EP0892639A4 - Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists - Google Patents

Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists

Info

Publication number
EP0892639A4
EP0892639A4 EP97905640A EP97905640A EP0892639A4 EP 0892639 A4 EP0892639 A4 EP 0892639A4 EP 97905640 A EP97905640 A EP 97905640A EP 97905640 A EP97905640 A EP 97905640A EP 0892639 A4 EP0892639 A4 EP 0892639A4
Authority
EP
European Patent Office
Prior art keywords
agonists
isomers
optically pure
uterine contractions
adrenergic beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP97905640A
Other languages
German (de)
French (fr)
Other versions
EP0892639A1 (en
Inventor
E Charles Pesterfield Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAVOR EVELYN
Original Assignee
SAVOR EVELYN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/592,988 external-priority patent/US5708036A/en
Application filed by SAVOR EVELYN filed Critical SAVOR EVELYN
Publication of EP0892639A1 publication Critical patent/EP0892639A1/en
Publication of EP0892639A4 publication Critical patent/EP0892639A4/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP97905640A 1996-01-29 1997-01-28 Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists Ceased EP0892639A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/592,988 US5708036A (en) 1996-01-29 1996-01-29 Method of treating premature uterine contractions using the optically active R(-)-isomer of albuterol
US592988 1996-01-29
US2299596P 1996-08-02 1996-08-02
US22995P 1996-08-02
PCT/US1997/001342 WO1997026871A1 (en) 1996-01-29 1997-01-28 Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists

Publications (2)

Publication Number Publication Date
EP0892639A1 EP0892639A1 (en) 1999-01-27
EP0892639A4 true EP0892639A4 (en) 1999-06-09

Family

ID=26696599

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97905640A Ceased EP0892639A4 (en) 1996-01-29 1997-01-28 Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists

Country Status (4)

Country Link
EP (1) EP0892639A4 (en)
AU (1) AU2247997A (en)
CA (1) CA2247953A1 (en)
WO (1) WO1997026871A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527545A (en) * 1997-04-30 2001-12-25 ブリッジ ファーマ,インコーポレーテッド Compositions and methods using Eutomer
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
US20030232890A1 (en) 2000-11-01 2003-12-18 Sention, Inc. Methods for treating an impairment in memory consolidation
US7619005B2 (en) 2000-11-01 2009-11-17 Cognition Pharmaceuticals Llc Methods for treating cognitive impairment in humans with Multiple Sclerosis
TWI291871B (en) * 2000-11-01 2008-01-01 Cognition Pharmaceuticals Llc Pharmaceutical compositions and use of amphetamine compounds for improving memory and learning
US20120028906A1 (en) * 2009-03-13 2012-02-02 Loma Linda University Method for affecting the timing of cervical ripening and for parturition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0043807A2 (en) * 1980-07-09 1982-01-13 Aktiebolaget Draco 1-(Dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
EP0455155A1 (en) * 1990-05-04 1991-11-06 Boehringer Ingelheim Vetmedica Gmbh Separation of cimaterol enantiomers
WO1992016173A1 (en) * 1991-03-19 1992-10-01 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure terbutaline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66203B1 (en) * 1989-12-04 1995-12-13 Searle & Co System for transdermal albuterol administration
US5362755A (en) * 1990-01-05 1994-11-08 Sepracor, Inc. Method for treating asthma using optically pure (R)-albuterol
US5370135A (en) * 1993-10-13 1994-12-06 Biex, Inc. Use of estriol measurement to monitor tocolytic therapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0043807A2 (en) * 1980-07-09 1982-01-13 Aktiebolaget Draco 1-(Dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
EP0455155A1 (en) * 1990-05-04 1991-11-06 Boehringer Ingelheim Vetmedica Gmbh Separation of cimaterol enantiomers
WO1992016173A1 (en) * 1991-03-19 1992-10-01 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure terbutaline

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BORGSTRÖM L. ET AL: "Relative absorption of the two enantiomers of terbutaline after duodenal administration", EUR. J. CLIN. PHARMACOL., vol. 38, no. 6, 1990, pages 621 - 624, XP002097503 *
See also references of WO9726871A1 *

Also Published As

Publication number Publication date
WO1997026871A1 (en) 1997-07-31
EP0892639A1 (en) 1999-01-27
AU2247997A (en) 1997-08-20
CA2247953A1 (en) 1997-07-31

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Legal Events

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