EP0143796B1 - Dosage pipette - Google Patents

Dosage pipette Download PDF

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Publication number
EP0143796B1
EP0143796B1 EP84901351A EP84901351A EP0143796B1 EP 0143796 B1 EP0143796 B1 EP 0143796B1 EP 84901351 A EP84901351 A EP 84901351A EP 84901351 A EP84901351 A EP 84901351A EP 0143796 B1 EP0143796 B1 EP 0143796B1
Authority
EP
European Patent Office
Prior art keywords
dosage
rack
toothed
lever
toothing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP84901351A
Other languages
German (de)
French (fr)
Other versions
EP0143796A1 (en
Inventor
Mikael Fagerstedt
Erkki Kaski
Jukka TERVAMÄKI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Fisher Scientific Oy
Original Assignee
Labsystems Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labsystems Oy filed Critical Labsystems Oy
Priority to AT84901351T priority Critical patent/ATE31150T1/en
Publication of EP0143796A1 publication Critical patent/EP0143796A1/en
Application granted granted Critical
Publication of EP0143796B1 publication Critical patent/EP0143796B1/en
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge

Definitions

  • the invention described herein is concerned with a pipette which is provided with a piston and a cylinder and with two operating knobs, whereat, by means of one of the said knobs, the cylinder can be filled with liquid by depressing the knob once, and by means of the other one of the knobs, the cylinder can be emptied stepwise by means of successive depressions of the piston, of desired magnitude.
  • a pipette which is provided with a piston and a cylinder and with two operating knobs, whereat, by means of one of the said knobs, the cylinder can be filled with liquid by depressing the knob once, and by means of the other one of the knobs, the cylinder can be emptied stepwise by means of successive depressions of the piston, of desired magnitude.
  • the said prior-art pipettes often involve the drawback that the filling lever must be operated by lifting, whereby two hands are usually required.
  • an error is often produced when, by mistake, the last dose is also dosed, in which case the piston can no longer be displaced over a sufficiently long distance.
  • the pipette of DE-A-2926691 has a special device to prevent actuation of the piston when insufficient liquid remains.
  • DE-A-3008346 discloses a dosage pipette has been piston mounted inside a cylinder.
  • a toothed dosage rack is attached to the piston and a striking pin is engageable with the dosage toothing of the toothed dosage rack.
  • the striking pin has coupled to it a dosage button so that when the dosage button is depressed the striking pin engages and displaces the toothed rack longitudinally.
  • the toothed dosage rack is also provided with a second toothing engaged by a cog wheel. That cog wheel engages a second toothed rack which is provided with a filling pressing knob.
  • a dosage pipette provided with a handle, a cylinder attached to the handle, a piston inside the cylinder, a toothed dosage rack attached to the piston, a striking pin engageable with the dosage toothing of the said rack, the said striking pin being mounted on a dosage lever so that, when the dosage lever is depressed, the striking pin engages and displaces the toothed rack longitudinally, characterised in that, at the side of the dosage toothing, there is pivoted lifting lever, whose pivot position in relation to the toothed rack can be adjusted longitudinally as desired by means of an adjusting device and which lever is provided at the end opposite its pivot with a cam disposed to lie laterally alongside the rack teeth, and which engages the striking pin to displace it from the dosage toothing during upward movement of the striking pin and disengages thereafter, and that the toothed dosage rack is additionally provided with a second toothing, with a cogwheel resting -against the said toothing and, at the opposite side, resting against
  • the pipette is easy to operate, because it can be filled by one hand, while the other hand remains free, e.g., for the handling of test tubes.
  • the lifting-lever system described here is of simple construction and reliable in operation. By means of the cam provided at the top end of the toothed rack, it is, moreover, possible to avoid the pipetting of the last, too little dose.
  • Figure 1 is a sectional side view of an embodiment
  • Figure 2 is a certain sectional view of same as viewed from the top
  • Figure 3 shows a detail of the tip portion of a multi-tip pipette.
  • the pipette comprises an oblong handle (1), at whose lower end there is a cylinder (2), and in the cylinder a piston (3).
  • the cylinder may be attached to the handle, e.g., by means of a bayonet socket.
  • a toothed rack (4) - parallel to the handle is attached, which rack is provided with two toothings (5) and (6).
  • a striking pin (8) is pressed against the toothing (6) by the force of a spring (16), and the striking pin is mounted on a lever (9).
  • the lever (9) is mounted on a shaft (15) located in the handle.
  • the lever is connected with a spring (19), which attempts to keep the lever in its upper position. The movement of the striking pin (8) is stopped at the lower position by a limiter (18)
  • a cogwheel 7 operates in contact with the toothing 5 on the toothed rack 4, which cogwheel is mounted on a shaft 10. At the other side, the cogwheel 7 operates in contact with a toothed rack 11, whose top end is provided with a press knob 12.
  • a resilient lifting lever 20 At the side of the toothing 6 on the toothed rack 4, there is a resilient lifting lever 20 and, on the lever, a cam 21, which raises the striking pin 8 apart from the toothing 6 during the stage of upward movement of the lever 9.
  • the top end of the lifting lever is provided with a guide pin 23, which is fitted into a guide groove 25 provided in the adjusting wheel 24.
  • the adjusting wheel is mounted on a shaft 26.
  • the top end of the toothed rack 4 is additionally provided with a cam 22, which, as the toothed rack approaches its lower position, shifts the lifting lever 20 towards the striking pin 8.
  • the pipette operates so that, when the lever 9 is in its upper position and when the striking pin 8 is, consequently, apart from the toothing 6 and when the piston 3 is in the cylinder 2 in its lower position, the press knob 12 is depressed, whereat the cogwheel 7 starts revolving and lifts the toothed rack 4 and, along with the rack, the piston 3 in the cylinder 2 upwards. In this way, suction is generated in the cylinder 2, whereby the cylinder is filled with liquid 13.
  • the dosage can be started by means of the lever 9.
  • the spring 16 presses the striking pin 8 into the toothing 6, whereat the striking pin 8 starts pushing the toothed rack 4 and the piston 3 downwards until the striking pin 8 meets the limiter 18, against which the movement stops.
  • the spring 19 restores the dosage lever 9 back to its upper position upon completion of the depressing.
  • the striking pin 8 must jump over the toothing 6 until; near the upper position of the striking pin 8, the cam 21 of the resilient lifting lever 20 raises the striking pin 8 apart from the toothing 6.
  • the dosage can be repeated until the toothed rack 4 and the piston 3 approach their lower position.
  • the cam 22 at the top end of the toothed rack 4 meets the lifting lever 20 and raises it by the height of the toothing 6.
  • the cam 21 of the lifting lever 20 raises the striking pin 8 to such an extent that the striking pin no longer reaches the toothing 6 when the lever 9 is depressed again for dosage.
  • the guide groove 25 shifts the lifting lever 20 upwards or downwards by the intermediate of the pin 23, whereat, correspondingly, at the botton end of the lifting lever, the cam 21 is shifted and permits the striking pin 8 to move over the desired distance on the toothing 6, e.g. over 1, 2, 3, 4 or more teeth, per each depression of the dosage lever 9. In this way, a 1-, 2-, 3- or 4-fold dose is obtained.
  • toothings 5 and 6 are shown as located one after the other, but, if desired, they may also be very well placed side by side on the toothed rack 4.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Portable Nailing Machines And Staplers (AREA)
  • Transmission Devices (AREA)

Abstract

A pipette which is provided with a piston, with a toothed rack connected with the piston, with a striking pin resting against the toothed rack, and with a dosage lever mounted on the striking pin. By depressing the lever, the filled pipette can be emptied as successive doses of specified magnitude. The pipette is additionally provided with a lifting lever (20) placed at the side of the toothing, the distance of the said lever from the end of the toothed rack being adjustable (24) as desired and the said lever permitting the striking pin to push the toothed rack over a specified distance only. In this way, it is possible to adjust the magnitude of the emptying step as desired. Moreover, the toothed rack is provided with a second toothing (5), a cogwheel (7) resting against it and, at the other side, resting against a second toothed rack (11), whose top end is provided with a press knob (12). By pressing this knob downwards, the toothed dosage rack with its piston is shifted to its upper position, and the pipette is filled.

Description

  • The invention described herein is concerned with a pipette which is provided with a piston and a cylinder and with two operating knobs, whereat, by means of one of the said knobs, the cylinder can be filled with liquid by depressing the knob once, and by means of the other one of the knobs, the cylinder can be emptied stepwise by means of successive depressions of the piston, of desired magnitude. There may be one or several piston- cylinder assemblies.
  • Several types of such so-called step pipettes are known in prior art, e.g., a pipette in accordance with the published Finnish Patent Application Fl 802,403 orthe pipette as perthe German published Patent Application DE 2,926,691 (= GB 2,057,581). The said prior-art pipettes, however, often involve the drawback that the filling lever must be operated by lifting, whereby two hands are usually required. Moreover, when the prior-art apparatuses are used, an error is often produced when, by mistake, the last dose is also dosed, in which case the piston can no longer be displaced over a sufficiently long distance. The pipette of DE-A-2926691 has a special device to prevent actuation of the piston when insufficient liquid remains.
  • DE-A-3008346 discloses a dosage pipette has been piston mounted inside a cylinder. A toothed dosage rack is attached to the piston and a striking pin is engageable with the dosage toothing of the toothed dosage rack. The striking pin has coupled to it a dosage button so that when the dosage button is depressed the striking pin engages and displaces the toothed rack longitudinally. The toothed dosage rack is also provided with a second toothing engaged by a cog wheel. That cog wheel engages a second toothed rack which is provided with a filling pressing knob.
  • According to the present invention there is provided a dosage pipette, provided with a handle, a cylinder attached to the handle, a piston inside the cylinder, a toothed dosage rack attached to the piston, a striking pin engageable with the dosage toothing of the said rack, the said striking pin being mounted on a dosage lever so that, when the dosage lever is depressed, the striking pin engages and displaces the toothed rack longitudinally, characterised in that, at the side of the dosage toothing, there is pivoted lifting lever, whose pivot position in relation to the toothed rack can be adjusted longitudinally as desired by means of an adjusting device and which lever is provided at the end opposite its pivot with a cam disposed to lie laterally alongside the rack teeth, and which engages the striking pin to displace it from the dosage toothing during upward movement of the striking pin and disengages thereafter, and that the toothed dosage rack is additionally provided with a second toothing, with a cogwheel resting -against the said toothing and, at the opposite side, resting against a second toothed rack, which is provided with a filling press knob.
  • - The pipette is easy to operate, because it can be filled by one hand, while the other hand remains free, e.g., for the handling of test tubes. Moreover, the lifting-lever system described here is of simple construction and reliable in operation. By means of the cam provided at the top end of the toothed rack, it is, moreover, possible to avoid the pipetting of the last, too little dose.
  • The invention will be illustrated in more detail by means of the attached drawings. Figure 1 is a sectional side view of an embodiment, and Figure 2 is a certain sectional view of same as viewed from the top. Figure 3 shows a detail of the tip portion of a multi-tip pipette.
  • The pipette comprises an oblong handle (1), at whose lower end there is a cylinder (2), and in the cylinder a piston (3). The cylinder may be attached to the handle, e.g., by means of a bayonet socket. To the top end of the piston, a toothed rack (4) - parallel to the handle is attached, which rack is provided with two toothings (5) and (6). A striking pin (8) is pressed against the toothing (6) by the force of a spring (16), and the striking pin is mounted on a lever (9). The lever (9) is mounted on a shaft (15) located in the handle. Moreover, the lever is connected with a spring (19), which attempts to keep the lever in its upper position. The movement of the striking pin (8) is stopped at the lower position by a limiter (18)
  • A cogwheel 7 operates in contact with the toothing 5 on the toothed rack 4, which cogwheel is mounted on a shaft 10. At the other side, the cogwheel 7 operates in contact with a toothed rack 11, whose top end is provided with a press knob 12.
  • At the side of the toothing 6 on the toothed rack 4, there is a resilient lifting lever 20 and, on the lever, a cam 21, which raises the striking pin 8 apart from the toothing 6 during the stage of upward movement of the lever 9. The top end of the lifting lever is provided with a guide pin 23, which is fitted into a guide groove 25 provided in the adjusting wheel 24. The adjusting wheel is mounted on a shaft 26.
  • The top end of the toothed rack 4 is additionally provided with a cam 22, which, as the toothed rack approaches its lower position, shifts the lifting lever 20 towards the striking pin 8.
  • The pipette operates so that, when the lever 9 is in its upper position and when the striking pin 8 is, consequently, apart from the toothing 6 and when the piston 3 is in the cylinder 2 in its lower position, the press knob 12 is depressed, whereat the cogwheel 7 starts revolving and lifts the toothed rack 4 and, along with the rack, the piston 3 in the cylinder 2 upwards. In this way, suction is generated in the cylinder 2, whereby the cylinder is filled with liquid 13.
  • After the cylinder 2 has been filled completely and the press knob 12 is in its lower position 14, the dosage can be started by means of the lever 9. When the dosage lever 9 is depressed, the spring 16 presses the striking pin 8 into the toothing 6, whereat the striking pin 8 starts pushing the toothed rack 4 and the piston 3 downwards until the striking pin 8 meets the limiter 18, against which the movement stops. The spring 19 restores the dosage lever 9 back to its upper position upon completion of the depressing. Thereat, the striking pin 8 must jump over the toothing 6 until; near the upper position of the striking pin 8, the cam 21 of the resilient lifting lever 20 raises the striking pin 8 apart from the toothing 6.
  • The dosage can be repeated until the toothed rack 4 and the piston 3 approach their lower position. Thereat, the cam 22 at the top end of the toothed rack 4 meets the lifting lever 20 and raises it by the height of the toothing 6. Thereat, on the other hand, the cam 21 of the lifting lever 20 raises the striking pin 8 to such an extent that the striking pin no longer reaches the toothing 6 when the lever 9 is depressed again for dosage. Thereby, striking of the piston 3 against the bottom of the cylinder 2 is prevented, which striking might make the last dose inaccurate.
  • When the adjusting wheel 24 is turned, the guide groove 25 shifts the lifting lever 20 upwards or downwards by the intermediate of the pin 23, whereat, correspondingly, at the botton end of the lifting lever, the cam 21 is shifted and permits the striking pin 8 to move over the desired distance on the toothing 6, e.g. over 1, 2, 3, 4 or more teeth, per each depression of the dosage lever 9. In this way, a 1-, 2-, 3- or 4-fold dose is obtained.
  • In Figures 1 and 2, the toothings 5 and 6 are shown as located one after the other, but, if desired, they may also be very well placed side by side on the toothed rack 4.

Claims (5)

1. A dosage pipette, provided with a handle (1), a cylinder (2) attached to the handle, a piston (3) inside the cylinder, a toothed dosage rack (4) attached to the piston, a striking pin (8) engageable with the dosage toothing (6) of the said rack, the said striking pin being mounted on a dosage lever (9) so that, when the dosage lever is depressed, the striking pin engages and displaces the toothed rack longitudinally, characterised in that, at the side of the dosage toothing, there is pivoted lifting lever (20), whose pivot position - relates to the toothed rack can be adjusted longitudinally as desired by means of an adjusting device (24) and which lever is provided at the end opposite its pivot with a cam (21) disposed to lie laterally alongside the rack teeth, and which engages the striking pin to displace it from the dosage toothing during upward movement of the striking pin (8) and disengages thereafter, and that the toothed dosage rack is additionally provided with a second toothing (5), with a cogwheel (7) resting against the said toothing and, at the opposite side, resting against a second toothed rack (11), which is provided with a filling press knob (12).
2. Pipette as claimed in Claim 1, characterised in that the top end of the toothed dosage rack is provided with a cam (22), which, when the toothed dosage rack approaches its lower position, pushes the lifting lever towards the striking pin so that the lifting lever prevents the striking pin from reaching contact with the toothing.
3. Pipette as claimed in Claim 1 or 2, characterised in that the toothings on the toothed dosage rack are placed side by side.
4. Pipette as claimed in Claim 1 or 2, characterised in that the toothings on the toothed dosage rack are placed one after the other.
5. Pipette as claimed in any of Claims 1 to 4, characterised in that the filling press knob is placed at the side of the handle.
EP84901351A 1983-04-13 1984-03-29 Dosage pipette Expired EP0143796B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT84901351T ATE31150T1 (en) 1983-04-13 1984-03-29 DOSING PIPETTE.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI831239 1983-04-13
FI831239A FI831239A0 (en) 1983-04-13 1983-04-13 DOSERINGSPIPETT

Publications (2)

Publication Number Publication Date
EP0143796A1 EP0143796A1 (en) 1985-06-12
EP0143796B1 true EP0143796B1 (en) 1987-12-02

Family

ID=8517044

Family Applications (1)

Application Number Title Priority Date Filing Date
EP84901351A Expired EP0143796B1 (en) 1983-04-13 1984-03-29 Dosage pipette

Country Status (7)

Country Link
EP (1) EP0143796B1 (en)
JP (1) JPS60501048A (en)
DE (1) DE3467860D1 (en)
FI (1) FI831239A0 (en)
IT (1) IT1178875B (en)
SU (1) SU1373300A3 (en)
WO (1) WO1984004056A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202010010942U1 (en) 2010-08-03 2011-11-08 Brand Gmbh + Co Kg Pipette for a pipette system with pipette and syringe

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728501A (en) * 1984-07-27 1988-03-01 Minoru Atake Adjustable liquid sampling apparatus
US4929428A (en) * 1988-02-19 1990-05-29 Fuji Photo Film Co., Ltd. Quantitative pipette
DE4141608C2 (en) * 1991-12-17 1993-12-02 Eppendorf Geraetebau Netheler Pipetting device
FI921648A0 (en) * 1992-04-13 1992-04-13 Labsystems Oy STEGPIPETT.
US5364596A (en) * 1992-12-01 1994-11-15 Rainin Instrument Co., Inc. Manual pipette with plunger velocity governor, home position latch and trigger release
FI931806A0 (en) * 1993-04-21 1993-04-21 Labsystems Oy KOLVPIPETT
DE9415847U1 (en) * 1994-09-30 1994-12-08 Ritter, Ralf, 86150 Augsburg Repeater pipette
FI961649A0 (en) * 1996-04-15 1996-04-15 Labsystems Oy Spaerrpipett
FR2762671B1 (en) * 1997-04-29 1999-07-16 D Autry Eric Marteau DEVICE FOR DISPENSING SUCESIVE VOLUMES OF LIQUID WITH MAGNETIC HANGING ELEMENT
GB2511644B (en) * 2012-07-26 2017-03-22 Ttp Labtech Ltd Liquid dispensing device
DE102014109345A1 (en) * 2014-07-04 2016-01-07 Eppendorf Ag Pipette for actuating a syringe
BE1022747A9 (en) * 2015-02-27 2016-10-03 Pilipili Productontwerp Nv ACTIVATOR FOR BUILDING UP AND RELEASING A SURE POWER
EP4406655A2 (en) * 2020-06-22 2024-07-31 Eppendorf SE Pipette for use with a pipette tip or syringe having a piston and a cylinder

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2926691C2 (en) * 1979-07-02 1983-05-26 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Repeater pipette
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
FI60137C (en) * 1979-03-23 1981-12-10 Suovaniemi Finnpipette pipette
FI58875C (en) * 1979-08-31 1981-05-11 Suovaniemi Finnpipette pipette
JPS6035458B2 (en) * 1980-08-02 1985-08-14 アイシン精機株式会社 embroidery frame

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202010010942U1 (en) 2010-08-03 2011-11-08 Brand Gmbh + Co Kg Pipette for a pipette system with pipette and syringe
EP2415525A2 (en) 2010-08-03 2012-02-08 Brand GmbH + Co KG Pipette for a pipette system with pipette and syringe
EP2415525A3 (en) * 2010-08-03 2014-07-02 Brand GmbH + Co KG Pipette for a pipette system with pipette and syringe

Also Published As

Publication number Publication date
FI831239A0 (en) 1983-04-13
EP0143796A1 (en) 1985-06-12
IT8467229A0 (en) 1984-03-12
IT8467229A1 (en) 1985-09-12
IT1178875B (en) 1987-09-16
JPS60501048A (en) 1985-07-11
SU1373300A3 (en) 1988-02-07
WO1984004056A1 (en) 1984-10-25
DE3467860D1 (en) 1988-01-14

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