EE200300346A - Androgeensed 7-asendatud 11-halogeenosteroidid - Google Patents

Androgeensed 7-asendatud 11-halogeenosteroidid

Info

Publication number: EE200300346A
Authority: EE; Estonia
Prior art keywords: halogenosteroids; androgenic; substituted
Prior art date: 2001-01-24

Application number

EEP200300346A

Other languages

English (en)

Inventor

Bohlmann Rolf

K�nzer Hermann

Nubbemeyer Reinhard

Zopf Dieter

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-24

Filing date

2002-01-24

Publication date

2003-12-15

2002-01-24 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

2003-12-15 Publication of EE200300346A publication Critical patent/EE200300346A/et

2010-02-15 Publication of EE05274B1 publication Critical patent/EE05274B1/et

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0025—Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

EEP200300346A 2001-01-24 2002-01-24 Androgeensed 7-asendatud 11-halogenosteroidid ja neid sisaldavad farmatseutilised kompositsioonid EE05274B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10104327A DE10104327A1 (de)	2001-01-24	2001-01-24	11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
PCT/EP2002/000722 WO2002059139A1 (en)	2001-01-24	2002-01-24	Androgenic 7-substituted 11-halogen steroids

Publications (2)

Publication Number	Publication Date
EE200300346A true EE200300346A (et)	2003-12-15
EE05274B1 EE05274B1 (et)	2010-02-15

Family

ID=7672351

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300346A EE05274B1 (et)	2001-01-24	2002-01-24	Androgeensed 7-asendatud 11-halogenosteroidid ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (35)

Country	Link
US (1)	US7361645B2 (et)
EP (1)	EP1353938B1 (et)
JP (1)	JP4339591B2 (et)
KR (1)	KR100728088B1 (et)
CN (1)	CN1234721C (et)
AR (1)	AR053299A1 (et)
AT (1)	ATE386045T1 (et)
AU (1)	AU2002238516B2 (et)
BG (1)	BG66133B1 (et)
BR (1)	BR0206653A (et)
CA (1)	CA2434187C (et)
CY (1)	CY1110377T1 (et)
CZ (1)	CZ303553B6 (et)
DE (2)	DE10104327A1 (et)
DK (1)	DK1353938T3 (et)
EA (1)	EA006674B1 (et)
EE (1)	EE05274B1 (et)
ES (1)	ES2300431T3 (et)
HK (1)	HK1064678A1 (et)
HR (1)	HRP20030661B1 (et)
HU (1)	HUP0303020A3 (et)
IL (2)	IL156807A0 (et)
MX (1)	MXPA03006578A (et)
NO (1)	NO325754B1 (et)
NZ (1)	NZ527041A (et)
PE (1)	PE20020848A1 (et)
PL (1)	PL207582B1 (et)
PT (1)	PT1353938E (et)
RS (1)	RS50740B (et)
SK (1)	SK287444B6 (et)
TW (1)	TWI333494B (et)
UA (1)	UA75907C2 (et)
UY (1)	UY27133A1 (et)
WO (1)	WO2002059139A1 (et)
ZA (1)	ZA200306537B (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10234525A1 (de) *	2002-07-25	2004-02-05	Schering Ag	Zusammensetzung, enthaltend ein androgenes 11ß-Halogensteroid und ein Gestagen sowie männliches Kontrazeptivum auf Basis dieser Zusammensetzung
DE10233723A1 (de)	2002-07-24	2004-02-12	Schering Ag	Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene
MXPA05001024A (es) *	2002-07-24	2005-05-16	Schering Ag	Metodo microbiologico para la produccion de 11 alfa-hdiroxiesteroides sustituidos en la posicion 7 alfa.
JP2006502997A (ja) *	2002-07-25	2006-01-26	シエーリングアクチエンゲゼルシャフト	アンドロゲン１１β‐ハロゲンステロイドおよびゲスタゲンを含有する組成物ならびにこの組成物に基づく男性用避妊薬
JO2492B1 (en) *	2003-04-28	2009-10-05	شيرينج ايه جي	A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
US7879357B2 (en) *	2003-04-28	2011-02-01	Bayer Schering Pharma Ag	Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients
CN106188202B (zh) *	2014-10-08	2017-10-24	常州大学	副产3，17‑二醇物含量大幅降低的合成睾酮方法
TWI530504B (zh) *	2014-12-01	2016-04-21	臺灣永光化學工業股份有限公司	烷基酸睾酮化合物之合成方法
US20220411460A1 (en) *	2021-06-29	2022-12-29	Board Of Regents, The University Of Texas System	Modified glucocorticoids

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB863661A (en)	1958-06-06	1961-03-22	Upjohn Co	Improvements in or relating to steroids and the manufacture thereof
CH380118A (de) *	1959-06-17	1964-07-31	Ciba Geigy	Neue Halogenandrostenverbindungen und Verfahren zu deren Herstellung
FR1489519A (fr)	1965-08-16	1967-07-21	Glaxo Lab Ltd	Procédé de préparation de nouveaux 19-nor-stéroïdes et produits obtenus
GB1159434A (en) *	1965-08-16	1969-07-23	Glaxo Lab Ltd	11beta&;-Fluoro-19-nor-Steroids
US3665021A (en)	1966-07-29	1972-05-23	Glaxo Lab Ltd	9alpha-unsubstituted-11beta-chloro-l9 nos-steroids
GB1260463A (en)	1968-01-29	1972-01-19	Glaxo Lab Ltd	11beta-BROMO-19-NOR-STEROIDS
DE2410443A1 (de) *	1974-03-01	1975-09-11	Schering Ag	11beta-fluor-androstene
DE2410442A1 (de)	1974-03-01	1975-09-11	Schering Ag	Verfahren zur herstellung von 11-fluorandrostenen
DE3214690A1 (de) *	1982-04-16	1983-10-27	Schering AG, 1000 Berlin und 4709 Bergkamen	11ss-chlor-(delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch)-steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8721384D0 (en) *	1987-09-11	1987-10-21	Erba Farmitalia	17-substituted andro-sta-1 4-dien-3-one derivatives
US5342834A (en) *	1989-04-07	1994-08-30	The Population Council, Inc.	Method for androgen supplementation
US6767902B2 (en) *	1997-09-17	2004-07-27	The Population Council, Inc.	Androgen as a male contraceptive and non-contraceptive androgen replacement
US20020012694A1 (en) *	1997-09-17	2002-01-31	Alfred J. Moo-Young	Transdermal administration of ment
US5952319A (en) *	1997-11-26	1999-09-14	Research Triangle Institute	Androgenic steroid compounds and a method of making and using the same
JP4749550B2 (ja) *	1999-03-08	2011-08-17	ナームローゼ・フエンノートチヤツプ・オルガノン	アンドロゲンとしての１４β，１７α−ヒドロキシメチルアンドロスタン誘導体
US6756366B1 (en) *	1999-04-06	2004-06-29	Akzo Nobel N.V.	Orally active androgens
DE19959696A1 (de) *	1999-12-08	2001-06-21	Jenapharm Gmbh	Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

2001
- 2001-01-24 DE DE10104327A patent/DE10104327A1/de not_active Ceased
2002
- 2002-01-24 PL PL361730A patent/PL207582B1/pl not_active IP Right Cessation
- 2002-01-24 WO PCT/EP2002/000722 patent/WO2002059139A1/en active IP Right Grant
- 2002-01-24 AU AU2002238516A patent/AU2002238516B2/en not_active Ceased
- 2002-01-24 AR ARP020100238A patent/AR053299A1/es active IP Right Grant
- 2002-01-24 EE EEP200300346A patent/EE05274B1/et not_active IP Right Cessation
- 2002-01-24 SK SK954-2003A patent/SK287444B6/sk not_active IP Right Cessation
- 2002-01-24 DK DK02704667T patent/DK1353938T3/da active
- 2002-01-24 CZ CZ20032006A patent/CZ303553B6/cs not_active IP Right Cessation
- 2002-01-24 RS YUP-594/03A patent/RS50740B/sr unknown
- 2002-01-24 HU HU0303020A patent/HUP0303020A3/hu unknown
- 2002-01-24 EA EA200300756A patent/EA006674B1/ru not_active IP Right Cessation
- 2002-01-24 DE DE60224982T patent/DE60224982T2/de not_active Expired - Lifetime
- 2002-01-24 PE PE2002000053A patent/PE20020848A1/es not_active Application Discontinuation
- 2002-01-24 UA UA2003087912A patent/UA75907C2/uk unknown
- 2002-01-24 EP EP02704667A patent/EP1353938B1/en not_active Expired - Lifetime
- 2002-01-24 BR BR0206653-0A patent/BR0206653A/pt not_active IP Right Cessation
- 2002-01-24 TW TW091101142A patent/TWI333494B/zh not_active IP Right Cessation
- 2002-01-24 MX MXPA03006578A patent/MXPA03006578A/es active IP Right Grant
- 2002-01-24 AT AT02704667T patent/ATE386045T1/de active
- 2002-01-24 KR KR1020037009732A patent/KR100728088B1/ko not_active IP Right Cessation
- 2002-01-24 PT PT02704667T patent/PT1353938E/pt unknown
- 2002-01-24 CN CNB028040686A patent/CN1234721C/zh not_active Expired - Fee Related
- 2002-01-24 JP JP2002559441A patent/JP4339591B2/ja not_active Expired - Fee Related
- 2002-01-24 US US10/467,352 patent/US7361645B2/en not_active Expired - Fee Related
- 2002-01-24 UY UY27133A patent/UY27133A1/es not_active Application Discontinuation
- 2002-01-24 ES ES02704667T patent/ES2300431T3/es not_active Expired - Lifetime
- 2002-01-24 CA CA002434187A patent/CA2434187C/en not_active Expired - Fee Related
- 2002-01-24 NZ NZ527041A patent/NZ527041A/en not_active IP Right Cessation
- 2002-01-24 IL IL15680702A patent/IL156807A0/xx active IP Right Grant
2003
- 2003-07-07 IL IL156807A patent/IL156807A/en not_active IP Right Cessation
- 2003-07-23 NO NO20033321A patent/NO325754B1/no not_active IP Right Cessation
- 2003-07-23 BG BG108023A patent/BG66133B1/bg unknown
- 2003-08-20 HR HR20030661A patent/HRP20030661B1/xx not_active IP Right Cessation
- 2003-08-21 ZA ZA200306537A patent/ZA200306537B/en unknown
2004
- 2004-09-28 HK HK04107492A patent/HK1064678A1/xx not_active IP Right Cessation
2008
- 2008-05-13 CY CY20081100508T patent/CY1110377T1/el unknown

Also Published As

Publication number	Publication date
PE20020848A1 (es)	2002-10-26
PL361730A1 (en)	2004-10-04
PT1353938E (pt)	2008-04-29
HUP0303020A2 (hu)	2003-12-29
PL207582B1 (pl)	2011-01-31
US7361645B2 (en)	2008-04-22
BR0206653A (pt)	2004-02-03
CZ20032006A3 (cs)	2004-01-14
NO20033321L (no)	2003-09-24
CA2434187A1 (en)	2002-08-01
EE05274B1 (et)	2010-02-15
TWI333494B (en)	2010-11-21
NO20033321D0 (no)	2003-07-23
CZ303553B6 (cs)	2012-12-05
DK1353938T3 (da)	2008-05-26
UY27133A1 (es)	2002-07-31
EA006674B1 (ru)	2006-02-24
KR100728088B1 (ko)	2007-06-14
EA200300756A1 (ru)	2004-02-26
RS50740B (sr)	2010-08-31
CY1110377T1 (el)	2015-04-29
BG108023A (bg)	2004-02-27
DE60224982D1 (de)	2008-03-27
IL156807A (en)	2008-08-07
JP4339591B2 (ja)	2009-10-07
NZ527041A (en)	2005-02-25
EP1353938A1 (en)	2003-10-22
MXPA03006578A (es)	2003-09-22
SK287444B6 (sk)	2010-09-07
DE10104327A1 (de)	2002-07-25
DE60224982T2 (de)	2009-04-09
BG66133B1 (bg)	2011-06-30
NO325754B1 (no)	2008-07-14
WO2002059139A1 (en)	2002-08-01
CA2434187C (en)	2009-06-16
YU59403A (sh)	2006-08-17
KR20030081391A (ko)	2003-10-17
EP1353938B1 (en)	2008-02-13
US20050075322A1 (en)	2005-04-07
AU2002238516B2 (en)	2007-08-23
CN1234721C (zh)	2006-01-04
ATE386045T1 (de)	2008-03-15
IL156807A0 (en)	2004-02-08
SK9542003A3 (en)	2003-12-02
CN1487950A (zh)	2004-04-07
HRP20030661A2 (en)	2005-06-30
HRP20030661B1 (en)	2011-10-31
JP2004517153A (ja)	2004-06-10
UA75907C2 (en)	2006-06-15
ES2300431T3 (es)	2008-06-16
ZA200306537B (en)	2004-09-08
AR053299A1 (es)	2007-05-02
HK1064678A1 (en)	2005-02-04
HUP0303020A3 (en)	2012-03-28

Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2014-10-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20140124

Publication	Publication Date	Title
ATE524462T1 (de)	2011-09-15	C5-modifizierte indazolylpyrrolotriazine
DE60214255D1 (de)	2006-10-12	Schlussstück
ATE335486T1 (de)	2006-09-15	Hydrazono-malonitrile
NO20014597D0 (no)	2001-09-21	Fremgangsmåte
DE60238924D1 (de)	2011-02-24	Abwälzfräser
ATE355059T1 (de)	2006-03-15	Isoxazolopyridinone
EE200300346A (et)	2003-12-15	Androgeensed 7-asendatud 11-halogeenosteroidid
ATE319694T1 (de)	2006-03-15	Phenylalkyne
ATA18372001A (de)	2005-07-15	Gelenksbolzenbaueinheit
ITRE20010085A0 (it)	2001-08-03	Indumento intimo
DE50212755D1 (de)	2008-10-23	Bohrfutter
ATA13992002A (de)	2003-10-15	Schlackengranulierungsanlage
ATA2892002A (de)	2005-08-15	Beschlag
NO20041687L (no)	2004-04-26	Sluttstykke
ATE345337T1 (de)	2006-12-15	Delta1 -pyrroline
AT500276B1 (de)	2006-06-15	Radschwenksystem
ATA7462001A (de)	2002-01-15	Radspannwerk
ATA15932001A (de)	2005-12-15	Leuchte
DE10196706D2 (de)	2004-07-01	Nagelfeile
ATA6162001A (de)	2002-11-15	Schneekette
DK1350054T3 (da)	2005-02-21	Aftapningsfitting
FI5213U1 (fi)	2002-01-23	Valaisin
ES1048238Y (es)	2001-12-16	Lampara
FIU20010205U0 (fi)	2001-05-21	Teline
SE0103700D0 (sv)	2001-11-07	Uppsättning