwischen C8 und C18 und der Oligomerisierungsgrad der Zucker zwischen 1 und 10 ist. Alkylpolyglycosides are surfactants which can be obtained by the reaction of sugars and alcohols according to the relevant processes of preparative organic chemistry, wherein, depending on the nature of the preparation, a mixture of monoalkylated, oligomeric or polymeric sugars is obtained. Preferred alkylpolyglycosides can be alkylpolyglucosides, the alcohol being particularly preferably a long-chain fatty alcohol or a mixture of long-chain fatty alcohols having branched or unbranched alkyl chain lengths between C 8 and C 18 and the degree of oligomerization of the sugars between 1 and 10.

Besonders bevorzugt verwendet man die Alkylpolyglycoside in Mengen zwischen 0,1 bis 14,9 Gew.-%, bevorzugt 0,5 bis 8 Gew.-% und besonders bevorzugt 1 bis 6 Gew.-%.Particular preference is given to using the alkylpolyglycosides in amounts of between 0.1 to 14.9 wt .-%, preferably 0.5 to 8 wt .-% and particularly preferably 1 to 6 wt .-%.

Zu den zwitterionischen Tensiden oder Amphotensiden, die erfindungsgemäß eingesetzt werden können, zählen die Alkylbetaine, die Alkylamidobetaine, die Imidazoliniumbetaine und die Aminopropionate, genauso wie die Sulfobetaine und Biotenside. Ein. bevorzugter Inhaltsstoff ist Alkylamidobetain.To the zwitterionic surfactants or amphoteric surfactants used according to the invention The alkylbetaines, the alkylamidobetaines, the imidazolinium betaines can be included and the aminopropionates, as well as the sulfobetaines and biosurfactants. One. preferred Ingredient is alkylamidobetaine.

Bevorzugt werden diese Amphotenside in Mengen zwischen, 0,1 bis 14,9 Gew.-%, bevorzugt 0,5 bis 8 Gew.-% und besonders bevorzugt 1 bis 6 Gew.-%, eingesetzt.These amphoteric surfactants are preferably used in amounts of from 0.1 to 14.9% by weight, preferably 0.5 to 8 wt .-% and particularly preferably 1 to 6 wt .-%, used.

In einer bevorzugten Ausführungsform der Erfindung enthält das Handgeschirrspülmittel als Tensidmischung (a) 0,2 bis 39,8 Gew.-%, bevorzugt 5 bis 35 Gew.-%, besonders bevorzugt 10 bis 32 Gew.-%, anionische Tenside, vorzugsweise Fettalkoholethersulfate und/oder Fettalkoholsulfate, (b) 0,1 bis 14,9 Gew.-%, bevorzugt 0,5 bis 8 Gew.-% und besonders bevorzugt 1 bis 6 Gew.-%, nichtionische Tenside, vorzugsweise Alkylpolyglucoside, und (c) 0,1 bis 14,9 Gew.-%, bevorzugt 0,5 bis 8 Gew.-% und besonders bevorzugt 1 bis 6 Gew.-%, Betaintenside, vorzugsweise Alkylamidobetaine.In a preferred embodiment of the invention, the hand dishwashing detergent contains as surfactant mixture (a) 0.2 to 39.8 wt .-%, preferably 5 to 35 wt .-%, particularly preferably 10 to 32 wt .-%, anionic surfactants, preferably fatty alcohol ether sulfates and / or fatty alcohol sulfates, (b) 0.1 to 14.9% by weight, preferably 0.5 to 8% by weight, and especially preferably 1 to 6% by weight, nonionic surfactants, preferably alkyl polyglucosides, and (c) 0.1 to 14.9 wt%, preferably 0.5 to 8 wt%, and more preferably 1 to 6 wt .-%, betaine surfactants, preferably Alkylamidobetaine.

Als Lösungsvermittler, etwa für Farbstoffe und Parfümöle können beispielsweise Alkanolamine, Polyole wie Ethylenglycol, Propylenglycol, 1,2 Glycerin und andere ein- und mehrwertige Alkohole, sowie Alkylbenzolsulfonate mit 1 bis 3 Kohlenstoffatomen im Alkylrest dienen.As a solubilizer, such as dyes and perfume oils, for example, alkanolamines, Polyols such as ethylene glycol, propylene glycol, 1,2 glycerol and other mono- and polyvalent ones Alcohols, as well as alkylbenzenesulfonates having 1 to 3 carbon atoms in the alkyl radical serve.

Wichtig ist u.a. die Klarheit der Produkte, ein Absetzen von Phasen oder Inhaltsstoffen sowie ein trübes Aussehen ist in der Regel nicht erwünscht.Important is u.a. the clarity of the products, discontinuation of phases or ingredients and a dull appearance is usually not desirable.

Besondere Vorteile erhält man - insbesondere bei hoch tensidhaltigen Mischungen -, wenn man der Formulierung eine Zusammensetzung aus Na-Salzen der Adipin-, Bernstein- und Glutarsäure beimengt, wie sie z. B. unter dem Handelsnamen Sokalan® DSC erhältlich ist. Als besonders günstig hat sich hierbei der Einsatz von 0,1 bis 8 Gew.-%, bevorzugt 1 bis 6 Gew.-%, besonders bevorzugt 2,5 bis 5 Gew.-% erwiesen.Special advantages are obtained - especially for mixtures containing high levels of surfactants - when the formulation is a composition of Na salts of adipic, amber and glutaric adds as they are z. B. under the trade name Sokalan® DSC is available. Particularly advantageous here is the use of 0.1 to 8 wt .-%, preferably 1 to 6 wt .-%, more preferably 2.5 to 5 wt .-% proven.

Eine weitere günstige Komponente der erfindungsgemäßen Mittel sind Lösungsmittel, beispielsweise ein oder mehrere niedermolekulare Alkohole, z.B. Ethanol. Sie tragen zur Einarbeitung von Parfüm und Farbstoff bei, verhindern die Ausbildung flüssigkristalliner Phasen und haben Anteil an der Bildung klarer Produkte. Erfindungsgemäß können zwischen 0 und 12 Gew.-%, bevorzugt zwischen 3 und 10 Gew.-%, besonders bevorzugt zwischen 5 und 8 Gew.-%, Lösungsmittel enthalten sein.Another favorable component of the agents according to the invention are solvents, for example, one or more low molecular weight alcohols, e.g. Ethanol. They contribute to Incorporation of perfume and dye at, prevent the formation of liquid crystalline Phases and contribute to the formation of clear products. According to the invention between 0 and 12% by weight, preferably between 3 and 10% by weight, more preferably between 5 and 8% by weight of solvent.

Neben den bisher erwähnten Inhaltsstoffen können noch weitere, in Handgeschirrspülmitteln übliche, Inhaltstoffe, wie Entschäumer (z.B. Siliconöle, Paraffinöle oder Mineralöle), Strukturierungsmittel, Parfumstoffe, Farbstoffe, Korrosionsinhibitoren und Konservierungsmittel in Mengen bis zu 5 Gew.-% enthalten sein. In addition to the ingredients mentioned so far, more, in hand dishwashing detergents customary ingredients, such as defoamers (for example, silicone oils, paraffin oils or mineral oils), Structurants, perfumes, dyes, corrosion inhibitors and preservatives be contained in amounts up to 5 wt .-%.

BeispieleExamples Beispiel 1example 1

Die antibakterielle Wirkung des erfindungsgemäßen Handgeschirrspülmittels sei beispielhaft an folgenden Rezepturen verdeutlicht (in den Tabellen der Beispiele 1 und 2 steht die Einheit % für Gew.-%). Die angegebenen pH-Werte wurden mit Citronensäure eingestellt. Grundrezeptur 31,5 Gew.-% C12-14-Fettalkoholethersulfat (1,3 EO) 3,0 Gew.-% C8-16-Alkylpolyglucosid dp1,4 5,0 Gew.-% Cocoamidopropylbetain 3,5 Gew.-% Dicarbonsäuregemisch (Sokalan®-DSC-Na) x Gew.-% Ethanol y Gew.-% Wirkstoff ad 100,0 Gew.-% Wasser Rezeptur 1 2 3 4 5 6 7 Wirkstoff 2,0 % Benzoesäure 3,0 % Milchsäure 0,3% Germall® 115 + 0,2 % Salicylsäure 0,1 % Triclosan (Irgasan® DP300) 0,2 % Chloramin T (Halamid) 3,0% Benzylalkohol 0,5% Imidazolinidyl - Harnstoff (Germall® 115) Ethanol 7,0 % 7,2 % 7,5% 7,5% 7,5% 6,5% 7,5% pH-Wert 5,15 5,1 5,2 6,8 7,0 6,8 6,7 logarithm. Reduktionsrate Salmonella enteritidis >5,6 4,1 2,7 0,2 - 0,2 0,7 0,07 The antibacterial effect of the hand dishwashing detergent according to the invention is illustrated by way of example in the following formulations (in the tables of Examples 1 and 2, the unit% stands for% by weight). The indicated pH values were adjusted with citric acid. basic formulation 31.5 Wt% C 12-14 fatty alcohol ether sulfate (1.3 EO) 3.0 Wt% C 8-16 alkyl polyglucoside d p 1.4 5.0 Wt% cocoamidopropyl betaine 3.5 % By weight of dicarboxylic acid mixture (Sokalan®-DSC-Na) x Wt .-% ethanol y Wt .-% active ingredient ad 100.0 Wt .-% water recipe 1 2 3 4 5 6 7 active substance 2.0% benzoic acid 3.0% lactic acid 0.3% Germall® 115 + 0.2% salicylic acid 0.1% triclosan (Irgasan® DP300) 0.2% chloramine T (halamid) 3.0% benzyl alcohol 0.5% imidazolinidyl urea (Germall® 115) ethanol 7.0% 7.2% 7.5% 7.5% 7.5% 6.5% 7.5% PH value 5.15 5.1 5.2 6.8 7.0 6.8 6.7 logarithm. reduction rate Salmonella enteritidis > 5.6 4.1 2.7 0.2 - 0.2 0.7 0.07

Beispiel 2Example 2

Die antivirale Wirkung des erfindungsgemäßen Handgeschirrspülmittels sei weiterhin an den vollständig gegen Herpes-Viren wirksamen Rezepturen 8 und 9 auf der Basis der folgenden Grundrezeptur exemplifiziert. Zusätzlich enthielten beide Rezepturen geringe Mengen an Farb- und Duftstoff. Mit Citronensäure wurde jeweils ein pH-Wert von 5.2 eingestellt. Grundrezeptur 31,5 Gew.-% C12-14-Fettalkoholethersulfat (1,3-EO) 5,0 Gew.-% C8-16-Atkylpolyglucosid dp1,4 3,0 Gew.-% Cocoamidopropylbetain 3,5 Gew.-% Dicarbonsäuregemisch (Sokalan®-DSC-Na) 6,5 Gew.-% Ethanol y Gew.-% Wirkstoff ad 100,0 Gew.-% Wasser Rezeptur 8 9 Wirkstoff 2,35% Natrium-Benzoat 1,75% Natrium-Benzoat + 1,50% Milchsäure logarithmisch Reduktionsfaktor Herpes-Virus Prüfkonz. 0,04 %ig bei 30°C >5,5 >5,5 Prüfkonz. 0,20 %ig bei 40°C nicht bestimmt >5,5 The antiviral effect of hand dishwashing detergent according to the invention is further exemplified in the formulations completely effective against herpes viruses 8 and 9 on the basis of the following basic formulation. In addition, both formulations contained small amounts of color and perfume. Citric acid was used to adjust the pH to 5.2. basic formulation 31.5 Wt% C 12-14 fatty alcohol ether sulfate (1,3-EO) 5.0 % By weight of C 8-16 -alkylpolyglucoside d p 1.4 3.0 Wt% cocoamidopropyl betaine 3.5 % By weight of dicarboxylic acid mixture (Sokalan®-DSC-Na) 6.5 Wt .-% ethanol y Wt .-% active ingredient ad 100.0 Wt .-% water recipe 8th 9 active substance 2.35% sodium benzoate 1.75% sodium benzoate + 1.50% lactic acid logarithmic reduction factor herpes virus Prüfkonz. 0.04% at 30 ° C > 5.5 > 5.5 Prüfkonz. 0.20% at 40 ° C not determined > 5.5

Die Prüfmethodik basierte auf der Richtlinie des Bundesgesundheitsamtes (BGA) und der Deutschen Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) zur Prüfung von chemischen Desinfektionsmitteln auf Wirksamkeit gegen Viren in der Fassung vom 1.9.1982 (Bundesgesundheitsblatt 1982, 25, Nr. 12, 397-398) mit den folgenden Abweichungen, daß

  • 1.) anstelle der dort vorgeschriebenen Prüfviren Herpes simplex-Virus, Stamm HV342 (Kultivierung auf den in der Richtlinie angegebenen Vero-Zellen) verwendet wurde,
  • 2.) anstelle der dort angegebenen Raumtemperatur die oben angegebenen Prüftemperaturen von 30 und 40°C zugrunde gelegt wurden und
  • 3.) abweichend von der Richtlinie auf eine zusätzliche Belastung des Testansatzes durch fötales Kälberserum verzichtet wurde.
    • The test methodology was based on the guidelines of the Federal Health Office (BGA) and the German Association for the Control of Viral Diseases (DVV) for the testing of chemical disinfectants for efficacy against viruses in the version of 1.9.1982 (Bundesgesundheitsblatt 1982, 25, No. 12, 397- 398) with the following differences:
  • 1.) instead of the test viruses prescribed herpes simplex virus, strain HV342 (cultivation on the Vero cells indicated in the guideline) was used,
  • 2.) instead of the room temperature specified there, the above-mentioned test temperatures of 30 and 40 ° C were used as basis and
  • 3.) deviating from the guideline, an additional burden of the test batch by fetal calf serum was dispensed with.

    • Die Einwirkzeit betrug jeweils 15 Minuten bei den in der Tabelle angegebenen Prüfkonzentrationen.The exposure time was 15 minutes at the test concentrations indicated in the table.

    Claims (14)

    1. Use of a composition comprising surfactant mixtures of anionic surfactants and/or nonionic surfactants and/or betaine surfactants and also one or more carboxylic acids and/or their salts with an antibacterial action as an antibacterial hand dish-washing detergent with an antiviral action against herpes viruses.
    2. Use according to Claim 1, characterized in that the composition has a pH of between 4.0 and 6.0.
    3. Use according to any of the preceding claims, characterized in that the surfactant mixtures comprise anionic and nonionic surfactants.
    4. Use according to Claim 3, characterized in that the surfactant mixtures additionally comprise betaine surfactants.
    5. Use according to Claim 3 or 4, characterized in that the composition comprises, as nonionic surfactant, alkylpolyglycosides, preferably alkylpolyglucosides.
    6. Use according to any of the preceding claims, characterized in that the composition comprises between 0.1 and 8% by weight of carboxylic acid and/or carboxylic acid salts.
    7. Use according to any of the preceding claims, characterized in that the composition comprises, as carboxylic acid, benzoic acid, lactic acid, salicylic acid, sorbic acid or their mixtures and/or their sodium, potassium, magnesium or calcium salts.
    8. Use according to any of the preceding claims, characterized in that the composition comprises, as antibacterial constituent, an active substance combination consisting of carboxylic acids and/or carboxylic acid salts and imidazolidinylurea.
    9. Use according to Claim 8, characterized in that the active substance combination comprises between 0.05 and 2% by weight of carboxylic acids and/or carboxylic acid salts and between 0.05 and 2% by weight of imidazolidinylurea.
    10. Use according to any of the preceding claims, characterized in that the composition comprises 0.4 to 50% by weight of surfactant mixture.
    11. Use according to any of the preceding claims, characterized in that the composition comprises (a) 0.2 to 39.8% by weight of anionic surfactants, preferably fatty alcohol ether sulphates and/or fatty alcohol sulphates, (b) 0.1 to 14.9% by weight of nonionic surfactants, preferably alkylpolyglucosides, and (c) 0.1 to 14.9% by weight of betaine surfactants, preferably alkylamidobetaines.
    12. Use according to any of the preceding claims, characterized in that the composition comprises, as further constituent, one or more dicarboxylic acids and/or their salts, alone or as a mixture, in amounts of 0.1 to 8% by weight.
    13. Use according to any of the preceding claims, characterized in that the composition comprises solvents, for example one or more low-molecular-weight alcohols, for example ethanol, in amounts of up to 12% by weight, preferably between 3 and 10% by weight.
    14. Use according to any of the preceding claims, characterized in that the composition comprises other constituents conventionally used in hand dish-washing detergents, such as UV stabilizers, antifoams, solvents, structuring agents, fragrances, colours, corrosion inhibitors and preservatives.
    EP98958927A 1997-12-05 1998-11-28 DISHWASHING DETERGENT WITH ANTIBACTERIAL and antiviral ACTION Expired - Lifetime EP1036146B1 (en)

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    DE19753982A DE19753982A1 (en) 1997-12-05 1997-12-05 Dishwashing liquid with an antibacterial effect
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    PCT/EP1998/007698 WO1999029815A1 (en) 1997-12-05 1998-11-28 Dishwashing detergent with antibacterial action

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    US11937602B2 (en) 2017-09-26 2024-03-26 Ecolab Usa Inc. Solid acid/anionic antimicrobial and virucidal compositions and uses thereof

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    ATE287940T1 (en) 2005-02-15
    WO1999029815A1 (en) 1999-06-17
    JP2001526301A (en) 2001-12-18
    ES2236963T3 (en) 2005-07-16
    DE19753982A1 (en) 1999-06-10
    EP1036146A1 (en) 2000-09-20
    DE59812520D1 (en) 2005-03-03

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