EP0662839A4 - ANTIGENIC VACCINES AND CONJUGATES. - Google Patents

ANTIGENIC VACCINES AND CONJUGATES.

Info

Publication number: EP0662839A4
Authority: EP; European Patent Office
Prior art keywords: hormone; fragment; epitope; immunologically equivalent; peptide
Prior art date: 1992-09-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP92921753A

Other languages

German (de)

English (en)

French (fr)

Other versions

EP0662839A1 (en

Inventor

Vernon C Stevens

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ohio State University Research Foundation

Original Assignee

Ohio State University Research Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-30

Filing date

1992-09-30

Publication date

1995-09-06

1992-09-30 Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation

1992-09-30 Priority to DE69233711T priority Critical patent/DE69233711D1/de

1992-09-30 Priority to EP01102609A priority patent/EP1129724B1/en

1995-07-19 Publication of EP0662839A1 publication Critical patent/EP0662839A1/en

1995-09-06 Publication of EP0662839A4 publication Critical patent/EP0662839A4/en

Status Ceased legal-status Critical Current

Links

230000000890 antigenic effect Effects 0.000 title abstract 3
229960005486 vaccine Drugs 0.000 title abstract 3
239000005556 hormone Substances 0.000 abstract 6
229940088597 hormone Drugs 0.000 abstract 6
239000012634 fragment Substances 0.000 abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 3
102000004169 proteins and genes Human genes 0.000 abstract 3
230000001850 reproductive effect Effects 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000003921 oil Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001144—Hormones, e.g. calcitonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Reproductive Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Zoology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Gynecology & Obstetrics (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Virology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP92921753A 1992-09-30 1992-09-30 ANTIGENIC VACCINES AND CONJUGATES. Ceased EP0662839A4 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
DE69233711T DE69233711D1 (de)	1992-09-30	1992-09-30	Impfstoffe zur Behandlung von Kolonkrebs
EP01102609A EP1129724B1 (en)	1992-09-30	1992-09-30	Vaccines for treating colon cancer

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1992/008370 WO1994007530A1 (en)	1992-09-30	1992-09-30	Vaccines and antigenic conjugates

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
EP01102609A Division EP1129724B1 (en)	1992-09-30	1992-09-30	Vaccines for treating colon cancer

Publications (2)

Publication Number	Publication Date
EP0662839A1 EP0662839A1 (en)	1995-07-19
EP0662839A4 true EP0662839A4 (en)	1995-09-06

Family

ID=25677857

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP01102609A Expired - Lifetime EP1129724B1 (en)	1992-09-30	1992-09-30	Vaccines for treating colon cancer
EP92921753A Ceased EP0662839A4 (en)	1992-09-30	1992-09-30	ANTIGENIC VACCINES AND CONJUGATES.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP01102609A Expired - Lifetime EP1129724B1 (en)	1992-09-30	1992-09-30	Vaccines for treating colon cancer

Country Status (7)

Country	Link
EP (2)	EP1129724B1 (ja)
JP (1)	JPH08502062A (ja)
AT (1)	ATE373486T1 (ja)
AU (1)	AU679902B2 (ja)
CA (1)	CA2145391A1 (ja)
DE (1)	DE69233711D1 (ja)
WO (1)	WO1994007530A1 (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5759551A (en) *	1993-04-27	1998-06-02	United Biomedical, Inc.	Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
GB9514816D0 (en)	1995-07-19	1995-09-20	Ucli Ltd	Substances and their medical use
US7053177B1 (en)	1997-05-15	2006-05-30	Cytogen Corporation	Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
US7135457B1 (en)	1997-05-15	2006-11-14	Cytogen Corporation	Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
US6703362B1 (en)	1997-05-15	2004-03-09	Cytogen Corporation	Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
WO2000041717A2 (en) *	1998-12-18	2000-07-20	Avi Biopharma, Inc.	Chorionic gonadotropin dna vaccines and methods
JP4658423B2 (ja) *	1999-08-03	2011-03-23	ザオハイオステイトユニバーシティ	Ｈｅｒ−２タンパク質に対する免疫反応性を増強するためのポリペプチドおよびポリヌクレオチド
JP2005508838A (ja)	2001-03-23	2005-04-07	アフトンコーポレーション	膵癌の組合せ治療
US20090191232A1 (en)	2001-05-04	2009-07-30	Gevas Philip C	Combination therapy for the treatment of tumors
US7235376B2 (en)	2003-03-28	2007-06-26	Receptor Biologix, Inc.	Gastrin hormone immunoassays
EP2567974A3 (en)	2004-09-22	2013-05-22	Cancer Advances, Inc.,	Monoclonal antibodies to progastrin
CN103169958A (zh) *	2005-02-04	2013-06-26	萨瓦克公司	存活蛋白肽疫苗
CA2612394C (en)	2005-06-15	2017-02-21	The Ohio State University Research Foundation	Her-2 peptides
US20100234283A1 (en)	2009-02-04	2010-09-16	The Ohio State University Research Foundation	Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
WO2011056226A1 (en) *	2009-11-05	2011-05-12	Mercia Pharma Llc	Adjuvanted nanoparticulate influenza vaccine
CA3066756A1 (en)	2017-06-15	2018-12-20	Cancer Advances Inc.	Compositions and methods for inducing humoral and cellular immunities against tumors and cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991000107A1 (fr) *	1989-07-03	1991-01-10	Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.)	Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
EP0427347A1 (en) *	1989-11-10	1991-05-15	ENIRICERCHE S.p.A.	Synthetic peptides useful as universal carriers for the preparation of immunogenic conjugates and their use in the development of synthetic vaccines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4762913A (en) *	1973-05-07	1988-08-09	The Ohio State University	Antigenic modification of polypeptides
US4201770A (en) *	1973-05-07	1980-05-06	The Ohio State University	Antigenic modification of polypeptides
US4302386A (en) *	1978-08-25	1981-11-24	The Ohio State University	Antigenic modification of polypeptides
US5006334A (en) *	1973-05-07	1991-04-09	The Ohio State University	Antigenic modification of polypeptides
US4384995A (en) *	1980-01-16	1983-05-24	The Ohio State University	Antigenic modification of polypeptides
US4526716A (en) *	1981-11-20	1985-07-02	The Ohio State University	Antigenic modification of polypeptides
US4691006A (en) *	1983-03-04	1987-09-01	Ohio State University	Antigenic modification of polypeptides
US4310455A (en) *	1979-04-17	1982-01-12	Research Corporation	Antigen for early pregnancy test and contraceptive vaccine
US4855285A (en) *	1985-12-04	1989-08-08	The Ohio State University Research Foundation	Antigenic modification of polypeptides
US4882145A (en) *	1986-12-09	1989-11-21	Scripps Clinic And Research Foundation	T cell epitopes of the hepatitis B virus nucleocapsid protein
US4886782A (en) *	1987-02-26	1989-12-12	The United States Of America As Represented By The Department Of Health And Human Services	Malarial immunogen

1992
- 1992-09-30 EP EP01102609A patent/EP1129724B1/en not_active Expired - Lifetime
- 1992-09-30 EP EP92921753A patent/EP0662839A4/en not_active Ceased
- 1992-09-30 DE DE69233711T patent/DE69233711D1/de not_active Expired - Fee Related
- 1992-09-30 AU AU28063/92A patent/AU679902B2/en not_active Expired
- 1992-09-30 WO PCT/US1992/008370 patent/WO1994007530A1/en not_active Application Discontinuation
- 1992-09-30 JP JP6508977A patent/JPH08502062A/ja active Pending
- 1992-09-30 CA CA002145391A patent/CA2145391A1/en not_active Abandoned
- 1992-09-30 AT AT01102609T patent/ATE373486T1/de not_active IP Right Cessation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991000107A1 (fr) *	1989-07-03	1991-01-10	Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.)	Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
EP0427347A1 (en) *	1989-11-10	1991-05-15	ENIRICERCHE S.p.A.	Synthetic peptides useful as universal carriers for the preparation of immunogenic conjugates and their use in the development of synthetic vaccines

Also Published As

Publication number	Publication date
JPH08502062A (ja)	1996-03-05
EP1129724B1 (en)	2007-09-19
EP1129724A2 (en)	2001-09-05
EP1129724A3 (en)	2001-11-07
DE69233711D1 (de)	2007-10-31
ATE373486T1 (de)	2007-10-15
WO1994007530A1 (en)	1994-04-14
AU679902B2 (en)	1997-07-17
AU2806392A (en)	1994-04-26
EP0662839A1 (en)	1995-07-19
CA2145391A1 (en)	1994-04-14

Legal Events

Date	Code	Title	Description
1995-06-02	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-07-19	17P	Request for examination filed	Effective date: 19950324
1995-07-19	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE
1995-09-06	A4	Supplementary search report drawn up and despatched
1995-09-06	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE
1996-01-10	RHK1	Main classification (correction)	Ipc: A61K 39/00
1996-12-18	17Q	First examination report despatched	Effective date: 19961104
1998-07-07	APAB	Appeal dossier modified	Free format text: ORIGINAL CODE: EPIDOS NOAPE
1998-09-09	APAB	Appeal dossier modified	Free format text: ORIGINAL CODE: EPIDOS NOAPE
1998-10-14	APAD	Appeal reference recorded	Free format text: ORIGINAL CODE: EPIDOS REFNE
2001-09-25	APAB	Appeal dossier modified	Free format text: ORIGINAL CODE: EPIDOS NOAPE
2001-09-28	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2001-11-14	18R	Application refused	Effective date: 19980507
2005-10-05	APAF	Appeal reference modified	Free format text: ORIGINAL CODE: EPIDOSCREFNE

Publication	Publication Date	Title
EP0662839A4 (en)	1995-09-06	ANTIGENIC VACCINES AND CONJUGATES.
GB2303855B (en)	1998-10-28	Helicobacter pylori antigenic protein preparation and immunoassays
AUPP807399A0 (en)	1999-02-04	Improved immunogenic lhrh composition and methods relating thereto
HU9502201D0 (en)	1995-09-28	Ganglioside-klh conjugate vaccines with qs-21
GR3035081T3 (en)	2001-03-30	Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
EP0716613A4 (en)	1998-05-20	TREATING A GASTRODUODENAL DISEASE CAUSED BY -i (HELICOBAKTER PYLORI)
AU6714290A (en)	1991-04-28	Method of treating infectious bursal disease virus
EP0651653A4 (en)	1996-07-17	VACCINE p53.
EP0881910A4 (en)	2006-05-03	USE OF IMMUNOCONJUGATES TO ENHANCE THE EFFICACY OF MULTI-STEP VACCINES STIMULATING IMMUNE REACTIONS IN CASCADE
GR3019356T3 (en)	1996-06-30	Recombinant mycoplasma hyopneumoniae antigen and uses therefor
GR3029727T3 (en)	1999-06-30	Synthetic peptides and vaccines against parvovirus.
EP0282501A1 (en)	1988-09-21	Regulating animal reproduction
AU673344B2 (en)	1996-11-07	Vaccines based on streptokinase
PT101264A (pt)	1994-06-30	Dispositivo de vacinacao de coelhos por via parenterica contra a enterotoxemia do coelho e vacina a base de anotoxina de clostridium spiroforme condicionada para utilizacao nesse dispositivo
DE69322960D1 (de)	1999-02-18	Empfängnisverhütender impfstoff
GR3026715T3 (en)	1998-07-31	Reduced-protein subunit vaccine for swine dysentery
de Pilar	1982	Antibodies for developing adolescents and children. Conclusions for vaccinations against rubella, measles, mumps, diphtheria and tetanus.).
DE69012328D1 (de)	1994-10-13	Srif-verwandte peptide und deren verwendungen.
MX9700215A (es)	1998-01-31	Proteinas y vacunas de helicobacter.