EP0963319A1 - Verfahren zur steuerung der luftgeschwindigkeit in einem sterilisiertunnel während dessen aufheizphase - Google Patents
Verfahren zur steuerung der luftgeschwindigkeit in einem sterilisiertunnel während dessen aufheizphaseInfo
- Publication number
- EP0963319A1 EP0963319A1 EP98905254A EP98905254A EP0963319A1 EP 0963319 A1 EP0963319 A1 EP 0963319A1 EP 98905254 A EP98905254 A EP 98905254A EP 98905254 A EP98905254 A EP 98905254A EP 0963319 A1 EP0963319 A1 EP 0963319A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- tunnel
- speed
- heating
- air
- during
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/025—Packaging in aseptic tunnels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
- B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases
Definitions
- the invention is based on a method for controlling the air speed in a sterilization tunnel during its heating phase according to the preamble of claim 1.
- Such sterilization tunnels are used in particular for the sterilization of ampoules, vials or the like in the pharmaceutical packaging industry.
- Filter elements for cleaning the air circulated in the sterilization tunnel are arranged in the sterilization tunnels. So that these filter elements are not damaged on the one hand, and on the other hand have their optimal cleaning effect and no particles are torn out of the filter elements, it is necessary that the filter elements are flowed through at a certain air speed.
- speed measuring devices are used, which are coupled via a control device to a fan, the speed of which corresponds to the measured air speed. speed is changed.
- a disadvantage of the known method is that the air speed measuring devices have only a short service life due to the high temperatures achieved in the sterilization tunnel, for example 350 degrees Celsius at the end of the heating phase.
- the known sterilization tunnels are complex due to the additional measuring devices and control devices. Measurement errors, for example due to soiling of the measuring devices, are also not recognized, so that the sterilization process cannot be carried out safely. This is because the speed of the fan is also set incorrectly due to an incorrectly measured air speed, so that the filter elements do not work optimally.
- the fan speed constant so that it is 0.5 meters per second, for example at 350 degrees Celsius.
- an air speed of approx. 0.9 meters per second must be set when the sterilization tunnel is cold.
- the increased air speed set first automatically reduces to the air speed required for sterilization operation due to the heating of the air.
- the filter elements arranged in the suction area and in the blow-out area of the fan are heavily loaded by the increased air speed and thus a large amount of air.
- the fan must be designed for the large amount of air accordingly strong. This method therefore also requires a relatively high outlay in terms of device technology.
- the method according to the invention for controlling the air speed in a sterilization tunnel during its opening Heating phase with the characterizing features of claim 1 has the advantage that it works without additional air speed measuring devices and at the same time is sufficiently precise, the filter elements always working optimally. It follows that the blower or the filter does not have to be reinforced and that the sterilization process works safely. According to the invention, this is achieved in that the fan speed is changed in accordance with a predetermined function curve.
- the sterilizing tunnel 10 shown in FIG. 1 is used to treat pharmaceutical containers 11 such as ampoules, vials or the like before they are filled. For this it is necessary to sterilize the non-sterile delivered containers 11. This takes place in the sterilization tunnel 10 in that the previously wet-cleaned containers 11 are introduced into the sterilization tunnel 10, in which they are first preheated from room temperature to approx . The containers 11 then reach the area of the hot part 13 shown in FIG. 1, in which the containers 11 are further heated to approximately 350 degrees Celsius, the germs or the like being killed off by the heating and a stream of hot air. Finally, the containers 11 are cooled again to room temperature in a cooling region, also not shown, from where they are passed on to a filling system.
- the sterilizing tunnel 10 has in the heating part 13 a tunnel-shaped area 14 with lateral boundary walls 15, in which the containers 11 are arranged upright on the conveyor belt 12.
- a suction filter 17 is integrated in an opening in a housing wall 16 of the sterilization tunnel 10 and opens into a channel 18 arranged laterally from the region 14 and separated by means of the one boundary wall 15.
- a heating device 20 is also provided, which heats the sucked-in air to the required sterilizing temperature.
- the air From the heating device 20, the air enters a speed-controllable fan 21 arranged above the area 14, which draws in the air and the air heated in the heating device 20 via a sterile filter 23 arranged directly above the area 14 as a hot air flow directed vertically from top to bottom Area 14 conducts.
- a grid floor 24 is provided below which an exhaust air region 26 is arranged.
- the exhaust air area 26 opens into the channel 18 and, on the other hand, part of the moist air is sucked off via a second fan 27 in the inlet area of the sterilization tunnel 10.
- a temperature sensor 29 is arranged above the containers 11 in a boundary wall 15 and is connected to the control device of the sterilizing tunnel 10, not shown.
- the sterilization tunnel 10 described above works as follows: During the commissioning of the sterilization tunnel 10, the air located in the area 14 is heated by the heating device 20 from room temperature to the required sterilization temperature, for example 350 degrees Celsius. The air is circulated with the aid of the fan 21. In order to ensure the optimal function of the sterile filter 23 during sterilization, a flow speed of, for example, 0.5 m / s is required, for which purpose a certain fan speed is necessary.
- this fan speed would correspond to a flow velocity of the air of approximately 0.9 m / s, which should be avoided so that no particles are torn out of the sterile filter 23.
- the fan speed is determined in advance, which corresponds to a flow speed of 0.5 m / s at room temperature.
- This fan speed which is known to the control device of the sterilization tunnel 10 as the input value or start value, is below the fan speed required at 350 degrees Celsius for the same air flow rate.
- the control device During the heating-up phase of the sterilizing tunnel 10, the control device now steadily increases the fan speed, so that during the heating-up phase there is almost the same flow velocity in the area 14 over the entire temperature range.
- the fan speed is increased continuously or step by step over the known or previously determined heating time.
- the signal supplied by the temperature sensor 29 to the control device as an input value is preferably used, on the basis of which the control device increases the speed, for example via a linear relationship with increasing temperature.
- the relationship between the temperature and the required fan speeds can, however, also take place on the basis of a more complex functional relationship stored in the control device if, for example, flow resistances above the air temperature do not change linearly.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Ventilation (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19709067A DE19709067A1 (de) | 1997-03-06 | 1997-03-06 | Verfahren zur Steuerung der Luftgeschwindigkeit in einem Sterilisierungstunnel während der Aufheizphase |
DE19709067 | 1997-03-06 | ||
PCT/DE1998/000106 WO1998039216A1 (de) | 1997-03-06 | 1998-01-14 | Verfahren zur steuerung der luftgeschwindigkeit in einem sterilisiertunnel während dessen aufheizphase |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0963319A1 true EP0963319A1 (de) | 1999-12-15 |
EP0963319B1 EP0963319B1 (de) | 2003-08-06 |
Family
ID=7822375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98905254A Expired - Lifetime EP0963319B1 (de) | 1997-03-06 | 1998-01-14 | Verfahren zur steuerung der luftgeschwindigkeit in einem sterilisiertunnel während dessen aufheizphase |
Country Status (6)
Country | Link |
---|---|
US (1) | US6383449B1 (de) |
EP (1) | EP0963319B1 (de) |
JP (1) | JP4198194B2 (de) |
CN (1) | CN1163382C (de) |
DE (2) | DE19709067A1 (de) |
WO (1) | WO1998039216A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8221678B2 (en) * | 2002-02-20 | 2012-07-17 | Hedman David E | System and process for removing or treating harmful biological and organic substances within an enclosure |
US8256135B2 (en) * | 1999-05-28 | 2012-09-04 | Thermapure, Inc. | Method for removing or treating harmful biological and chemical substances within structures and enclosures |
US20040028583A1 (en) * | 2001-12-07 | 2004-02-12 | Hedman David E. | Portable decontamination unit useful in destroying harmful biological agents in contaminated objects |
US20110064607A1 (en) * | 1999-05-28 | 2011-03-17 | Thermapure, Inc. | Method for removing or treating harmful biological organisms and chemical substances |
US8272143B1 (en) | 2002-02-20 | 2012-09-25 | David Hedman | System and process for removing or treating harmful biological and organic substances within structures and enclosures |
US6612067B2 (en) * | 2001-05-16 | 2003-09-02 | Topp Construction Services, Inc. | Apparatus for and method of eradicating pests |
SE524496C2 (sv) * | 2002-12-13 | 2004-08-17 | Tetra Laval Holdings & Finance | Styrning av steriliseringsanordning |
SE524497C2 (sv) * | 2002-12-13 | 2004-08-17 | Tetra Laval Holdings & Finance | Steriliseringsanordning |
FR2882341B1 (fr) * | 2005-02-23 | 2009-11-20 | Serac Group | Installation de conditionnement aseptique a zones tampon aseptiques |
US7150627B2 (en) * | 2005-04-30 | 2006-12-19 | Siddhartha Gaur | Transported material heating with controlled atmosphere |
US7708960B2 (en) * | 2006-03-31 | 2010-05-04 | Spx Corporation | Dry heat convection sterilization system |
US20110064605A1 (en) * | 2006-07-05 | 2011-03-17 | Thermapure, Inc. | Method for treating an object contaminated with harmful biological organisms or chemical substances utilizing electromagnetic waves |
PL2485772T3 (pl) * | 2009-10-09 | 2015-02-27 | Sanofi Aventis Deutschland | Aparat sterylizacyjny oraz sposób sterowania aparatem sterylizacyjnym |
US9310132B1 (en) | 2012-02-08 | 2016-04-12 | Carbonyx, Inc. | Replaceable insulation roof for industrial oven |
DE102013102516A1 (de) * | 2013-03-13 | 2014-09-18 | Krones Ag | Vorrichtung sowie Verfahren zur Behandlung mindestens eines Behälters |
ITUB20160694A1 (it) * | 2016-02-12 | 2017-08-12 | Ima Spa | Gruppo di sterilizzazione e depirogenazione di contenitori |
CN105910409A (zh) * | 2016-04-29 | 2016-08-31 | 芜湖杨燕制药有限公司 | 注射液安瓿的杀菌干燥机 |
US11928534B2 (en) * | 2022-05-17 | 2024-03-12 | Print Management Partners, Inc. | Method of using an RFID label on a high-temperature product |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4077567A (en) * | 1976-06-18 | 1978-03-07 | Universal Pneumatic Controls, Inc. | Pneumatic temperature reset differential pressure controller |
DE2631352C3 (de) * | 1976-07-13 | 1983-02-17 | Bayer Ag, 5090 Leverkusen | Verfahren zur partikelarmen Sterilisation |
AT348685B (de) * | 1977-04-01 | 1979-02-26 | Ver Edelstahlwerke Ag | Sterilisierapparat fuer in behaelter abgefuellte infusionsloesungen od.dgl. |
US4729207A (en) * | 1986-09-17 | 1988-03-08 | Carrier Corporation | Excess air control with dual pressure switches |
DE3734830A1 (de) * | 1987-10-14 | 1989-04-27 | Gilowy Hans Maschf | Verfahren zur sterilisation von temperaturbelastbaren behaeltern unter reinraumbedingungen |
FR2661759B1 (fr) * | 1990-05-07 | 1992-08-28 | Sari | Procede de reglage de debit dans un dispositif de soufflage d'air et dispositif mettant en óoeuvre le procede. |
AT394909B (de) * | 1990-06-01 | 1992-07-27 | Vaillant Gmbh | Einrichtung zur kontinuierlichen ueberwachung eines variablen luftstromes |
US5022165A (en) * | 1990-06-29 | 1991-06-11 | The West Company, Incorporated | Sterilization tunnel |
DE4131258A1 (de) * | 1991-09-17 | 1992-05-07 | Siedler Torsten | Temperatur- und stroemungsregelungsvorrichtung im sterilisierapparat |
DE4217054A1 (de) * | 1992-05-22 | 1993-11-25 | Bausch & Stroebel Maschf | Sterilisiertunnel |
US5472141A (en) * | 1992-12-01 | 1995-12-05 | Combustion Concepts, Inc. | High efficiency gas furnace |
-
1997
- 1997-03-06 DE DE19709067A patent/DE19709067A1/de not_active Ceased
-
1998
- 1998-01-14 CN CNB988030675A patent/CN1163382C/zh not_active Expired - Fee Related
- 1998-01-14 EP EP98905254A patent/EP0963319B1/de not_active Expired - Lifetime
- 1998-01-14 WO PCT/DE1998/000106 patent/WO1998039216A1/de active IP Right Grant
- 1998-01-14 US US09/341,559 patent/US6383449B1/en not_active Expired - Fee Related
- 1998-01-14 JP JP53803398A patent/JP4198194B2/ja not_active Expired - Fee Related
- 1998-01-14 DE DE59809211T patent/DE59809211D1/de not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
See references of WO9839216A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0963319B1 (de) | 2003-08-06 |
JP2001513736A (ja) | 2001-09-04 |
CN1249721A (zh) | 2000-04-05 |
DE19709067A1 (de) | 1998-09-17 |
JP4198194B2 (ja) | 2008-12-17 |
CN1163382C (zh) | 2004-08-25 |
DE59809211D1 (de) | 2003-09-11 |
US6383449B1 (en) | 2002-05-07 |
WO1998039216A1 (de) | 1998-09-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0963319B1 (de) | Verfahren zur steuerung der luftgeschwindigkeit in einem sterilisiertunnel während dessen aufheizphase | |
DE60307890T2 (de) | Steuerung für sterilisationsvorrichtung und verfahren | |
EP0427055B1 (de) | Verfahren und Vorrichtung zur Sterilisation einer medizinischen Baugruppe | |
EP2049275B1 (de) | Verfahren zur sterilisation von reinräumen für die behandlung und/oder das füllen und verschliessen von behältern | |
EP0312022B1 (de) | Verfahren zur Sterilisation von temperaturbelastbaren Behältern unter Reinraumbedingungen | |
EP2778114B1 (de) | Vorrichtung sowie Verfahren zur Behandlung mindestens eines Behälters | |
DE102006060713B3 (de) | Sicherheitswerkbank und Verfahren zum Kalibrieren derselben | |
CH664892A5 (de) | Inkubator. | |
EP1450867B1 (de) | Sterilisiertunnel für pharmazeutische behältnisse | |
EP2152325A1 (de) | Verfahren zum sterilisieren von behältern | |
DE2631352C3 (de) | Verfahren zur partikelarmen Sterilisation | |
EP2562240A1 (de) | Laboratoriums-Brutschrank mit verbesserter Innenraum-Befeuchtung | |
EP0582238B1 (de) | Gerät für die Wärmebehandlung von Nahrungsmitteln | |
DE2702669A1 (de) | Verfahren und vorrichtung zur behandlung von gegenstaenden in einer autoklavenkammer | |
WO2005113169A1 (de) | Verfahren und apparatur für den phasenwechsel in einem isolator | |
EP2817033B1 (de) | Verfahren und vorrichtung zur gassterilisation von erzeugnissen bei dem die prozessgase vor einleiten in die sterilisationskammer durch einen mischer ohne bewegliche teile homogenisiert werden | |
DE3321195C2 (de) | ||
EP0845234B2 (de) | Vorrichtung und Verfahren zur Regelung des Feuchtigkeitsgehaltes in einer Kochvorrichtung | |
WO2010022819A1 (de) | Verfahren und vorrichtung zur sterilisierung von behältern | |
DE1936865C3 (de) | Heißlufttemper- und -Sterilisierapparat | |
EP3244934A1 (de) | Dekontaminationsanordnung | |
DE2112375B2 (de) | Vorrichtung zum Sterilisieren von Gegenständen | |
DE4131258A1 (de) | Temperatur- und stroemungsregelungsvorrichtung im sterilisierapparat | |
EP0657177B1 (de) | Vorrichtung zum Testen und Kontrollieren von nach dem Vakuumverfahren arbeitenden Dampfsterilisatoren | |
WO2005084835A1 (de) | Anordnung zur luftführung und druckregelung in einem isolator mit einer gegen die äussere umgebung abgeschirmten arbeitskammer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19991006 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB IT |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Designated state(s): DE FR GB IT |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REF | Corresponds to: |
Ref document number: 59809211 Country of ref document: DE Date of ref document: 20030911 Kind code of ref document: P |
|
GBT | Gb: translation of ep patent filed (gb section 77(6)(a)/1977) | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20031231 Year of fee payment: 7 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20040122 Year of fee payment: 7 |
|
ET | Fr: translation filed | ||
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20040507 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050114 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20050114 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050930 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20150324 Year of fee payment: 18 Ref country code: IT Payment date: 20150123 Year of fee payment: 18 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 59809211 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160802 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160114 |