EP0505552A4 - Megakaryocyte maturation factors - Google Patents

Megakaryocyte maturation factors

Info

Publication number
EP0505552A4
EP0505552A4 EP19910919689 EP91919689A EP0505552A4 EP 0505552 A4 EP0505552 A4 EP 0505552A4 EP 19910919689 EP19910919689 EP 19910919689 EP 91919689 A EP91919689 A EP 91919689A EP 0505552 A4 EP0505552 A4 EP 0505552A4
Authority
EP
European Patent Office
Prior art keywords
maturation factors
megakaryocyte maturation
megakaryocyte
factors
maturation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910919689
Other versions
EP0505552A1 (en
Inventor
Pamela Hunt
Tsutomu Arakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of EP0505552A1 publication Critical patent/EP0505552A1/en
Publication of EP0505552A4 publication Critical patent/EP0505552A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP19910919689 1990-10-12 1991-10-02 Megakaryocyte maturation factors Withdrawn EP0505552A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59645790A 1990-10-12 1990-10-12
US596457 1990-10-12

Publications (2)

Publication Number Publication Date
EP0505552A1 EP0505552A1 (en) 1992-09-30
EP0505552A4 true EP0505552A4 (en) 1994-06-08

Family

ID=24387345

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910919689 Withdrawn EP0505552A4 (en) 1990-10-12 1991-10-02 Megakaryocyte maturation factors

Country Status (8)

Country Link
EP (1) EP0505552A4 (en)
JP (1) JPH05503302A (en)
AU (1) AU8868891A (en)
CA (1) CA2071479A1 (en)
IE (1) IE913601A1 (en)
IL (1) IL99648A0 (en)
WO (1) WO1992006712A1 (en)
ZA (1) ZA918070B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922572A (en) * 1994-01-25 1999-07-13 Human Genome Sciences, Inc. Polynucleotides encoding haemopoietic maturation factor
EE9600121A (en) * 1994-03-31 1997-04-15 Amgen Inc. Compositions and methods for stimulating megakaryocyte growth and differentiation
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
DE69733694T2 (en) 1996-07-10 2006-07-06 Muramatsu, Takashi, Nagoya USE OF PROTEINS FROM THE MK FAMILY AS A HEMATOPOIETIC FACTOR
US8404716B2 (en) 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US11116782B2 (en) 2002-10-15 2021-09-14 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US7189740B2 (en) 2002-10-15 2007-03-13 Celgene Corporation Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes
US8404717B2 (en) 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes using lenalidomide
AP2138A (en) * 2004-04-14 2010-07-22 Celgene Corp Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes.
AU2004319758A1 (en) * 2004-04-14 2005-11-24 Celgene Corporation Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
EA201790439A1 (en) 2014-08-22 2017-07-31 Селджин Корпорейшн METHODS OF TREATING MULTIPLE MYELOMA WITH THE USE OF IMMUNOMODULATING COMPOUNDS IN COMBINATION WITH ANTIBODIES

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2146335A (en) * 1983-09-07 1985-04-17 Ej Ass Inc Wound healing compositions
WO1990000606A1 (en) * 1988-07-13 1990-01-25 Brigham And Women's Hospital Polynucleotides that encode the human proteoglycan peptide core of the effector cells of the immune response
EP0354989A1 (en) * 1988-06-28 1990-02-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Megakaryocytopoietin, preparation and use
WO1990012108A1 (en) * 1989-04-03 1990-10-18 Genetics Institute, Inc. Megakaryocyte growth promoting activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4894440A (en) * 1986-09-17 1990-01-16 Massachusetts Institute Of Technology Method of isolating megakaryocyte stimulatory factor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2146335A (en) * 1983-09-07 1985-04-17 Ej Ass Inc Wound healing compositions
EP0354989A1 (en) * 1988-06-28 1990-02-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Megakaryocytopoietin, preparation and use
WO1990000606A1 (en) * 1988-07-13 1990-01-25 Brigham And Women's Hospital Polynucleotides that encode the human proteoglycan peptide core of the effector cells of the immune response
WO1990012108A1 (en) * 1989-04-03 1990-10-18 Genetics Institute, Inc. Megakaryocyte growth promoting activity

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LYNNE WILLIAMS ET AL.: "REGULATION OF IN VITRO HUMAN MEGAKARYOCYTE MATURATION", PROG. CLIN. BIOL. RES. (NR MOLECULAR BIOLOGY AND DIFFERENTIATION OF MEGAKARYOCYTES), vol. 356, 1990, pages 181 - 198, XP000677785 *
See also references of WO9206712A1 *

Also Published As

Publication number Publication date
IL99648A0 (en) 1992-08-18
CA2071479A1 (en) 1992-04-13
AU8868891A (en) 1992-05-20
WO1992006712A1 (en) 1992-04-30
ZA918070B (en) 1992-07-29
JPH05503302A (en) 1993-06-03
EP0505552A1 (en) 1992-09-30
IE913601A1 (en) 1992-04-22

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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