EE05530B1 - Solid compositions comprising gamma-amino acid derivatives and a process for their preparation - Google Patents

Solid compositions comprising gamma-amino acid derivatives and a process for their preparation

Info

Publication number
EE05530B1
EE05530B1 EEP200000671A EEP200000671A EE05530B1 EE 05530 B1 EE05530 B1 EE 05530B1 EE P200000671 A EEP200000671 A EE P200000671A EE P200000671 A EEP200000671 A EE P200000671A EE 05530 B1 EE05530 B1 EE 05530B1
Authority
EE
Estonia
Prior art keywords
gamma
preparation
amino acid
acid derivatives
solid compositions
Prior art date
Application number
EEP200000671A
Other languages
Estonian (et)
Inventor
Aomatsu Akira
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097314&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE05530(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Priority claimed from PCT/US1999/010186 external-priority patent/WO1999059572A1/en
Publication of EE200000671A publication Critical patent/EE200000671A/en
Publication of EE05530B1 publication Critical patent/EE05530B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone

Abstract

1. Technical Result Increase in efficiency of neuropathologic diseases treatment. 2. Essence A pharmaceutical composition containing as an active compound 4-amino-3-substituted-butanoic acid derivative of the general formula NH2 CH2 - C - CH2 COOH R1 R2 wherein the values R1 and R2, have the values indicated in the description, humectants in pharmaceutically effective amount and pharmaceutically acceptable auxiliaries. The composition is obtained by mixing the mentioned compound, humectant and pharmaceutically acceptable auxiliaries. 3. Field of Application Medicine. Tables: 10
EEP200000671A 1998-05-15 1999-05-10 Solid compositions comprising gamma-amino acid derivatives and a process for their preparation EE05530B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13312298A JP3761324B2 (en) 1998-05-15 1998-05-15 Passenger rice transplanter
PCT/US1999/010186 WO1999059572A1 (en) 1998-05-15 1999-05-10 Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same

Publications (2)

Publication Number Publication Date
EE200000671A EE200000671A (en) 2002-04-15
EE05530B1 true EE05530B1 (en) 2012-04-16

Family

ID=15097314

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000671A EE05530B1 (en) 1998-05-15 1999-05-10 Solid compositions comprising gamma-amino acid derivatives and a process for their preparation

Country Status (16)

Country Link
JP (1) JP3761324B2 (en)
CN (1) CN1171587C (en)
AT (1) ATE407668T1 (en)
CA (1) CA2325045C (en)
CY (1) CY1108488T1 (en)
DE (1) DE69939532D1 (en)
DK (1) DK1077691T3 (en)
EA (1) EA006553B1 (en)
EE (1) EE05530B1 (en)
EG (1) EG26287A (en)
ES (1) ES2312208T3 (en)
GE (1) GEP20032987B (en)
IL (2) IL139202A0 (en)
NZ (1) NZ507162A (en)
PT (1) PT1077691E (en)
UA (1) UA76398C2 (en)

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WO2013008182A1 (en) * 2011-07-10 2013-01-17 Mahesh Kandula Prodrugs of gaba analogs
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
US9399634B2 (en) 2012-05-07 2016-07-26 Cellix Bio Private Limited Compositions and methods for the treatment of depression
JP2015519333A (en) 2012-05-07 2015-07-09 セリックスビオ プライヴェート リミテッド Compositions and methods for the treatment of neurological disorders
WO2013168019A1 (en) * 2012-05-07 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of neuropathic pain
WO2013168021A1 (en) 2012-05-07 2013-11-14 Mahesh Kandula Compositions and methods for treatment of neuromuscular disorders and neurodegenerative disorders
US9309233B2 (en) 2012-05-08 2016-04-12 Cellix Bio Private Limited Compositions and methods for the treatment of blood clotting disorders
US9403826B2 (en) 2012-05-08 2016-08-02 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory disorders
WO2013167991A1 (en) 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic disorders
US9266823B2 (en) 2012-05-08 2016-02-23 Cellix Bio Private Limited Compositions and methods for the treatment of parkinson's disease
US9434704B2 (en) 2012-05-08 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of neurological degenerative disorders
US9233161B2 (en) 2012-05-10 2016-01-12 Cellix Bio Private Limited Compositions and methods for the treatment of neurological conditions
US9573927B2 (en) 2012-05-10 2017-02-21 Cellix Bio Private Limited Compositions and methods for the treatment of severe pain
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WO2013167999A2 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of neurologic diseases
US9242939B2 (en) 2012-05-10 2016-01-26 Cellix Bio Private Limited Compositions and methods for the treatment of respiratory disorders
US9499526B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurologic diseases
WO2013168016A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome
WO2013167997A2 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of metabolic syndrome
WO2013168014A1 (en) 2012-05-10 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of familial amyloid polyneuropathy
US9394288B2 (en) 2012-05-10 2016-07-19 Cellix Bio Private Limited Compositions and methods for the treatment of asthma and allergy
US20150087674A1 (en) * 2012-05-10 2015-03-26 Mahesh Kandula Compositions and methods for the treatment of severe pain
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CN104583182A (en) 2012-05-23 2015-04-29 塞利克斯比奥私人有限公司 Compositions and methods for treatment of mucositis
US9434729B2 (en) 2012-05-23 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
US9492409B2 (en) 2012-05-23 2016-11-15 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
WO2013175347A2 (en) 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of respiratory disorders
CN104603097A (en) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 Compositions and methods for the treatment of multiple sclerosis
CA2873096A1 (en) 2012-05-23 2013-11-28 Cellixbio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (en) 2012-08-03 2014-02-06 Mahesh Kandula Compositions and methods for the treatment migraine and neurologic diseases
WO2014037833A2 (en) 2012-09-06 2014-03-13 Mahesh Kandula Compositions and methods for the treatment inflammation and lipid disorders
WO2014037834A2 (en) 2012-09-08 2014-03-13 Mahesh Kandula Compositions and methods for the treatment of inflammation and lipid disorders
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
WO2014195961A1 (en) 2013-06-04 2014-12-11 Mahesh Kandula Compositions and methods for the treatment of diabetes and pre-diabetes
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
CA2976314C (en) 2014-09-26 2021-02-23 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
ES2799309T3 (en) 2014-09-29 2020-12-16 Cellix Bio Private Ltd Compounds and compositions for the treatment of multiple sclerosis
CN104352476A (en) * 2014-10-21 2015-02-18 齐宏 Gabapentin capsule and preparation method thereof
CA2965449C (en) 2014-10-27 2020-11-10 Cellix Bio Private Limited Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
US9284287B1 (en) 2014-11-05 2016-03-15 Cellix Bio Private Limited Compositions and methods for the suppression of carbonic anhydrase activity
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
US9173877B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US10208014B2 (en) 2014-11-05 2019-02-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
US9150557B1 (en) 2014-11-05 2015-10-06 Cellix Bio Private Limited Compositions and methods for the treatment of hyperglycemia
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
CN107428697A (en) 2015-01-06 2017-12-01 塞尔利克斯生物私人有限公司 For treating the composition and method of inflammation and pain

Also Published As

Publication number Publication date
PT1077691E (en) 2008-11-04
JPH11318133A (en) 1999-11-24
DK1077691T3 (en) 2008-10-27
CN1171587C (en) 2004-10-20
IL139202A (en) 2014-12-31
EA200001154A1 (en) 2001-06-25
UA76398C2 (en) 2006-08-15
IL139202A0 (en) 2001-11-25
CA2325045A1 (en) 1999-11-25
NZ507162A (en) 2003-11-28
CY1108488T1 (en) 2014-04-09
JP3761324B2 (en) 2006-03-29
CN1300213A (en) 2001-06-20
ATE407668T1 (en) 2008-09-15
GEP20032987B (en) 2003-06-25
ES2312208T3 (en) 2009-02-16
EE200000671A (en) 2002-04-15
EA006553B1 (en) 2006-02-24
EG26287A (en) 2013-06-12
CA2325045C (en) 2005-05-03
DE69939532D1 (en) 2008-10-23

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