EP0138905A1 - A double lumen cannula and its method of manufacture - Google Patents
A double lumen cannula and its method of manufactureInfo
- Publication number
- EP0138905A1 EP0138905A1 EP84901264A EP84901264A EP0138905A1 EP 0138905 A1 EP0138905 A1 EP 0138905A1 EP 84901264 A EP84901264 A EP 84901264A EP 84901264 A EP84901264 A EP 84901264A EP 0138905 A1 EP0138905 A1 EP 0138905A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- distal end
- lumen
- bore
- tubular member
- forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M5/1582—Double lumen needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
- A61M2025/0031—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M2025/0037—Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
Definitions
- the invention generally relates to medical purpose cannulas. More specifically, the invention relates to medical purpose cannulas having two lumens.
- the present medical concensus is that care of a patient is improved by providing only the therapeutic components of whole blood which are required to treat the specific disease.
- This form of treatment is generally referred to as blood component therapy.
- continuous flow extracorporeal blood processing procedures can help to offset the limited supply of blood components available for therapeutic purposes.
- whole blood is continuously drawn from a donor.
- the plasma and plasma-based fractions are separated and collected.
- the remaining red blood cells are returned to the donor. Because red blood cells are being continuously returned to the donor, relatively large total volumes of whole blood can be withdrawn for processing. This can result in significantly larger yields of plasma and/or plasma-based fractions, compared to the yields of a single unit, batch collection procedure.
- a continuous flow procedure requires two separate fluid paths be established between the processing device and the circulatory system of the donor: one to draw whole blood from the donor for processing, and one to return the red blood cells to the donor after processing.
- two separate phlebotomies are performed to insert a single lumen needle into each of the donor's arms.
- One double lumen phlebotomy needle can, in theory, accommodate these two opposite flow paths and can thereby reduce the number of venipunctures necessary to perform a continuous flow procedure.
- the use of double lumen needles in continuous flow blood separation and collection procedures is virtually nonexistent. This is because, for the most part, blood collection and separation procedures use volunteer donors, and most conventional double lumen needles are relatively large in size and hence discomforting to a donor, both from a physical and a psychological standpoint.
- the portion of a conventional double lumen needle assembly which enters the arm typically has an overall outside diameter which is equal to or larger than .095 inch (i.e., less than 13 gauge).
- a conventional single lumen needle has an overall outside diameter of only between .059 inch (17 gauge) and .072 inch (15 gauge). It is not surprising, then, that most blood donors would not favor the use of these larger dual lumen needles.
- another desirable feature of a double lumen needle is its ability to effectively isolate the two, usually opposite, fluid flow patterns which it is designed to accommodate. To optimize the performance of the needle, it is desirable to prevent mixing or recirculation of the two opposite fluid flows.
- a double lumen cannula Yet another desirable feature of a double lumen cannula is its ease_ of operation.
- Many conventional double lumen needles include an obturator to perform the venipuncture as well as to control fluid flow through the needle. The use of an obturator can complicate the operation of the needle, as well as increase its overall size.
- Another principal object of this invention is to provide a double lumen needle which effectively isolates fluid flow patterns in a simple and straightforward manner.
- Still another principal object of the invention is to provide a double lumen needle which is easy to use.
- Yet another principal object of this invention is to provide a double lumen needle which lends itself to straightforward, economical manufacturing techniques.
- the divider member includes a crimped end portion which is positioned adjacent to the one distal end of the bore which is intended to enter the donor during venipuncture.
- the crimped end portion is bent at an angle relative to the axis of the bore and is pressed into sealing engagement against a portion of the bore sidewall. The crimped end portion blocks fluid flow between the first lumen and the one distal end, while affording fluid flow between the second lumen and the one distal end.
- the cannula also preferably includes in the vicinity of the one distal end a first opening which communicates with the first lumen.
- the opening is axially spaced an effective distance away from the one distal end to isolate the flow of fluid through the opening from the flow of fluid through the one distal end.
- the divider member includes a second crimped end portion which is positioned adjacent to the other distal end of the bore which is intended to communicate with external tubing.
- the second crimped end portion blocks fluid flow between the second lumen and the other distal end, while affording fluid flow between the first lumen and the other distal end.
- a second opening is formed in the vicinity of the other distal end to open communication with the second lumen.
- Fig. 1 is a perspective view of a double lumen cannula and hub assembly which embodies the features of the invention
- Fig. 1; Fig. 3 is an enlarged top view, with portions broken away and in section, of the double lumen cannula which is associated with the assembly shown in Fig. 1 and which embodies the features of the invention;
- Fig. 4 is a section view of the cannula taken generally along line 4-4 in Fig. 3;
- Fig. 5 is a bottom view of the cannula shown in Fig. 3; -% -
- Fig. 6 is a cross section view of the cannula taken along line 6-6 in Fig. 4;
- Fig. 7 is an enlarged view, with portions broken away and in section, of the operative end of the cannula shown in Fig. 3;
- Fig. 8 is a diagrammatic view of the double lumen cannula and hub assembly shown in Figs. 1 and 2 in association with a continuous flow blood processing system;
- Fig. 9 is a alternate side opening arrangement for the cannula shown in Fig. 3;
- Fig. 10 is a section view taken generally along line 10-10 in Fig. 9;
- Fig. 11 is an alternate side opening arrangement for the cannula shown in Fig. 3;
- Figs. 12 and 13 are perspective views of the cannula shown in Figs. 3 through 7 in the process of being assembled;
- Fig. 15 is a perspective view of a double lumen cannula which embodies features of the invention but which is assembled different than as shown in Figs. 12, 13, and 14; and
- Figs. 16 through 18 are section views of the cannula as shown in either Figs. 13, 14, or 15 in the process of having the crimped end portions formed;
- Figs. 20a and 20b are perspective views of a double lumen cannula, respectively before and after assembly, which embodies the features of the invention but which are assembled differently than as shown in Figs. 12 and 13, 14, and 15; and
- Figs. 21a and 21b are perspective views of a double lumen cannula, respectively before and after assembly, which embodies features of the invention but which are assembled differently as shown in Figs. 12 and 13, 14, 15, and 20a and 20b.
- FIGs. 1 and 2 A hub and cannula assembly 10 is shown in Figs. 1 and 2.
- the term "cannula” broadly signifies a relatively small tube which is insertable into a body cavity, duct, or vessel.
- the assembly includes a hub 12 and a cannula 14.
- the hub 12 is preferably compact in size (see Fig. 1) so it can be easily handled and manipulated between the fingertips of an attendant.
- the hub 12 includes a bore 16 which accommodates the cannula 14 with an operative end 18 of the cannula 14 supported in an outwardly projecting, exposed position.
- the hub 12 also includes a pair of internal fluid passages 20 and 22 which, at one end (respectively 20a and 22a), communicate with the interior fluid paths of the cannula 14 and which, ' at the other end (respectively 20b and 22b), are attachable to conventional tubing 24 and 26.
- the assembly 10 preferably includes a cover 28.
- the cover 28 is removably attachable and reattachable about a post 30 formed on the hub 12. -iL -
- the hub 12 may be variously constructed, it is preferably molded of a plastic material which is capable of withstanding sterilization, such as by autoclaving, radiation, or the use of ethylene oxide, with no loss of function or evidence of distortion.
- the material of the hub 12 is also preferably bondable, such as by solvent bonding, to conventional polyvinyl chloride tubing.
- Candidates for the hub material include polyvinyl chloride, as well as a thermoplastic copolyetherester manufactured and sold by E. I. DuPont under the trademark HYTREL 4056.
- the cannula 14 is preferably made of medically approved stainless steel.
- the cannula 14 may be attached to the bore 16 of the hub 12 by various methods, such as solvent or induction bonding or resistance welding.
- the cannula 14 comprises a tubular member 36 and a divider member 38 (see Figs. 4, 6, and 7).
- the tubular member 36 includes a sidewall 40 which circumferentially defines an axial bore 42 having oppositely spaced distal ends 44 and 46.
- a beveled surface 48 is formed having a rearward edge 50 and a forward edge 52. The forward edge 52 terminates in a sharpened point 54
- distal end 44 which constitutes the heretofore identified operative end 18 of the cannula 14.
- distal end 46 is carried within the bore 16 of the hub 12.
- the divider member 38 includes a main body portion 60 which extends generally parallel to the axis of the bore 42 between the two distal ends 44 and 46.”
- the side edges 62 and 64 of the main body portion 60 extend along diametrically opposite portions of the bore 16.
- one side edge 64 abuts snugly against the bore sidewall 40, while the other side edge 62 extends into the bore sidewall 40 (see also Fig. 7).
- a method of manufacturing the cannula 14 as shown in these figures will be described in greater detail later.
- the divider member 38 forms an essentially fluid tight interface between the first and second lumens 32 and 34 along the axial length of the bore 42.
- the main body portion 60 preferably extends transversely of the slope of the beveled edge 48, with the centerline 66 of the main body portion 60 generally axially aligned with the centerline 56 of the sharpened point.
- Other interior configurations are possible, however, depending upon the environment in which the cannula 14 is to be used.
- the fluid flow patterns in the cannula 14 will proceed in opposite directions, with one lumen directing fluid into the cannula 14 and the other lumen directing fluid out of the cannula 14.
- the openings through which the lumens 32 and 34 direct fluids into and out of the cannula 14 are physically spaced and isolated from each other.
- an end 68 of the divider member 38 adjacent to the one distal end 44 is crimped into contact with an arcuate portion 70 of the sidewall 40.
- the crimped end portion 68 is bent at an angle relative to the axis of the bore 42.
- the terminus 72 of the crimped end portion 68 is pressed into firm surface engagement against the arcuate portion 70 of the bore sidewall 40 (see, in particular, Fig. 4).
- the crimped end portion 68 is thereby held in a state of compression between the main body portion 60 and the arcuate sidewall portion 70, against which the terminus 72 is pressed. An essentially fluid-tight seal is thus formed at the interface between the terminus 72 and arcuate sidewall portion 70.
- the crimped end portion 68 is preferably bent toward the sharpened point 54.
- the presence of the crimped end portion 68 of the divider member 38 serves alone to block fluid flow between the first lumen 32 and the one distal end 44, while affording fluid flow between the second lumen 34 and the one distal end 44.
- the crimped end portion 68 obviates the need for inserting a separate plug or closure member into the bore 42 for this purpose.
- means is provided for forming an opening 74 in the vicinity of the one distal end 44.
- the opening 74 communicates only with the first lumen 32.
- this opening 74 is formed in the sidewall 40 of the tubular member 36 and is purposely isolated from the distal end 44, with which only the second lumen 34 communicates, both in terms of distance and in terms of attitude.
- the formed opening 74 is positioned generally axially along the centerline 52 of the sharpened point 54 at a predetermined distance away from the sharpened point 54.
- the distance from the sharpened point 54 should be no closer than and preferably behind the rearward edge 50 of the beveled surface 48 (see Fig. 4) .
- the crimped end portion 68 is formed closely adjacent to the opening 74. This relationship minimizes the size of the area lying between the opening 74 and the terminus 72 of the crimped end portion 68. This, in turn, minimizes the chance that a volume of blood could become entrapped in this "dead" area and form a clot.
- the axis 76 of the opening 74 extends generally at a right angle to the fluid path in the second lumen 34. Fluid flow through the opening 74 thus proceeds away from and generally at a right angle relative to the fluid flow through the one distal end 44.
- Fluid flow patterns in the region of the distal end 44 are therefore not only physically spaced from each other, but they are in different directions as well (see Fig. 8). The chance of mixing or recirculation of fluids between the flow paths in this region is thereby minimized to the fullest extent possible.
- the opening through which the lumens 42 and 44 direct fluid into and out of the cannula 14 in the region of the other distal end 46 are also spaced and isolated from each other.
- the end 78 of the divider member 38 which is adjacent to the other distal end 46, is crimped into contact with another arcuate portion 80 of the bore sidewall 40.
- This second crimped end portion 78 like the first described crimped end portion 68, is bent at an angle relative to the axis 58 of the bore 42 toward the arcuate portion 80 of the bore sidewall 40.
- the terminus 82 of the second crimped end portion 78 is also firmly pressed into surface engagement against the sidewall portion 80.
- the second crimped end portion 78 like the first crimped end portion 68, is thereby held in a state of compression between the main body portion 60 and the sidewall portion 80 against which the terminus 82 is pressed. An essentially fluid-tight seal is formed at the interface between the terminus 82 and the arcuate sidewall portion ' 80.
- the second crimped end portion 78 of the divider member 38 thereby blocks fluid flow between the second lumen 34 and the other distal end 46, while affording fluid flow between the first lumen 44 and the other distal end 46.
- Means is also provided for forming a second opening 84 in the vicinity of the other distal end 46. The second opening 84 communicates only with the second lumen 34.
- the second opening 84 is formed in the sidewall 40 of the tubular member 36 and is spaced axially away from the adjacent distal end 46.
- the second opening 84 also has an axis 86 (see Fig. 4) which extends generally at a right angle to the fluid path through the first lumen 32.
- the second crimped end portion 78 can be bent against an arcuate portion of the sidewall 40 which is opposite to the one 80 shown in Fig. 4. In this arrangement, the location of the second opening 84 would likewise be switched to a diametrically opposite sidewall portion.
- the fluid passages 20 and 22 in the hub 12 can extend in spaced apart paths to communicate, respectively, with the other distal end 46 (i.e., with the first lumen 32) and the second opening 84 (i.e., with the second lumen 34).
- the double lumen cannula and hub assembly 10 as heretofore described is applicable for use in a diverse number of environments. Since the assembly 10 is particularly by well suited for use in conjunction with a continuous flow blood processing procedure, this specific use is shown in Fig. 8 for illustration purposes.
- the sharpened end 44 of the cannula 14 is shown inserted into a vein 88 (typically in the arm 89 of a donor). While the cannula 14 can be inserted into the vein in various ways, in the illustrated embodiment, the sharpened end 44 faces away from the heart, i.e., the one distal end 44 generally faces into the direction of venous blood flow. This attitude is generally referred to as a "reverse phlebotomy".
- the hub 12 (see, in addition, Fig. 2) preferably includes a generally planar base portion 90 which extends at a small acute angle (i.e., equal to or less than about 10°) away from the axis of the bore 42 of the cannula 14, designated by angle "A" in Fig. 2. This assists the operator in establishing the proper venipuncture position, as shown in Fig. 8.
- negative pressure is applied by the associated processing device 94 to draw whole venous blood through the one distal end 44 of the cannula 14 into the second lumen 34.
- the whole blood exits the second lumen 34 through the second opening 84 and enters the tubing 24 attached to the hub 12. It then proceeds into the processing device 94.
- the continuous flow device 94 is a CS-3000® Blood Cell Separator, which is manufactured and sold by Fenwal Laboratories, a division of Travenol Laboratories, Inc.
- the assembly 10 can include conventional luer connectors 96 (see Fig. 2) at the terminus of the each of the tubing 24 and
- a icroporous barrier 98 or the like can be removably inserted within each luer connector 96 to protect the sterile integrity of the assembly 10 prior to use.
- the whole blood is separated by centrifugation into red blood cells and platelet-rich plasma.
- the platelet-rich plasma can be further separated into platelets and platelet-poor plasma. These components are retained for storage.
- the red blood cells are returned to the donor through the tubing 26 attached to the hub 10 and into the other distal end 46 of the cannula 14.
- the red blood cells proceed through the first lumen 32 and flow out into the vein through the first opening 74.
- the outgoing flow of red blood cells is directed away from the incoming flow of whole blood because of the purposeful positioning of the first opening 74 away from the one distal end 44.
- the configuration of the first opening 74 can be other than as shown in Figs. 3 through 7.
- the first opening 74 can take the form of a plurality of smaller openings 74a.
- the first opening 74 can also include an overlying dome 100 to prevent the vein 88 from entering and completely occluding the opening 74.
- the double lumen cannula 14 which-embodies the features of the invention can be formed in a relatively small size, compared with conventional dual lumen cannulas.
- the double lumen cannula 14 provided by this invention can equal the exterior dimensions of a conventional single lumen needle.
- FIGs. 12 through 19 illustrate a representative method of manufacturing the cannula 14 as heretofore described and shown in Figs. 1 through 7.
- this representative method includes the initial steps of forming the tubular member 36 and inserting the divider member 38 to form the two independent lumens 32 and 34.
- this representative method at most, only one side edge 62 or 64 of the divider member 38 is permanently attached in some manner to the tubular member 36. The other side edge or edges make only snug, frictional engagement with the interior sidewall 40 of the tubular bore 42. This arrangement facilitates the bending of the end portions 68 and 78 of the divider member 38 into the desired configuration during a subsequent step in the method.
- the method includes the step of forming from a sheet 102 of medically approved stainless steel the tubular member 36 having a slot 104 which extends along its axial length.
- the tubular member 36 can be roll formed into this configuration by conventional techniques.
- the tubular member 36 as shown in Fig. 12 can be formed with a relatively large outer diameter and drawn down to the desired dimension using conventional techniques.
- the representative method next includes the step of inserting the planar divider member 38 into the bore 42.
- the divider member 38 takes the form of a continuous, thin strip 106 of stainless steel which is inserted through the slot 104.
- the strip 106 has a width (designated by the letter "W" in Fig. 12) which generally equals the
- rollers 108 or the like are preferably employed to press the divider strip 106 securely into the bore 42, so that one side edge of the strip (i.e., side edge 64) makes firm frictional sealing engagement against the sidewall portion opposite to the slot 104.
- the crimping surface 120 contacts the adjacent terminus 72 and 82.
- Each terminus 72 and 82 is progressively bent and pressed into engagement between the crimping surface 120 and the respective arcuate sidewall portion 70 and 80.
- a pair of crimping members 118 may be operated simultaneously, as shown in Figs. 17 and 18. Alternately, a single crimping member 118 may be used in succession to individually form each of the crimped end portions 68 and 78.
- the dual lumen cannula which embodies the features of the invention accommodated flow rates of whole blood to the filtration device of between approximately 20 and 75 milliliters per minute, with the resulting flux of noncellular components through the pores of the microporous material ranging between 20 and 25 milliliters per minute. No hemolysis was observed.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Une canule (14) comporte un élément tubulaire (36) possédant une chambre cylindrique (42) qui est divisée en deux passages (32, 34) par un élément (38) s'étendant dans la chambre cylindrique (42). L'élément diviseur (38) est serti en contact étanche contre la paroi latérale (40) de la chambre cylindrique aux extrémités distales (44, 46) de la chambre cylindrique (42). Les parties terminales serties (68, 78) servent à enfermer un passage différent à chaque extrémité distale. Des ouvertures (74, 84) sont pratiquées dans la paroi latérale (40) de la chambre cylindrique (42) à proximité de chaque extrémité distale (44, 46) afin de permettre une communication avec le passage scellé associé. Le mélange ou la recirculation entre les chemins de fluide à travers les passages (32, 34) est ainsi minimalisé autant que possible à chaque extrémité distale (44, 46).A cannula (14) has a tubular member (36) having a cylindrical chamber (42) which is divided into two passages (32, 34) by a member (38) extending into the cylindrical chamber (42). The dividing element (38) is crimped in sealing contact against the side wall (40) of the cylindrical chamber at the distal ends (44, 46) of the cylindrical chamber (42). The crimped end portions (68, 78) serve to enclose a different passage at each distal end. Openings (74, 84) are made in the side wall (40) of the cylindrical chamber (42) near each distal end (44, 46) to allow communication with the associated sealed passage. Mixing or recirculation between the fluid paths through the passages (32, 34) is thus minimized as much as possible at each distal end (44, 46).
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48554283A | 1983-04-15 | 1983-04-15 | |
US485542 | 1995-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0138905A1 true EP0138905A1 (en) | 1985-05-02 |
Family
ID=23928563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP84901264A Withdrawn EP0138905A1 (en) | 1983-04-15 | 1984-02-23 | A double lumen cannula and its method of manufacture |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0138905A1 (en) |
JP (1) | JPS60501042A (en) |
IT (1) | IT1176031B (en) |
WO (1) | WO1984004043A1 (en) |
ZA (1) | ZA841934B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4770652A (en) * | 1985-02-12 | 1988-09-13 | Mahurkar Sakharam D | Method and apparatus for using dual-lumen catheters for extracorporeal treatment |
US4675004A (en) * | 1985-04-16 | 1987-06-23 | Quinton Instrument Company | Dual-lumen fistula needle |
US4961809A (en) * | 1988-04-21 | 1990-10-09 | Vas-Cath Incorporated | Method of producing a dual lumen catheter including forming a flare |
US5348536A (en) * | 1993-08-02 | 1994-09-20 | Quinton Instrument Company | Coextruded catheter and method of forming |
US5403291A (en) * | 1993-08-02 | 1995-04-04 | Quinton Instrument Company | Catheter with elongated side holes |
US5556390A (en) * | 1995-03-07 | 1996-09-17 | Quinton Instrument Company | Catheter with oval or elliptical lumens |
DE69637829D1 (en) * | 1995-09-21 | 2009-03-12 | Covidien Ag | Cone-shaped reinforced catheter |
US6991614B2 (en) | 1995-11-07 | 2006-01-31 | Boston Scientific Scimed, Inc. | Ureteral stent for improved patient comfort |
FR2770409B1 (en) * | 1997-10-31 | 2000-06-23 | Soprane Sa | UNIVERSAL CATHETER |
EP1258261A1 (en) * | 2001-05-15 | 2002-11-20 | Catarsi Ing. Piero & C. S.r.l. | Dialysis needle |
GB2422410B (en) * | 2005-01-19 | 2010-06-23 | Anaesthetic Medical Systems Ltd | An intravenous connector device |
WO2010095128A2 (en) | 2009-02-20 | 2010-08-26 | Omrix Biopharmaceuticals Ltd. | Device for administering an at least two-component substance |
US10549075B2 (en) * | 2015-09-09 | 2020-02-04 | M Micro Technologies, Inc. | Medical guidewire dispenser |
JP6589073B2 (en) | 2017-07-05 | 2019-10-09 | オリンパス株式会社 | Connection device and connection device set |
AU2019201164B1 (en) * | 2019-02-19 | 2020-07-23 | Winter, Paul Nicholas MR | A hypodermic device, that by itself can replace a needle for distributing dense fluids along a length of tissue thereby easing pain and when in the format of length adjustable perfuser/drainers(s) can perfuse or drain specified thicknesses of tissue while at the same time protect overlaying tissues by a length adjustable shield. The Perfudrain can be set up as a system using multiple perfuser/drainers and shields. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2175726A (en) * | 1938-11-26 | 1939-10-10 | American Anode Inc | Catheter for bronchospirometry |
US4098275A (en) * | 1975-11-28 | 1978-07-04 | Dante Vincent Consalvo | Dual flow cannula set |
US4134402A (en) * | 1976-02-11 | 1979-01-16 | Mahurkar Sakharam D | Double lumen hemodialysis catheter |
NO139201C (en) * | 1977-04-05 | 1979-01-24 | Lars Grimsrud | DEVICE FOR DIVISION OF A HOLE CANNULAL NEEDLE |
US4120068A (en) * | 1977-04-18 | 1978-10-17 | Philip Michael Kaczmarek | Rally wheel cleaning implement |
US4403983A (en) * | 1981-11-06 | 1983-09-13 | Shiley Incorporated | Dual lumen subclavian cannula |
-
1984
- 1984-02-23 WO PCT/US1984/000262 patent/WO1984004043A1/en not_active Application Discontinuation
- 1984-02-23 JP JP59501251A patent/JPS60501042A/en active Pending
- 1984-02-23 EP EP84901264A patent/EP0138905A1/en not_active Withdrawn
- 1984-03-15 ZA ZA841934A patent/ZA841934B/en unknown
- 1984-04-12 IT IT20511/84A patent/IT1176031B/en active
Non-Patent Citations (1)
Title |
---|
See references of WO8404043A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1984004043A1 (en) | 1984-10-25 |
IT1176031B (en) | 1987-08-12 |
IT8420511A0 (en) | 1984-04-12 |
JPS60501042A (en) | 1985-07-11 |
ZA841934B (en) | 1984-10-31 |
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