EP0032544A1 - Fixed angle rotor for ultra centrifuge - Google Patents
Fixed angle rotor for ultra centrifuge Download PDFInfo
- Publication number
- EP0032544A1 EP0032544A1 EP80107484A EP80107484A EP0032544A1 EP 0032544 A1 EP0032544 A1 EP 0032544A1 EP 80107484 A EP80107484 A EP 80107484A EP 80107484 A EP80107484 A EP 80107484A EP 0032544 A1 EP0032544 A1 EP 0032544A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- sample tube
- tube
- closure device
- abutment
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
Definitions
- the invention relates to a closure device for centrifuge sample tubes with an insertion part extending partially from the opening into the interior of the sample tube, the outer diameter of which corresponds in its lower part, which is essentially intended for insertion into the sample tube, to the inner diameter of the sample tube.
- Conventional closure caps for sample tubes which are used in fixed-angle rotors of ultracentrifuges, generally consist of an insertion part for insertion into the opening of the sample tube and a clamping device with which the edge of the sample tube is clamped in the closure device and in this way a firm and tight connection between the sample tube and the closure device.
- the insert part is in its lower, for insertion into the opening of the sample tube cylindrical area with an outer diameter corresponding to the inner diameter of the tube.
- the cylindrical part has a thinner shoulder, which is threaded.
- the clamping device usually contains a cover which has a conical surface which is inclined outwards or inwards and which is screwed to the plug-in part using a nut which matches the thread.
- the edge of the sample tube is pressed either inwards against a corresponding conical surface at the upper edge of the cylindrical area of the plug-in part or with the help of an O-ring seal outwards against a corresponding cylindrical extension of the lid.
- the aim of the present invention was a simplified closure device which does not have the disadvantages of the known closure devices and nevertheless offers the same safety as is necessary with conventional devices of this type for use in ultracentrifuges.
- the outer diameter of the insert part in its upper part which is essentially outside the tube, is larger than the inside diameter of the tube and outside the tube there is an abutment against which the edge of the sample tube from the insert part under the effect of the Centrifugal force is pressed.
- the abutment preferably has a conical or flat ring surface which is concentric with the axis of the sample tube.
- the abutment can consist of a ring to be pushed from below over the sample tube.
- the abutment can be formed in the rotor itself.
- the sample tubes usually made of plastic can either have an opening edge without additional reinforcement, or can be provided with a bead-like reinforcement or a type of flange. If no additional precautions are taken at the edge of the sample tube, the plug-in part must have an additional thickening in the upper area of the part to be inserted into the tube, by means of which the sample tube is expanded so that a conical surface corresponding to the abutment is created on its outer diameter.
- the closure device 1 shown in perspective in FIG. 1 is attached to a sample tube 2 and consists of an insertion part 3 and a clamping ring 4.
- the insertion part 3 has a cylindrical lower part 5 provided for insertion into the sample tube 2, the outside diameter of which corresponds to the inside diameter of the sample tube 2 .
- the likewise cylindrical upper part 6 of the insertion part located outside the sample tube has a diameter that is larger is the inside diameter of the sample tube. Between the two areas there is a shoulder 7 on which the upper edge of the sample tube 2 is in contact.
- the lower part 5 of the plug-in part 3 has an area 8, the outside diameter of which is somewhat larger than the inside diameter of the sample tube 2, but only so large that the area 8 can still be inserted into the same by widening the sample tube. Between the thickened area 8 of the lower part 5 and a thinner area there is a transition zone 9 which has a conical shape.
- the attached sample tube 2 assumes the contour of the transition zone 9 and the expanded area 8 in its upper edge area.
- the second part of the closure device consists of the ring 4, which surrounds the insertion part 3 and the upper edge of the sample tube from the outside.
- the inner contour of the ring 4 corresponds to the contour of the sample tube pushed onto the insertion part 3, i.e. the inner surface of the ring 4 is initially - cylindrical with a diameter that corresponds to the outer diameter of the sample tube, then conical and then again cylindrical with an inner diameter that corresponds to the outer diameter of the upper part 6.
- the exact diameters of the conical and cylindrical regions of the plug-in part 3 and the ring 4 are matched to one another and to the wall thickness of the sample tube 2 in such a way that the upper edge of the sample tube is clamped in by the assembly of the closure device.
- the sample tube sealed in this way is inserted into a corresponding chamber of a fixed-angle rotor.
- the rotor chamber is designed in such a way that it precisely receives the sample tube 2 with its lower part and, where the lower edge of the ring 4 is located when the sample tube is inserted, has a shoulder that supports the ring 4.
- the conical area of the inner wall of the ring 4 forms an abutment during centrifugation, against which the plug-in part 3 with its conical area 9 presses the corresponding wall zone of the sample tube 2 due to the centrifugal force.
- the connection between the closure device and the sample tube becomes better and better as the centrifuge speed increases as a result of the increasing centrifugal force.
- the sample tube 2 has a circumferential thickening 10 with a conical lower surface at its upper edge. Since the conical surface on the sample tube already exists in this version, the insertion part 3 can be made simpler by dispensing with the thickened zone 8 and the conical transition region 9.
- the ring 4 however, in turn has a corresponding conical inner surface against which the circumferential bead 10 of the sample tube through the centri force is pressed during centrifugation.
- Figure 2a) it can also be seen how the ring 4 rests with its underside on the shoulder 11 of the rotor chamber.
- Figure 2b shows a further simplified closure device, which only consists of the plug-in part 3. In its lower part, this again has the thickened zone 8 and the conical transition zone 9 of the version shown in FIG. 1. In this embodiment, however, a corresponding conical surface 12 of the wall of the rotor chamber takes the place of the ring. The conically widened area of the sample tube is pressed against this conical surface 12 by the centrifugal force.
- FIG. 2 c shows an embodiment in which the sample tube has a circumferential flange 13 at its upper edge.
- This flange which is flat in the embodiment shown in FIG. 2c), lies on a corresponding flat surface of the ring 4 and is pressed against this flat surface of the ring during centrifugation.
- the ring 4 could of course also be dispensed with if the corresponding abutment surface is provided in the rotor chamber itself.
- closure device For the closure device according to the invention, the same materials come into question as are used for conventional closure devices, that is to say preferably aluminum or titanium.
- the closure device according to the invention is considerably simplified compared to the known closure devices. So it consists of only two parts, in some embodiments even only one part. Above all, handling is extremely simplified.
- the plugging and, if necessary, the opening of the ring are operations which can be carried out in the order of seconds.
- the attachment of a closure device of the known type was a work step that required at least ten times the time.
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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Abstract
Verschlußvorrichtung für Zentrifugen-Probenröhrchen (2) mit einem sich teilweise von der Öffnung in den Innenraum des Probenröhrchens erstreckenden Einsteckteil (3), dessen Außendurchmesser in seinem unteren, im wesentlichen zur Einführung in das Probenröhrchen bestimmten Teil (5) dem Innendurchmesser des Röhrchens entspricht, dadurch gekennzeichnet, daß der Außendurchmesser des Einsteckteils in seinem oberen, im wesentlichen außerhalb des Röhrchens befindlichen Teil (6) größer ist als der Innendurchmesser des Röhrchens, und außerhalb des Röhrchens ist ein Widerlager vorhanden, gegen das unter der Wirkung der Zentrifugalkraft der Rand des Probenröhrchens vom Einsteckteil gepreßt wird.Closure device for centrifuge sample tubes (2) with an insertion part (3) partially extending from the opening into the interior of the sample tube, the outer diameter of which corresponds in its lower part (5), which is essentially intended for insertion into the sample tube, to the inner diameter of the tube, characterized in that the outer diameter of the male part in its upper part (6), which is substantially outside the tube, is larger than the inner diameter of the tube, and outside the tube there is an abutment against which, under the action of the centrifugal force, the edge of the sample tube is pressed by the plug-in part.
Description
Die Erfindung betrifft eine Verschlussvorrichtung für Zentrifugen-Probenröhrchen mit einem sich teilweise von der Oeffnung in den Innenraum des Probenröhrchens erstreckenden Einsteckteil, dessen Aussendurchmesser in seinem unteren, im wesentlichen zur Einführung in das Probenröhrchen bestimmten Teil dem Innendurchmesser des Probenröhrchens entspricht.The invention relates to a closure device for centrifuge sample tubes with an insertion part extending partially from the opening into the interior of the sample tube, the outer diameter of which corresponds in its lower part, which is essentially intended for insertion into the sample tube, to the inner diameter of the sample tube.
Herkömmliche Verschlussdeckel für Probenröhrchen, die in Festwinkelrotoren von Ultrazentrifugen zum Einsatz kommen, bestehen im allgemeinen aus einem Einsteckteil zur Einführung in die Oeffnung des Probenröhrchens und einer Spannvorrichtung, mit der der Rand des Probenröhrchens in der Verschlussvorrichtung eingespannt und auf diese Weise eine feste und dichte Verbindung zwischen dem Probenröhrchen und der Verschlussvorrichtung hergestellt wird. Der Einsteckteil ist in seinem unteren, zur Einführung in die Oeffnung des Probenröhrchens vorgesehenen Bereich zylindrisch, mit einem dem Innendurchmesser des Röhrchens entsprechenden Aussendurchmesser. Nach oben besitzt der zylindrische Teil einen dünneren Ansatz, der mit einem Gewinde versehen ist. Die Spannvorrichtung enthält in der Regel einen Deckel, der eine nach aussen oder innen geneigte konische Fläche aufweist und der mit einer zum Gewinde passenden Mutter mit dem Einsteckteil verschraubt wird. Durch die konische Fläche wird der Rand des Probenröhrchens entweder nach innen gegen eine entsprechende konische Fläche am oberen Rand des zylindrischen Bereichs des Einsteckteils oder mit Hilfe einer O-Ring-Dichtung nach aussen gegen einen entsprechenden zylindrischen Ansatz des Deckels gepresst.Conventional closure caps for sample tubes, which are used in fixed-angle rotors of ultracentrifuges, generally consist of an insertion part for insertion into the opening of the sample tube and a clamping device with which the edge of the sample tube is clamped in the closure device and in this way a firm and tight connection between the sample tube and the closure device. The insert part is in its lower, for insertion into the opening of the sample tube cylindrical area with an outer diameter corresponding to the inner diameter of the tube. At the top, the cylindrical part has a thinner shoulder, which is threaded. The clamping device usually contains a cover which has a conical surface which is inclined outwards or inwards and which is screwed to the plug-in part using a nut which matches the thread. Due to the conical surface, the edge of the sample tube is pressed either inwards against a corresponding conical surface at the upper edge of the cylindrical area of the plug-in part or with the help of an O-ring seal outwards against a corresponding cylindrical extension of the lid.
Diese herkömmlichen Verschlussvorrichtungen haben den Nachteil, dass sie durch die Zahl der Einzelteile, aus denen sie bestehen, verhältnismässig teuer sind. Ausserdem ergibt sich durch die notwendige Verschraubung eine relativ grosse Arbeitsintensität. Schliesslich ist es auch noch ungünstig, dass für die Verschraubung ein spezielles Werkzeug vorhanden sein muss.These conventional locking devices have the disadvantage that they are relatively expensive due to the number of individual parts from which they are made. In addition, the necessary screwing results in a relatively large amount of work. Finally, it is also unfavorable that a special tool must be available for the screw connection.
Das Ziel der vorliegenden Erfindung war eine vereinfachte Verschlussvorrichtung, die die Nachteile der bekannten Verschlussvorrichtungen nicht aufweist und dennoch die gleiche Sicherheit bietet, wie sie bei herkömmlichen-Vorrichtungen dieser Art für den Einsatz in Ultrazentrifugen notwendig ist.The aim of the present invention was a simplified closure device which does not have the disadvantages of the known closure devices and nevertheless offers the same safety as is necessary with conventional devices of this type for use in ultracentrifuges.
Erfindungsgemäss wird dies dadurch erreicht, dass der Aussendurchmesser des Einsteckteils in seinem oberen, im wesentlichen ausserhalb des Röhrchens befindlichen Teil grösser ist als der Innendurchmesser des Röhrchens und ausserhalb des Röhrchens ein Widerlager vorhanden ist, gegen das der Rand des Probenröhrchens vom Einsteckteil unter der Wirkung der Zentrifugalkraft gepresst wird.This is achieved according to the invention in that the outer diameter of the insert part in its upper part, which is essentially outside the tube, is larger than the inside diameter of the tube and outside the tube there is an abutment against which the edge of the sample tube from the insert part under the effect of the Centrifugal force is pressed.
Das Widerlager weist vorzugsweise eine konische oder ebene, zur Achse des Probenröhrchens konzentrische Ringfläche auf. In einer Ausführungsform der Erfindung kann das Widerlager aus einem von unten her über das Probenröhrchen zu schiebenden Ring bestehen. Nach einer anderen Ausführungsform kann das Widerlager im Rotor selbst ausgebildet sein.The abutment preferably has a conical or flat ring surface which is concentric with the axis of the sample tube. In one embodiment of the invention, the abutment can consist of a ring to be pushed from below over the sample tube. According to another embodiment, the abutment can be formed in the rotor itself.
Die üblicherweise aus Kunststoff bestehenden Probenröhrchen können entweder einen Oeffnungsrand ohne zusätzliche Verstärkung aufweisen, oder mit einer wulstartigen Verstärkung oder einer Art Flansch versehen sein. Falls am Rand des Probenröhrchens keine zusätzlichen Vorkehrungen getroffen sind, muss der Einsteckteil im oberen Bereich des in das Röhrchen einzuführenden Teils eine zusätzliche Verdickung aufweisen, durch die das Probenröhrchen aufgeweitet wird, damit an seinem Aussendurchmesser eine dem Widerlager entsprechende konische Fläche entsteht.The sample tubes usually made of plastic can either have an opening edge without additional reinforcement, or can be provided with a bead-like reinforcement or a type of flange. If no additional precautions are taken at the edge of the sample tube, the plug-in part must have an additional thickening in the upper area of the part to be inserted into the tube, by means of which the sample tube is expanded so that a conical surface corresponding to the abutment is created on its outer diameter.
Im Folgenden sind anhand der beiliegenden Zeichnungen Ausführungsformen der Erfindung beschrieben. In den Figuren ist folgendes gezeigt:
- Figur l: eine perspektivische Darstellung einer Ausführungsform der Verschlussvorrichtung nach der Erfindung, teilweise aufgeschnitten
- Figur 2a), b) und c): Teilquerschnitte einiger weiterer Ausführungsformen der Verschlussvorrichtung.
- Figure l: a perspective view of an embodiment of the closure device according to the invention, partially cut away
- Figure 2a), b) and c): partial cross sections of some other embodiments of the closure device.
Die in Figur 1 perspektivisch dargestellte Verschlussvorrichtung 1 ist an einem Probenröhrchen 2 angebracht und besteht aus einem Einsteckteil 3 und einem Spannring 4. Der Einsteckteil 3 besitzt einen zylindrischen unteren zur Einführung in das Probenröhrchen 2 vorgesehenen Teil 5, dessen Aussendurchmesser dem Innendurchmesser des Probenröhrchens 2 entspricht. Der ebenfalls zylindrische obere, ausserhalb des Probenröhrchens befindliche Teil 6 des Einsteckteils besitzt einen Durchmesser, der grösser ist als der Innendurchmesser des Probenröhrchens. Zwischen den beiden Bereichen ergibt sich ein Absatz 7, an dem der obere Rand des Probenröhrchens 2 ansteht.The
Unterhalb des Absatzes 7 besitzt der untere Teil 5 des Einsteckteils 3 einen Bereich 8, dessen Aussendurchmesser etwas grösser ist als der Innendurchmesser des Probenröhrchens 2, jedoch nur so gross, dass der Bereich 8 unter Aufweitung des Probenröhrchens noch in dasselbe eingeschoben werden kann. Zwischen dem verdickten Bereich 8 des unteren Teils 5 und einem dünneren Bereich befindet sich eine Uebergangszone 9, die konische Form besitzt.Below the
Wie aus dem Verlauf der Schnittfläche des Probenröhrchens in Figur 1 ersichtlich ist, nimmt das aufgesteckte Probenröhrchen 2 in seinem oberen Randbereich die Kontur der Uebergangszone 9 und des aufgeweiteten Bereichs 8 an.As can be seen from the course of the cut surface of the sample tube in FIG. 1, the attached
Der zweite Teil der Verschlussvorrichtung besteht aus dem Ring 4, der den Einsteckteil 3 und den oberen Rand des Probenröhrchens von aussen umgibt. Die innere Kontur des Rings 4 entspricht der Kontur des auf den Einsteckteil 3 geschobenen Probenröhrchens, d.h. die Innenfläche des Rings 4 ist von unten her zunächst - zylindrisch mit einem Durchmesser, der dem Aussendurchmesser des Probenröhrchens entspricht, sodann konisch und anschliessend wiederum zylindrisch mit einem Innendurchmesser, der dem Aussendurchmesser des oberen Teils 6 entspricht. Die genauen Durchmesser des konischen und der zylindrischen Bereiche des Einsteckteils 3 und des Rings 4 sind so aufeinander und auf die Wandstärke des Probenröhrchens 2 abgestimmt, dass das Probenröhrchen mit seinem oberen Rand durch das Zusammensetzen der Verschlussvorrichtung eingeklemmt wird.The second part of the closure device consists of the
Der Verschluss des Probenröhrchens mit dieser zweiteiligen Verschlussvorrichtung ist sehr einfach. Es wird lediglich der Einsteckteil 3 in die Oeffnung des Probenröhrchens eingeschoben, bis sein Rand an dem Absatz 7 ansteht. Sodann wird von unten her der Ring 4 über das Probenröhrchen 2 hochgeschoben, bis er festsitzt.Sealing the sample tube with this two-part sealing device is very easy. It will only the plug-in
Das so verschlossene Probenröhrchen wird in eine entsprechende Kammer eines Festwinkelrotors eingesetzt. Die Rotorkammer ist so ausgebildet, dass sie mit ihrem unteren Teil genau das Probenröhrchen 2 aufnimmt und dort, wo sich bei eingesetztem Probenröhrchen der untere Rand des Rings 4 befindet, einen Absatz aufweist, der den Ring 4 abstützt. Auf diese Weise bildet der konische Bereich der Innenwand des Rings 4 während des 2entrifugierens ein Widerlager, gegen das der Einsteckteil 3 mit seinem konischen Bereich 9 infolge der Zentrifugalkraft die entsprechende Wandzone des Probenröhrchens 2 anpresst. Dadurch wird die Verbindung zwischen der Verschlussvorrichtung und dem Probenröhrchen mit zunehmender Drehzahl der Zentrifuge infolge der zunehmenden Zentrifugalkraft immer besser.The sample tube sealed in this way is inserted into a corresponding chamber of a fixed-angle rotor. The rotor chamber is designed in such a way that it precisely receives the
Selbstverständlich sind neben der in Figur 1 gezeigten konischen Aufweitung auch andere Formgebungen der zusammenwirkenden Durchmesser von Einsteckteil und Ring sowie der Kontur des Randbereichs des Probenröhrchens möglich. Einige weitere Beispiele sind in den Figuren 2a) bis 2c) gezeigt.Of course, in addition to the conical widening shown in FIG. 1, other shapes of the interacting diameters of the insert part and the ring and the contour of the edge region of the sample tube are also possible. Some other examples are shown in Figures 2a) to 2c).
In der Ausführungsform gemäss Figur 2a) besitzt das Probenröhrchen 2 an seinem oberen Rand eine umlaufende Verdickung 10 mit einer konischen unteren Fläche. Da bei dieser Version die konische Fläche am Probenröhrchen bereits vorhanden ist, kann der Einsteckteil 3 einfacher gestaltet werden, indem auf die verdickte Zone 8 und den konischen Uebergangsbereich 9 verzichtet werden kann. Der Ring 4 weist jedoch wiederum eine entsprechende konische Innenfläche auf, gegen die der umlaufende Wulst 10 des Probenröhrchens durch die Zentrifugalkraft beim Zentrifugieren gepresst wird. In Figur 2a) ist auch ersichtlich, wie der Ring 4 mit seiner Unterseite auf dem Absatz 11 der Rotorkammer aufsitzt.In the embodiment according to FIG. 2a), the
Figur 2b) zeigt eine weiter vereinfachte Verschlussvorrichtung, die nur noch aus dem Einsteckteil 3 besteht. Dieser besitzt in seinem unteren Teil wiederum die verdickte Zone 8 und die konische Uebergangszone 9 der Version, die in Figur 1 gezeigt ist. Anstelle des Rings tritt bei dieser Ausführungsform jedoch eine entsprechende konische Fläche 12 der Wand der Rotorkammer. Durch die Zentrifugalkraft wird der konisch aufgeweitete Bereich des Probenröhrchens gegen diese konische Fläche 12 gepresst.Figure 2b) shows a further simplified closure device, which only consists of the plug-in
In Figur 2c) ist eine Ausführungsform gezeigt, bei der das Probenröhrchen an seinem oberen Rand einen umlaufenden Flansch 13 besitzt. Dieser Flansch, der bei der in Figur 2c) gezeigten Ausführungsform eben ist, liegt auf einer entsprechenden ebenen Fläche des Rings 4 auf und wird bei der Zentrifugierung gegen diese ebene Fläche des Rings gepresst. Bei dieser Version wie auch bei allen anderen Versionen könnte selbstverständlich ebenfalls auf den Ring 4 verzichtet werden, wenn die entsprechende Widerlagerfläche in der Rotorkammer selbst vorgesehen ist.FIG. 2 c) shows an embodiment in which the sample tube has a
Für die erfindungsgemässe Verschlussvorrichtung kommen die gleichen Materialien in Frage, wie sie für herkömmliche Verschlussvorrichtungen verwendet werden, also vorzugsweise Aluminium oder Titan.For the closure device according to the invention, the same materials come into question as are used for conventional closure devices, that is to say preferably aluminum or titanium.
Es ist sehr leicht einzusehen, dass die erfindungsgemässe Verschlussvorrichtung gegenüber den bekannten Verschlussvorrichtungen wesentlich vereinfacht ist. So besteht sie nur aus zwei Teilen, bei einigen Ausführungsformen sogar nur aus einem einzigen Teil. Vor allem aber ist die Handhabung extrem vereinfacht. Das Einstecken und gegebenenfalls das Aufschieben des Rings sind Arbeitsgänge, die in der Grössenordnung von Sekunden durchgeführt werden können. Demgegenüber war das Anbringen einer Verschlussvorrichtung der bekannten Art ein Arbeitsgang der mindestens den zehnfachen Zeitaufwand erforderte.It is very easy to see that the closure device according to the invention is considerably simplified compared to the known closure devices. So it consists of only two parts, in some embodiments even only one part. Above all, handling is extremely simplified. The plugging and, if necessary, the opening of the ring are operations which can be carried out in the order of seconds. In contrast, the attachment of a closure device of the known type was a work step that required at least ten times the time.
Claims (7)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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CH30580 | 1980-01-15 | ||
CH305/80 | 1980-01-15 |
Publications (2)
Publication Number | Publication Date |
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EP0032544A1 true EP0032544A1 (en) | 1981-07-29 |
EP0032544B1 EP0032544B1 (en) | 1984-07-25 |
Family
ID=4183971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP80107484A Expired EP0032544B1 (en) | 1980-01-15 | 1980-11-29 | Fixed angle rotor for ultra centrifuge |
Country Status (4)
Country | Link |
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US (1) | US4396381A (en) |
EP (1) | EP0032544B1 (en) |
JP (2) | JPS56105767A (en) |
DE (1) | DE3068734D1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2118155A (en) * | 1982-04-15 | 1983-10-26 | Fisons Plc | Centrifuge tube sealing assembly |
EP0181550A2 (en) * | 1984-10-30 | 1986-05-21 | E.I. Du Pont De Nemours And Company | Crimpable capping assembly for a centrifuge tube |
EP0341342A2 (en) * | 1988-05-09 | 1989-11-15 | Multi-Technology, Inc. | Fail safe releasable locks for capped disposable centrifuge containers |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59138463U (en) * | 1983-03-04 | 1984-09-14 | 日立工機株式会社 | Crimp lid for centrifuge tube |
US4778074A (en) * | 1987-07-08 | 1988-10-18 | Honeywell Inc. | Composite material and metal canister |
US4896780A (en) * | 1988-05-09 | 1990-01-30 | Multi-Technology Inc. | Fail safe releasible locks for capped disposable centrifuge containers |
US4874102A (en) * | 1988-05-09 | 1989-10-17 | Multi-Technology Inc. | Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like |
US4956103A (en) * | 1988-05-09 | 1990-09-11 | Multi-Technology Inc. | Fail safe releasible locks for capped disposable centrifuge containers |
US4953741A (en) * | 1988-05-09 | 1990-09-04 | Multi-Technology Inc. | Medical fail safe releasible locks and/or seals for capped disposable centrifuge containers, cryogenic vials and the like |
US4902270A (en) * | 1988-10-03 | 1990-02-20 | Nalge Company | Centrifuge tube |
US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
JP4761254B2 (en) * | 2005-06-09 | 2011-08-31 | 日立工機株式会社 | Sample container with sealing mechanism for centrifuge and centrifuge using the same |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3800947A (en) * | 1971-07-16 | 1974-04-02 | P Smith | Reagent tube and centrifugally operated solid-liquid separating device |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3508653A (en) * | 1967-11-17 | 1970-04-28 | Charles M Coleman | Method and apparatus for fluid handling and separation |
US4190196A (en) * | 1975-04-29 | 1980-02-26 | E. I. Du Pont De Nemours And Company | Centrifuge tube cap |
US3998383A (en) * | 1975-07-16 | 1976-12-21 | E. I. Du Pont De Nemours And Company | Gradient separation apparatus |
US4087043A (en) * | 1976-08-17 | 1978-05-02 | Beckman Instruments, Inc. | Dual seal arrangement for a centrifuge rotor tube cavity |
US4114803A (en) * | 1976-12-17 | 1978-09-19 | E. I. Du Pont De Nemours And Company | Centrifuge tube enclosure |
US4102490A (en) * | 1977-06-06 | 1978-07-25 | Beckman Instruments, Inc. | Data ring for vertical tube rotor |
US4166573A (en) * | 1977-12-01 | 1979-09-04 | E. I. Du Pont De Nemours And Company | Centrifuge tube enclosure |
FR2439622A1 (en) * | 1978-10-28 | 1980-05-23 | Fisons Ltd | Test tube container for centrifuge - with union nut and screwed cap for sealed enclosure |
US4222513A (en) * | 1978-12-12 | 1980-09-16 | E. I. Du Pont De Nemours And Company | Centrifuge tube seal |
-
1980
- 1980-11-29 EP EP80107484A patent/EP0032544B1/en not_active Expired
- 1980-11-29 DE DE8080107484T patent/DE3068734D1/en not_active Expired
-
1981
- 1981-01-06 US US06/222,928 patent/US4396381A/en not_active Expired - Lifetime
- 1981-01-14 JP JP456581A patent/JPS56105767A/en active Pending
-
1982
- 1982-11-29 JP JP1982180531U patent/JPS58112452U/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3800947A (en) * | 1971-07-16 | 1974-04-02 | P Smith | Reagent tube and centrifugally operated solid-liquid separating device |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2118155A (en) * | 1982-04-15 | 1983-10-26 | Fisons Plc | Centrifuge tube sealing assembly |
EP0181550A2 (en) * | 1984-10-30 | 1986-05-21 | E.I. Du Pont De Nemours And Company | Crimpable capping assembly for a centrifuge tube |
EP0181550A3 (en) * | 1984-10-30 | 1987-10-07 | E.I. Du Pont De Nemours And Company | Crimpable capping assembly for a centrifuge tube |
EP0341342A2 (en) * | 1988-05-09 | 1989-11-15 | Multi-Technology, Inc. | Fail safe releasable locks for capped disposable centrifuge containers |
EP0341342A3 (en) * | 1988-05-09 | 1990-09-12 | Multi-Technology, Inc. | Fail safe releasable locks for capped disposable centrifuge containers |
Also Published As
Publication number | Publication date |
---|---|
EP0032544B1 (en) | 1984-07-25 |
JPS58112452U (en) | 1983-08-01 |
JPS56105767A (en) | 1981-08-22 |
US4396381A (en) | 1983-08-02 |
DE3068734D1 (en) | 1984-08-30 |
JPS613469Y2 (en) | 1986-02-03 |
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