EP0257052A1 - Device for therapeutical irradiation of organic tissue by laser radiation - Google Patents

Device for therapeutical irradiation of organic tissue by laser radiation

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Publication number
EP0257052A1
EP0257052A1 EP87901050A EP87901050A EP0257052A1 EP 0257052 A1 EP0257052 A1 EP 0257052A1 EP 87901050 A EP87901050 A EP 87901050A EP 87901050 A EP87901050 A EP 87901050A EP 0257052 A1 EP0257052 A1 EP 0257052A1
Authority
EP
European Patent Office
Prior art keywords
laser
radiation
irradiation
wavelength
field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP87901050A
Other languages
German (de)
French (fr)
Inventor
Gerhard Müller
Peter Greve
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carl Zeiss AG
Original Assignee
Carl Zeiss AG
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Filing date
Publication date
Application filed by Carl Zeiss AG filed Critical Carl Zeiss AG
Publication of EP0257052A1 publication Critical patent/EP0257052A1/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/073—Radiation therapy using light using polarised light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0614—Tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light

Definitions

  • the present invention relates to a device for the therapeutic irradiation of organic tissue according to the preamble of claim 1.
  • Such devices have become known as so-called mid or soft lasers. They are used for treatment in various fields, for example in rheumatology, dermatology, neurclogy or in dental medicine. Treatment with laser beams is painless and does not cause warming or a micro-chemical change in the tissue.
  • the laser radiation has a stimulating effect on cell activities and thus activates the body's own healing powers; Above all, it has an anti-inflammatory, anti-dreary and pain-relieving effect and is free of any side effects.
  • Mid lasers which contain a HeNe laser which emits radiation with a wavelength of 633 nm. This radiation is fed to the location of the radiation via flexible glass fibers. The originally polarized laser radiation is depolarized. Such lasers are preferably used for wound treatment.
  • Mid lasers are also known which additionally contain a second laser which emits radiation with a wavelength of 904 nm.
  • the beam is fed directly to the radiation site, i.e. without the interposition of optical elements. This makes such a device very difficult to handle.
  • the laser beam is guided over the radiation field in the form of a scanning grid.
  • This has the disadvantage that the power density is unevenly distributed over this field, since it is higher in and near the reversal points than in the areas in between.
  • this is pulsed, the pulse frequency being adjustable and reaching up to about 5 kHz in the upper range.
  • the semiconductor diodes used in this case only emit a low power on average over time, which is generally about 5 mW and below.
  • the laser working in the near infrared range emits radiation from the wavelength range 800-870 nm, preferably at 840 nm.
  • This radiation is emitted in continuous beam mode and expanded by an optical system to a desired diameter at the location of the radiation.
  • the laser which is advantageously designed as a GaAs semiconductor diode, emitting an average power of approximately 100 mW.
  • This enzyme absorbs photons from the incident laser radiation and these cause, among other things. a load carrier exchange.
  • Zeil membranes polarize and thus stimulate cell metabolism.
  • the continuous irradiation of the laser radiation has the effect that a certain number of photons per unit area and time is available at every point in the radiation field. With each occurrence of the abovementioned briefly existing absorption state of the enzyme, a sufficient number of photons are available in the wavelength range optimal for absorption, so that stimulation of the cell metabolism can take place. Since the power density of the radiation is evenly distributed over the irradiated field, the stimulating effects occur evenly distributed over this field.
  • the laser radiation is supplied to the radiation field via mirrors. This ensures that the polarized radiation emitted by the HeNe laser is not depolarized on its way to the radiation field, ie that it actually strikes it as polarized radiation. It has been found that by the closure of the wound is accelerated, so that 'acts, the apparatus highly stimulating to the Ephitelgewebe.
  • mirrors also allows the beam delivery to be designed very flexibly, so that it is easy to position the radiation field on the body to be treated.
  • the device according to the invention particularly advantageously contains an arrangement for internal power measurement.
  • This arrangement continuously displays the power of the emitted laser radiation and thus enables precise metering of the laser radiation striking the radiation field.
  • an LCD panel is advantageously arranged in the beam path in the device according to the invention.
  • the degree of alignment of the LCD crystals and thus the absorption of the polarized laser radiation can be controlled in a particularly simple manner by means of the voltage applied to the LCD plate.
  • Figure 1 shows the optical beam path in a schematic representation.
  • Fig. 2 is a perspective view of the device.
  • (1) denotes a HeNe laser emitting at ⁇ 33 nm.
  • the polarized radiation emitted by this passes through an LCD panel (2).
  • This plate consists of a thin liquid crystal layer which is arranged between two glass plates provided with transparent electrodes. A controllable voltage is applied between these electrodes via a control arrangement (3). The magnitude of this voltage regulates the intensity of the radiation passing through the plate (2).
  • a splitter mirror (4) is arranged behind the LCD plate (2), via which the radiation emitted by the laser diode (5) enters the beam path.
  • the laser diode (5) is designed as a GaAs diode, which emits at 840 nm and which operates in continuous wave (continuous wave) mode.
  • a condenser system (6) is used to generate a parallel beam path. Behind the mirror (4), the radiation emitted by the lasers (1 and 2) runs coaxially over the same radiation path and is influenced by the same components.
  • a partially reflecting mirror (7) is arranged in this beam path and directs a small percentage of the incident radiation onto a detector (8). This is followed by an amplifier (9) and a display instrument (10). This shows the power in the laser beam path.
  • the laser beam path is deflected via a mirror (11) which is arranged in a tubular housing (12) which can be rotated about an axis coinciding with the optical axis (13).
  • An optical system for beam expansion is arranged in the housing (12), which in the example shown is constructed as a Kepler system from the two collecting lenses (14, 15).
  • the lens (15) is in the direction of Arrow (l ⁇ ) can be moved.
  • a focus is formed in the beam path, is arranged in which a mode diaphragm (17) which is designed as an iris diaphragm 'and is also referred to as a spatial filter.
  • This diaphragm (17) serves to achieve a sharply defined boundary of the radiation field, the diameter of which is adjusted by moving the lens (15).
  • Another mirror (18) deflects the laser radiation out of the housing (12).
  • This mirror can be rotated about two mutually perpendicular axes with the help of only one actuating element.
  • the example of such a swivel mechanism is the subject of German utility model application G 85 35 100.8.
  • a filter (19) can also be swiveled in and out, as indicated by the double arrow. If the radiation is to be carried out with radiation from the laser (1), the filter (19) is pivoted out and the entire intensity of the radiation reaches the radiation field via the mirror (18). If the radiation is to be carried out with the radiation from the laser (5), the laser (1) remains switched on and the filter (19) is pivoted in. Only a portion of the radiation at 633 nm is transmitted through this filter. This enables precise positioning of the radiation field without triggering a therapeutic effect. Such a positioning option is important because the laser (5) emits in the near infrared and its radiation is therefore not visible. The observation field is thus illuminated by the visible radiation from the laser (1) with a sharp edge and it is precisely within this illuminated field that the therapeutically effective radiation from the laser (5) is uniformly distributed.
  • Fig. 2 shows an embodiment of the device according to the invention.
  • This tube can be pivoted in the direction of the double arrow (20). It has an operating ring (21) for axially displacing the lens (15), that is to say for adjusting the size of the radiation field, and an operating ring (22) for pivoting the mirror (18). All other components shown in Fig. 1 are housed in a housing (23) which has a control panel (24).
  • the display (10) of the radiation intensity is arranged in this field, furthermore control elements for pivoting the filter (19) in and out, for preselecting the duration of the radiation and for actuating the lasers (1) and (5).
  • the housing (23) is mounted on a table (24) which is arranged on a column (25). This column is mobile.
  • the therapeutic laser radiation can be directed in a simple manner onto a field to be treated in a standing, sitting or lying patient.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Laser Surgery Devices (AREA)

Abstract

Le dispositif ci-décrit comporte un laser HeNe (1) qui émet sur une longueur d'onde de 633 nm, et un second laser (5) émettant dans la plage du proche infra-rouge. Ce second laser (5) fonctionne en régime continu et émet un rayonnement dans la plage de longueur d'onde 800-870 nm, de préférence sur une longueur d'onde de 840 nm. Un système optique (14, 15) sert à élargir les faisceaux des deux lasers (1, 5) qui partagent la même trajectoire. Ce système (14, 15) permet de régler en continu la grandeur du champ d'irradiation jusqu'à un diamètre maximal de l'ordre de 30 nm. Pour le coudage du faisceau entre les lasers (1, 5) et l'ouverture de sortie de faisceau du dispositif, est prévu un système de miroirs (11, 18) comportant un miroir de sortie rotatif autour de deux axes pour positionner le champ d'irridiation.The device described above comprises a HeNe laser (1) which emits on a wavelength of 633 nm, and a second laser (5) emitting in the near infrared range. This second laser (5) operates continuously and emits radiation in the wavelength range 800-870 nm, preferably over a wavelength of 840 nm. An optical system (14, 15) serves to widen the beams of two lasers (1, 5) which share the same path. This system (14, 15) makes it possible to continuously adjust the size of the irradiation field up to a maximum diameter of the order of 30 nm. For the bending of the beam between the lasers (1, 5) and the beam exit aperture of the device, a system of mirrors (11, 18) is provided comprising an exit mirror rotating around two axes to position the field d. irridiation.

Description

Beschreibung:Description:
Vorrichtung zur therapeutischen Bestrahlung von organischem Gewebe mit LaserstrahlungDevice for the therapeutic irradiation of organic tissue with laser radiation
Die vorliegende Erfindung betrifft eine Vorrichtung zur therapeutischen Bestrahlung von organischem Gewebe nach dem Oberbegriff des Anspruchs 1.The present invention relates to a device for the therapeutic irradiation of organic tissue according to the preamble of claim 1.
Solche Vorrichtungen sind als sogenannte Mid- oder Soft-Laser bekannt geworden. Sie werden zur Behandlung auf verschiedenen Gebieten, beispielsweise in der Rheumatologie, der Dermatologie, der Neurclogie oder in der Dental-Medizin eingesetzt. Die Behandlung mit Laserstrahlen ist schmerzlos und verursacht weder Erwärmung noch eine mαkrochemische Veränderung des Gewebes. Die Laserstrahlung wirkt stimulierend auf die Zellaktivitäten und aktiviert damit körpereigene Heilkräfte; sie wirkt vor allem antiphlogistisch, antiöde atös und schmerzstillend und ist dabei frei von irgendwelchen Nebenwirkungen.Such devices have become known as so-called mid or soft lasers. They are used for treatment in various fields, for example in rheumatology, dermatology, neurclogy or in dental medicine. Treatment with laser beams is painless and does not cause warming or a micro-chemical change in the tissue. The laser radiation has a stimulating effect on cell activities and thus activates the body's own healing powers; Above all, it has an anti-inflammatory, anti-dreary and pain-relieving effect and is free of any side effects.
Es sind Mid-Laser bekannt, die einen HeNe-Laser enthalten, der Strahlung einer Wellenlänge von 633 nm emittiert. Diese Strahlung wird über flexible Glasfasern dem Ort der Bestrahlung zugeführt. Dabei wird die ursprünglich polarisierte Laserstrahlung depolarisiert. Solche Laser werden vorzugsweise zur Wundbehandlung eingesetzt.Mid lasers are known which contain a HeNe laser which emits radiation with a wavelength of 633 nm. This radiation is fed to the location of the radiation via flexible glass fibers. The originally polarized laser radiation is depolarized. Such lasers are preferably used for wound treatment.
Weiterhin sind Mid-Laser bekannt, die zusätzlich einen zweiten Laser enthalten, der Strahlung einer Wellenlänge von 904 nm emittiert. Hier erfolgt die Strahlzuführung zum Ort der Bestrahlung direkt, d.h. ohne Zwischenschaltung optischer Elemente. Dadurch ist eine solche Vorrichtung recht schwerfällig zu handhaben.Mid lasers are also known which additionally contain a second laser which emits radiation with a wavelength of 904 nm. Here the beam is fed directly to the radiation site, i.e. without the interposition of optical elements. This makes such a device very difficult to handle.
Bei diesen bekannten Mid-Lasern wird der Laserstrahl in Form eines Abtastrasters über das Bestrahlungsfeld geführt. Dies bringt den Nachteil mit sich, daß die Leistungsdichte über dieses Feld ungleich¬ mäßig verteilt ist, da sie in und nahe den Umkehrpunkten höher ist als in den dazwischenliegenden Bereichen. Bei den bekannten Mid-Lasern mit einem, bei 904 nm emittierenden Laser, wird dieser gepulst, wobei die Pulsfrequenz einstellbar ist und im oberen Bereich bis ca. 5 kHz reicht. Die verwendeten Halbleiterdioden -geben dabei im zeitlichen Mittelwert nur eine geringe Leistung ab, die im allgemeinen bei etwa 5 mW und darunter liegt.In these known mid-lasers, the laser beam is guided over the radiation field in the form of a scanning grid. This has the disadvantage that the power density is unevenly distributed over this field, since it is higher in and near the reversal points than in the areas in between. In the known mid-lasers with a laser emitting at 904 nm, this is pulsed, the pulse frequency being adjustable and reaching up to about 5 kHz in the upper range. The semiconductor diodes used in this case only emit a low power on average over time, which is generally about 5 mW and below.
Es ist die Aufgabe der vorliegenden Erfindung eine Vorrichtung zur therapeutischen Bestrahlung von organischem Gewebe nach dem Oberbegriff des Anspruchs 1 so auszugestalten, daß bei geringem Aufwand eine, gegenüber bekannten Vorrichtungen verbesserte therapeutische Wirksamkeit erreicht wird.It is the object of the present invention to design a device for the therapeutic irradiation of organic tissue according to the preamble of claim 1 in such a way that, with little effort, an improved therapeutic effectiveness compared to known devices is achieved.
Diese Aufgabe wird erfindungsgerrπß durch eine Vorrichtung gelöst, welche die im Kennzeichen des Anspruchs 1 angeführten Merkmale aufweist.This object is achieved according to the invention by a device which has the features stated in the characterizing part of claim 1.
Bei der Vorrichtung nach der Erfindung emittiert der im nahen Infrarotbereich arbeitende Laser Strahlung aus dem Wellenlängenbereich 800-870 nm, vorzugsweise bei 840 nm. Diese Strahlung wird im Dauer¬ strahlbetrieb abgegeben und durch ein optisches System auf einen gewünschten Durchmesser am Ort der Bestrahlung aufgeweitet.In the device according to the invention, the laser working in the near infrared range emits radiation from the wavelength range 800-870 nm, preferably at 840 nm. This radiation is emitted in continuous beam mode and expanded by an optical system to a desired diameter at the location of the radiation.
Damit ist einmal erreicht, daß ein Bestrahlungsfeld einstellbarer Größe mit gleichmäßig verteilter Leistungsdichte beaufschlagt wird, wobei der Laser, der vorteilhaft als GaAs-Halbleiterdiode ausgebildet ist im zeitlichen Mittelwert eine Leistung von etwa 100 mW abgibt.This once achieved that an irradiation field of adjustable size is subjected to a uniformly distributed power density, the laser, which is advantageously designed as a GaAs semiconductor diode, emitting an average power of approximately 100 mW.
Durch die Wahl der Wellenlänge und die kontinuierliche Einstrahlung der Laserstrahlung wird eine signifikante Verbesserung der therapeutischen Wirkung erreicht. Beim Zellstoffwechsel organischer Zellen entsteht einA significant improvement in the therapeutic effect is achieved through the choice of the wavelength and the continuous irradiation of the laser radiation. When cell metabolism occurs in organic cells
Enzym (aus der Gruppe der Flavoproteide) , dessen AbsorptionsfähigkeitEnzyme (from the group of flavoproteids), its absorption capacity
-3 kurzzeitig für eine Dauer <10 s bei etwa 840 nm am höchsten ist.-3 is briefly highest for a period of <10 s at about 840 nm.
Dieses Enzym absorbiert aus der auftreffenden Laserstrahlung Photonen und diese bewirken u.a. einen Ladungsträger-Austausch. Dabei werden dieThis enzyme absorbs photons from the incident laser radiation and these cause, among other things. a load carrier exchange. The
Zeil-Membranen polarisiert und damit der Zellstoffwechsel stimuliert.Zeil membranes polarize and thus stimulate cell metabolism.
Damit werden körpereigene Heilkräfte aktiviert. Die kontinuierliche Einstrahlung der Laserstrahlung bewirkt, daß an jeder Stelle des Bestrahlungsfeldes eine bestimmte Photonenzahl pro Flächen- und Zeiteinheit zur Verfügung steht. Damit stehen bei jedem Auftreten des erwähnten kurzzeitig existenten Absorptionszustandes des Enzyms eine ausreichende Anzahl von Photonen in dem für die Absorption optimalen Wellenlängenbereich zur Verfügung, so daß eine Stimulation des Zellstoffwechsels erfolgen kann. Da die Leistungsdichte der Bestrahlung über das bestrahlte Feld gleichmäßig verteilt ist, treten die stimulierenden Effekte gleichmäßig verteilt über dieses Feld auf.This activates the body's own healing powers. The continuous irradiation of the laser radiation has the effect that a certain number of photons per unit area and time is available at every point in the radiation field. With each occurrence of the abovementioned briefly existing absorption state of the enzyme, a sufficient number of photons are available in the wavelength range optimal for absorption, so that stimulation of the cell metabolism can take place. Since the power density of the radiation is evenly distributed over the irradiated field, the stimulating effects occur evenly distributed over this field.
Bei der Vorrichtung nach der Erfindung erfolgt die Zuführung der Laserstrahlung zum Bestrahlungsfeld über Spiegel. Damit ist gewähr¬ leistet, daß die vom HeNe-Laser emittierte polarisierte Strahlung auf ihrem Weg zum Bestrahlungsfeld nicht depolarisiert wird, d.h., daß sie dort tatsächlich als polarisierte Strahlung auftrifft. Es hat sich gezeigt, daß dadurch der Wundverschluß beschleunigt wird, so daß' die Vorrichtung in hohem Maße stimulierend auf das Ephitelgewebe einwirkt.In the device according to the invention, the laser radiation is supplied to the radiation field via mirrors. This ensures that the polarized radiation emitted by the HeNe laser is not depolarized on its way to the radiation field, ie that it actually strikes it as polarized radiation. It has been found that by the closure of the wound is accelerated, so that 'acts, the apparatus highly stimulating to the Ephitelgewebe.
Die Verwendung von Spiegeln erlaubt es auch die Strahlzuführung sehr flexibel zu gestalten, so daß es einfach ist das Bestrahlungsfeld auf dem zu behandelnden Körper zu positionieren.The use of mirrors also allows the beam delivery to be designed very flexibly, so that it is easy to position the radiation field on the body to be treated.
Die Vorrichtung nach der Erfindung enthält besonders vorteilhaft eine Anordnung zur internen Leistungsmessung. Diese Anordnung zeigt die Leistung der emittierten Laserstrahlung kontinuierlich an und ermöglicht damit eine genaue Dosierung der auf das Bestrahlungsfeld auftreffenden Laserstrahlung.The device according to the invention particularly advantageously contains an arrangement for internal power measurement. This arrangement continuously displays the power of the emitted laser radiation and thus enables precise metering of the laser radiation striking the radiation field.
Bei der Therapie mittels des HeNe-Lasers ist es notwendig dessen Intensität zu steuern. Dazu ist bei der Vorrichtung nach der Erfindung im Strahlengang vorteilhaft eine LCD-Platte angeordnet. Der Grad der Ausrichtung der LCD-Kristalle und damit die Absorption der polarisierten Laserstrahlung läßt sich in besonders einfacher Weise mittels der an die LCD-Platte angelegten Spannung steuern. Die Erfindung wird im folgenden anhand eines in den Fig. 1 und 2 der beigefügten Zeichnungen dargestellten Ausführungsbeispiels näher erläutert. Dabei zeigt:With therapy using the HeNe laser, it is necessary to control its intensity. For this purpose, an LCD panel is advantageously arranged in the beam path in the device according to the invention. The degree of alignment of the LCD crystals and thus the absorption of the polarized laser radiation can be controlled in a particularly simple manner by means of the voltage applied to the LCD plate. The invention is explained below with reference to an embodiment shown in FIGS. 1 and 2 of the accompanying drawings. It shows:
Fig. 1 den optischen Strahlengang in schematischer Darstellung;Figure 1 shows the optical beam path in a schematic representation.
Fig. 2 ein perspektivische Ansicht der Vorrichtung.Fig. 2 is a perspective view of the device.
In Fig. 1 ist mit (1) ein bei ό33 nm emittierender HeNe-Laser bezeichnet. Die von diesem emittierte polarisierte Strahlung tritt durch eine LCD-Platte (2). Diese Platte besteht-aus einer dünnen Flüssig¬ kristall-Schicht, die zwischen zwei, mit durchsichtigen Elektroden versehenen Glasplatten angeordnet ist. Zwischen diesen Elektroden wird über eine Steuer-Anordnung (3) eine regelbare Spannung angelegt. Die Größe dieser Spannung regelt die Intensität der durch die Platte (2) tretenden Strahlung.In Fig. 1, (1) denotes a HeNe laser emitting at ό33 nm. The polarized radiation emitted by this passes through an LCD panel (2). This plate consists of a thin liquid crystal layer which is arranged between two glass plates provided with transparent electrodes. A controllable voltage is applied between these electrodes via a control arrangement (3). The magnitude of this voltage regulates the intensity of the radiation passing through the plate (2).
Hinter der LCD-Platte (2) ist ein Teilerspiegel (4) angeordnet, über den die von der Laserdiode (5) emittierte Strahlung in den Strahlengang gelangt. Die Laserdiode (5) ist als GaAs-Diode ausgebildet, die bei 840 nm emittiert und die im Dauerstrahl- (Dauerstrich-) Betrieb arbeitet. Ein Kondensor-System (6) dient zur Erzeugung eines Parallelstrahlen- ganges. Hinter dem Spiegel (4) verläuft die von den Lasern (1 und 2) emittierte Strahlung koaxial über denselben Strahlungsweg und wird von denselben Bauelementen beeinflußt. In diesem Strahlengang ist ein teilreflektierender Spiegel (7) angeordnet, der einen kleinen Prozentsatz der auftreffenden Strahlung auf einen Detektor (8) lenkt. Diesem ist ein Verstärker (9) und ein Anzeigeinstrument (10) nachgeordnet. Dieses zeigt die Leistung im Laserstrahlengang an.A splitter mirror (4) is arranged behind the LCD plate (2), via which the radiation emitted by the laser diode (5) enters the beam path. The laser diode (5) is designed as a GaAs diode, which emits at 840 nm and which operates in continuous wave (continuous wave) mode. A condenser system (6) is used to generate a parallel beam path. Behind the mirror (4), the radiation emitted by the lasers (1 and 2) runs coaxially over the same radiation path and is influenced by the same components. A partially reflecting mirror (7) is arranged in this beam path and directs a small percentage of the incident radiation onto a detector (8). This is followed by an amplifier (9) and a display instrument (10). This shows the power in the laser beam path.
Der Laserstrahlengang wird über einen Spiegel (11) umgelenkt, der in einem rohrförmigen Gehäuse (12) angeordnet ist, das um eine, mit der optischen Achse (13) zusammenfallende Achse drehbar ist. Im Gehäuse (12) ist ein optisches System zur Strahlaufweitung angeordnet, das im dargestellten Beispiel als Kepler-System aus den beiden sammelnden Linsen (14, 15) aufgebaut ist. Die Linse (15) ist in Richtung des Pfeiles (lό) verschiebbar. Zwischen den Linsen (14) und (15) entsteht ein Fokus im Strahlengang, in dem eine Modenblende (17) angeordnet ist, die als Irisblende 'ausgebildet ist und auch als Raumfilter bezeichnet wird. Diese Blende (17) dient dazu eine randscharfe Begrenzung des - Bestrahlungsfeldes zu erreichen, dessen Durchmesser durch Verschieben der Linse (15) eingestellt wird.The laser beam path is deflected via a mirror (11) which is arranged in a tubular housing (12) which can be rotated about an axis coinciding with the optical axis (13). An optical system for beam expansion is arranged in the housing (12), which in the example shown is constructed as a Kepler system from the two collecting lenses (14, 15). The lens (15) is in the direction of Arrow (lό) can be moved. Between the lenses (14) and (15), a focus is formed in the beam path, is arranged in which a mode diaphragm (17) which is designed as an iris diaphragm 'and is also referred to as a spatial filter. This diaphragm (17) serves to achieve a sharply defined boundary of the radiation field, the diameter of which is adjusted by moving the lens (15).
Ein weiterer Spiegel (18) lenkt die Laserstrahlung aus dem Gehäuse (12) aus. Dieser Spiegel ist um zwei zueinander senkrechte Achsen drehbar und zwar mit Hilfe nur eines Betätigungselementes. Die beispielsweise Ausbildung eines solchen Schwenkmechanismus ist Gegenstand der deutschen Gebrauchsmusteranmeldung G 85 35 100.8.Another mirror (18) deflects the laser radiation out of the housing (12). This mirror can be rotated about two mutually perpendicular axes with the help of only one actuating element. The example of such a swivel mechanism is the subject of German utility model application G 85 35 100.8.
Im Strahlengang (13) ist weiterhin ein Filter (19) ein- und ausschwenk¬ bar angeordnet, wie dies durch den Doppelpfeil angedeutet ist. Soll die Bestrahlung mit Strahlung des Lasers (1) durchgeführt werden, so ist das Filter (19) ausgeschwenkt und die gesamte Intensität der Strahlung gelangt über den Spiegel (18) zum Bestrahlungsfeld. Soll die Bestrahlung mit der Strahlung des Lasers (5) durchgeführt werden, so bleibt der Laser (1) eingeschaltet und das Filter (19) wird eingeschwenkt. Durch dieses Filter wird nur ein Teil der Strahlung bei 633 nm durchgelassen. Diese ermöglicht ein genaues Positionieren des Bestrahlungsfeldes ohne eine therapeutische Wirkung auszulösen. Eine solche Möglichkeit der Positionierung ist wichtig, da der Laser (5) im nahen Infrarot emittiert und seine Strahlung deshalb nicht sichtbar ist. Das Beobachtungsfeld wird also von der sichtbaren Strahlung des Lasers (1) randscharf beleuchtet und genau innerhalb dieses beleuchteten Feldes trifft gleichmäßig verteilt die therapeutisch wirksame Strahlung des Lasers (5) kontinuierlich auf.In the beam path (13), a filter (19) can also be swiveled in and out, as indicated by the double arrow. If the radiation is to be carried out with radiation from the laser (1), the filter (19) is pivoted out and the entire intensity of the radiation reaches the radiation field via the mirror (18). If the radiation is to be carried out with the radiation from the laser (5), the laser (1) remains switched on and the filter (19) is pivoted in. Only a portion of the radiation at 633 nm is transmitted through this filter. This enables precise positioning of the radiation field without triggering a therapeutic effect. Such a positioning option is important because the laser (5) emits in the near infrared and its radiation is therefore not visible. The observation field is thus illuminated by the visible radiation from the laser (1) with a sharp edge and it is precisely within this illuminated field that the therapeutically effective radiation from the laser (5) is uniformly distributed.
Die Zeitdauer des therapeutischen Einsatzes wird durch eine Zeitschal¬ tung gesteuert, die direkt auf den Bewegungsmechanismus für das Filter (19) und auf den Laser (5) einwirkt und die beim Einschalten des Lasers (5) das Filter (19) einschwenkt und umgekehrt. Fig. 2 zeigt ein Ausführungsbeispiel der Vorrichtung nach der Erfindung. Man erkennt das rohrförmige Gehäuse (12), das die aus Fig. 1 ersicht¬ lichen Bauelemente enthält. Dieses Rohr ist in Richtung des Doppelpfeils (20) schwenkbar. Es weist einen Bedienungsring (21) zur Axialverschie¬ bung der Linse (15), d.h. also zur Einstellung der Größe des Bestrahlungsfeldes und einen Bedienungsring (22) zur Verschwenkung des Spiegels (18) auf. Alle übrigen aus Fig. 1 ersichtlichen Bauelemente sind in einem Gehäuse (23) untergebracht, das ein Bedienfeld (24) aufweist. In diesem Feld ist die Anzeige (10) der Strahlungsintensität angeordnet, ferner Bedienelemente zum Ein- und Ausschwenken des Filters (19), zur Vorwahl der Bestrahlungsdauer und zur Betätigung der Laser (1) und (5).The duration of the therapeutic use is controlled by a timer which acts directly on the movement mechanism for the filter (19) and on the laser (5) and which pivots in the filter (19) when the laser (5) is switched on and vice versa. Fig. 2 shows an embodiment of the device according to the invention. One recognizes the tubular housing (12) which contains the components shown in FIG. 1. This tube can be pivoted in the direction of the double arrow (20). It has an operating ring (21) for axially displacing the lens (15), that is to say for adjusting the size of the radiation field, and an operating ring (22) for pivoting the mirror (18). All other components shown in Fig. 1 are housed in a housing (23) which has a control panel (24). The display (10) of the radiation intensity is arranged in this field, furthermore control elements for pivoting the filter (19) in and out, for preselecting the duration of the radiation and for actuating the lasers (1) and (5).
Das Gehäuse (23) ist auf einem Tisch (24) gelagert, der auf einer Säule (25) angeordnet ist. Diese Säule ist fahrbar.The housing (23) is mounted on a table (24) which is arranged on a column (25). This column is mobile.
Durch Positionieren der Säule (25) und durch Verschwenken des Rohres (12) sowie des Austrittsspiegels (18) läßt sich in einfacher Weise die therapeutische Laserstrahlung auf ein zu behandelndes Feld eines stehenden, sitzenden oder liegenden Patienten richten.By positioning the column (25) and pivoting the tube (12) and the exit mirror (18), the therapeutic laser radiation can be directed in a simple manner onto a field to be treated in a standing, sitting or lying patient.
Es kann vorteilhaft sein die Säule (25) so auszubilden, daß der Tisch (24) in der Höhe verstellbar ist. It can be advantageous to design the column (25) so that the height of the table (24) can be adjusted.

Claims

Patentansprüche: Claims:
1. Vorrichtung zur therapeutischen Bestrahlung von organischem Gewebe mit Laserstrahlung, enthaltend einen HeNe-Laser und einen im nahen Infrarotbereich arbeitenden zweiten Laser, sowie Mittel zur Zuführung der Laserstrahlung zum Ort der Bestrahlung, dadurch gekennzeichnet, daß der zweite Laser (5) im Dauerstrahl-Betrieb arbeitet und Strahlung aus dem Wellenlängenbereich 800-870 nm emittiert, daß ein optisches System (14, 15) zur Aufweitung des Laserstrahls auf einen gewünschten Durchmesser am Ort der Bestrahlung vorgesehen ist, und daß ι:ur Strahlumlenkung zwischen Laser (1, 5) und der Strahlaustrittsöffnung der Vorrichtung Spiegel (11, 18) dienen.1. Device for the therapeutic irradiation of organic tissue with laser radiation, comprising a HeNe laser and a second laser working in the near infrared range, and means for supplying the laser radiation to the site of the radiation, characterized in that the second laser (5) in the continuous beam Operation works and radiation from the wavelength range 800-870 nm is emitted, that an optical system (14, 15) is provided for expanding the laser beam to a desired diameter at the site of the irradiation, and that ι: ur beam deflection between the laser (1, 5) and the beam outlet opening of the device mirrors (11, 18) are used.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß der zweite Laser (5) Strahlung einer Wellenlänge von 840 nm emittiert.2. Device according to claim 1, characterized in that the second laser (5) emits radiation of a wavelength of 840 nm.
3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, daß der zweite Laser (5) als Halbleiterdiode ausgebildet ist.3. Apparatus according to claim 2, characterized in that the second laser (5) is designed as a semiconductor diode.
4. Vorrichtung nach Anspruch 1 und 2, dadurch gekennzeichnet, daß eine Anordnung (7, 8, 9, 10) zur internen Leistungsmessung vorgesehen ist.4. Apparatus according to claim 1 and 2, characterized in that an arrangement (7, 8, 9, 10) is provided for internal power measurement.
5. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß im Strahlengang des HeNe-Lasers (1) eine, der Intensitätssteuerung dienende LCD-Platte (2) angeordnet ist. 5. The device according to claim 1, characterized in that in the beam path of the HeNe laser (1), an intensity control LCD panel (2) is arranged.
EP87901050A 1986-02-03 1987-02-03 Device for therapeutical irradiation of organic tissue by laser radiation Withdrawn EP0257052A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19863603156 DE3603156A1 (en) 1986-02-03 1986-02-03 DEVICE FOR THERAPEUTIC RADIATION OF ORGANIC TISSUE WITH LASER RADIATION
DE3603156 1986-02-03
DE19873731841 DE3731841A1 (en) 1986-02-03 1987-09-22 Irradiation unit for improvement of the immune system
DE19873734852 DE3734852A1 (en) 1986-02-03 1987-10-14 Irradiation unit for forming (endogenous) cancer-inhibiting matter

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EP (1) EP0257052A1 (en)
JP (1) JPS63503204A (en)
DE (3) DE3603156A1 (en)
WO (1) WO1987004632A1 (en)

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US4836203A (en) 1989-06-06
JPS63503204A (en) 1988-11-24
DE3734852A1 (en) 1989-04-27
WO1987004632A1 (en) 1987-08-13
DE3603156A1 (en) 1987-08-06
DE3731841A1 (en) 1989-03-30

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