EP0731710A4 - Verfahren und zusammensetzung fuer die bvehandlung von patienten mit dekompensierter lebererkrankung - Google Patents

Verfahren und zusammensetzung fuer die bvehandlung von patienten mit dekompensierter lebererkrankung

Info

Publication number: EP0731710A4
Authority: EP; European Patent Office
Prior art keywords: patients; treatment; composition; liver disease; decompensated liver
Prior art date: 1993-11-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP94901265A

Other languages

English (en)

French (fr)

Other versions

EP0731710B1 (de

EP0731710A1 (de

Inventor

Paul B Chretien

Milton G Mutchnick

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sciclone Pharmaceuticals LLC

Original Assignee

Wayne State University

Alpha 1 Biomedicals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-05

Filing date

1993-11-05

Publication date

1999-12-22

1993-11-05 Application filed by Wayne State University, Alpha 1 Biomedicals Inc filed Critical Wayne State University

1993-11-05 Priority claimed from PCT/US1993/010619 external-priority patent/WO1995012405A1/en

1996-09-18 Publication of EP0731710A1 publication Critical patent/EP0731710A1/de

1999-12-22 Publication of EP0731710A4 publication Critical patent/EP0731710A4/de

2003-05-14 Application granted granted Critical

2003-05-14 Publication of EP0731710B1 publication Critical patent/EP0731710B1/de

2013-11-05 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Endocrinology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicinal Preparation (AREA)

EP94901265A 1993-11-05 1993-11-05 Thymosin-alpha-1 enthaltende zusammensetzungen zur behandlung von hepatitis b bei patienten mit dekompensierter lebererkrankung Expired - Lifetime EP0731710B1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1993/010619 WO1995012405A1 (en)	1993-11-05	1993-11-05	Method and composition for treatment of patients having decompensated liver disease

Publications (3)

Publication Number	Publication Date
EP0731710A1 EP0731710A1 (de)	1996-09-18
EP0731710A4 true EP0731710A4 (de)	1999-12-22
EP0731710B1 EP0731710B1 (de)	2003-05-14

Family

ID=22237139

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94901265A Expired - Lifetime EP0731710B1 (de)	1993-11-05	1993-11-05	Thymosin-alpha-1 enthaltende zusammensetzungen zur behandlung von hepatitis b bei patienten mit dekompensierter lebererkrankung

Country Status (11)

Country	Link
EP (1)	EP0731710B1 (de)
KR (1)	KR100298859B1 (de)
CA (1)	CA2175337C (de)
DE (1)	DE69332982T2 (de)
DK (1)	DK0731710T3 (de)
ES (1)	ES2194860T3 (de)
HK (1)	HK1021685A1 (de)
MX (1)	MXPA94003453A (de)
MY (1)	MY111342A (de)
NO (1)	NO961775L (de)
PT (1)	PT731710E (de)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993005806A1 (en) *	1991-09-13	1993-04-01	Alpha 1 Biomedicals, Inc.	Composition and method of treating hepatitis c
WO1994001125A1 (en) *	1992-07-13	1994-01-20	Sherman Kenneth E	Composition and method of treating hepatitis b
WO1995011688A1 (en) *	1992-02-06	1995-05-04	Sciclone Pharmaceuticals	Method for treating hepatitis b carriers with minimal disease

1993
- 1993-11-05 PT PT94901265T patent/PT731710E/pt unknown
- 1993-11-05 EP EP94901265A patent/EP0731710B1/de not_active Expired - Lifetime
- 1993-11-05 DK DK94901265T patent/DK0731710T3/da active
- 1993-11-05 CA CA002175337A patent/CA2175337C/en not_active Expired - Fee Related
- 1993-11-05 KR KR1019960702942A patent/KR100298859B1/ko not_active IP Right Cessation
- 1993-11-05 ES ES94901265T patent/ES2194860T3/es not_active Expired - Lifetime
- 1993-11-05 DE DE69332982T patent/DE69332982T2/de not_active Expired - Fee Related
- 1993-11-05 MX MXPA94003453A patent/MXPA94003453A/es not_active IP Right Cessation
1994
- 1994-05-09 MY MYPI94001152A patent/MY111342A/en unknown
1996
- 1996-05-02 NO NO961775A patent/NO961775L/no not_active Application Discontinuation
1998
- 1998-12-19 HK HK98114128A patent/HK1021685A1/xx not_active IP Right Cessation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993005806A1 (en) *	1991-09-13	1993-04-01	Alpha 1 Biomedicals, Inc.	Composition and method of treating hepatitis c
WO1995011688A1 (en) *	1992-02-06	1995-05-04	Sciclone Pharmaceuticals	Method for treating hepatitis b carriers with minimal disease
WO1994001125A1 (en) *	1992-07-13	1994-01-20	Sherman Kenneth E	Composition and method of treating hepatitis b

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MUTCHNICK M.G. ET AL.: "Sustained response to thymosin therapy in patients with chronic hepatitis B", HEPATOLOGY, vol. 16, no. 4(2), 1992, pages 66A, XP002116413 *
MUTCHNICK M.G. ET AL.: "Thymosin treatment of chronic hepatitis B: a placebo-controlled pilot trial", HEPATOLOGY, vol. 14, no. 3, 1991, pages 409 - 415, XP002115980 *
See also references of WO9512405A1 *

Also Published As

Publication number	Publication date
DE69332982T2 (de)	2004-09-09
EP0731710B1 (de)	2003-05-14
CA2175337A1 (en)	1995-05-11
NO961775D0 (no)	1996-05-02
MXPA94003453A (es)	2004-08-16
PT731710E (pt)	2003-09-30
DK0731710T3 (da)	2003-06-16
NO961775L (no)	1996-05-02
CA2175337C (en)	2000-06-20
ES2194860T3 (es)	2003-12-01
DE69332982D1 (de)	2003-06-18
KR100298859B1 (ko)	2001-10-22
EP0731710A1 (de)	1996-09-18
HK1021685A1 (en)	2000-06-23
KR960706352A (ko)	1996-12-09
MY111342A (en)	1999-11-30

Legal Events

Date	Code	Title	Description
1996-08-02	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-09-18	17P	Request for examination filed	Effective date: 19960503
1996-09-18	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE DE DK ES FR GB GR IT NL PT SE
1999-11-17	RIC1	Information provided on ipc code assigned before grant	Free format text: 6A 61K 38/22 A
1999-12-22	A4	Supplementary search report drawn up and despatched	Effective date: 19991108
1999-12-22	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): BE DE DK ES FR GB GR IT NL PT SE
2000-08-30	17Q	First examination report despatched	Effective date: 20000717
2002-10-29	GRAH	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOS IGRA
2002-12-04	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 61K 38/22 A, 7A 61P 31/12 B, 7A 61P 43/00 B
2002-12-04	RTI1	Title (correction)	Free format text: THYMOSINE ALPHA 1 CONTAINING COMPOSITIONS FOR THE TREATMENT OF PATIENTS HAVING DECOMPENSATED LIVER DISEASE
2002-12-11	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 61K 38/22 A, 7A 61P 31/12 B, 7A 61P 43/00 B
2002-12-11	RTI1	Title (correction)	Free format text: THYMOSINE ALPHA 1 CONTAINING COMPOSITIONS FOR THE TREATMENT OF PATIENTS HAVING DECOMPENSATED LIVER DISEASE
2003-03-19	GRAH	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOS IGRA
2003-03-28	GRAA	(expected) grant	Free format text: ORIGINAL CODE: 0009210
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2003-06-11	RAP2	Party data changed (patent owner data changed or rights of a patent transferred)	Owner name: THE BOARD OF GOVERNORSOF WAYNE STATE UNIVERSITY Owner name: SCICLONE PHARMACEUTICALS, INC.
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