EP0192794B1 - Récipient pour liquides pour appareils d'analyse - Google Patents

Récipient pour liquides pour appareils d'analyse Download PDF

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Publication number
EP0192794B1
EP0192794B1 EP19850102198 EP85102198A EP0192794B1 EP 0192794 B1 EP0192794 B1 EP 0192794B1 EP 19850102198 EP19850102198 EP 19850102198 EP 85102198 A EP85102198 A EP 85102198A EP 0192794 B1 EP0192794 B1 EP 0192794B1
Authority
EP
European Patent Office
Prior art keywords
vessel
layer
liquid
membrane
calibrating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP19850102198
Other languages
German (de)
English (en)
Other versions
EP0192794A1 (fr
Inventor
Takeshi 1-638 Daigo Ishida Danchi Kohno
Hiroaki 3-303 Rakusei Shinbayashi Danchi Uematsu
Seiji Usui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Horiba Ltd
Original Assignee
Horiba Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horiba Ltd filed Critical Horiba Ltd
Priority to DE8585102198T priority Critical patent/DE3563421D1/de
Priority to EP19850102198 priority patent/EP0192794B1/fr
Publication of EP0192794A1 publication Critical patent/EP0192794A1/fr
Application granted granted Critical
Publication of EP0192794B1 publication Critical patent/EP0192794B1/fr
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above

Definitions

  • the present invention relates to a vessel as stated in the precharacterizing portion of the single claim for preserving liquids for keeping standard solutions hermetically sealed against environmental influences and used for calibrating a calcium electrode and a pH electrode of liquid sample analyzers such as a blood analyzer.
  • a mouth portion thereof is directly connected with an analyzer b so as to feed said analyzer b with the appointed quantity of a calibrating solution contained therein at a time when said analyzer b is calibrated.
  • the conventional vessels for preserving liquids have the disadvantage that they are generally inflexible polyethylene tanks or glass bottles, and therefore, an internal air layer is expanded with the consumption of the liquid, whereby the chemical composition of the calibrating solution is changed due to the absorption of CO 2 contained in the air and also the concentration varies due to evaporation.
  • a vessel for preserving liquids for use in analyzers for liquid samples formed of a closed bag member consisting of two membrane members having very small permeability for air and water vapor and great flexibility, said membrane members are formed of a four-layer laminated membrane, respectively, consisting of an outermost polyester layer (a), an aluminum layer (b), a nylon layer (c) and an innermost plastic foil (d).
  • this vessel it is possible to control the intrusion of air thereinto from the outside as far as possible when the volume of the internal liquid is reduced (that is to say the calibrating solution contained in the vessel is consumed) and to prevent water vapor from evaporating and intruding.
  • the internal liquid may be withdrawn from the vessel by piercing the flexible wall of the container with a syringe needle.
  • the walls of the vessel are very thin, they cannot surely hold fast the needle in its position.
  • a plastic container having a mouth portion sealed with a rubber plug for forming an outlet fitting.
  • this outlet fitting has a very complicated structure and comprises an inner portion and an outer portion arranged coaxially to each other, a plug between said two portions, an integral flange at the outer end of the outer portion and a cap portion integrally connected to said integral flange via an annular web.
  • the cap portion is provided with a finger tab suitably embossed with finger gripping ribs. In the operation of the cap portion, the finger tap is grasped between the thumb and forefinger and pulled whereupon a line of severence occurs in the area of the integral web.
  • the outlet fitting is provided on a side wall of said plastic container and diagonally arranged with respect to a hanger tab equipped with an eyelet or opening for suspension of the container on a standard.
  • a solution cannot be smoothly and surely taken out from the inside of said plastic container because of improper folding conditions of said container if a diagonally arrangement of the outlet fitting and the hanger tab is used.
  • a vessel for preserving liquids is formed of a hermectically closed bag member 4 consisting of two pieces of membrane member 2, (2) provided with a mouth member 1 made of hard plastic materials, which is sealed up tightly with a rubber plug 3, fixedly adhered to the lower end portion thereof and connected with each other all over the circumference thereof.
  • 5 designates a hanging hole provided in the upper joined portion of said two pieces of membrane members 2, (2).
  • a four-layer laminated membrane consisting of the outermost polyester layer a, a vacuum deposited aluminium layer b, a nylon layer 3 (15 pm) and a low-density polyethylene layer d (100 um), the thickness of said layer a and said layer b reaching 12 11m in all, as shown in Fig. 4, is used as said membrane member 2.
  • Said membrane member 2 is made of materials having high flexibility and having superior sealing and cut off properties for air, water vapour and light at the same time.
  • a cap 6 which is provided with a small hole 6a for letting pass a syringe therethrough at the center thereof, can be screwed in said mouth member 1.
  • the solution which contains TRIS, that is to say tris(hydroxymethyl)aminomethane, as a buffering agent, is enclosed in a vessel for preserving liquids as a standard calibrating solution for calibrating of analyzers, in which for example calcium ions and pH are determined at the same time, so that said solution may be filled in said vessel in such a manner that residual air is not contained in said solution at all.
  • the calibrating solution which hardly shows an affinity to calcium ions, can be prepared by using TRIS as a buffering agent instead of those cases where BES and TES are used as buffering agents.
  • Said vessel in which the calibrating solution is enclosed in the above described manner, is connected with an analyzer 7 to calibrate said analyzer 7, as shown in Fig. 5.
  • 8 designate pipes for introducing a liquid to be tested, 9 designating a pipe for introducing the calibrating solution, 10 designating a switch valve, 11 designating a drawing pump, 12 designating a flow-through type ion electrode as a measuring member, and 13 designating a drain pipe.
  • Said vessel for preserving liquids is fixed by inserting said hanging hole 5 over a hook 14 or the like and is connected with said pipe 9 for introducing the calibrating solution of said analyzer 7 by inserting a syringe 16 provided with a connecting tube 15 into said rubber plug 3 of said mouth member 1.
  • the bag member 4 made of greatly flexible materials contracts with the reduction of the quantity of liquid contained in said vessel even though liquid contained in the vessel is consumed, the pressure inside the vessel is not reduced so much.
  • the bag member 4 is made of materials having remarkably small permeability to air and water vapour, the intrusion of air from the outside as well as the evaporation and penetration of water vapour can be satisfactorily prevented, and therefore, the composition and concentration of the liquid contained in the vessel can be held constant for a long time. Therefore, a vessel according to the present invention can be very effectively used for a highly accurate determination of liquid quantities, for calibration purposes and the like.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Laminated Bodies (AREA)

Claims (1)

  1. Récipient pour conserver des liquides destinés à l'utilisation dans des analyseurs pour échantillons liquides, constitué d'un élément de pochette fremé (4) formé de deux éléments de membrane (2) ayant une très faible perméabilité vis à vis de l'air et de la vapeur d'eau, et une grande souplesse, lesdits éléments de membrane (2) étant constitués chacun d'une membrane stratifiée à quatre couches, consistant en une couche polyester extérieure (a), une couche d'aluminium (b), une couche de nylon (c) et une feuille de plastique intérieure (d), caractérisé en ce que
    - l'élément de pochette (4) est muni d'un élément d'ouverture (1) en matière plastique dure et adhérant d'une manière fixe à la partie d'extrê- mité inférieure de ce dernier,
    - l'élément douverture (1) est fermé de manière étanche avec un bouchon de caoutchouc (3),
    - un capuchon (6), muni en son centre d'un petit trou (6a), est vissé dans ledit élément d'ouverture (1),
    - un trou de suspension (5) est prévu dans la partie supérieure raccordée desdits deux éléments de membrane (2),
    - la couche d'aluminium (6) est une couche déposée sous vide, et
    - la feuille de plastique intérieure (d) est en polyéthylène basse densité.
EP19850102198 1985-02-27 1985-02-27 Récipient pour liquides pour appareils d'analyse Expired EP0192794B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE8585102198T DE3563421D1 (en) 1985-02-27 1985-02-27 Liquid preserving vessel for use in liquid sample analyzers
EP19850102198 EP0192794B1 (fr) 1985-02-27 1985-02-27 Récipient pour liquides pour appareils d'analyse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19850102198 EP0192794B1 (fr) 1985-02-27 1985-02-27 Récipient pour liquides pour appareils d'analyse

Publications (2)

Publication Number Publication Date
EP0192794A1 EP0192794A1 (fr) 1986-09-03
EP0192794B1 true EP0192794B1 (fr) 1988-06-22

Family

ID=8193327

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850102198 Expired EP0192794B1 (fr) 1985-02-27 1985-02-27 Récipient pour liquides pour appareils d'analyse

Country Status (2)

Country Link
EP (1) EP0192794B1 (fr)
DE (1) DE3563421D1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723735B1 (fr) * 1994-08-18 1996-10-31 Abx Sa Boitier a branchement automatique pour distribution de reactifs dans un appareil notamment un analyseur hematologique.
US5710371A (en) * 1995-01-25 1998-01-20 Przedsiebiorstwo Zagraniezne Htl Container for calibrating fluids, and device and method for measuring parameters of a sample of fluid, and oxygen electrode therefor
JP3862193B2 (ja) * 1998-06-26 2006-12-27 コニカミノルタホールディングス株式会社 電子写真用現像資材の包装材料と包装方法及び電子写真現像用トナーと現像剤
FR2790681B1 (fr) * 1999-03-09 2001-05-11 Biomerieux Sa Dispositif de pompage permettant de transferer au moins un fluide dans un consommable
FR2790684B1 (fr) 1999-03-09 2001-05-11 Biomerieux Sa Appareil permettant en son sein le transfert de liquides par capillarite
EP3026437B1 (fr) 2013-07-26 2020-04-29 Sekisui Medical Co., Ltd. Appareil d'analyse d'échantillon

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3368560A (en) * 1965-10-07 1968-02-13 Theodore H. Gewecke Outlet fitting for plastic parenteral solution container
US4116336A (en) * 1975-05-30 1978-09-26 Radiometer A/S Package containing a reference liquid for blood gas equipment
DE2719113A1 (de) * 1977-04-29 1978-11-09 Sengewald Kg Karl H Verbundfolie aus kunststoffolien fuer verpackungen
JPS5512008A (en) * 1978-06-29 1980-01-28 Mitsui Petrochemical Ind Packing laminate sack
FR2508873A1 (fr) * 1981-07-06 1983-01-07 Rhone Poulenc Films Procede d'emballage de materiaux sensibles a l'oxygene et/ou a la vapeur d'eau
US4387126A (en) * 1982-02-10 1983-06-07 Champion International Corporation Laminated packaging material
FI71102C (fi) * 1982-02-25 1986-11-24 Fluilogic Systems Oy Reagensfoerpackning

Also Published As

Publication number Publication date
EP0192794A1 (fr) 1986-09-03
DE3563421D1 (en) 1988-07-28

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