EP0439527A4 - A process for producing l-phenyl acetyl carbinol (pac), an immobilized cell mass for use in the process and a method for preparing the cell mass - Google Patents

A process for producing l-phenyl acetyl carbinol (pac), an immobilized cell mass for use in the process and a method for preparing the cell mass

Info

Publication number
EP0439527A4
EP0439527A4 EP19890912199 EP89912199A EP0439527A4 EP 0439527 A4 EP0439527 A4 EP 0439527A4 EP 19890912199 EP19890912199 EP 19890912199 EP 89912199 A EP89912199 A EP 89912199A EP 0439527 A4 EP0439527 A4 EP 0439527A4
Authority
EP
European Patent Office
Prior art keywords
cell mass
pac
preparing
producing
phenyl acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890912199
Other versions
EP0439527A1 (en
Inventor
Robert J. Seely
Donald L. Heefner
Robert V. Hageman
Michael J. Yarus
Sally A. Sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Boulder Inc
Original Assignee
Synergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synergen Inc filed Critical Synergen Inc
Publication of EP0439527A1 publication Critical patent/EP0439527A1/en
Publication of EP0439527A4 publication Critical patent/EP0439527A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19890912199 1988-10-21 1989-10-13 A process for producing l-phenyl acetyl carbinol (pac), an immobilized cell mass for use in the process and a method for preparing the cell mass Withdrawn EP0439527A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26062288A 1988-10-21 1988-10-21
US260622 1988-10-21

Publications (2)

Publication Number Publication Date
EP0439527A1 EP0439527A1 (en) 1991-08-07
EP0439527A4 true EP0439527A4 (en) 1991-11-21

Family

ID=22989911

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890912199 Withdrawn EP0439527A4 (en) 1988-10-21 1989-10-13 A process for producing l-phenyl acetyl carbinol (pac), an immobilized cell mass for use in the process and a method for preparing the cell mass

Country Status (5)

Country Link
EP (1) EP0439527A4 (en)
JP (1) JPH04502104A (en)
AU (1) AU4501989A (en)
CA (1) CA2000721A1 (en)
WO (1) WO1990004639A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079145A (en) * 1988-10-21 1992-01-07 Synergen Associates, Inc. Process for preparing microorganisms used for making phenyl acetyl carlinol (pac)
AUPP388298A0 (en) * 1998-06-03 1998-06-25 Polychip Pharmaceuticals Pty Ltd Precursers of pharmaceutical compounds
AUPQ462599A0 (en) 1999-12-13 2000-01-13 Polychip Pharmaceuticals Pty Ltd Yeast-based process for production of l-pac
DE10032058A1 (en) * 2000-07-05 2002-01-17 Basf Ag Microbial production of R-phenylacetylcarbinol by biological conversion of benzaldehyde by filamentous fungi
DE10142574A1 (en) 2001-09-01 2003-03-20 Basf Ag Process for the preparation of R-phenylacetylcarbinol by an enzymatic process in a two-phase system
WO2007077141A1 (en) * 2006-01-06 2007-07-12 Basf Aktiengesellschaft Method for producing substituted phenylacetyl carbinols
KR20140127159A (en) * 2013-04-24 2014-11-03 후지필름 가부시키가이샤 Filtration filter, filtering method, cellulose acylate film and method of producing the same
DE102017210944B4 (en) 2017-06-28 2019-05-23 Technische Universität Dresden Alcohol dehydrogenases and methods for the stereoselective reduction of carbonyl compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338796A (en) * 1966-10-13 1967-08-29 Merck & Co Inc Converting veratraldehyde to l(-)3, 4-dimethoxyphenylacetyl carbinol
CH564602A5 (en) * 1973-01-10 1975-07-31 Battelle Memorial Institute Method and device for the continuous control of the course of an enzyme reaction
US4436813A (en) * 1982-03-16 1984-03-13 Purification Engineering, Inc. Immobilized microbial cell composition for making L-aspartic acid
US4732851A (en) * 1982-03-16 1988-03-22 Purification Engineering, Inc. Immobilization of cells with a polyazetidine prepolymer
US4728611A (en) * 1983-07-29 1988-03-01 Purification Engineering, Inc. Production of phenylalanine with immobilized cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9004639A1 *

Also Published As

Publication number Publication date
EP0439527A1 (en) 1991-08-07
CA2000721A1 (en) 1990-04-21
WO1990004639A1 (en) 1990-05-03
JPH04502104A (en) 1992-04-16
AU4501989A (en) 1990-05-14

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: SEELY, ROBERT, J.

Inventor name: SULLIVAN, SALLY, A.

Inventor name: HEEFNER, DONALD, L.

Inventor name: HAGEMAN, ROBERT, V.

Inventor name: YARUS, MICHAEL, J.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930501