EP0416694B1 - Liquid drop dispensing tip - Google Patents

Liquid drop dispensing tip Download PDF

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Publication number
EP0416694B1
EP0416694B1 EP90202323A EP90202323A EP0416694B1 EP 0416694 B1 EP0416694 B1 EP 0416694B1 EP 90202323 A EP90202323 A EP 90202323A EP 90202323 A EP90202323 A EP 90202323A EP 0416694 B1 EP0416694 B1 EP 0416694B1
Authority
EP
European Patent Office
Prior art keywords
orifice
liquid drop
dispensing tip
delivery
drop dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP90202323A
Other languages
German (de)
French (fr)
Other versions
EP0416694A1 (en
Inventor
Leonid Bunin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0416694A1 publication Critical patent/EP0416694A1/en
Application granted granted Critical
Publication of EP0416694B1 publication Critical patent/EP0416694B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers

Definitions

  • This invention is concerned with a novel design of a dropper tip useful on conventional medicine droppers used primarily for dispensing ophthalmic medications.
  • the conventional ophthalmic drug delivery system consisting of a dropper tip, 1, and squeeze bottle, 2, is intended to deliver the medication in a drop by drop manner, the drops being of a uniform predetermined size.
  • the drop size control is achieved by means of the hydraulic resistence presented by a small diameter channel, 3, forming the beginning of the straight delivery channel, 4, in the dropper tip, 1, having a diameter of about 0.006 inches or 0.150 mm. which restricts the flow from the squeeze bottle, 2.
  • This conventional drug delivery system generally serves the intended purpose but in the hands of many patients does not always result in discrete drops but rather streaming of the liquid resulting in loss of medication, and possibly soiled clothes and other fabrics.
  • a dropper tip providing better delivery control, that requires a lower level of technology to fabricate, thus lowering the cost per unit device, and permitting fabrication practically anywhere in the world.
  • the restriction to flow or hydraulic resistance is provided, not by a narrow channel that is difficult to fabricate, but in part by a convoluted delivery path causing the liquid flow to change direction as it enters the delivery channel which impedes the conversion of the internal static energy provided by squeezing of the bottle into the kinetic energy of the liquid flow.
  • the cross-section of the orifice can be of any shape such as circular, triangular, semicircular, irregular or rectangular, preferably the latter, in which case the hydraulic resistance to fluid delivery is determined in part by the dimensions of the rectangle a long and narrow rectangular orifice providing greater hydraulic resistance than a square orifice of the same cross-section area.
  • the orifice has a cross-sectional area of about 0.015 to 0.02 mm2.
  • the size and shape of the orifice, 7, can be controlled by simplified molding techniques within desired specifications.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Description

    DETAILED DESCRIPTION OF THE INVENTION
  • This invention is concerned with a novel design of a dropper tip useful on conventional medicine droppers used primarily for dispensing ophthalmic medications.
  • The conventional ophthalmic drug delivery system, FIG. 1, consisting of a dropper tip, 1, and squeeze bottle, 2, is intended to deliver the medication in a drop by drop manner, the drops being of a uniform predetermined size. The drop size control is achieved by means of the hydraulic resistence presented by a small diameter channel, 3, forming the beginning of the straight delivery channel, 4, in the dropper tip, 1, having a diameter of about 0.006 inches or 0.150 mm. which restricts the flow from the squeeze bottle, 2. This conventional drug delivery system generally serves the intended purpose but in the hands of many patients does not always result in discrete drops but rather streaming of the liquid resulting in loss of medication, and possibly soiled clothes and other fabrics.
  • In addition conventional dropper tips with the narrow channel, 3, are commonly fabricated from plastics by injection molding techniques which require a complex technology not readily available in less developed countries.
  • Both EP-A-0 378 935 and GB-A-874 952 disclose dropper devices which have orifices that are not concentric with the delivery channel.
  • Now with the present invention there is provided a dropper tip providing better delivery control, that requires a lower level of technology to fabricate, thus lowering the cost per unit device, and permitting fabrication practically anywhere in the world.
  • These advantages are achieved by the design of the tip, 5, shown in Fig. 2, wherein entry to the delivery channel, 6, is not through a narrow channel, but rather through an orifice, 7, which is not concentric with the delivery channel but rather at an angle, preferably right angle, to it on the side of the hub, 8.
  • In the novel tip of this invention the restriction to flow or hydraulic resistance, is provided, not by a narrow channel that is difficult to fabricate, but in part by a convoluted delivery path causing the liquid flow to change direction as it enters the delivery channel which impedes the conversion of the internal static energy provided by squeezing of the bottle into the kinetic energy of the liquid flow.
  • In addition, the cross-section of the orifice can be of any shape such as circular, triangular, semicircular, irregular or rectangular, preferably the latter, in which case the hydraulic resistance to fluid delivery is determined in part by the dimensions of the rectangle a long and narrow rectangular orifice providing greater hydraulic resistance than a square orifice of the same cross-section area. Regardless of shape, the orifice has a cross-sectional area of about 0.015 to 0.02 mm².
  • The size and shape of the orifice, 7, can be controlled by simplified molding techniques within desired specifications.

Claims (4)

  1. A dropper tip (1) for the controlled, non-streaming delivery of discrete drops of a liquid, providing entry to the delivery channel (6) by an orifice (7) that is not concentric with the delivery channel (6), wherein the orifice (7) has a cross-sectional area of about 0.015 to 0.02 mm².
  2. The dropper tip of claim 1, wherein the cross-section of the orifice (7) is non-circular.
  3. The dropper tip of claim 1 or claim 2, wherein the orifice (7) is at a right angle to the delivery channel (6).
  4. The dropper tip of any one of the preceding claims, wherein the cross-section of the orifice (7) is rectangular in shape.
EP90202323A 1989-09-08 1990-09-01 Liquid drop dispensing tip Expired - Lifetime EP0416694B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40454089A 1989-09-08 1989-09-08
US404540 1989-09-08

Publications (2)

Publication Number Publication Date
EP0416694A1 EP0416694A1 (en) 1991-03-13
EP0416694B1 true EP0416694B1 (en) 1994-07-13

Family

ID=23600011

Family Applications (1)

Application Number Title Priority Date Filing Date
EP90202323A Expired - Lifetime EP0416694B1 (en) 1989-09-08 1990-09-01 Liquid drop dispensing tip

Country Status (4)

Country Link
EP (1) EP0416694B1 (en)
JP (1) JPH069599B2 (en)
CA (1) CA2024673A1 (en)
DE (1) DE69010597T2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009079753A1 (en) * 2007-12-21 2009-07-02 Pharmascience Inc. Pharmaceutical delivery device

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720997U (en) * 1993-09-21 1995-04-18 山崎産業株式会社 Western style handrail device
US6098852A (en) * 1999-01-27 2000-08-08 Automatic Liquid Packaging, Inc. Tip for liquid drop dispensing container
JP3922910B2 (en) * 2001-10-31 2007-05-30 参天製薬株式会社 Eye drops container with stepped part
ATE301586T1 (en) * 2001-11-30 2005-08-15 Crown Packaging Technology Inc A CLOSURE
JP7066134B2 (en) * 2017-08-04 2022-05-13 クラレノリタケデンタル株式会社 Liquid pouring materials and containers
WO2019027025A1 (en) 2017-08-04 2019-02-07 クラレノリタケデンタル株式会社 Member for discharging liquid and container

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222944A1 (en) * 1985-11-07 1987-05-27 Delford O. Dougherty Drop dispenser
EP0312725A2 (en) * 1987-10-23 1989-04-26 Bernd Dipl.-Ing. Hansen Drop dispersing bottle and process for making it
EP0378935A1 (en) * 1988-12-20 1990-07-25 Societe Technique De Pulverisation (S.T.E.P.) Device to dispense a liquid or cream in droplets having small volumes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2834520A (en) * 1956-06-15 1958-05-13 Nyden Robert Spouts for containers
GB874952A (en) * 1960-05-30 1961-08-16 Anchor Glass Company Ltd A dropper device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0222944A1 (en) * 1985-11-07 1987-05-27 Delford O. Dougherty Drop dispenser
EP0312725A2 (en) * 1987-10-23 1989-04-26 Bernd Dipl.-Ing. Hansen Drop dispersing bottle and process for making it
EP0378935A1 (en) * 1988-12-20 1990-07-25 Societe Technique De Pulverisation (S.T.E.P.) Device to dispense a liquid or cream in droplets having small volumes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009079753A1 (en) * 2007-12-21 2009-07-02 Pharmascience Inc. Pharmaceutical delivery device

Also Published As

Publication number Publication date
CA2024673A1 (en) 1991-03-09
DE69010597T2 (en) 1995-01-26
DE69010597D1 (en) 1994-08-18
JPH03111052A (en) 1991-05-10
EP0416694A1 (en) 1991-03-13
JPH069599B2 (en) 1994-02-09

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