EP0710071A1 - High concentrated, solid mepiquat chloride and chlormequat chloride products - Google Patents
High concentrated, solid mepiquat chloride and chlormequat chloride productsInfo
- Publication number
- EP0710071A1 EP0710071A1 EP94923717A EP94923717A EP0710071A1 EP 0710071 A1 EP0710071 A1 EP 0710071A1 EP 94923717 A EP94923717 A EP 94923717A EP 94923717 A EP94923717 A EP 94923717A EP 0710071 A1 EP0710071 A1 EP 0710071A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- plant growth
- growth regulator
- dryer
- dry
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
Definitions
- the present invention relates to methods for making flowable, highly concentrated powders and tablets of hygroscopic plant growth regulator compounds, and more specifically to processes to 10 dry mepiquat chloride and chlormequat chloride aqueous solutions to form flowable highly concentrated solid products.
- Plant growth regulators affect the physiology of plant growth and influence the natural rhythm of a plant. More specifically, plant
- 15 growth regulators may, for example, reduce plant height, stimu ⁇ late seed germination, induce flowering, promote or inhibit fog, darken leaf coloring, minimize lodging of cereals, slow grass growth on lawns, reduce boll rot and provide better boll reten ⁇ tion in cotton.
- Plant growth regulators may be applied to plants in a variety of methods including different formulations. Of these various methods, use of liquid and dry compositions are the most common. The particular formulation desired and resulting efficacy enhan-
- 25 cement will greatly depend upon the species to be treated, envi ⁇ ronmental conditions, the geographical area and the climatology of the area at the time of treatment.
- the plant growth regulator known trivially as mepiquat chloride, 30 is generally used to control various aspects of cotton boll growth. See, for example, Khafaga, Angew. Botanik 57, 257-265 (1983); Sawan et al., J. Agronomy & Plant Science, 154, 120-128 (1985); U.S. Patents 3,905,798 and 4,447,255; and "The Pesticide Manual", 9th Edition, The British Crop Protection Council, 35 Farnham, Surrey, Great Britain, Entry No. 7920.
- the plant growth regulator known trivially as chlormequat chlo ⁇ ride, is generally used to reduce lodging of cereals (cf. "The Pesticide Manual”, 9th Edition, The British Crop Protection Coun- 40 cil, Farnham, Surrey, Great Britain, Entry No. 2420) .
- Mepiquat chloride and chlormequat chloride are used as plant growth regulators in agriculture.
- Mepiquat chloride and chlorme ⁇ quat chloride have high water solubilities of more than 1 kg/L at 45 20°C.
- the melting point of mepiquat chloride is 223°C
- chlorme- quate chloride begins to decompose at 210°C. Both substances are very hygroscopic, readily absorbing moisture from humid air, so much so, that the dry powders can turn to li ⁇ quid when exposed to ambient humid air.
- the solid mepiquat chloride or chlormequat chloride is strongly caking and sticking to container surfaces, even at low residual water con ⁇ tents of less than 0.5 wt.-%.
- Solid forms of plant growth regulators offer a number of key ad- vantages, including convenience, increased stability and shelf life, as well as reduced packaging, storage and shipping costs.
- free-flowing, non-caking solid mepiquat chloride and chlormequat chloride formulations can be achieved by mixing the solid hygroscopic plant growth regulator with finely divided, highly absorptive inerzs. In such mixtures, concentrations of the plant growth regulator of up to about 99 wt.-% are achievable. When the mixtures of the invention are directly applied in a spray tank, the plant growth regulator dissolves instantly in the water without residues.
- the preferred plant growth regulators of the present invention include the group consisting of 1, l-dimethyl-3, 4-dehydro- piperidinium bromide, 4-chloro-l,1-dimethyl piperidinium bromide, 1, I-dimethylhexahydropyridazinium bromide, and 1, 1-dimethyl- piperidinium chloride, also known as mepiquat chloride and 2-chloroethyltrimethylammonium chloride, also known as chlorme ⁇ quat chloride.
- Figure 1 illustrates a spray dryer used in a method of the pre ⁇ sent invention.
- Figure 2 illustrates a double drum dryer used in a method of the present invention.
- Figure 3 illustrates a batch vacuum dryer used in a method of the present invention.
- the term "agriculturally acceptable” includes agricultural, industrial and residential use.
- plant growth regulator(s) (hereinafter abbre ⁇ viated as "PGR") or “regulation” includes the following plant responses: inhibition of cell elongation, for example reduction in stem height and internodal distance, strengthening of the stem wall, thus increasing the resistance to lodging; compact growth in ornamentals for the economic production of improved quality plants; promotion of better fruiting; increasing the number of ovaries with a view to stepping up yield; promotion of senescence of the formation of tissue enabling fruit to absciss; defoliation of nursery and ornamental bushes and trees for mail-order busi- ness in the fall; defoliation of trees to interrupt parasitic chains of infection; hastening of ripening, with a view to pro- gramming the harvest by reducing the harvest to one to two pik- kings and interrupting the food-chain for injurious insects.
- PGR plant growth regulator
- PGR formulations of the present invention may be used to form both package and tank mix compositions.
- the present preferred invention comprises PGR compositions com ⁇ prising an agriculturally and plant growth regulating effective amount of a hygroscopic PGR, and more preferably, an N,N-dime- thylpiperidinium or N,N-dimethylammonium salt in a dry flowable highly concentrated powder.
- Preferred PGRs include salts of the formula:
- R is methyl or ethyl
- X is the anion of an inorganic or organic, but not phytotoxic acid, preferably bromide or chloride
- the groups A independently denote methyl, ethyl or propyl which independently may be substituted by chloro or bromo, or the groups A together denote a chain of 4 or 5 methylene groups, which chain may be substituted by chloro, bromo, methyl, chloro- methyl, bromomethyl, hydroxymethyl, and methylene, or which chain containing one or two double bonds, or A is the chain -(CH 2 ) n -NH-, where n is 3 or 4, disclosed in U.S. Patent 3,905,798 and hereby incorporated by reference.
- PGRs include 1, l-dimethyl-3, -de- hydro-piperidinium bromide, 4-chloro-l,l-dimethyl-piperidinium bromide, 1,1-dimethylhexahydropyridazinium bromide, 1,1-dimethyl- piperidinium chloride and 2-chloroethyltrimethylammonium chlo ⁇ ride.
- the most preferred plant growth regulators are 1,1-dimethyl-pipe- ridinium chloride, also known as N,N-dimethylpi ⁇ eridinium chlo- ride or mepiquat chloride, which is commercially available under the registered trademark Pix® (BASF AG, Germany) and 2-chloroe- thyltrimethylammonium chloride or chlormequat chloride, which is commercially available under the registered trademark Cycocel® (BASF AG, Germany) .
- mepiquat chloride will be used. However, the methods described apply equally to other hygroscopic PGRs, especially to chlormequat chloride.
- silica is injected in the inlet air stream of a spray dryer at a controlled rate.
- a spray dryer of the type illustrated in Figure 1 may be used.
- the aqueous PGR feed solution is agi- tated in a feed tank (2) and fed through a line (4) via a feed pump (6) into the spray dryer unit (8) .
- the aqueous PGR feed so ⁇ lution is introduced into the spray dryer unit by an atomizing means (10) .
- An inlet air heating means (12) provides heat to the dryer at a temperature of about 150 to about 250°C.
- a flow aid such as silica is stored in a feed hopper (14) and in ⁇ jected into the spray dryer unit (8) via a screw feeder (16) through a line by an air eductor (18) .
- the silica adheres to the forming droplets or partially dried particles formed by the aqueous mepiquat chloride feed solution in the vicinity of the atomizer (10) and reduces or eliminates the tendency of the partially dried mepiquat chloride particles to stick to the spray drying unit walls (20, 22), the ducts (24), and the cyclone (26) .
- the silica also renders the powder more flowable, eliminating caking in the drum even when stored for long periods of time provided the drum excludes ambient moist air.
- the flowing powder is then suitable for commercial tablet- ting or for filling water soluble bags, e.g. made of polyvinyl alcohol (PVA) films and marketed under trademarks as Monosol M7030® or Monosol M8532®.
- PVA polyvinyl alcohol
- the rate at which the aqueous PGR feed solution is fed into the spray dryer unit is not critical and is dependent upon the size of the spray dryer used. This rate is easily determined by those skilled in the art.
- a preferred method dries the mepiquat chloride solution with a double drum dryer as illustrated in Figure 2.
- the double drum dryer has a pair of hollow, rotating drums (28, 30) whose surfaces are scraped by a knife (32) .
- High pressure steam is in ⁇ troduced to the interior of the drums and mepiquat chloride solu ⁇ tion added continuously via a feed line (34) to the nip between the drums (36) .
- the drums turn toward one another, by means of a conveyor, for example 38 depositing a portion of the liquid, boi ⁇ ling mepiquat chloride solution on the drum surface (28, 30) where boiling is initiated.
- the thin film of mepiquat chloride's water boils off into the vapor hood (40) and a solid film remains that is scraped by sharp knife (32) from the turning drum surface (28,30).
- the material is then collected and the flow aid is added to it to improve flowability and impart anti-caking properties prior to tabletting or filling water solu ⁇ ble bags.
- the plant growth regulator feed solution is preferably charged into the double drum dryer at a rate of about 5 gm/min. to about 200 gm/min. per square foot (about 9.3 dm 2 ) of heated surface and the aqueous plant growth regulator is preferably charged into the double drum dryer into the nip between the drums.
- a preferred embodiment of the drying process utilizes a batch va- cuum dryer with chopping blades which can also be described as a mechanical fluid bed.
- the most preferred batch vacuum dryer is a Littleford® type (or Lodige) vacuum dryer, as illustrated in Fi ⁇ gure 3.
- the vacuum dryer unit (52) consists of double jacket (42, 44) . Inside the double jacket is a hollow ro ⁇ tating shaft (46) with attached plough shaped mixing elements (48) .
- Aqueous PGR feed solution is fed via a line (50) into the vacuum dryer unit (52) .
- Steam or hot water (54) is fed via a line (56) into a jacket (42) which surrounds the vacuum dryer unit (52), and optionally through the hollow rotating shaft (46) .
- Agitating means (57) in the interior of the vacuum dryer unit (52) agitates the aqueous PGR feed solution.
- a vacuum means (58), which may be a pump or vacuum jet unit is introduced into and applied to the vacuum dryer unit (52) .
- the vacuum and applied jacket heat causes the evaporation of the water from the aqueous PGR feed solution.
- the evaporated water boils up, passes through a bag collector means (60), and is recovered by a condenser (62) and collected in a condensate tank (64) .
- Mixing elements (48) are used to divide the pa- ste, breaking it up, and bringing the interior moisture to the surface so as to expose it to the vacuum to increase the drying rate. As the material solidifies, the chopping means breaks the material into small particles to maintain the high drying rate.
- a free-flowing, non-caking solid mepiquat chloride formulation can be achieved by mixing the solid mepiquat chloride with a fi ⁇ nely divided, highly absorptive inert flow aid such as silica.
- a fi ⁇ nely divided, highly absorptive inert flow aid such as silica.
- the addition of silica or other flow aid renders the powder flo ⁇ wable and non-caking, and suitable for tabletting or filling water soluble bags.
- the flow aid is introduced manually or mecha ⁇ nically through a port on or near the top of the drying chamber.
- silica or other flow aid to im ⁇ prove flowability and prevent caking.
- inert additives inc ⁇ lude any form of silica including fumed silicas, precipitated si ⁇ licas, aluminum silicates, magnesium silicates, and the like, zeolites, bentoinites, montmorillonites, and attapulgites and mixtures thereof.
- the most preferred silica is commercially avai ⁇ lable as Sipernat® 50S, which is a synthetic amorphous silicon dioxide hydrate.
- the weight of silica per weight of mepiquat chloride in all of these drying processes is about 0.2:100 to 3:100, and more parti ⁇ cularly, about 2:100.
- binders, fillers, and/or disintegrants can be dissolved in the feed solu ⁇ tion before drying.
- Suitable binders, fillers, and/or disintegrants include water-so- luble cellulose derivatives, cellulose derivatives, carboxymethyl cellulose, hydroxypropyl methylcellulose, water soluble gums such as gum arabic, gum tragacanth, alginates, gelatin, and polyvinyl- pyrollidone, cross-linked polyvinylpyrrolidone, microcrystalline cellulose, modified starches such as sodium carboxymethyl starch, and mixtures thereof.
- Preferred binders, fillers, and/or disintegrants are carboxy ⁇ methyl cellulose.
- suitable fillers, binders, and/or disintegrants include any water soluble starch, corn syrup, dextrin or pregelatinized starch which is at least partially soluble in water at ambient temperature.
- pregelatinized starch marketed by the National Starch and Chemical Corporation under the trade name Instant Celar Gel®.
- pregelatinized corn starch marketed by the Hubinger Company under the trade name OK Pre-Gel® can be used.
- binders suitable for use are pre ⁇ gelatinized food starch, refined from tapioca and marketed under the trade name Instant Gel®; stable, modified amylopectin marke ⁇ ted under the trade name Kosol®; a low viscosity tapioca dextrin marketed under the trade name Crystal Gum®; dextrinized corn starch marketed under the trade name Purity Glaze®; maltodextrin marketed under the trade name Maltrin®, such as MO40 by Grain Processing corporation.
- the preferred amount of binders, fillers, and/or disintegrants in the feed solution is from about 0.1 to about 99.7 wt.-%.
- the above-described powders, with and without fillers, binders, and/or disintegrating agents can then be tabletted or filled into water soluble bags.
- the high potency powders which contain only the ' hygroscopic PGR active material and silica flow aid, tablet without aid of binders, fillers, and/ or disintegrants, or lubricants on a commercial tablet press.
- the tablets formed are of commercial quality, having reproducible weight, sufficient tablet strength, and acceptable solubility.
- Water absorbance is minimal provided that the tablets are made in a dehumidified room.
- the tablets can be dissolved and passed through a 50 mesh screen such as that found on spray equipment without residue.
- the formulations of the present invention contain from about 0.1 to about 99.8 wt.-%, and preferably from about 95 to about 99 wt.-% of active ingredient.
- the concentration of regulator active ingredient will be at least 6 ml/acre (about 0.0125 pints/acre) .
- concentrations of mepiquat chloride up to about 99 wt.-% are achievable.
- the mepiquat chloride dissolves instantly in the water and this spray solution passes a 50 mesh screen of the spray equipment without residues.
- the tablets can be manufactured by compressing the mixtures on tablet machines.
- other inert ingredients like disintegrants, binders, fillers, and/or disintegrants, wet- ting agents or lubricants can be blended with the PGR mixture.
- wetting agents and lubricants can be incorpora ⁇ ted by addition in the drying step—either into the PGR liquid solution before drying, or can be added with the inert flow aid during drying.
- compositions of the present invention may also include other ingredients or adjuvants commonly employed in the art.
- ingredients include drift control agents, defoa- ming agents, preservatives, surfactants, fertilizers, phytotoxi- cants, herbicides, pesticides, insecticides, fungicides, wetting agents, adherents, nematocides, bactericides, trace elements, synergists, antidotes, mixtures thereof and other such adjuvants well known in the plant growth regulator art.
- compositions of the pre ⁇ sent invention along with sequential treatments with these other components for optimal effect.
- compositions of the present invention may be applied to plants.
- the application of liquid and particulate solid plant growth regulator compositions to above ground portions of plants may be carried out by conventional methods, for example, boom and hand application, including sprayers or dusters.
- the composition may be applied aerially as a spray, if desired.
- the mixtures of the present invention are preferably used in the form of aqueous solutions.
- the mixtures are applied in a conventional manner, for example, by spraying, atomizing, watering or disinfecting seed.
- compositions are being used. In any event, they should ensure a fine distribution of the active ingredients in the composition.
- the above plant growth regulator formulation may then be disper ⁇ sed in water and sprayed onto plants according to the method of the present invention.
- Powders, dusts and broadcasting agents may be prepared by mixing or grinding the active ingredients with a solid carrier.
- Granules for example, coated, impregnated or homogeneous granu ⁇ les, may be prepared by bonding the active ingredients to solid carriers.
- solid carriers are mineral earths such as silicic acid, silica gels, silicates, talc, kaolin, Attaclay, li ⁇ mestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, and ureas, and vegetable products such as grain flours, bark meal, wood meal, and nutshell meal, cellulosic powders, and the like.
- compositions of the present invention are opti- mal even at low application rates.
- the compositions of this invention may be prepared, for example, by adding, in any order, the various com- ponents of the composition of the present invention.
- mepiquat chloride which is an aqueous concentrate containing 42 gms/1 (about 0.35 pounds per gallon (US)) of mepiquat chloride (4.2 wt.-%).
- US pounds per gallon
- Example 1 One hundred grams of the mixture described in Example 1 were pak- kaged using a bag made of a water soluble polyvinyl alcohol film (Monosol® M7030, from Chris-Craft Industries, USA) . This water soluble bag was dropped into a spray tank filled with about 95 liters (25 gallons) tap water at room temperature. The water was circulated through a 50 mesh screen. The mepiquat chloride and the film of the bag dissolved completely within 10 minutes. There was no residue on the 50 mesh screen.
- a water soluble polyvinyl alcohol film Monosol® M7030, from Chris-Craft Industries, USA
- Example 4 One hundred grams of the mixture described in Example 4 were pak- kaged using a bag made of a water soluble polyvinyl alcohol film (Monosol® M8532, from Chris-Craft Industries, USA) . This water soluble bag was dropped into a spray tank filled with about 95 liters (25 gallons) tap water at room temperature. The water was circulated through a 100 mesh screen. The mepiquat chloride and the film dissolved completely within 10 minutes. These was no re ⁇ sidue on the 100 mesh screen.
- a 600 g/1 solution of mepiquat chloride was placed in an agita ⁇ ted, jacketed, spray dryer feed tank and heated to 65°C with tem- pered water.
- the heated solution was pumped at 125 g/min to an atomizing wheel rotating at about 17,000 rpm in a spray dryer (a Niro Utility for example) .
- Silica (Sipernat® 50S) from a loss-in- weight screwfeeder was injected via an air eductor into the air plenum to mix with the heated air entering the plenum.
- the silica was fed at a rate of 4 wt.-% based on the dry basis feed rate of the mepiquat chloride solution.
- the silica/air mixture at 200°C, then entered the drying chamber, intermixing with the droplets formed by the atomizer.
- the resultant outlet temperature is about 140°C.
- On drying the powder exits the drying chamber does not ad- here to the walls of the spray dryer, the ducting, or the cyclone separator.
- the powder remains flowable in a polyethylene bag pak- ked in a sealed plastic drum.
- the resulting powder was flowable, had a moisture content of 0.25 wt.-%, a bulk density of 0.29 g/ml untapped, 0.38 g/ml tapped, and an ash content of about 2 wt.-%.
- the powder assayed at about 97 wt.-% mepiquat chloride.
- the resulting free flowing powder was composed of particles ran ⁇ ging from approximately 5 to 60 microns in diameter, with a moi ⁇ sture of about 0.08 wt.-%, and bulk density of 0.63 untapped and 0.79 tapped, and ash content of about 2 wt.-%.
- the powder assayed at about 97 wt.-% mepiquat chloride. There was no detectable me ⁇ piquat chloride in the overhead condensate.
- a mepiquat chloride powder prepared by the method of (example 8 for drum dryer) was tabletted (by a Carver press for example) . Press pressure was varied at 6 to 7 metric tons, 8 to 9 metric tons, and 10 to 11 metric tons for durations of 1 minute each.
- the formed tablets, of 2.26 inches in diameter, had thicknesses between 6.1 and 6.6 mm (0.24 and 0.26 inches) with weights of between 15.3 to 15.6 gms, with breaking strengths between 4 and 10 kgs (9 and 22.3 lbs) as determined on a modified Chatillon electronic tester, model DFI-50 mounted on a model LTC manual test stand.
- the tablets were dissolved in 750 ml of 342 ppm hard ⁇ ness water stirred with a magnetic stirring bar and dissolved completely in 0.9 to 4.7 minutes.
- a mepiquat chloride powder prepared by the method of (example 9 for the Littleford dryer) was tabletted (in a Carver press for example) . Press pressure was varied at 8 to 9 metric tons, and 10 to 11 metric tons for durations of 1 minute each.
- the formed ta ⁇ blets, of 2.26 inches in diameter, had thicknesses between 6.1 and 6.6 ms (0.24 and 0.26 inches) with weights of between 15.3 to 15.7 gms, with breaking strengths between 7.7 and 14.5 kgs (17 and 32 lbs) as determined on a modified Chatillon electronic te ⁇ ster, model DFI-50 mounted on a model LTC manual test stand.
- the tablets were dissolved in 750 ml of 342 ppm hardness water stir ⁇ red with a magnetic stirring bar and dissolved completely in 4.4 to 5.8 minutes.
- a mepiquat chloride powder prepared by the method of (example 7 for the spray dryer) was tabletted (in a Carver press for example) . Press pressure was varied at 6 to 7 metric tons, 8 to 9 metric tons, and 10 to 11 metric tons for durations of 1 minute each.
- the formed tablets, of 5.74 cms (2.26 inches) in diameter, had thicknesses between 5.8 and 7.1 mms (0.23 and 0.28 inches) with weights of between 14.4 to 15.7 gms, with breaking strengths between 7.48 and 24.9 kgs (16.5 and 55 lbs) as determined on a modified Chatillon electronic tester, model DFI-50 mounted on a model LTC manual test stand.
- the tablets were dissolved in 750 ml of 342 ppm hardness water stirred with a magnetic stirring bar and dissolved completely in 3.8 to 4.8 minutes.
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95122 | 1993-07-20 | ||
US08/095,122 US5468720A (en) | 1993-07-20 | 1993-07-20 | High concentrated, solid mepiquat chloride products and processes for making dry form solid mepiquat chloride powder and tablets |
PCT/EP1994/002253 WO1995002963A1 (en) | 1993-07-20 | 1994-07-09 | High concentrated, solid mepiquat chloride and chlormequat chloride products |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0710071A1 true EP0710071A1 (en) | 1996-05-08 |
EP0710071B1 EP0710071B1 (en) | 1997-10-01 |
Family
ID=22249834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94923717A Expired - Lifetime EP0710071B1 (en) | 1993-07-20 | 1994-07-09 | High concentrated, solid mepiquat chloride products |
Country Status (28)
Country | Link |
---|---|
US (3) | US5468720A (en) |
EP (1) | EP0710071B1 (en) |
JP (1) | JP3578764B2 (en) |
CN (1) | CN1062411C (en) |
AT (1) | ATE158686T1 (en) |
AU (1) | AU679773B2 (en) |
BR (1) | BR9407085A (en) |
CA (1) | CA2167513A1 (en) |
CO (1) | CO4340591A1 (en) |
CZ (1) | CZ292602B6 (en) |
DE (1) | DE69406005T2 (en) |
DK (1) | DK0710071T3 (en) |
ES (1) | ES2108482T3 (en) |
FI (1) | FI113149B (en) |
GR (1) | GR3025823T3 (en) |
HU (1) | HU215080B (en) |
IL (1) | IL110149A (en) |
NZ (1) | NZ269554A (en) |
PE (1) | PE33595A1 (en) |
PL (1) | PL177599B1 (en) |
RU (1) | RU2137367C1 (en) |
SK (1) | SK281625B6 (en) |
TJ (1) | TJ273B (en) |
TW (1) | TW307663B (en) |
UA (1) | UA34483C2 (en) |
UY (1) | UY23807A1 (en) |
WO (1) | WO1995002963A1 (en) |
ZA (1) | ZA945277B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2132187T3 (en) * | 1992-06-04 | 1999-08-16 | Micro Flo Co | MEPIQUAT CHLORIDE. |
US6013272A (en) | 1996-12-19 | 2000-01-11 | Valent U.S.A. Corporation | Chemically stable, insecticidally active phosphoroamidothioate pellet compositions and methods for their manufacture |
US6288009B1 (en) | 1998-04-10 | 2001-09-11 | Basf Corporation | Plant growth regulator compositions |
DE19825687A1 (en) * | 1998-06-09 | 1999-12-16 | Degussa | Active ingredient concentrate |
TW568788B (en) * | 1998-10-12 | 2004-01-01 | Chugai Pharmaceutical Co Ltd | Polymer combining with phosphoric acid and preparation containing the same |
WO2001058831A1 (en) * | 2000-02-08 | 2001-08-16 | Peter Warren English | A soil supplement containing plant available silicon |
US6410783B1 (en) | 2000-10-19 | 2002-06-25 | Basf Corporation | Method of producing carboxylic acid salts |
FR2833187B1 (en) * | 2001-12-11 | 2004-09-10 | Pancosma Sa Pour L Ind Des Pro | POWDER OLIGO-ELEMENT, METHOD AND DEVICE FOR ITS MANUFACTURE |
DK1453843T3 (en) * | 2001-12-11 | 2013-08-12 | Pancosma S A | Powder trace element, method and device for making them |
FR2843752B1 (en) * | 2002-08-26 | 2007-05-18 | Pancosma Sa Pour L Ind Des Pro | CRYSTALLINE OLIGO-ELEMENTS AND PROCESSES FOR THEIR MANUFACTURE |
US20040221631A1 (en) * | 2002-09-05 | 2004-11-11 | Kerrigan Kurt J. | Composition for fertilizer tablet |
US7325688B1 (en) | 2003-09-26 | 2008-02-05 | Gowan Milling Company, L.L.C. | Pressurized water-soluble pouch |
FR2935383B1 (en) * | 2008-08-26 | 2010-10-01 | Pancosma Sa Pour L Ind Des Pro | METHOD AND DEVICE FOR THE PRODUCTION OF ORGANOMETALLIC COMPLEXES IN POWDER. |
KR20130132555A (en) | 2010-12-21 | 2013-12-04 | 바이엘 크롭사이언스 엘피 | Sandpaper mutants of bacillus and methods of their use to enhance plant growth, promote plant health and control diseases and pests |
EP2755485A1 (en) | 2011-09-12 | 2014-07-23 | Bayer Cropscience LP | Methods of enhancing health and/or promoting growth of a plant and/or of improving fruit ripening |
CN103508784B (en) * | 2012-06-28 | 2015-07-08 | 马辉 | Pure natural plant growth regulator |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE101386C (en) * | ||||
US3356569A (en) * | 1964-05-27 | 1967-12-05 | Rohm & Haas | Choline chloride powder and method of production |
US3695989A (en) * | 1970-08-12 | 1972-10-03 | Robert E Albert | Cold water soluble foam plastic package |
BE795534A (en) * | 1972-02-18 | 1973-08-16 | Basf Ag | AGENTS FOR REGULATING PLANT GROWTH, CONTAINING NITROGEN SALT AS ACTIVE INGREDIENT |
DD101386A1 (en) * | 1972-12-21 | 1973-11-12 | ||
CH604880A5 (en) * | 1976-05-25 | 1978-09-15 | Ciba Geigy Ag | |
DE3926055A1 (en) * | 1989-08-07 | 1991-02-14 | Basf Ag | USE OF DIPHENYLETHER DERIVATIVES FOR DESICCATION AND ABSCISSION OF PLANT ORGANS |
US5222595A (en) * | 1990-07-18 | 1993-06-29 | Rhone-Poulenc Ag Company | Bag in a bag for containerization of toxic or hazardous material |
IL101539A (en) * | 1991-04-16 | 1998-09-24 | Monsanto Europe Sa | Non-hygroscopic mono-ammonium salts of n-phosphonomethyl glycine derivatives their preparation and pesticidal compositons containing them |
AU664997B2 (en) * | 1991-06-11 | 1995-12-14 | Rhone-Poulenc Agrochimie | New packaging/containerization system |
ES2132187T3 (en) * | 1992-06-04 | 1999-08-16 | Micro Flo Co | MEPIQUAT CHLORIDE. |
GEP20002202B (en) * | 1992-10-30 | 2000-08-25 | Basf Corp | Granular Water Soluble or Hygroscopic Agricultural Formulations and Methods of Making Them |
US5294594A (en) * | 1992-12-23 | 1994-03-15 | American Cyanamid Company | Water dispersible granular herbicidal compositions comprising dinitroaniline herbicides, montmorillonite carrier and water-swellable polymer |
-
1993
- 1993-07-20 US US08/095,122 patent/US5468720A/en not_active Expired - Lifetime
-
1994
- 1994-06-28 IL IL11014994A patent/IL110149A/en not_active IP Right Cessation
- 1994-07-08 TW TW083106224A patent/TW307663B/zh active
- 1994-07-09 PL PL94312658A patent/PL177599B1/en not_active IP Right Cessation
- 1994-07-09 DE DE69406005T patent/DE69406005T2/en not_active Expired - Fee Related
- 1994-07-09 CZ CZ1996159A patent/CZ292602B6/en not_active IP Right Cessation
- 1994-07-09 CA CA002167513A patent/CA2167513A1/en not_active Abandoned
- 1994-07-09 SK SK85-96A patent/SK281625B6/en unknown
- 1994-07-09 AU AU73852/94A patent/AU679773B2/en not_active Ceased
- 1994-07-09 AT AT94923717T patent/ATE158686T1/en not_active IP Right Cessation
- 1994-07-09 BR BR9407085A patent/BR9407085A/en not_active IP Right Cessation
- 1994-07-09 UA UA96020621A patent/UA34483C2/en unknown
- 1994-07-09 DK DK94923717.6T patent/DK0710071T3/en active
- 1994-07-09 TJ TJ96000265A patent/TJ273B/en unknown
- 1994-07-09 HU HU9503956A patent/HU215080B/en not_active IP Right Cessation
- 1994-07-09 ES ES94923717T patent/ES2108482T3/en not_active Expired - Lifetime
- 1994-07-09 JP JP50490095A patent/JP3578764B2/en not_active Expired - Fee Related
- 1994-07-09 WO PCT/EP1994/002253 patent/WO1995002963A1/en active IP Right Grant
- 1994-07-09 EP EP94923717A patent/EP0710071B1/en not_active Expired - Lifetime
- 1994-07-09 NZ NZ269554A patent/NZ269554A/en unknown
- 1994-07-09 CN CN94192833A patent/CN1062411C/en not_active Expired - Fee Related
- 1994-07-09 RU RU96103372/04A patent/RU2137367C1/en not_active IP Right Cessation
- 1994-07-14 CO CO94030971A patent/CO4340591A1/en unknown
- 1994-07-19 UY UY23807A patent/UY23807A1/en not_active IP Right Cessation
- 1994-07-19 ZA ZA945277A patent/ZA945277B/en unknown
- 1994-08-09 PE PE1994248169A patent/PE33595A1/en not_active Application Discontinuation
-
1995
- 1995-03-30 US US08/415,124 patent/US5589438A/en not_active Expired - Fee Related
- 1995-03-30 US US08/415,125 patent/US5523275A/en not_active Expired - Fee Related
-
1996
- 1996-01-19 FI FI960269A patent/FI113149B/en not_active IP Right Cessation
-
1997
- 1997-12-30 GR GR970403473T patent/GR3025823T3/en unknown
Non-Patent Citations (1)
Title |
---|
See references of WO9502963A1 * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU679773B2 (en) | High concentrated, solid mepiquat chloride and chlormequat chloride products | |
JPH08509485A (en) | Concentrated composition containing agricultural active ingredients | |
EP0665714B1 (en) | Granular water soluble or hygroscopic agricultural formulations and methods of making them | |
US5593948A (en) | Highly concentrated, solid acifluoren powders and processes for making dry form solid acifluorfen powders | |
MXPA96004978A (en) | Highly concentrated solid acifluorphene powders, and processes for manufacturing solid acifluorphene powders |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19951219 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19960430 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
RTI1 | Title (correction) | ||
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
REF | Corresponds to: |
Ref document number: 158686 Country of ref document: AT Date of ref document: 19971015 Kind code of ref document: T |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: SCHMAUDER & WANN PATENTANWALTSBUERO, INHABER KLAUS Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 |
|
REF | Corresponds to: |
Ref document number: 69406005 Country of ref document: DE Date of ref document: 19971106 |
|
ET | Fr: translation filed | ||
ITF | It: translation for a ep patent filed |
Owner name: ING. C. GREGORJ S.P.A. |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2108482 Country of ref document: ES Kind code of ref document: T3 |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: SC4A Free format text: AVAILABILITY OF NATIONAL TRANSLATION Effective date: 19971010 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed | ||
REG | Reference to a national code |
Ref country code: GB Ref legal event code: IF02 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: PT Payment date: 20040623 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20040704 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 20040706 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20040707 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20040708 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 20040713 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IE Payment date: 20040714 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DK Payment date: 20040715 Year of fee payment: 11 Ref country code: CH Payment date: 20040715 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20040719 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20040722 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GR Payment date: 20040727 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20040910 Year of fee payment: 11 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050709 Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050709 Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050709 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050710 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050711 Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050711 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050731 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050731 Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050731 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050801 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060109 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060201 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060201 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060202 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
EUG | Se: european patent has lapsed | ||
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20050709 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060331 |
|
NLV4 | Nl: lapsed or anulled due to non-payment of the annual fee |
Effective date: 20060201 |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: EBP |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20060331 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20050711 |
|
BERE | Be: lapsed |
Owner name: *BASF CORP. Effective date: 20050731 |