EP0211645A3 - Apparatus and methods for use in the mass analysis of chemical samples - Google Patents

Apparatus and methods for use in the mass analysis of chemical samples Download PDF

Info

Publication number
EP0211645A3
EP0211645A3 EP86306004A EP86306004A EP0211645A3 EP 0211645 A3 EP0211645 A3 EP 0211645A3 EP 86306004 A EP86306004 A EP 86306004A EP 86306004 A EP86306004 A EP 86306004A EP 0211645 A3 EP0211645 A3 EP 0211645A3
Authority
EP
European Patent Office
Prior art keywords
methods
mass analysis
chemical samples
samples
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP86306004A
Other versions
EP0211645A2 (en
EP0211645B1 (en
Inventor
Richard M Caprioli
John S Cottrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kratos Analytical Ltd
Original Assignee
Spectros Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/767,819 external-priority patent/US4908512A/en
Priority claimed from US06/767,820 external-priority patent/US4820648A/en
Application filed by Spectros Ltd filed Critical Spectros Ltd
Publication of EP0211645A2 publication Critical patent/EP0211645A2/en
Publication of EP0211645A3 publication Critical patent/EP0211645A3/en
Application granted granted Critical
Publication of EP0211645B1 publication Critical patent/EP0211645B1/en
Expired legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404—Capillaries used for transferring samples or ions
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0436—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples using a membrane permeable to liquids
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H01J49/142—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers using a solid target which is not previously vapourised

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP19860306004 1985-08-21 1986-08-04 Apparatus and methods for use in the mass analysis of chemical samples Expired EP0211645B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/767,819 US4908512A (en) 1985-08-21 1985-08-21 Apparatus and methods of use in the mass analysis of chemical samples
US767819 1985-08-21
US767820 1985-08-21
US06/767,820 US4820648A (en) 1985-08-21 1985-08-21 Methods for use in the mass analysis of chemical samples

Publications (3)

Publication Number Publication Date
EP0211645A2 EP0211645A2 (en) 1987-02-25
EP0211645A3 true EP0211645A3 (en) 1987-10-28
EP0211645B1 EP0211645B1 (en) 1990-07-18

Family

ID=27117963

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860306004 Expired EP0211645B1 (en) 1985-08-21 1986-08-04 Apparatus and methods for use in the mass analysis of chemical samples

Country Status (3)

Country Link
EP (1) EP0211645B1 (en)
JP (1) JPS6285851A (en)
DE (1) DE3672710D1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791292A (en) * 1986-04-24 1988-12-13 The Dow Chemical Company Capillary membrane interface for a mass spectrometer
WO1990012416A1 (en) * 1989-03-30 1990-10-18 Gruppo Lepetit S.P.A. Multiple targets for precise mass measurement
US5078135A (en) * 1989-05-31 1992-01-07 Board Of Regents, The University Of Texas System Apparatus for in vivo analysis of biological compounds in blood or tissue by microdialysis and mass spectrometry
US6054709A (en) * 1997-12-05 2000-04-25 The University Of British Columbia Method and apparatus for determining the rates of reactions in liquids by mass spectrometry
US10060838B2 (en) 2015-04-09 2018-08-28 Ut-Battelle, Llc Capture probe
US9632066B2 (en) 2015-04-09 2017-04-25 Ut-Battelle, Llc Open port sampling interface

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1512509A (en) * 1966-12-28 1968-02-09 Csf Device for introducing liquids into a mass spectrometer with a view to subjecting them to continuous analysis
US4209696A (en) * 1977-09-21 1980-06-24 Fite Wade L Methods and apparatus for mass spectrometric analysis of constituents in liquids
GB2050686A (en) * 1979-05-25 1981-01-07 Hewlett Packard Co Apparatus for Analyzing Liquid Samples with a Mass Spectrometer
GB2091937A (en) * 1981-01-27 1982-08-04 Nat Res Dev Mass analysis sample ionisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS601550A (en) * 1983-06-17 1985-01-07 Jeol Ltd Liquid chromatograph mass spectrometer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1512509A (en) * 1966-12-28 1968-02-09 Csf Device for introducing liquids into a mass spectrometer with a view to subjecting them to continuous analysis
US4209696A (en) * 1977-09-21 1980-06-24 Fite Wade L Methods and apparatus for mass spectrometric analysis of constituents in liquids
GB2050686A (en) * 1979-05-25 1981-01-07 Hewlett Packard Co Apparatus for Analyzing Liquid Samples with a Mass Spectrometer
GB2091937A (en) * 1981-01-27 1982-08-04 Nat Res Dev Mass analysis sample ionisation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANALYTICAL CHEMISTRY, vol. 57, no. 6, May 1985, pages 1153-1155; J.S. BRODBELT et al.: "An exceedingly simple mass spectrometer interface with application to reaction monitoring and environmental analysis" *

Also Published As

Publication number Publication date
JPH0577265B2 (en) 1993-10-26
EP0211645A2 (en) 1987-02-25
DE3672710D1 (en) 1990-08-23
JPS6285851A (en) 1987-04-20
EP0211645B1 (en) 1990-07-18

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