EP0722326A4 - Highly sulfated maltooligosaccharides with heparin-like properties - Google Patents

Highly sulfated maltooligosaccharides with heparin-like properties

Info

Publication number
EP0722326A4
EP0722326A4 EP94931314A EP94931314A EP0722326A4 EP 0722326 A4 EP0722326 A4 EP 0722326A4 EP 94931314 A EP94931314 A EP 94931314A EP 94931314 A EP94931314 A EP 94931314A EP 0722326 A4 EP0722326 A4 EP 0722326A4
Authority
EP
European Patent Office
Prior art keywords
heparin
properties
highly sulfated
maltooligosaccharides
sulfated maltooligosaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94931314A
Other languages
German (de)
French (fr)
Other versions
EP0722326A1 (en
Inventor
Peter Fugedi
David John Tyrrell
Robert James Tressler
Robert Joseph Stack
Masayuki Ishihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycomed Inc
Original Assignee
Glycomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomed Inc filed Critical Glycomed Inc
Publication of EP0722326A1 publication Critical patent/EP0722326A1/en
Publication of EP0722326A4 publication Critical patent/EP0722326A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP94931314A 1993-10-07 1994-10-04 Highly sulfated maltooligosaccharides with heparin-like properties Withdrawn EP0722326A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13348393A 1993-10-07 1993-10-07
US133483 1993-10-07
PCT/US1994/011368 WO1995009637A1 (en) 1993-10-07 1994-10-04 Highly sulfated maltooligosaccharides with heparin-like properties

Publications (2)

Publication Number Publication Date
EP0722326A1 EP0722326A1 (en) 1996-07-24
EP0722326A4 true EP0722326A4 (en) 1999-10-06

Family

ID=22458825

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94931314A Withdrawn EP0722326A4 (en) 1993-10-07 1994-10-04 Highly sulfated maltooligosaccharides with heparin-like properties

Country Status (5)

Country Link
EP (1) EP0722326A4 (en)
JP (1) JPH09503510A (en)
AU (1) AU700451B2 (en)
CA (1) CA2171465A1 (en)
WO (1) WO1995009637A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
AUPO888497A0 (en) * 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
DE19747195A1 (en) * 1997-10-24 1999-04-29 Knoll Ag Compositions for treating diabetic retinopathy
AU3837300A (en) * 1999-04-15 2000-11-02 Takara Shuzo Co., Ltd. Remedies
US6608042B2 (en) * 2000-03-28 2003-08-19 Aventis Pharma, S.A. Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof
SK288335B6 (en) 2001-09-12 2016-02-02 Sigma-Tau Research Switzerland S.A. Partially or totally N-desulphated, N-reacetylated heparin, method for its preparation, its use for preparation of medicament having heparanaze inhibiting activity, antiangiogenic and anti-inflammatory activity and pharmaceutical composition containing its
JP5139797B2 (en) * 2004-03-04 2013-02-06 プロジェン ファーマシューティカルズ リミテッド Sulfated oligosaccharide derivatives
CN100363373C (en) * 2005-01-14 2008-01-23 庄茅 Preparation method of isomalto loigosaccharide sulphate (IMOS)
MX338213B (en) * 2007-10-16 2016-04-07 Progen Pharmaceuticals Ltd Novel sulfated oligosaccharide derivatives.
CA2861077A1 (en) * 2012-01-30 2013-08-08 Baxter International Inc. Non-anticoagulant sulfated or sulfonated polysaccharides
EP2832848B1 (en) 2012-03-30 2019-02-13 Ajinomoto Co., Inc. Culture medium for proliferating stem cell, which contains sulfated compound
RU2019121873A (en) 2016-12-13 2021-01-15 БЕТА ТЕРАПЬЮТИКС ПиТиУай ЛТД HEPARANASE INHIBITORS AND THEIR APPLICATION
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (en) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc Oligosaccharide derivative
EP0479093A1 (en) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Oligosaccharide derivatives and their use as medicaments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066829A (en) * 1976-07-12 1978-01-03 American Cyanamid Company Malto-dextrin poly(H-)sulfates
US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
JPS5951583A (en) * 1983-06-15 1984-03-26 Nippon Telegr & Teleph Corp <Ntt> Semiconductor laser device
US4470976A (en) * 1983-08-29 1984-09-11 American Cyanamid Company Poly-cation salt of 4-O-polyhexaose-thio-arylene sulfates
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmaceutical or veterinary compositions containing modified heparin having reduced anticoagulant activity
WO1989003684A1 (en) * 1987-10-30 1989-05-05 Chugai Seiyaku Kabushiki Kaisha Anti-hiv agent
JPH036457A (en) * 1989-06-02 1991-01-11 Koyo Seiko Co Ltd Bearing apparatus for axle equipped with wheel rotational speed detector
JP2792914B2 (en) * 1989-06-02 1998-09-03 光洋精工株式会社 Axle bearing device with wheel rotational speed detector

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108713A (en) * 1980-02-01 1981-08-28 Nippon Kayaku Co Ltd Antitumor preparation
JPH03145496A (en) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc Oligosaccharide derivative
EP0479093A1 (en) * 1990-10-03 1992-04-08 F. Hoffmann-La Roche Ag Oligosaccharide derivatives and their use as medicaments

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 15, no. 361 (C - 867) 12 September 1991 (1991-09-12) *
PATENT ABSTRACTS OF JAPAN vol. 5, no. 184 (C - 80) 21 November 1981 (1981-11-21) *
See also references of WO9509637A1 *

Also Published As

Publication number Publication date
AU8013694A (en) 1995-05-01
CA2171465A1 (en) 1995-04-13
JPH09503510A (en) 1997-04-08
EP0722326A1 (en) 1996-07-24
AU700451B2 (en) 1999-01-07
WO1995009637A1 (en) 1995-04-13

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