EE9800163A - New quinoxalinedione derivatives, their preparation and use as medicaments - Google Patents

New quinoxalinedione derivatives, their preparation and use as medicaments

Info

Publication number
EE9800163A
EE9800163A EE9800163A EE9800163A EE9800163A EE 9800163 A EE9800163 A EE 9800163A EE 9800163 A EE9800163 A EE 9800163A EE 9800163 A EE9800163 A EE 9800163A EE 9800163 A EE9800163 A EE 9800163A
Authority
EE
Estonia
Prior art keywords
medicaments
preparation
new
quinoxalinedione derivatives
quinoxalinedione
Prior art date
Application number
EE9800163A
Other languages
Estonian (et)
Inventor
Huth Andreas
Krger Martin
Ottow Eckhard
Seidelmann Dieter
Neuhaus Roland
Schneider Herbert
Turski Lechoslaw
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of EE9800163A publication Critical patent/EE9800163A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EE9800163A 1995-11-24 1996-11-15 New quinoxalinedione derivatives, their preparation and use as medicaments EE9800163A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19545251A DE19545251A1 (en) 1995-11-24 1995-11-24 New quinoxalinedione derivatives, their production and use in pharmaceuticals
PCT/DE1996/002227 WO1997019066A1 (en) 1995-11-24 1996-11-15 New quinoxalindione derivatives, their preparation and use in medicaments

Publications (1)

Publication Number Publication Date
EE9800163A true EE9800163A (en) 1998-12-15

Family

ID=7779176

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800163A EE9800163A (en) 1995-11-24 1996-11-15 New quinoxalinedione derivatives, their preparation and use as medicaments

Country Status (20)

Country Link
EP (1) EP0876357A1 (en)
JP (1) JP2000500471A (en)
KR (1) KR19990071596A (en)
CN (1) CN1202891A (en)
AU (1) AU720083B2 (en)
CA (1) CA2238023A1 (en)
CZ (1) CZ160498A3 (en)
DE (1) DE19545251A1 (en)
EE (1) EE9800163A (en)
HU (1) HUP9902041A3 (en)
IL (1) IL124534A0 (en)
IS (1) IS4740A (en)
MX (1) MX9804068A (en)
NO (1) NO982349L (en)
NZ (1) NZ330492A (en)
PL (1) PL326844A1 (en)
SK (1) SK68298A3 (en)
TR (1) TR199800904T2 (en)
WO (1) WO1997019066A1 (en)
ZA (1) ZA969832B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737446A1 (en) * 1997-08-22 1999-02-25 Schering Ag Preparation of phosphonic acid derivatives
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN106619953A (en) * 2016-10-31 2017-05-10 山东省海盟生化科技有限公司 External traditional Chinese medicine composition for skin diseases, method for preparing external traditional Chinese medicine composition and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (en) * 1987-11-10 1996-10-30 Novo Nordisk As Analogous Process for Preparing Therapeutically Effective Quinoxaline Compounds
DK69790D0 (en) * 1990-03-16 1990-03-16 Novo Nordisk As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION OF USE
PT101004B (en) * 1991-10-26 1999-10-29 Schering Ag QUINOXALINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4439492A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE4439493A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE19519979A1 (en) * 1995-05-24 1996-11-28 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals

Also Published As

Publication number Publication date
SK68298A3 (en) 1998-12-02
NO982349L (en) 1998-07-01
AU1867497A (en) 1997-06-11
IS4740A (en) 1998-05-13
CA2238023A1 (en) 1997-05-29
MX9804068A (en) 1998-09-30
TR199800904T2 (en) 1998-08-21
CZ160498A3 (en) 1998-09-16
ZA969832B (en) 1997-06-17
IL124534A0 (en) 1998-12-06
JP2000500471A (en) 2000-01-18
NO982349D0 (en) 1998-05-22
PL326844A1 (en) 1998-10-26
CN1202891A (en) 1998-12-23
EP0876357A1 (en) 1998-11-11
DE19545251A1 (en) 1997-05-28
NZ330492A (en) 1999-10-28
KR19990071596A (en) 1999-09-27
HUP9902041A3 (en) 2000-07-28
WO1997019066A1 (en) 1997-05-29
HUP9902041A2 (en) 2000-04-28
AU720083B2 (en) 2000-05-25

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