EP0977764A4 - Procede de production de fragments de saccharide - Google Patents

Procede de production de fragments de saccharide

Info

Publication number
EP0977764A4
EP0977764A4 EP98914310A EP98914310A EP0977764A4 EP 0977764 A4 EP0977764 A4 EP 0977764A4 EP 98914310 A EP98914310 A EP 98914310A EP 98914310 A EP98914310 A EP 98914310A EP 0977764 A4 EP0977764 A4 EP 0977764A4
Authority
EP
European Patent Office
Prior art keywords
saccharide fragments
generating
generating saccharide
fragments
saccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98914310A
Other languages
German (de)
English (en)
Other versions
EP0977764A1 (fr
Inventor
Ying Wang
Rawle I Hollingsworth
Dennis L Kasper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of EP0977764A1 publication Critical patent/EP0977764A1/fr
Publication of EP0977764A4 publication Critical patent/EP0977764A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
EP98914310A 1997-03-26 1998-03-26 Procede de production de fragments de saccharide Withdrawn EP0977764A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4241697P 1997-03-26 1997-03-26
US42416P 1997-03-26
PCT/US1998/005889 WO1998042718A1 (fr) 1997-03-26 1998-03-26 Procede de production de fragments de saccharide

Publications (2)

Publication Number Publication Date
EP0977764A1 EP0977764A1 (fr) 2000-02-09
EP0977764A4 true EP0977764A4 (fr) 2001-04-11

Family

ID=21921821

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98914310A Withdrawn EP0977764A4 (fr) 1997-03-26 1998-03-26 Procede de production de fragments de saccharide

Country Status (5)

Country Link
US (2) US6027733A (fr)
EP (1) EP0977764A4 (fr)
JP (1) JP2001519817A (fr)
CA (1) CA2284606A1 (fr)
WO (1) WO1998042718A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998042718A1 (fr) * 1997-03-26 1998-10-01 The Brigham And Women's Hospital, Inc. Procede de production de fragments de saccharide
US6692739B1 (en) * 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
US6492897B1 (en) 2000-08-04 2002-12-10 Richard A. Mowery, Jr. System for coupling wireless signals to and from a power transmission line communication system
CA2461906A1 (fr) * 2001-09-27 2003-04-10 Heppe Gmbh Biotechnologische Systeme Und Materialien Procede et dispositif pour produire des oligomeres modifies a base de polysaccharides
DK1490409T3 (da) * 2002-03-26 2009-03-23 Novartis Vaccines & Diagnostic Modificerede saccharider med forbedret stabilitet i vand
US20040096461A1 (en) * 2002-07-30 2004-05-20 Baxter Healthcare Corporation Chimeric multivalent polysaccharide conjugate vaccines
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
US20090136547A1 (en) * 2005-08-24 2009-05-28 Novartis Vaccines And Diagnostics Srl Zwitterionization of capsular saccharides
GB0605757D0 (en) 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
US20090124573A1 (en) 2007-11-09 2009-05-14 Sarkis Mazmanian Immunomodulating compounds and related compositions and methods
WO2010110931A2 (fr) 2009-03-23 2010-09-30 The Brigham And Women's Hospital, Inc. Vaccins glycoconjugués
MX338753B (es) * 2009-09-30 2016-04-29 Novartis Ag Conjugacion de polisacaridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus.
EP3199177A1 (fr) * 2009-10-30 2017-08-02 GlaxoSmithKline Biologicals S.A. Purification de saccharides capsulaires de staphylococcus aureus de type 5 et de type 8
ES2694100T3 (es) 2010-04-07 2018-12-18 California Institute Of Technology Vehículo para distribuir un compuesto en una membrana mucosa y composiciones, procedimientos y sistemas relacionados
US20110287048A1 (en) 2010-05-20 2011-11-24 Round June L Antigen Specific Tregs and related compositions, methods and systems
GB201101665D0 (en) 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions
US9539281B2 (en) 2011-07-12 2017-01-10 The Brigham And Women's Hospital, Inc. Lipid-containing PSA compositions, methods of isolation and methods of use thereof
ES2773954T3 (es) 2012-10-03 2020-07-15 Glaxosmithkline Biologicals Sa Composición inmunogénica
EP2994161B1 (fr) 2013-05-10 2020-10-28 California Institute of Technology Prévention et traitement probiotiques du cancer du côlon
EP2942396A1 (fr) 2014-05-07 2015-11-11 Novartis AG Polysaccharides produits par mutants CPSC
WO2016201342A1 (fr) 2015-06-10 2016-12-15 California Institute Of Technology Traitement du sepsis, compositions, méthodes et systèmes associés
JP6918365B2 (ja) 2015-08-19 2021-08-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 脂質化ｐｓａ組成物および方法
EP3439704A1 (fr) 2016-04-05 2019-02-13 GSK Vaccines S.r.l. Compositions immunogènes
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use
AU2017385354B2 (en) * 2016-12-30 2021-06-03 Green Valley (Shanghai) Pharmaceuticals Co., Ltd. Method of degrading polysaccharide using ozone

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316982A (en) * 1979-04-27 1982-02-23 Hoechst Aktiengesellschaft Process for reducing the viscosity of cellulose ethers by means of ozone and application thereof
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
EP0371414A2 (fr) * 1988-11-27 1990-06-06 BEHRINGWERKE Aktiengesellschaft Glycosphingolipides avec un groupe couplant dans la partie sphingolipide, leur préparation et utilisation
EP0382576A1 (fr) * 1989-02-10 1990-08-16 Alko Ltd. Hydrolysat d'un dérivé de cellulose et ses fractions
EP0497524A2 (fr) * 1991-01-28 1992-08-05 Merck & Co. Inc. Antigènes polysaccharadiques à partir de Streptococcus pneumoniae

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723506A (en) * 1971-08-11 1973-03-27 Univ Sherbrooke Oxidation of sugars
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
WO1998042718A1 (fr) * 1997-03-26 1998-10-01 The Brigham And Women's Hospital, Inc. Procede de production de fragments de saccharide
US5929049A (en) * 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316982A (en) * 1979-04-27 1982-02-23 Hoechst Aktiengesellschaft Process for reducing the viscosity of cellulose ethers by means of ozone and application thereof
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
EP0371414A2 (fr) * 1988-11-27 1990-06-06 BEHRINGWERKE Aktiengesellschaft Glycosphingolipides avec un groupe couplant dans la partie sphingolipide, leur préparation et utilisation
EP0382576A1 (fr) * 1989-02-10 1990-08-16 Alko Ltd. Hydrolysat d'un dérivé de cellulose et ses fractions
EP0497524A2 (fr) * 1991-01-28 1992-08-05 Merck & Co. Inc. Antigènes polysaccharadiques à partir de Streptococcus pneumoniae

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9842718A1 *
ZHANG, Y. ET AL.: "Degradation of wood polysaccharide model compounds during ozone treatment", J. PULP PAP. SCI., vol. 23, no. 1, 1997, pages J23 - J27, XP000973103 *

Also Published As

Publication number Publication date
JP2001519817A (ja) 2001-10-23
EP0977764A1 (fr) 2000-02-09
US6274144B1 (en) 2001-08-14
CA2284606A1 (fr) 1998-10-01
WO1998042718A1 (fr) 1998-10-01
US6027733A (en) 2000-02-22

Similar Documents

Publication Publication Date Title
EP0977764A4 (fr) Procede de production de fragments de saccharide
PL328974A1 (en) Doketaxel synthesising method
HUP0000911A3 (en) Refuse-treatment method
HUP0004031A2 (en) Method for producing triazolinthion derivatives
GB2345063B (en) Method
GB9721603D0 (en) Method
GB9706282D0 (en) Method
GB2326898B (en) One-trip window-milling method
GB9700320D0 (en) Method
HUP0003957A3 (en) Method for producing calcium borate method for producing calcium borate
GB9713283D0 (en) Method for preparing aminoalkoxysiloxanes
AU6132598A (en) Method for generating curves
HUP0100453A3 (en) Method for producing isoureas
GB9707744D0 (en) Method
GB9717652D0 (en) Method
HUP0001596A3 (en) Method for producing 5-aminomethyl-2-chloropyridines
IL134507A0 (en) Method for preparing oxazaphosphorin-2-amines
PL341657A1 (en) Deparaffining method
HUP0003768A3 (en) Method for producing thiochloroformates
IL132968A0 (en) Method for producing 2-cyclododecyl-1-propanol
IL136698A0 (en) Method for producing chlorobenzoxazolene
MD810F1 (en) Process for modified ionites obtaining
HUP9701196A3 (en) Method for producing orthopaedic foot-supports
IL134549A0 (en) Method for producing substituted-2- nitroguanidine derivatives
GB9709811D0 (en) Method

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19991026

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7C 07H 15/04 A, 7A 61K 39/02 B, 7A 61K 39/385 B

A4 Supplementary search report drawn up and despatched

Effective date: 20010222

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20030114

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20030725