EG14354A - Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants - Google Patents

Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants

Info

Publication number: EG14354A
Authority: EG; Egypt
Prior art keywords: useful; inflammatory conditions; preparing novel; relieving inflammatory; aminothiazoles
Prior art date: 1978-06-02

Application number

EG333/79A

Inventor

George Joseph

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-02

Filing date

1979-05-30

Publication date

1984-06-30

1979-05-30 Application filed by Pfizer filed Critical Pfizer

1984-06-30 Application granted granted Critical

1984-06-30 Publication of EG14354A publication Critical patent/EG14354A/en

Links

RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title 1
230000004968 inflammatory condition Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B15/00—Nails; Staples
- F16B15/0023—Nail plates
- F16B2015/0076—Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EG333/79A 1978-06-02 1979-05-30 Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants EG14354A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US91183078A	1978-06-02	1978-06-02

Publications (1)

Publication Number	Publication Date
EG14354A true EG14354A (en)	1984-06-30

Family

ID=25430923

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG333/79A EG14354A (en)	1978-06-02	1979-05-30	Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants

Country Status (36)

Country	Link
JP (1)	JPS5936988B2 (en)
AR (1)	AR226285A1 (en)
AT (1)	AT373248B (en)
AU (1)	AU511242B2 (en)
BE (1)	BE876732A (en)
CA (1)	CA1117949A (en)
CH (1)	CH639653A5 (en)
CS (1)	CS216927B2 (en)
DD (1)	DD144055A5 (en)
DE (1)	DE2922523C2 (en)
DK (1)	DK150068C (en)
EG (1)	EG14354A (en)
ES (1)	ES481220A1 (en)
FI (1)	FI68820C (en)
FR (1)	FR2427333A1 (en)
GB (1)	GB2022085B (en)
GR (1)	GR73142B (en)
HK (1)	HK66487A (en)
HU (1)	HU180045B (en)
IE (1)	IE48426B1 (en)
IL (1)	IL57450A (en)
IT (1)	IT1121238B (en)
KE (1)	KE3459A (en)
LU (1)	LU81349A1 (en)
MY (1)	MY8500318A (en)
NL (1)	NL178421C (en)
NO (1)	NO150760C (en)
NZ (1)	NZ190623A (en)
PH (1)	PH17020A (en)
PL (1)	PL117515B1 (en)
PT (1)	PT69718A (en)
SE (1)	SE438333B (en)
SG (1)	SG56184G (en)
SU (1)	SU843746A3 (en)
YU (1)	YU40997B (en)
ZA (1)	ZA792729B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0063575A4 (en) *	1980-10-24	1983-02-14	Ronald Peter Hansen	Dust mitigation system.
WO1982002384A1 (en) *	1981-01-08	1982-07-22	Sakano Isao	Their preparation,and medicinal composition containing same
JPS57136579A (en) *	1981-01-21	1982-08-23	Mitsui Toatsu Chem Inc	Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS57116067A (en) *	1981-01-12	1982-07-19	Sankyo Kagaku Kk	Novel 8-quinolinesulfonyl derivative, its synthesis and use
DE3273781D1 (en) *	1981-01-13	1986-11-20	Mitsui Toatsu Chemicals	Novel thiazole compounds, process for their preparation, and medicinal composition containing same
WO1982002386A1 (en) *	1981-01-13	1982-07-22	Sakano Isao	Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
JPS57154175A (en) *	1981-03-16	1982-09-22	Mitsui Toatsu Chem Inc	2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (en) *	1982-07-22	1984-01-26	Basf Ag, 6700 Ludwigshafen	METHOD FOR PRODUCING 2-N, N-DISUBSTITUTED AMINOTHIAZOLES
WO1986003203A1 (en) *	1984-11-22	1986-06-05	Yoshitomi Pharmaceutical Industries, Ltd.	Thienylthiazole derivatives
FR2581063B1 (en) *	1985-04-30	1987-07-17	Chauvin Blache Lab	AMINO-2 THIAZOLES N-SUBSTITUTED, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
JPS63152368A (en) *	1986-06-03	1988-06-24	Sumitomo Pharmaceut Co Ltd	Novel aminoazole derivative and acid addition salt thereof
JPH075579B2 (en) *	1986-09-01	1995-01-25	吉富製薬株式会社	Aminothiazole compound
JPH0753666B2 (en) *	1987-09-14	1995-06-07	久光製薬株式会社	Anti-inflammatory agent consisting of substituted diphenylthiazole derivative
DE69031624T2 (en) *	1989-08-10	1998-05-14	Commw Scient Ind Res Org	METHOD FOR PRODUCING AN ELECTROSUSPENSION OF MICROPARTICLES
DE69132293D1 (en) *	1991-03-07	2000-08-10	Hisamitsu Pharmaceutical Co	DIPHENYLTHIAZOLE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY
FR2692893B1 (en) *	1992-06-24	1994-09-02	Sanofi Elf	Branched alkylamino thiazole derivatives, processes for their preparation and pharmaceutical compositions containing them.
WO1996003392A1 (en) *	1994-07-27	1996-02-08	G.D. Searle & Co.	Substituted thiazoles for the treatment of inflammation
FR2754258B1 (en)	1996-10-08	1998-12-31	Sanofi Sa	AMINOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2001064674A1 (en)	2000-03-01	2001-09-07	Janssen Pharmaceutica N.V.	2,4-disubstituted thiazolyl derivatives
EP1423113A4 (en) *	2001-08-13	2007-04-18	Phenex Pharmaceuticals Ag	Nr1h4 nuclear receptor binding compounds
WO2003027095A1 (en) *	2001-09-26	2003-04-03	Bayer Pharmaceuticals Corporation	Substituted 3-pyridyl tetrazoles as steroid c17,20 lyase inhibitors
BR0306811A (en)	2002-01-11	2004-10-26	Sankyo Co	Compound, pharmacologically acceptable ester thereof, pharmaceutical composition and methods for the prevention or treatment of autoimmune diseases, rheumatoid arthritis and rejection caused by the transplantation of various organs in a mammal
EP1555264A1 (en) *	2004-01-15	2005-07-20	Sireen AG	Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
AU2005215320B2 (en)	2004-02-24	2008-04-17	Sankyo Company, Limited	Amino alcohol compound
AU2006244203B2 (en) *	2005-05-09	2012-05-03	Achillion Pharmaceuticals, Inc.	Thiazole compounds and methods of use
CA2636077C (en)	2006-01-18	2012-01-03	Amgen Inc.	Thiazole compounds as protein kinase b (pkb) inhibitors
CA2692713A1 (en)	2007-07-17	2009-01-22	Amgen Inc.	Heterocyclic modulators of pkb
CA2693473A1 (en)	2007-07-17	2009-01-22	Amgen Inc.	Thiadiazole modulators of pkb
WO2012170951A2 (en) *	2011-06-10	2012-12-13	Calcimedica, Inc.	Compounds that modulate intracellular calcium
US20120316182A1 (en)	2011-06-10	2012-12-13	Calcimedica, Inc.	Compounds that modulate intracellular calcium
WO2013059677A1 (en)	2011-10-19	2013-04-25	Calcimedica, Inc.	Compounds that modulate intracellular calcium
CN110590785B (en) *	2019-09-23	2021-02-02	武汉大学	Aminothiazole compound, preparation method thereof and application of aminothiazole compound in resisting enterovirus 71

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3458526A (en) *	1966-09-26	1969-07-29	Upjohn Co	Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

1979
- 1979-04-30 DK DK177679A patent/DK150068C/en not_active IP Right Cessation
- 1979-05-23 GB GB7917872A patent/GB2022085B/en not_active Expired
- 1979-05-29 CH CH501679A patent/CH639653A5/en not_active IP Right Cessation
- 1979-05-30 CS CS793728A patent/CS216927B2/en unknown
- 1979-05-30 EG EG333/79A patent/EG14354A/en active
- 1979-05-31 SE SE7904798A patent/SE438333B/en not_active IP Right Cessation
- 1979-05-31 CA CA000328805A patent/CA1117949A/en not_active Expired
- 1979-05-31 YU YU1288/79A patent/YU40997B/en unknown
- 1979-05-31 LU LU81349A patent/LU81349A1/en unknown
- 1979-05-31 PH PH22588A patent/PH17020A/en unknown
- 1979-05-31 SU SU792773929A patent/SU843746A3/en active
- 1979-05-31 HU HU79PI679A patent/HU180045B/en not_active IP Right Cessation
- 1979-05-31 AU AU47634/79A patent/AU511242B2/en not_active Ceased
- 1979-05-31 IL IL57450A patent/IL57450A/en unknown
- 1979-06-01 AT AT0401679A patent/AT373248B/en not_active IP Right Cessation
- 1979-06-01 IT IT23228/79A patent/IT1121238B/en active
- 1979-06-01 NL NLAANVRAGE7904337,A patent/NL178421C/en not_active IP Right Cessation
- 1979-06-01 ZA ZA792729A patent/ZA792729B/en unknown
- 1979-06-01 JP JP54068781A patent/JPS5936988B2/en not_active Expired
- 1979-06-01 DD DD79213371A patent/DD144055A5/en not_active IP Right Cessation
- 1979-06-01 FR FR7914164A patent/FR2427333A1/en active Granted
- 1979-06-01 GR GR59240A patent/GR73142B/el unknown
- 1979-06-01 PL PL1979216030A patent/PL117515B1/en unknown
- 1979-06-01 ES ES481220A patent/ES481220A1/en not_active Expired
- 1979-06-01 FI FI791754A patent/FI68820C/en not_active IP Right Cessation
- 1979-06-01 AR AR276782A patent/AR226285A1/en active
- 1979-06-01 BE BE0/195534A patent/BE876732A/en not_active IP Right Cessation
- 1979-06-01 NZ NZ190623A patent/NZ190623A/en unknown
- 1979-06-01 DE DE2922523A patent/DE2922523C2/en not_active Expired
- 1979-06-01 PT PT69718A patent/PT69718A/en unknown
- 1979-06-01 NO NO791831A patent/NO150760C/en unknown
- 1979-08-08 IE IE1069/79A patent/IE48426B1/en unknown
1984
- 1984-08-13 SG SG561/84A patent/SG56184G/en unknown
- 1984-09-24 KE KE3459A patent/KE3459A/en unknown
1985
- 1985-12-30 MY MY318/85A patent/MY8500318A/en unknown
1987
- 1987-09-17 HK HK664/87A patent/HK66487A/en unknown

Also Published As

Publication number	Publication date
CA1117949A (en)	1982-02-09
IE791069L (en)	1979-12-02
HK66487A (en)	1987-09-25
FR2427333B1 (en)	1983-05-20
NO791831L (en)	1979-12-04
IL57450A (en)	1982-11-30
DK150068C (en)	1987-06-29
AU4763479A (en)	1979-12-06
DD144055A5 (en)	1980-09-24
NL178421C (en)	1986-03-17
NO150760C (en)	1984-12-12
JPS54160369A (en)	1979-12-19
BE876732A (en)	1979-12-03
GB2022085B (en)	1983-01-12
IE48426B1 (en)	1985-01-23
PH17020A (en)	1984-05-11
DK150068B (en)	1986-12-01
GB2022085A (en)	1979-12-12
LU81349A1 (en)	1979-12-07
IT7923228A0 (en)	1979-06-01
JPS5936988B2 (en)	1984-09-06
HU180045B (en)	1983-01-28
SE7904798L (en)	1979-12-03
DE2922523A1 (en)	1979-12-06
SG56184G (en)	1985-03-08
AU511242B2 (en)	1980-08-07
IL57450A0 (en)	1979-09-30
SU843746A3 (en)	1981-06-30
SE438333B (en)	1985-04-15
NO150760B (en)	1984-09-03
ZA792729B (en)	1981-03-25
YU128879A (en)	1982-10-31
MY8500318A (en)	1985-12-31
GR73142B (en)	1984-02-09
FR2427333A1 (en)	1979-12-28
AT373248B (en)	1983-12-27
FI68820C (en)	1985-11-11
IT1121238B (en)	1986-03-26
AR226285A1 (en)	1982-06-30
FI68820B (en)	1985-07-31
DE2922523C2 (en)	1982-10-21
FI791754A (en)	1979-11-26
ATA401679A (en)	1983-05-15
YU40997B (en)	1986-10-31
PL117515B1 (en)	1981-08-31
PT69718A (en)	1979-07-01
NL7904337A (en)	1979-12-04
PL216030A1 (en)	1980-03-10
KE3459A (en)	1984-10-12
CH639653A5 (en)	1983-11-30
DK177679A (en)	1979-12-03
NL178421B (en)	1985-10-16
ES481220A1 (en)	1980-09-01
CS216927B2 (en)	1982-12-31
NZ190623A (en)	1984-07-06

Publication	Publication Date	Title
EG14354A (en)	1984-06-30	Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants
GB2017682B (en)	1982-08-25	Process for the preparation of aliphatic amines
DE2964427D1 (en)	1983-02-03	Process for the preparation of furanyl-benzazoles
DE2966723D1 (en)	1984-04-05	Process for the preparation of 6-amino-6-desoxy-l-sorbose
DE2960539D1 (en)	1981-10-29	Process for the preparation of 4-fluor-3-phenoxytoluene
DE2962201D1 (en)	1982-03-25	Process for the preparation of amines
IL57539A0 (en)	1979-10-31	Process for the preparation of 0-methoallyl-oxyphenol
DE2962321D1 (en)	1982-04-29	Process for the preparation of shaped articles
DE2964389D1 (en)	1983-01-27	Process for the preparation of 2-imidazolines
DE2963068D1 (en)	1982-07-29	Process for the preparation of benzothiazole-disulphide
DE2961140D1 (en)	1981-12-10	Process for the preparation of azaspirodecanes
DE2961237D1 (en)	1982-01-14	Process for the preparation of hydroxyalkyl-perfluoralkane-sulfonamides
ZA791589B (en)	1980-04-30	Process for the preparation of 2-mercaptobenzthiazole
DE2960104D1 (en)	1981-02-26	Process for the preparation of thiazole derivatives
DE2960278D1 (en)	1981-07-30	Process for the preparation of 4-acyloxy-2-methylcrotonaldehydes
CY1242A (en)	1984-06-29	Process for the preparation of 1-n-acylaminoglycosides
DE2962108D1 (en)	1982-03-18	Process for the preparation of 4-methyl-2-amino-benzothiazole
GB2015998B (en)	1982-07-14	Process for the preparation of p-amino-diphenylamine
DE2960541D1 (en)	1981-10-29	Process for the preparation of 3-phenoxybenzaldehydes
DE2860555D1 (en)	1981-04-16	Process for the preparation of 4-methyl-5-chloromethyl-imidazole
DE2961888D1 (en)	1982-03-04	Process for the preparation of 6-hydroxypyrid-2-ones
GB2088852B (en)	1982-11-24	Process for the preparation of 9-oxobenzomorphans
DE2964895D1 (en)	1983-03-31	Process for the preparation of isopropylamino-2-pyrimidine
GB2018774B (en)	1982-12-01	Process for the preparation of 2-mercaptobenzthiazole
DE2961975D1 (en)	1982-03-11	Process for the preparation of 5-diethylamino-2-pentanol