EP0240550A4 - Lungen-oberflachenaktive proteine. - Google Patents

Lungen-oberflachenaktive proteine.

Info

Publication number
EP0240550A4
EP0240550A4 EP19860906180 EP86906180A EP0240550A4 EP 0240550 A4 EP0240550 A4 EP 0240550A4 EP 19860906180 EP19860906180 EP 19860906180 EP 86906180 A EP86906180 A EP 86906180A EP 0240550 A4 EP0240550 A4 EP 0240550A4
Authority
EP
European Patent Office
Prior art keywords
pulmonary surfactant
surfactant proteins
proteins
pulmonary
surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19860906180
Other languages
English (en)
French (fr)
Other versions
EP0240550A1 (de
Inventor
H William Taeusch Jr
Kenneth A Jacobs
D Randall Steinbrink
Joanna Floros
Davis S Phelps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Genetics Institute LLC
Original Assignee
Brigham and Womens Hospital Inc
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc, Genetics Institute LLC filed Critical Brigham and Womens Hospital Inc
Publication of EP0240550A1 publication Critical patent/EP0240550A1/de
Publication of EP0240550A4 publication Critical patent/EP0240550A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19860906180 1985-09-26 1986-09-26 Lungen-oberflachenaktive proteine. Withdrawn EP0240550A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78113085A 1985-09-26 1985-09-26
US781130 1985-09-26
US89718386A 1986-08-15 1986-08-15
US897183 1986-08-15

Publications (2)

Publication Number Publication Date
EP0240550A1 EP0240550A1 (de) 1987-10-14
EP0240550A4 true EP0240550A4 (de) 1989-09-19

Family

ID=27119809

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860906180 Withdrawn EP0240550A4 (de) 1985-09-26 1986-09-26 Lungen-oberflachenaktive proteine.

Country Status (2)

Country Link
EP (1) EP0240550A4 (de)
WO (1) WO1987002037A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
EP0273916A4 (de) * 1986-05-06 1989-11-30 Childrens Hosp Medical Center Lungenhydrophobes, an ein oberflächenaktives mittel assoziiertes protein von 6000 dalton molekulargewicht sowie multimere davon.
WO1988003170A1 (en) * 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト,ジエフリー エイ. 肺胞疎水性界面活性物質関連タンパク質
EP0313224A1 (de) * 1987-09-28 1989-04-26 Children's Hospital Medical Center Menschliche Zellinien von Epithellungenadenokarzinom, menschliche Proteine und Verfahren
US5238920A (en) * 1989-08-22 1993-08-24 Abbott Laboratories Pulmonary surfactant protein fragments
EP0458167B1 (de) * 1990-05-21 1997-04-23 Abbott Laboratories Fettsäure-Oberflächenaktives-Lungenprotein Konjate
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
US20060275274A1 (en) * 2003-03-26 2006-12-07 Daria Onichtchouk Use of saposin-related proteins for preventing and treating obesity, diabetes and/or metabolic syndrome
WO2009035395A1 (en) 2007-09-14 2009-03-19 Marcus Larsson A lung-surfactant product

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003408A1 (en) * 1984-12-11 1986-06-19 California Biotechnology Inc. Recombinant alveolar surfactant protein
WO1986004920A1 (en) * 1985-02-13 1986-08-28 Biotechnology Research Partners, Limited Human metallothionein-ii promoter in mammalian expression system
WO1987006588A1 (en) * 1986-04-30 1987-11-05 California Biotechnology Inc. Recombinant alveolar surfactant protein
EP0145005B1 (de) * 1983-12-08 1989-04-12 VEB Arzneimittelwerk Dresden Lungen-Surfactant, Verfahren zu seiner Herstellung und seine pharmazeutische Verwendung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
ES506955A0 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
US4615974A (en) * 1981-08-25 1986-10-07 Celltech Limited Yeast expression vectors
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US4605627A (en) * 1983-06-07 1986-08-12 The Regents Of The University Of California Plasmid vehicle for cloning in Agrobacterium tumefaciens
JP2551746B2 (ja) * 1983-07-19 1996-11-06 サントリー株式会社 改良プラスミドベクタ−およびその利用
US4579321A (en) * 1983-12-30 1986-04-01 U.S. Amada Ltd. Positioner of compact type for working position in sheet or plate machining

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0145005B1 (de) * 1983-12-08 1989-04-12 VEB Arzneimittelwerk Dresden Lungen-Surfactant, Verfahren zu seiner Herstellung und seine pharmazeutische Verwendung
WO1986003408A1 (en) * 1984-12-11 1986-06-19 California Biotechnology Inc. Recombinant alveolar surfactant protein
WO1986004920A1 (en) * 1985-02-13 1986-08-28 Biotechnology Research Partners, Limited Human metallothionein-ii promoter in mammalian expression system
WO1987006588A1 (en) * 1986-04-30 1987-11-05 California Biotechnology Inc. Recombinant alveolar surfactant protein

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 135, nr. 2, 13th March 1986, New York, Akio Takahashi et al.: "Proteolipid in Bovine Lung Surfactant; Its Role in Surfactant Fuction", Pages 527-532 *
CHEMICAL ABSTRACTS, vol. 105, no. 11, 15th September 1986, abs. 92339e, Columbus, Ohio, US: Joann Floros et al.: "Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein"; & J. Biol. Chem. 1986, vol. 261, no. 19, pages 9029-9033 *
NATURE, Vol. 317, 26th September 1985, London, GB; R. Tyler White et al.: "Isolation and characterization of the human pulmonary surfactant apoprotein gene", pages 361-363 *
PEDIATRIC RESEARCH, vol. 20, no.5, May 1986, Baltimore, US; Jeffrey A. Whitsett et al.: "Hydrophobic Surfctant-Associated Protein in whole Lung Surfctant and its Importance for Biophysical Activity in Lung Surfctant Extracts used for Replcement Therapy", Pages 460-467 *
See also references of WO8702037A1 *

Also Published As

Publication number Publication date
EP0240550A1 (de) 1987-10-14
WO1987002037A1 (en) 1987-04-09

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19871009

A4 Supplementary search report drawn up and despatched

Effective date: 19890919

17Q First examination report despatched

Effective date: 19910809

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930830

RIN1 Information on inventor provided before grant (corrected)

Inventor name: TAEUSCH, H., WILLIAM, JR.

Inventor name: PHELPS, DAVIS, S.

Inventor name: JACOBS, KENNETH, A.

Inventor name: FLOROS, JOANNA

Inventor name: STEINBRINK, D., RANDALL