EP0996441A4 - Pharmaceutical compositions of arglabin and arglabin derivatives - Google Patents
Pharmaceutical compositions of arglabin and arglabin derivativesInfo
- Publication number
- EP0996441A4 EP0996441A4 EP98918509A EP98918509A EP0996441A4 EP 0996441 A4 EP0996441 A4 EP 0996441A4 EP 98918509 A EP98918509 A EP 98918509A EP 98918509 A EP98918509 A EP 98918509A EP 0996441 A4 EP0996441 A4 EP 0996441A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- arglabin
- pharmaceutical compositions
- derivatives
- arglabin derivatives
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KZ973971 | 1997-04-23 | ||
KZ970397 | 1997-04-26 | ||
US5168197P | 1997-07-03 | 1997-07-03 | |
US51681P | 1997-07-03 | ||
US93422897A | 1997-09-19 | 1997-09-19 | |
US08/934,229 US5902809A (en) | 1997-07-03 | 1997-09-19 | Arglabin compounds and therapeutic uses thereof |
US08/934,471 US6693127B1 (en) | 1997-07-03 | 1997-09-19 | Pharmaceutical compositions of arglabin and arglabin derivatives |
US934471 | 1997-09-19 | ||
US934229 | 1997-09-19 | ||
PCT/US1998/007989 WO1998048789A1 (en) | 1997-04-26 | 1998-04-22 | Pharmaceutical compositions of arglabin and arglabin derivatives |
US934228 | 2001-08-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0996441A1 EP0996441A1 (en) | 2000-05-03 |
EP0996441A4 true EP0996441A4 (en) | 2002-08-07 |
Family
ID=27532391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98918509A Withdrawn EP0996441A4 (en) | 1997-04-26 | 1998-04-22 | Pharmaceutical compositions of arglabin and arglabin derivatives |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0996441A4 (en) |
JP (1) | JP3507511B2 (en) |
AU (1) | AU7141898A (en) |
CA (1) | CA2287318A1 (en) |
WO (1) | WO1998048789A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994388A (en) | 1997-03-18 | 1999-11-30 | The Children's Medical Center Corporation | Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis |
US6051565A (en) * | 1997-04-26 | 2000-04-18 | International Phytochemistry Research Labs, Ltd. | Farnesyl-protein transferase inhibitors |
GB9809889D0 (en) * | 1998-05-11 | 1998-07-08 | Univ Strathclyde | Prevention of restenosis |
WO1999064003A1 (en) * | 1998-06-09 | 1999-12-16 | Tovarischestvo S Ogranichennoi Otvetstvennostju 'tabifarm' | Method of treatment of patients with initial liver cancer |
CA2356438A1 (en) * | 2001-09-05 | 2003-03-05 | Andre Pichette | Use of terpenes and derivatives as potentiators of antitumor agents in the treatment of cancers |
US7678904B2 (en) | 2003-07-11 | 2010-03-16 | University Of Kentucky | Use of parthenolide derivatives as antileukemic and cytotoxic agents |
AU2004257696B2 (en) * | 2003-07-11 | 2010-09-16 | University Of Kentucky Research Foundation | Use of parthenolide derivatives as antileukemic and cytotoxic agents |
CN102372723B (en) * | 2010-08-19 | 2014-03-26 | 石药集团中奇制药技术(石家庄)有限公司 | Method for extracting arglabin from artemisia myriantha |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995006476A1 (en) * | 1993-09-03 | 1995-03-09 | Trustees Of Boston University | Methods and compositions for treating neoplastic disorders |
-
1998
- 1998-04-22 AU AU71418/98A patent/AU7141898A/en not_active Abandoned
- 1998-04-22 EP EP98918509A patent/EP0996441A4/en not_active Withdrawn
- 1998-04-22 WO PCT/US1998/007989 patent/WO1998048789A1/en not_active Application Discontinuation
- 1998-04-22 JP JP54708898A patent/JP3507511B2/en not_active Expired - Fee Related
- 1998-04-22 CA CA002287318A patent/CA2287318A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995006476A1 (en) * | 1993-09-03 | 1995-03-09 | Trustees Of Boston University | Methods and compositions for treating neoplastic disorders |
Non-Patent Citations (2)
Title |
---|
BOTTEX-GAUTHIER C ET AL: "IN VITRO BIOLOGICAL ACTIVITIES OF ARGLABIN, A SESQUITERPENE LACTONE FROM THE CHINESE HERB Artemisi myriantha WALL. (ASTERACEAE)", BIOTECHNOLOGY THERAPEUTICS, MARCEL DEKKER, NEW YORK, NY, US, vol. 4, no. 1/2, 1993, pages 77 - 98, XP002114696, ISSN: 0898-2848 * |
See also references of WO9848789A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0996441A1 (en) | 2000-05-03 |
JP3507511B2 (en) | 2004-03-15 |
AU7141898A (en) | 1998-11-24 |
JP2002509532A (en) | 2002-03-26 |
WO1998048789A1 (en) | 1998-11-05 |
CA2287318A1 (en) | 1998-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19991126 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20020625 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7A 61K 31/34 A, 7A 61K 31/70 B, 7A 61K 31/56 B, 7A 61K 31/505 B, 7A 61K 31/35 B, 7A 61K 31/28 B, 7A 61K 31/365 B, 7A 61K 31/475 B, 7C 07D 307/93 B, 7C 07D 493/04 B, 7C 07D 493/10 B, 7C 07D 493/20 B |
|
17Q | First examination report despatched |
Effective date: 20030929 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: ADEKENOV, SERGAZY M. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060124 |