EP1017716A4 - Car receptors and related molecules and methods - Google Patents

Car receptors and related molecules and methods

Info

Publication number
EP1017716A4
EP1017716A4 EP98944876A EP98944876A EP1017716A4 EP 1017716 A4 EP1017716 A4 EP 1017716A4 EP 98944876 A EP98944876 A EP 98944876A EP 98944876 A EP98944876 A EP 98944876A EP 1017716 A4 EP1017716 A4 EP 1017716A4
Authority
EP
European Patent Office
Prior art keywords
methods
related molecules
car receptors
receptors
car
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98944876A
Other languages
German (de)
French (fr)
Other versions
EP1017716A1 (en
Inventor
David D Moore
Hueng-Sik Choi
Myriam I Baes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/934,388 external-priority patent/US6989242B1/en
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP1017716A1 publication Critical patent/EP1017716A1/en
Publication of EP1017716A4 publication Critical patent/EP1017716A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP98944876A 1997-09-19 1998-09-17 Car receptors and related molecules and methods Withdrawn EP1017716A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/934,388 US6989242B1 (en) 1992-02-26 1997-09-19 Car receptors and related molecules and methods
PCT/US1998/019365 WO1999015555A1 (en) 1997-09-19 1998-09-17 Car receptors and related molecules and methods
US934388 2001-08-21

Publications (2)

Publication Number Publication Date
EP1017716A1 EP1017716A1 (en) 2000-07-12
EP1017716A4 true EP1017716A4 (en) 2001-01-03

Family

ID=25465488

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98944876A Withdrawn EP1017716A4 (en) 1997-09-19 1998-09-17 Car receptors and related molecules and methods

Country Status (2)

Country Link
EP (1) EP1017716A4 (en)
WO (1) WO1999015555A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051045A2 (en) * 2000-01-13 2001-07-19 Tularik Inc. Modulators of the constitutive adrostane receptor (car): screening and treatment of hypercholesterolemia
JP2004503226A (en) * 2000-06-14 2004-02-05 デルタジェン　インコーポレイテッド Transgenic mouse containing nuclear hormone receptor gene disruption
CA2422921A1 (en) 2000-09-21 2002-03-28 David D. Moore Screening systems and methods for identifying modulators of xenobiotic metabolism
US7186879B2 (en) 2000-09-21 2007-03-06 Baylor College Of Medicine Screening systems and methods for identifying modulators of xenobiotic metabolism
EP1371661A1 (en) * 2002-06-13 2003-12-17 LION Bioscience AG Variants of the Constitutive Activated of Retinoid acid response receptor (CAR) in its ligand binding domain (LBD)
TWI654206B (en) 2013-03-16 2019-03-21 諾華公司 Treatment of cancer with a humanized anti-CD19 chimeric antigen receptor
SG10202109752XA (en) * 2014-04-07 2021-10-28 Novartis Ag Treatment of cancer using anti-cd19 chimeric antigen receptor
SG11201708191XA (en) 2015-04-08 2017-11-29 Novartis Ag Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998033819A1 (en) * 1997-01-30 1998-08-06 New York University Cellular receptors for subgroup c adenoviruses and group b coxsackieviruses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756448A (en) * 1992-02-26 1998-05-26 The General Hospital Corporation Constitute activator of retinoid (CAR) receptor polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998033819A1 (en) * 1997-01-30 1998-08-06 New York University Cellular receptors for subgroup c adenoviruses and group b coxsackieviruses

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BAES, MYRIAM ET AL.: "A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements", MOLECULAR AND CELLULAR BIOLOGY, vol. 14, no. 3, March 1994 (1994-03-01), pages 1544 - 1552, XP000613954 *
DATABASE EMBL [online] 22 July 1997 (1997-07-22), CHOI H.S. ET AL.: "Mus musculus orphan nuclear hormone receptor isoform mCAR1 mRNA, complete cds.", XP002152126, Database accession no. AF009327 *
HUENG-SIK CHOI ET AL.: "Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 38, 19 September 1997 (1997-09-19), MD US, pages 23565 - 23571, XP002152125 *
RICHARD P. TOMKO ET AL.: "HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 94, April 1997 (1997-04-01), WASHINGTON US, pages 3352 - 3356, XP002911143 *
See also references of WO9915555A1 *

Also Published As

Publication number Publication date
EP1017716A1 (en) 2000-07-12
WO1999015555A1 (en) 1999-04-01

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Legal Events

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