EP0603314A4 - Chemical compounds. - Google Patents
Chemical compounds.Info
- Publication number
- EP0603314A4 EP0603314A4 EP9292920317A EP92920317A EP0603314A4 EP 0603314 A4 EP0603314 A4 EP 0603314A4 EP 9292920317 A EP9292920317 A EP 9292920317A EP 92920317 A EP92920317 A EP 92920317A EP 0603314 A4 EP0603314 A4 EP 0603314A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919119467A GB9119467D0 (en) | 1991-09-12 | 1991-09-12 | Chemical compounds |
GB9119467 | 1991-09-12 | ||
PCT/US1992/007694 WO1993004686A1 (en) | 1991-09-12 | 1992-09-11 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0603314A1 EP0603314A1 (en) | 1994-06-29 |
EP0603314A4 true EP0603314A4 (en) | 1994-08-24 |
Family
ID=10701273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP9292920317A Ceased EP0603314A4 (en) | 1991-09-12 | 1992-09-11 | Chemical compounds. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0603314A4 (en) |
JP (1) | JPH06510545A (en) |
AU (1) | AU2654792A (en) |
GB (1) | GB9119467D0 (en) |
WO (1) | WO1993004686A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999007353A1 (en) * | 1997-08-05 | 1999-02-18 | The Mount Sinai School Of Medicine Of The City University Of New York | USE OF α1A-ADRENERGIC RECEPTOR ANTAGONISTS IN GLAUCOMA THERAPY |
US6395736B1 (en) * | 1998-12-14 | 2002-05-28 | Cellegy Pharmaceuticals, Inc. | Compositions and methods for the treatment of anorectal disorders |
WO2003042190A1 (en) | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
PA8557501A1 (en) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | BENZAMIDA, HETEROARILAMIDA AND INVESTED AMIDAS |
RU2423353C1 (en) | 2002-12-20 | 2011-07-10 | Глэксо Груп Лимитед | New benzazepin derivatives |
PA8591801A1 (en) | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | BENZAMID INHIBITORS OF THE P2X7 RECEIVER. |
US7071223B1 (en) | 2002-12-31 | 2006-07-04 | Pfizer, Inc. | Benzamide inhibitors of the P2X7 receptor |
JP4731468B2 (en) | 2003-05-12 | 2011-07-27 | ファイザー・プロダクツ・インク | Benzamide inhibitor of P2X7 receptor |
AU2004283452A1 (en) * | 2003-10-23 | 2005-05-06 | F. Hoffmann-La Roche Ag | Benzazepine derivatives as MAO-B inhibitors |
EP1720836B1 (en) | 2004-02-25 | 2014-04-16 | Eli Lilly And Company | 6-substituted 2,3,4,5-tetrahydro-1h-benzo [d]azepines as 5-ht2c receptor agonists |
AU2005258911A1 (en) | 2004-06-29 | 2006-01-12 | Pfizer Products Inc. | Method for preparing 5-`4-(2-hydroxy-propyl)-3,5-dioxo-4,5-dihydro-3H`1,2,4!triazin-2-YL!-benzamide derivatives by deprotecting the hydroxyl-protected precursers |
ES2397400T3 (en) | 2005-09-01 | 2013-03-06 | Eli Lilly & Company | 6-arylalkylamino-2,3,4,5-tetrahydro-1H-benzo [D] azepines as 5-HT2C receptor agonists |
PT1926712E (en) | 2005-09-01 | 2009-10-06 | Lilly Co Eli | 6-substituted 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists |
WO2007028082A1 (en) * | 2005-09-01 | 2007-03-08 | Eli Lilly And Company | 6-substituted- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists |
ES2440483T3 (en) | 2005-09-01 | 2014-01-29 | Eli Lilly And Company | 2,3,4,5-Tetrahydro-1H-benzo [d] azepines substituted with 6-N-linked heterocycle as 5-HT2C receptor agonists |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0285287A2 (en) * | 1987-03-23 | 1988-10-05 | Smithkline Beecham Corporation | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3483185A (en) * | 1966-08-16 | 1969-12-09 | American Home Prod | N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines |
ZA792785B (en) * | 1978-07-07 | 1980-08-27 | Smithkline Corp | Mercapto substituted-2,3,4,5-tetrahydro-1h-3-benzazepines |
US4469634A (en) * | 1982-07-29 | 1984-09-04 | Smithkline Beckman Corporation | Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines |
US4683229A (en) * | 1986-03-17 | 1987-07-28 | Smithkline Beckman Corporation | 6-halo-9-alkenyleneoxy-3-alkyl-2,3,4,5-tetrahydro-(1H-3)-benzazepines and their use as selective alpha-adrenergic receptor antagonists |
-
1991
- 1991-09-12 GB GB919119467A patent/GB9119467D0/en active Pending
-
1992
- 1992-09-11 WO PCT/US1992/007694 patent/WO1993004686A1/en not_active Application Discontinuation
- 1992-09-11 JP JP5505509A patent/JPH06510545A/en active Pending
- 1992-09-11 EP EP9292920317A patent/EP0603314A4/en not_active Ceased
- 1992-09-11 AU AU26547/92A patent/AU2654792A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0285287A2 (en) * | 1987-03-23 | 1988-10-05 | Smithkline Beecham Corporation | 3-Benzazepine compounds for use in treating gastrointestinal motility disorders |
Non-Patent Citations (2)
Title |
---|
LADD, DAVID L.; WEINSTOCK, JOSEPH; WISE, MARGARET; GESSNER, GEORGE W.; SAWYER, JOHN L.; FLAIM, KATHRYN E.: "Synthesis and dopaminergic binding of 2-aryldopamine analogs: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes", JOURNAL OF MEDICINAL CHEMISTRY., vol. 29, no. 10, WASHINGTON US, pages 1904 - 1912, XP002031848, DOI: doi:10.1021/jm00160a018 * |
See also references of WO9304686A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2654792A (en) | 1993-04-05 |
EP0603314A1 (en) | 1994-06-29 |
WO1993004686A1 (en) | 1993-03-18 |
GB9119467D0 (en) | 1991-10-23 |
JPH06510545A (en) | 1994-11-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19940316 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE CH DE FR GB IT LI NL |
|
RHK1 | Main classification (correction) |
Ipc: C07D223/16 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19940705 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): BE CH DE FR GB IT LI NL |
|
17Q | First examination report despatched |
Effective date: 19970424 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 19981205 |