EP0730466A4 - Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites - Google Patents

Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Info

Publication number: EP0730466A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; inhibiting hepatocyte; hepatocyte invasion; sporozoites
Prior art date: 1993-09-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP94928067A

Other languages

German (de)

French (fr)

Other versions

EP0730466A1 (en

Inventor

Carla Cerami

Ute Frevert

Phetori Sinnis

Victor Nussenzweig

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

New York University NYU

Original Assignee

New York University NYU

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-10

Filing date

1994-09-09

Publication date

1999-04-14

1994-09-09 Application filed by New York University NYU filed Critical New York University NYU

1996-09-11 Publication of EP0730466A1 publication Critical patent/EP0730466A1/en

1999-04-14 Publication of EP0730466A4 publication Critical patent/EP0730466A4/en

Status Withdrawn legal-status Critical Current

Links

210000003494 hepatocyte Anatomy 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
230000009545 invasion Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1
210000003046 sporozoite Anatomy 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Tropical Medicine & Parasitology (AREA)
Peptides Or Proteins (AREA)

EP94928067A 1993-09-10 1994-09-09 Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites Withdrawn EP0730466A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11969493A	1993-09-10	1993-09-10
US119694		1993-09-10
PCT/US1994/010186 WO1995007094A1 (en)	1993-09-10	1994-09-09	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Publications (2)

Publication Number	Publication Date
EP0730466A1 EP0730466A1 (en)	1996-09-11
EP0730466A4 true EP0730466A4 (en)	1999-04-14

Family

ID=22385814

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94928067A Withdrawn EP0730466A4 (en)	1993-09-10	1994-09-09	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Country Status (4)

Country	Link
EP (1)	EP0730466A4 (en)
AU (1)	AU7724894A (en)
CA (1)	CA2171562A1 (en)
WO (1)	WO1995007094A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9266930B1 (en)	1993-03-05	2016-02-23	Epimmune Inc.	Inducing cellular immune responses to Plasmodium falciparum using peptide and nucleic acid compositions
FR2840220A1 (en) *	2002-05-28	2003-12-05	Univ Paris Curie	Inhibiting entry of malarial sporozoites into hepatocytes, useful for prevention of malaria, using an inhibitor of interaction between CD81 and Plasmodium-associated ligand
SG149058A1 (en) *	2003-12-19	2009-01-29	Seattle Biomedical Res Inst	Live genetically attenuated malaria vaccine
US8168166B2 (en)	2003-12-19	2012-05-01	Seattle Biomedical Research Institute	Live genetically attenuated malaria vaccine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0432965A1 (en) *	1989-12-08	1991-06-19	Smithkline Beecham Corporation	Malaria vaccine
EP0517182A1 (en) *	1991-06-03	1992-12-09	Mitsubishi Chemical Corporation	Hepatocyte-growth agent
WO1993002704A1 (en) *	1991-07-31	1993-02-18	Institut Pasteur	Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum
WO1993003057A1 (en) *	1991-07-31	1993-02-18	Institut Pasteur	Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions
EP0578342A2 (en) *	1992-05-14	1994-01-12	W.R. Grace & Co.-Conn.	Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor
WO1994006464A1 (en) *	1992-09-17	1994-03-31	New York University	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

1994
- 1994-09-09 EP EP94928067A patent/EP0730466A4/en not_active Withdrawn
- 1994-09-09 AU AU77248/94A patent/AU7724894A/en not_active Abandoned
- 1994-09-09 CA CA002171562A patent/CA2171562A1/en not_active Abandoned
- 1994-09-09 WO PCT/US1994/010186 patent/WO1995007094A1/en not_active Application Discontinuation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0432965A1 (en) *	1989-12-08	1991-06-19	Smithkline Beecham Corporation	Malaria vaccine
EP0517182A1 (en) *	1991-06-03	1992-12-09	Mitsubishi Chemical Corporation	Hepatocyte-growth agent
WO1993002704A1 (en) *	1991-07-31	1993-02-18	Institut Pasteur	Mixture of peptide constituents having vaccinating properties against paludism particularly due to plasmodium falciparum
WO1993003057A1 (en) *	1991-07-31	1993-02-18	Institut Pasteur	Polypeptides capable of in vivo induction of antibodies themselves capable of inhibiting the invasion of red blood corpuscles by merozoites of p.falciparum, related products and their use in producing vaccine compositions
EP0578342A2 (en) *	1992-05-14	1994-01-12	W.R. Grace & Co.-Conn.	Purification and characterization of a CSVTCG-specific tumor cell adhesion receptor
WO1994006464A1 (en) *	1992-09-17	1994-03-31	New York University	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CERAMI, CARLA ET AL: "The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites", CELL (CAMBRIDGE, MASS.) (1992), 70(6), 1021-33 CODEN: CELLB5;ISSN: 0092-8674, 1992, XP002090186 *
See also references of WO9507094A1 *
SINNIS, PHOTINI ET AL: "Structural and functional properties of region II-plus of the malaria circumsporozoite protein", J. EXP. MED. (1994), 180(1), 297-306 CODEN: JEMEAV;ISSN: 0022-1007, 1994, XP002090187 *

Also Published As

Publication number	Publication date
WO1995007094A1 (en)	1995-03-16
EP0730466A1 (en)	1996-09-11
AU7724894A (en)	1995-03-27
CA2171562A1 (en)	1995-03-16

Legal Events

Date	Code	Title	Description
1996-07-26	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-09-11	17P	Request for examination filed	Effective date: 19960410
1996-09-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE CH DE DK ES FR GB IT LI NL SE
1999-04-14	A4	Supplementary search report drawn up and despatched	Effective date: 19990225
1999-04-14	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): BE CH DE DK ES FR GB IT LI NL SE
2000-09-08	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2000-10-25	18D	Application deemed to be withdrawn	Effective date: 20000331

Publication	Publication Date	Title
EP0716603A4 (en)	2000-10-04	Methods and compositions for inhibiting uridine secretion
GB2294465A8 (en)	1996-05-28	Perfluoroelastomeric compositions and methods
HU9503088D0 (en)	1995-12-28	Erythropoietin analog compositions and methods
GB9410246D0 (en)	1994-07-13	Processing stabiliser composition
ZA942052B (en)	1995-09-26	Tricritical point composition
KR950013580B1 (en)	1995-11-09	Method and compositions for difusion patierning
EP0734398A4 (en)	1997-04-16	Compounds and methods
AU5130793A (en)	1994-04-12	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites
IL109036A0 (en)	1994-06-24	Method and compositions for disrupting the epithelial barrier function
GB9307449D0 (en)	1993-06-02	Surfactant composition
EP0730466A4 (en)	1999-04-14	Compositions and methods for inhibiting hepatocyte invasion by malarial sporozoites
ZA919577B (en)	1993-09-06	Composition and method for preventing fluorosis
GB2274656B (en)	1996-12-11	Alloying additive
GB9224295D0 (en)	1993-01-06	Method and composition
GB2274650B (en)	1996-06-26	Composition for skin barrier
AU1378495A (en)	1995-07-17	Methods and compositions for inhibiting thrombogenesis
ZA946967B (en)	1995-05-08	Lyophillisate composition
GB9417430D0 (en)	1994-10-19	Composition
GB9320370D0 (en)	1993-11-24	Frit-containing composition
GB9204445D0 (en)	1992-04-15	Switching arrangement and method
GB9308051D0 (en)	1993-06-02	Method and composition
GB9117725D0 (en)	1991-10-02	Skin-care composition and method
GB9321025D0 (en)	1993-12-01	Antimalarial compositions and method
GB9313100D0 (en)	1993-08-11	Lockable casement stay
GB9111824D0 (en)	1991-07-24	Method and composition