EP0245945A3 - Automated nucleic acid extractor - Google Patents
Automated nucleic acid extractor Download PDFInfo
- Publication number
- EP0245945A3 EP0245945A3 EP87303040A EP87303040A EP0245945A3 EP 0245945 A3 EP0245945 A3 EP 0245945A3 EP 87303040 A EP87303040 A EP 87303040A EP 87303040 A EP87303040 A EP 87303040A EP 0245945 A3 EP0245945 A3 EP 0245945A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- nucleic acid
- automated nucleic
- acid extractor
- extractor
- automated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00286—Reactor vessels with top and bottom openings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00331—Details of the reactor vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00389—Feeding through valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00488—Means for mixing reactants or products in the reaction vessels by rotation of the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00695—Synthesis control routines, e.g. using computer programs
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Cell Biology (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85086986A | 1986-04-11 | 1986-04-11 | |
US850869 | 1986-04-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0245945A2 EP0245945A2 (en) | 1987-11-19 |
EP0245945A3 true EP0245945A3 (en) | 1989-07-26 |
EP0245945B1 EP0245945B1 (en) | 1993-11-10 |
Family
ID=25309324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19870303040 Expired - Lifetime EP0245945B1 (en) | 1986-04-11 | 1987-04-08 | Automated nucleic acid extractor |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0245945B1 (en) |
JP (1) | JPH0815438B2 (en) |
DE (1) | DE3788082T2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8801098D0 (en) * | 1988-03-24 | 1988-03-24 | Pharmacia Ab | APPARATUS AND METHOD FOR AUTOMATIC EXTRACTION OF EXTRA-CHROMOSOMAL DNA FROM A CELL SUSPENSION IN A CONTAINER |
EP0340609A3 (en) * | 1988-05-06 | 1991-07-31 | F. Hoffmann-La Roche Ag | Device for the isolation of nucleic acids |
US5334499A (en) * | 1989-04-17 | 1994-08-02 | Eastman Kodak Company | Methods of extracting, amplifying and detecting a nucleic acid from whole blood or PBMC fraction |
WO1990015148A1 (en) * | 1989-06-02 | 1990-12-13 | Mathias Uhlen | Apparatus and method for automated purification of extra-chromosomal dna from a cell suspension using a reaction device |
US4997932A (en) * | 1989-11-13 | 1991-03-05 | Boehringer Mannheim Corporation | Method and kit for purifying nucleic acids |
GB9025516D0 (en) * | 1990-11-23 | 1991-01-09 | Cambridge Technology & Science | Assay |
FR2678950B1 (en) * | 1991-07-09 | 1993-11-05 | Bertin Et Cie | CARTRIDGE, DEVICE AND METHOD FOR EXTRACTING NUCLEIC ACIDS SUCH AS DNA FROM A SAMPLE OF BLOOD OR TISSUE CELLS. |
FR2712511B1 (en) * | 1993-11-16 | 1996-02-09 | Bertin & Cie | Cartridge for the preparation of purified nucleic acids. |
DE4420732A1 (en) * | 1994-06-15 | 1995-12-21 | Boehringer Mannheim Gmbh | Device for the treatment of nucleic acids from a sample |
US6146854A (en) * | 1995-08-31 | 2000-11-14 | Sequenom, Inc. | Filtration processes, kits and devices for isolating plasmids |
DE19746874A1 (en) * | 1997-10-23 | 1999-04-29 | Qiagen Gmbh | Isolation of nucleic acids |
GB2347141B (en) * | 1998-09-26 | 2002-01-16 | Brendan James Hamill | Combinatorial synthesiser |
FR2838066B1 (en) * | 2002-04-09 | 2004-06-25 | Genesystems | METHOD AND AUTOMATE FOR EXTRACTING NUCLEIC ACIDS FROM A COMPLEX MIXTURE |
WO2004094634A1 (en) * | 2003-04-22 | 2004-11-04 | Arkray Inc. | Method of isolating nucleic acid and, for nucleic acid isolation, kit and apparatus |
WO2012115926A2 (en) * | 2011-02-21 | 2012-08-30 | Rheonix, Inc. | Microfluidic device-based nucleic acid purification method |
ES2933132T3 (en) | 2017-05-05 | 2023-02-01 | Biomerieux Sa | Procedure to detect a cellular immune response |
EP3697924A1 (en) | 2017-10-16 | 2020-08-26 | Enterome | New tools for assessing fimh blockers therapeutic efficiency |
CN113195701A (en) * | 2019-01-11 | 2021-07-30 | 盖立复诊断解决方案公司 | Device for disrupting cells |
EP4206324A1 (en) * | 2022-01-04 | 2023-07-05 | Phynexus, Inc. | Purification of macromolecules |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3389133A (en) * | 1966-08-10 | 1968-06-18 | Schwarz Biores Inc | Process for isolating and purifying soluble ribonucleic acid |
DE1808800A1 (en) * | 1967-11-16 | 1969-08-28 | Brown James Boyer | Device for mixing and separating liquids |
GB2018927A (en) * | 1978-04-14 | 1979-10-24 | Piper E J | Improvements in or relating to connector |
EP0215533A2 (en) * | 1985-01-18 | 1987-03-25 | Applied Biosystems, Inc. | A method of extracting nucleic acids from cells |
-
1987
- 1987-04-08 DE DE19873788082 patent/DE3788082T2/en not_active Expired - Fee Related
- 1987-04-08 EP EP19870303040 patent/EP0245945B1/en not_active Expired - Lifetime
- 1987-04-10 JP JP62088585A patent/JPH0815438B2/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3389133A (en) * | 1966-08-10 | 1968-06-18 | Schwarz Biores Inc | Process for isolating and purifying soluble ribonucleic acid |
DE1808800A1 (en) * | 1967-11-16 | 1969-08-28 | Brown James Boyer | Device for mixing and separating liquids |
GB2018927A (en) * | 1978-04-14 | 1979-10-24 | Piper E J | Improvements in or relating to connector |
EP0215533A2 (en) * | 1985-01-18 | 1987-03-25 | Applied Biosystems, Inc. | A method of extracting nucleic acids from cells |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, vol. 67, no. 6, 7th August 1967, abstract no. 28932n, N.M. KREDICH et al.: 'An inexpensive Luer-fitting chromatographic column', & Anal. Biochem., vol. 19, no. 1, 1967, pages 190 - 192 * |
METHODS IN ENZYMOLOGY, vol. 152, 1987, Academic Press Inc., San Diego, Cafifornia, US, pages 33 - 39 and pages 180 - 183 * |
Also Published As
Publication number | Publication date |
---|---|
EP0245945A2 (en) | 1987-11-19 |
DE3788082D1 (en) | 1993-12-16 |
DE3788082T2 (en) | 1994-06-09 |
EP0245945B1 (en) | 1993-11-10 |
JPH0815438B2 (en) | 1996-02-21 |
JPS6322194A (en) | 1988-01-29 |
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