EP0717622A4 - Methods of treating hiv with azaspiranes - Google Patents

Methods of treating hiv with azaspiranes

Info

Publication number: EP0717622A4
Authority: EP; European Patent Office
Prior art keywords: azaspiranes; methods; treating hiv; hiv; treating
Prior art date: 1993-07-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP94925100A

Other languages

German (de)

French (fr)

Other versions

EP0717622A1 (en

Inventor

Alison Mary Badger

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-23

Filing date

1994-07-22

Publication date

1998-09-09

1994-07-22 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1996-06-26 Publication of EP0717622A1 publication Critical patent/EP0717622A1/en

1998-09-09 Publication of EP0717622A4 publication Critical patent/EP0717622A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP94925100A 1993-07-23 1994-07-22 Methods of treating hiv with azaspiranes Withdrawn EP0717622A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB939315351A GB9315351D0 (en)	1993-07-23	1993-07-23	Methods
GB9315351		1993-07-23
PCT/US1994/008274 WO1995003049A1 (en)	1993-07-23	1994-07-22	Methods of treating hiv with azaspiranes

Publications (2)

Publication Number	Publication Date
EP0717622A1 EP0717622A1 (en)	1996-06-26
EP0717622A4 true EP0717622A4 (en)	1998-09-09

Family

ID=10739366

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94925100A Withdrawn EP0717622A4 (en)	1993-07-23	1994-07-22	Methods of treating hiv with azaspiranes

Country Status (9)

Country	Link
EP (1)	EP0717622A4 (en)
JP (1)	JPH09500646A (en)
CN (1)	CN1130873A (en)
AU (1)	AU7514094A (en)
CA (1)	CA2167843A1 (en)
GB (1)	GB9315351D0 (en)
NZ (1)	NZ271496A (en)
WO (1)	WO1995003049A1 (en)
ZA (1)	ZA945417B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9315340D0 (en) *	1993-07-23	1993-09-08	Smithkline Beecham Corp	Methods
GB9315306D0 (en) *	1993-07-23	1993-09-08	Smithkline Beecham Corp	Methods
BR9601909A (en) *	1995-07-13	1999-10-13	Smithkline Beecham Corp	N, n-diethyl-8,8-dipropyl-2-azaspiro (4,5) decane-2-propan amine dimaleate
BR9709007A (en) *	1996-05-17	2000-01-04	Anormed Inc	Use of substituted azaspirane in the treatment of asthma.

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992014462A1 (en) *	1991-02-19	1992-09-03	Smithkline Beecham Corporation	Cytokine inhibitors
WO1993014760A2 (en) *	1992-01-28	1993-08-05	Smithkline Beecham Corporation	Methods
WO1993015735A1 (en) *	1992-01-28	1993-08-19	Smithkline Beecham Corporation	(non descriptive)-a method for delaying hiv individual aids by administration of substituted azaspirane compounds
WO1995003047A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Human immunodeficiency virus treatments
WO1995003042A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Method of inhibiting the replication of human immunodeficiency viruses with substituted azaspiranes
WO1995003041A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4963557A (en) *	1987-09-28	1990-10-16	Smithkline Beecham Corporation	Immunomodulatory azaspiranes

1993
- 1993-07-23 GB GB939315351A patent/GB9315351D0/en active Pending
1994
- 1994-07-22 ZA ZA945417A patent/ZA945417B/en unknown
- 1994-07-22 JP JP7505330A patent/JPH09500646A/en not_active Ceased
- 1994-07-22 WO PCT/US1994/008274 patent/WO1995003049A1/en not_active Application Discontinuation
- 1994-07-22 NZ NZ271496A patent/NZ271496A/en unknown
- 1994-07-22 AU AU75140/94A patent/AU7514094A/en not_active Abandoned
- 1994-07-22 CN CN94193382A patent/CN1130873A/en active Pending
- 1994-07-22 CA CA002167843A patent/CA2167843A1/en not_active Abandoned
- 1994-07-22 EP EP94925100A patent/EP0717622A4/en not_active Withdrawn

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992014462A1 (en) *	1991-02-19	1992-09-03	Smithkline Beecham Corporation	Cytokine inhibitors
WO1993014760A2 (en) *	1992-01-28	1993-08-05	Smithkline Beecham Corporation	Methods
WO1993015735A1 (en) *	1992-01-28	1993-08-19	Smithkline Beecham Corporation	(non descriptive)-a method for delaying hiv individual aids by administration of substituted azaspirane compounds
WO1995003047A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Human immunodeficiency virus treatments
WO1995003042A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Method of inhibiting the replication of human immunodeficiency viruses with substituted azaspiranes
WO1995003041A1 (en) *	1993-07-23	1995-02-02	Smithkline Beecham Corporation	Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BADGER A M ET AL: "ANTIARTHRITIC AND SUPPRESSOR CELL INDUCING ACTIVITY OF AZASPIRANES:STRUCTURE-FUNCTION RELATIONSHIPS OF A NOVEL CLASS OF IMMUNOMODULATORY AGENTS", JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 11, November 1990 (1990-11-01), pages 2963 - 2970, XP000605424 *
P.S. SARIN ET AL.: "INHIBITION OF HTLV-III REPLICTION IN CELL CULTURES", NATO ASI SER., SER. A, vol. 120, 1986, pages 329 - 342, XP002069579 *
S. GOODMAN: "THERAPEUTIC EFFECTS OF ORGANIC GERMANIUM", MEDICAL HYPOTHESES, vol. 26, 1988, pages 207 - 215, XP002069578 *
See also references of WO9503049A1 *

Also Published As

Publication number	Publication date
AU7514094A (en)	1995-02-20
CA2167843A1 (en)	1995-02-02
EP0717622A1 (en)	1996-06-26
NZ271496A (en)	1999-06-29
ZA945417B (en)	1995-05-10
WO1995003049A1 (en)	1995-02-02
CN1130873A (en)	1996-09-11
JPH09500646A (en)	1997-01-21
GB9315351D0 (en)	1993-09-08

Legal Events

Date	Code	Title	Description
1996-05-10	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-06-26	17P	Request for examination filed	Effective date: 19960201
1996-06-26	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1996-06-26	AX	Request for extension of the european patent	Free format text: SI PAYMENT 960201
1996-06-26	RAX	Requested extension states of the european patent have changed	Free format text: SI PAYMENT 960201
1998-08-19	RHK1	Main classification (correction)	Ipc: A61K 31/40
1998-09-09	A4	Supplementary search report drawn up and despatched	Effective date: 19980722
1998-09-09	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-04-01	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1999-05-19	18D	Application deemed to be withdrawn	Effective date: 19981009
2006-03-03	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1012279 Country of ref document: HK

Publication	Publication Date	Title
GB9309397D0 (en)	1993-06-23	Laser treatment
EP0814814A4 (en)	1999-01-13	Methods for the treatment of thrombosis
EP0734398A4 (en)	1997-04-16	Compounds and methods
GB2276178B (en)	1997-01-15	Treatment of textiles
GB9305759D0 (en)	1993-05-05	Hiv therapy method and agents
GB9203039D0 (en)	1992-03-25	Treatment
PL313740A1 (en)	1996-07-22	Method of
GB9201920D0 (en)	1992-03-18	Novel treatment i
EP0717622A4 (en)	1998-09-09	Methods of treating hiv with azaspiranes
GB9308802D0 (en)	1993-06-09	Treatment
GB2221171B (en)	1992-09-23	Treating surfaces
EP0752856A4 (en)	1997-09-10	Methods of treating hyperlipidemia
GB9321971D0 (en)	1993-12-15	Method of treatment
GB9321796D0 (en)	1993-12-15	Method of treatment
GB9307004D0 (en)	1993-05-26	Method of treatment
GB9301422D0 (en)	1993-03-17	Process and compounds
GB9321592D0 (en)	1993-12-08	Novel compounds and treatment
GB9321591D0 (en)	1993-12-08	Novel compounds and treatment
GB9302314D0 (en)	1993-03-24	Novel compounds and treatment
GB9302289D0 (en)	1993-03-24	Novel compounds and treatment
CA72766S (en)	1993-07-02	Set of handles
GB9310836D0 (en)	1993-07-14	Treatment
PL55382Y1 (en)	1997-08-29	Set of symmetrisers
GB9308853D0 (en)	1993-06-16	Novel method of treatment
GB9326020D0 (en)	1994-02-23	Novel method of treatment