EE9900315A - Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena - Google Patents

Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena

Info

Publication number: EE9900315A
Authority: EE; Estonia
Prior art keywords: pct; pyrrolo; medicaments; sec; pyrimidinone derivatives
Prior art date: 1996-12-21

Application number

EEP199900315A

Other languages

English (en)

Estonian (et)

Inventor

Cooper Martin

Cheshire David

Donald David

Furber Mark

Perry Matthew

Harrison Richard

Tomkinson Nicholas

Original Assignee

Astra Pharmaceuticals Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-21

Filing date

1997-12-18

Publication date

2000-02-15

1997-12-18 Application filed by Astra Pharmaceuticals Limited filed Critical Astra Pharmaceuticals Limited

2000-02-15 Publication of EE9900315A publication Critical patent/EE9900315A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Transplantation (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EEP199900315A 1996-12-21 1997-12-18 Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena EE9900315A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9626643.2A GB9626643D0 (en)	1996-12-21	1996-12-21	Compounds
PCT/SE1997/002157 WO1998028301A1 (en)	1996-12-21	1997-12-18	Pyrrolo[3,4-d]pyrimidinone derivatives and their use as medicaments

Publications (1)

Publication Number	Publication Date
EE9900315A true EE9900315A (et)	2000-02-15

Family

ID=10804862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900315A EE9900315A (et)	1996-12-21	1997-12-18	Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena

Country Status (23)

Country	Link
US (8)	US6046204A (id)
EP (1)	EP0946562B1 (id)
JP (1)	JP2001507687A (id)
KR (1)	KR20000069605A (id)
CN (1)	CN1246119A (id)
AT (1)	ATE215088T1 (id)
AU (1)	AU717429B2 (id)
BR (1)	BR9714063A (id)
CA (1)	CA2275312A1 (id)
CZ (1)	CZ289925B6 (id)
DE (1)	DE69711430T2 (id)
EE (1)	EE9900315A (id)
GB (1)	GB9626643D0 (id)
HU (1)	HUP0002839A3 (id)
ID (1)	ID21682A (id)
IL (1)	IL130538A0 (id)
IS (1)	IS5082A (id)
NO (1)	NO993027L (id)
NZ (1)	NZ336124A (id)
PL (1)	PL334228A1 (id)
SK (1)	SK76699A3 (id)
TR (1)	TR199901433T2 (id)
WO (1)	WO1998028301A1 (id)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9801399D0 (sv)	1998-04-21	1998-04-21	Astra Pharma Prod	Method and apparatus for filling containers
ATE356810T1 (de)	1999-01-15	2007-04-15	Altana Pharma Ag	Polysubstituted 6-phenylphenanthridines mit pde- iv hemmender wirkung
WO2000042034A1 (en)	1999-01-15	2000-07-20	Byk Gulden	Phenanthridine-n-oxides with pde-iv inhibiting activity
AU2107700A (en)	1999-01-15	2000-08-01	Byk Gulden Lomberg Chemische Fabrik Gmbh	Phenanthridine-n-oxides with pde-iv inhibiting activity
US6361486B1 (en) *	2000-02-29	2002-03-26	Agilent Technologies, Inc.	Coaxial-drive centrifuge providing tilt control relative to centrifugal force
AU2001281255B2 (en) *	2000-08-14	2006-07-20	Ortho-Mcneil Pharmaceutical, Inc.	Substituted pyrazoles
US20070105841A1 (en) *	2000-08-14	2007-05-10	Breitenbucher J G	Method for treating allergies using substituted pyrazoles
TW200407315A (en) *	2002-04-23	2004-05-16	Sankyo Co	Pyrimidine derivatives
CA2533534C (en) *	2003-07-24	2013-03-19	Tecomet, Inc.	Assembled non-random foams
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
MY140748A (en)	2004-12-06	2010-01-15	Astrazeneca Ab	Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
US8198288B2 (en)	2006-05-04	2012-06-12	Pulmagen Therapeutics (Inflammation) Limited	Tetrahydropyrrolopyrimidinediones and their use in therapy
PT2024367E (pt)	2006-05-04	2010-12-03	Pulmagen Therapeutics Inflammation Ltd	Tetra-hidropirrolopirimidinadionas e a sua utilização a título de inibidores da elastase de neutrófilos humana
MX2008015489A (es)	2006-06-06	2009-01-13	Intra Cellular Therapies Inc	Compuestos organicos.
ES2588238T3 (es)	2007-12-06	2016-10-31	Intra-Cellular Therapies, Inc.	Derivados de pirazolopirimidin-4,6-diona y su uso como producto farmacéutico
WO2009100403A1 (en) *	2008-02-07	2009-08-13	Neurogen Corporation	Substituted aryl pyrimidinones
MA32939B1 (fr) *	2008-12-06	2012-01-02	Intra Cellular Therapies Inc	Composes organiques
US8859564B2 (en)	2008-12-06	2014-10-14	Intra-Cellular Therapies, Inc.	Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione derivatives useful as inhibitors of phosphodiesterase 1
AU2009322905A1 (en)	2008-12-06	2010-06-10	Intra-Cellular Therapies, Inc.	Organic compounds
IN2012DN00719A (id)	2009-08-10	2015-06-19	Univ California
US9371327B2 (en)	2010-05-31	2016-06-21	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
JP5879336B2 (ja)	2010-05-31	2016-03-08	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	有機化合物
US9062073B2 (en)	2011-05-27	2015-06-23	The Regents Of The University Of California	Pyrimido-pyrrolo-oxazine-dione compound inhibitors of the cystic fibrosis transmembrane conductance regulator protein and uses therefor
US9546175B2 (en)	2014-08-07	2017-01-17	Intra-Cellular Therapies, Inc.	Organic compounds
CN108129486B (zh) *	2018-01-25	2020-06-05	华东理工大学	嘧啶酮衍生物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993004047A1 (en) *	1991-08-16	1993-03-04	Merck & Co., Inc.	Quinazoline derivatives as inhibitors of hiv reverse transcriptase
GB9424842D0 (en) *	1994-12-09	1995-02-08	British Tech Group	Pharmaceutical compositions

1996
- 1996-12-21 GB GBGB9626643.2A patent/GB9626643D0/en active Pending
1997
- 1997-12-18 IL IL13053897A patent/IL130538A0/xx unknown
- 1997-12-18 CZ CZ19992204A patent/CZ289925B6/cs not_active IP Right Cessation
- 1997-12-18 KR KR1019997005595A patent/KR20000069605A/ko not_active Application Discontinuation
- 1997-12-18 EP EP97952146A patent/EP0946562B1/en not_active Expired - Lifetime
- 1997-12-18 PL PL97334228A patent/PL334228A1/xx unknown
- 1997-12-18 WO PCT/SE1997/002157 patent/WO1998028301A1/en not_active Application Discontinuation
- 1997-12-18 SK SK766-99A patent/SK76699A3/sk unknown
- 1997-12-18 TR TR1999/01433T patent/TR199901433T2/xx unknown
- 1997-12-18 HU HU0002839A patent/HUP0002839A3/hu unknown
- 1997-12-18 DE DE69711430T patent/DE69711430T2/de not_active Expired - Fee Related
- 1997-12-18 JP JP52869798A patent/JP2001507687A/ja not_active Ceased
- 1997-12-18 EE EEP199900315A patent/EE9900315A/xx unknown
- 1997-12-18 BR BR9714063-5A patent/BR9714063A/pt not_active IP Right Cessation
- 1997-12-18 AU AU55809/98A patent/AU717429B2/en not_active Ceased
- 1997-12-18 AT AT97952146T patent/ATE215088T1/de active
- 1997-12-18 CA CA002275312A patent/CA2275312A1/en not_active Abandoned
- 1997-12-18 NZ NZ336124A patent/NZ336124A/en unknown
- 1997-12-18 CN CN97181811A patent/CN1246119A/zh active Pending
- 1997-12-18 US US09/011,780 patent/US6046204A/en not_active Expired - Fee Related
- 1997-12-18 ID IDW990507A patent/ID21682A/id unknown
1999
- 1999-06-14 IS IS5082A patent/IS5082A/is unknown
- 1999-06-18 NO NO993027A patent/NO993027L/no not_active Application Discontinuation
2000
- 2000-02-17 US US09/506,090 patent/US6166206A/en not_active Expired - Fee Related
- 2000-02-17 US US09/505,857 patent/US6136974A/en not_active Expired - Fee Related
- 2000-02-17 US US09/506,091 patent/US6229013B1/en not_active Expired - Fee Related
- 2000-02-17 US US09/505,862 patent/US6211368B1/en not_active Expired - Fee Related
- 2000-11-08 US US09/707,880 patent/US6306863B1/en not_active Expired - Fee Related
2001
- 2001-10-09 US US09/971,709 patent/US20020025966A1/en not_active Abandoned
2003
- 2003-03-05 US US10/378,913 patent/US20030162798A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US6229013B1 (en)	2001-05-08
IS5082A (is)	1999-06-14
DE69711430T2 (de)	2002-10-31
HUP0002839A3 (en)	2001-04-28
CA2275312A1 (en)	1998-07-02
ID21682A (id)	1999-07-08
NO993027L (no)	1999-08-20
GB9626643D0 (en)	1997-02-12
BR9714063A (pt)	2002-01-02
EP0946562B1 (en)	2002-03-27
PL334228A1 (en)	2000-02-14
KR20000069605A (ko)	2000-11-25
CZ289925B6 (cs)	2002-04-17
CN1246119A (zh)	2000-03-01
SK76699A3 (en)	2000-05-16
AU5580998A (en)	1998-07-17
US6136974A (en)	2000-10-24
US6166206A (en)	2000-12-26
DE69711430D1 (de)	2002-05-02
HUP0002839A2 (hu)	2001-02-28
US6046204A (en)	2000-04-04
NO993027D0 (no)	1999-06-18
US20020025966A1 (en)	2002-02-28
WO1998028301A1 (en)	1998-07-02
AU717429B2 (en)	2000-03-23
US20030162798A1 (en)	2003-08-28
ATE215088T1 (de)	2002-04-15
IL130538A0 (en)	2000-06-01
US6211368B1 (en)	2001-04-03
NZ336124A (en)	2001-03-30
CZ220499A3 (cs)	2000-02-16
EP0946562A1 (en)	1999-10-06
JP2001507687A (ja)	2001-06-12
US6306863B1 (en)	2001-10-23
TR199901433T2 (xx)	1999-09-21

Publication	Publication Date	Title
EE9900315A (et)	2000-02-15	Pürrolo[3,4-d]pürimidinooni derivaadid ja nende kasutamine ravimitena
SE9701398D0 (sv)	1997-04-15	Novel compounds
EE200000318A (et)	2001-08-15	Uudsed ühendid
SE9702772D0 (sv)	1997-07-22	Novel compounds
TR200000197T2 (tr)	2000-06-21	Yeni bileşimler
BR9609617B1 (pt)	2010-07-27	derivados de 7h-pirrol[2,3-d]pirimidina, e composição farmacêutica.
HUT70505A (en)	1995-10-30	Pyrrolo[2,3-d]pyrimidine derivatives, pharmaceutical compositions containing them and process for preparing them
EE04018B1 (et)	2003-04-15	Tieno[2,3-d]pürimidiindioonid, nende valmistamisemeetod ja neid sisaldavad ravimkoostised
ATE251162T1 (de)	2003-10-15	Triazolo(4,5-d)pyrimidin-verbindungen
DE69804766D1 (de)	2002-05-16	Isoflavonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
AU1929688A (en)	1989-01-27	Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors