EE04220B1 - Kontrollitud vabanemisega levosimendani peroraalsed koostised - Google Patents

Kontrollitud vabanemisega levosimendani peroraalsed koostised

Info

Publication number: EE04220B1
Authority: EE; Estonia
Prior art keywords: levosimendan; controlled release; oral formulations; release oral; formulations
Prior art date: 1998-04-23

Application number

EEP200000617A

Other languages

English (en)

Inventor

Larma Ilkka

B�ckman Maarit

Antila Saila

Lehtonen Lasse

Original Assignee

Orion Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-23

Filing date

1999-04-23

Publication date

2004-02-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8551575&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04220(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-04-23 Application filed by Orion Corporation filed Critical Orion Corporation

2002-06-17 Publication of EE200000617A publication Critical patent/EE200000617A/et

2004-02-16 Publication of EE04220B1 publication Critical patent/EE04220B1/et

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Detergent Compositions (AREA)
Cosmetics (AREA)

EEP200000617A 1998-04-23 1999-04-23 Kontrollitud vabanemisega levosimendani peroraalsed koostised EE04220B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FI980901A FI980901A (fi)	1998-04-23	1998-04-23	Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
PCT/FI1999/000329 WO1999055305A2 (en)	1998-04-23	1999-04-23	Controlled release peroral compositions of levosimendan

Publications (2)

Publication Number	Publication Date
EE200000617A EE200000617A (et)	2002-06-17
EE04220B1 true EE04220B1 (et)	2004-02-16

Family

ID=8551575

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000617A EE04220B1 (et)	1998-04-23	1999-04-23	Kontrollitud vabanemisega levosimendani peroraalsed koostised

Country Status (38)

Country	Link
US (1)	US7045147B1 (et)
EP (1)	EP1071397B1 (et)
JP (2)	JP4566402B2 (et)
KR (1)	KR100960597B1 (et)
CN (1)	CN1248691C (et)
AR (1)	AR019096A1 (et)
AT (1)	ATE258425T1 (et)
AU (1)	AU756641B2 (et)
BG (1)	BG64839B1 (et)
BR (1)	BR9909869A (et)
CA (1)	CA2329234C (et)
CO (1)	CO5070607A1 (et)
CZ (1)	CZ295194B6 (et)
DE (1)	DE69914472T2 (et)
DK (1)	DK1071397T3 (et)
EA (1)	EA002829B1 (et)
EE (1)	EE04220B1 (et)
ES (1)	ES2215379T3 (et)
FI (1)	FI980901A (et)
GE (1)	GEP20032906B (et)
HK (1)	HK1034032A1 (et)
HR (1)	HRP20000704B1 (et)
HU (1)	HUP0101458A3 (et)
ID (1)	ID27987A (et)
IL (2)	IL138951A0 (et)
MX (1)	MXPA00010367A (et)
NO (1)	NO329809B1 (et)
NZ (1)	NZ507453A (et)
PL (1)	PL197447B1 (et)
PT (1)	PT1071397E (et)
RS (1)	RS49962B (et)
SI (1)	SI1071397T1 (et)
SK (1)	SK285427B6 (et)
TR (1)	TR200003102T2 (et)
TW (1)	TWI224507B (et)
UA (1)	UA68376C2 (et)
WO (1)	WO1999055305A2 (et)
ZA (1)	ZA200005632B (et)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI20011465A0 (fi) *	2001-07-04	2001-07-04	Orion Corp	Pyridatsinonijohdannaisen uusi käyttö
JP2006520390A (ja) *	2003-03-14	2006-09-07	ムルイェ、ニルマル	徐放性錠剤の製造方法
FI20070521L (fi) *	2006-11-10	2008-05-11	Atacama Labs Oy	Rakeita, tabletteja ja rakeistusmenetelmä
BRPI0915284B1 (pt)	2008-06-30	2020-01-14	Tocagen Inc	composição farmacêutica oral, e, uso de uma composição farmacêutica
JP2014172850A (ja) *	2013-03-07	2014-09-22	Capsugel Belgium Nv	ハードカプセル製剤
CN105784895B (zh) *	2015-10-30	2018-05-22	成都欣捷高新技术开发有限公司	一种用高效液相色谱仪检测左西孟旦中杂质的方法
US11969424B2 (en)	2019-12-16	2024-04-30	Tenax Therapeutics, Inc.	Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ203684A (en)	1982-04-05	1986-06-11	Merck Sharp & Dohme	Granular formulation for the stabilization of unstable drugs or food supplements
US4716042A (en)	1986-06-16	1987-12-29	American Home Products Corporation	Stabilized coated aspirin tablets
GB8903130D0 (en) *	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones
GB2251615B (en) *	1991-01-03	1995-02-08	Orion Yhtymae Oy	(-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
US5213811A (en) *	1991-09-13	1993-05-25	Sterling Drug Inc.	Oral sustained-release drug compositions
GB2266841A (en)	1992-05-06	1993-11-17	Orion Yhtymae Oy	Compounds for use as anti-ischemic medicaments
US5795909A (en) *	1996-05-22	1998-08-18	Neuromedica, Inc.	DHA-pharmaceutical agent conjugates of taxanes
GB9614098D0 (en)	1996-07-05	1996-09-04	Orion Yhtymae Oy	Transdermal delivery of levosimendan
FI973804A (fi) *	1997-09-26	1999-03-27	Orion Yhtymae Oy	Levosimendaanin oraalisia koostumuksia
FI974578A (fi) *	1997-12-19	1999-06-20	Orion Yhtymae Oyj	Menetelmä levosimendaanin antamiseksi
FI980902A (fi) *	1998-04-23	1999-10-24	Orion Yhtymae Oyj	Levosimendaanin stabiileja koostumuksia

1998
- 1998-04-23 FI FI980901A patent/FI980901A/fi unknown
1999
- 1999-03-26 CO CO99018533A patent/CO5070607A1/es unknown
- 1999-04-09 TW TW088105661A patent/TWI224507B/zh not_active IP Right Cessation
- 1999-04-22 AR ARP990101869A patent/AR019096A1/es active IP Right Grant
- 1999-04-23 JP JP2000545505A patent/JP4566402B2/ja not_active Expired - Fee Related
- 1999-04-23 GE GEAP19995639A patent/GEP20032906B/en unknown
- 1999-04-23 TR TR2000/03102T patent/TR200003102T2/xx unknown
- 1999-04-23 EA EA200001098A patent/EA002829B1/ru not_active IP Right Cessation
- 1999-04-23 IL IL13895199A patent/IL138951A0/xx active IP Right Grant
- 1999-04-23 ES ES99916941T patent/ES2215379T3/es not_active Expired - Lifetime
- 1999-04-23 HU HU0101458A patent/HUP0101458A3/hu unknown
- 1999-04-23 AT AT99916941T patent/ATE258425T1/de not_active IP Right Cessation
- 1999-04-23 CA CA002329234A patent/CA2329234C/en not_active Expired - Fee Related
- 1999-04-23 UA UA2000116616A patent/UA68376C2/uk unknown
- 1999-04-23 DE DE69914472T patent/DE69914472T2/de not_active Expired - Lifetime
- 1999-04-23 RS YUP-639/00A patent/RS49962B/sr unknown
- 1999-04-23 AU AU35246/99A patent/AU756641B2/en not_active Ceased
- 1999-04-23 ID IDW20002367A patent/ID27987A/id unknown
- 1999-04-23 CN CNB998064181A patent/CN1248691C/zh not_active Expired - Fee Related
- 1999-04-23 WO PCT/FI1999/000329 patent/WO1999055305A2/en not_active Application Discontinuation
- 1999-04-23 NZ NZ507453A patent/NZ507453A/xx unknown
- 1999-04-23 SK SK1554-2000A patent/SK285427B6/sk not_active IP Right Cessation
- 1999-04-23 EP EP99916941A patent/EP1071397B1/en not_active Expired - Lifetime
- 1999-04-23 PT PT99916941T patent/PT1071397E/pt unknown
- 1999-04-23 SI SI9930536T patent/SI1071397T1/xx unknown
- 1999-04-23 EE EEP200000617A patent/EE04220B1/et not_active IP Right Cessation
- 1999-04-23 US US09/673,794 patent/US7045147B1/en not_active Expired - Fee Related
- 1999-04-23 DK DK99916941T patent/DK1071397T3/da active
- 1999-04-23 KR KR1020007011788A patent/KR100960597B1/ko not_active IP Right Cessation
- 1999-04-23 BR BR9909869-5A patent/BR9909869A/pt not_active Application Discontinuation
- 1999-04-23 CZ CZ20003780A patent/CZ295194B6/cs not_active IP Right Cessation
- 1999-04-23 PL PL344078A patent/PL197447B1/pl not_active IP Right Cessation
- 1999-04-23 MX MXPA00010367A patent/MXPA00010367A/es unknown
2000
- 2000-10-11 IL IL138951A patent/IL138951A/en not_active IP Right Cessation
- 2000-10-12 ZA ZA200005632A patent/ZA200005632B/en unknown
- 2000-10-19 HR HR20000704A patent/HRP20000704B1/xx not_active IP Right Cessation
- 2000-10-20 NO NO20005313A patent/NO329809B1/no not_active IP Right Cessation
- 2000-11-17 BG BG104959A patent/BG64839B1/bg unknown
2001
- 2001-02-14 HK HK01101050A patent/HK1034032A1/xx not_active IP Right Cessation
2010
- 2010-01-12 JP JP2010004367A patent/JP2010083900A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
BG104959A (en)	2001-07-31
FI980901A (fi)	1999-10-24
ID27987A (id)	2001-05-03
PL344078A1 (en)	2001-09-24
AR019096A1 (es)	2001-12-26
UA68376C2 (en)	2004-08-16
EA002829B1 (ru)	2002-10-31
DE69914472T2 (de)	2004-11-11
EA200001098A1 (ru)	2001-04-23
JP2010083900A (ja)	2010-04-15
JP4566402B2 (ja)	2010-10-20
NO329809B1 (no)	2010-12-20
SK15542000A3 (sk)	2001-08-06
MXPA00010367A (es)	2002-06-04
CO5070607A1 (es)	2001-08-28
NO20005313D0 (no)	2000-10-20
HUP0101458A3 (en)	2002-05-28
EE200000617A (et)	2002-06-17
BR9909869A (pt)	2000-12-19
IL138951A0 (en)	2001-11-25
KR20010071172A (ko)	2001-07-28
JP2002512946A (ja)	2002-05-08
CA2329234A1 (en)	1999-11-04
HRP20000704A2 (en)	2001-04-30
PT1071397E (pt)	2004-06-30
TR200003102T2 (tr)	2001-02-21
SK285427B6 (sk)	2007-01-04
YU63900A (sh)	2003-07-07
HUP0101458A2 (hu)	2002-03-28
WO1999055305A2 (en)	1999-11-04
DK1071397T3 (da)	2004-04-05
HK1034032A1 (en)	2001-10-12
KR100960597B1 (ko)	2010-06-07
GEP20032906B (en)	2003-02-25
CZ20003780A3 (en)	2001-05-16
FI980901A0 (fi)	1998-04-23
ATE258425T1 (de)	2004-02-15
RS49962B (sr)	2008-09-29
AU3524699A (en)	1999-11-16
AU756641B2 (en)	2003-01-16
WO1999055305A3 (en)	1999-12-29
CZ295194B6 (cs)	2005-06-15
CN1301163A (zh)	2001-06-27
DE69914472D1 (de)	2004-03-04
CA2329234C (en)	2008-06-10
NO20005313L (no)	2000-11-21
IL138951A (en)	2006-10-31
PL197447B1 (pl)	2008-03-31
NZ507453A (en)	2003-02-28
US7045147B1 (en)	2006-05-16
BG64839B1 (bg)	2006-06-30
EP1071397A2 (en)	2001-01-31
HRP20000704B1 (en)	2009-11-30
CN1248691C (zh)	2006-04-05
ZA200005632B (en)	2002-01-14
EP1071397B1 (en)	2004-01-28
SI1071397T1 (en)	2004-06-30
ES2215379T3 (es)	2004-10-01
TWI224507B (en)	2004-12-01

Legal Events

Date	Code	Title	Description
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2007-08-15	GB1A	Change in the ownership or in the address of the owner
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2011-12-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20110423

Publication	Publication Date	Title
IS2325B (is)	2007-12-15	Örgerðar samsetningar epleróns
DK200200116U4 (da)	2004-12-10	Mundhygiejnepræparat til behandling af halitosis
HUP0103883A3 (en)	2002-11-28	New sustained release oral formulations
DK0922386T3 (da)	2004-06-07	Sammensætninger med reguleret frigivelse
DK0973527T3 (da)	2003-11-24	Clarithromycinformuleringer med forlænget frigivelse
AR026045A1 (es)	2002-12-26	Formulaciones de liberacion prolongada de derivados de eritromocina
DK1096937T3 (da)	2005-05-09	Ranolazinformuleringer med langvarig frigivelse
DK1140105T3 (da)	2004-02-23	Galantaminpræparat med styret frigivelse
DK1067905T3 (da)	2003-02-03	Bruseformuleringer
IS5555A (is)	2000-06-30	Selekoxib lyfjablöndur
ID30031A (id)	2001-11-01	Formulasi-formulasi agrokimia
ID23546A (id)	2000-05-04	Formulasi-formulasi ziprasidon
ATE254907T1 (de)	2003-12-15	Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe
EE200000187A (et)	2001-04-16	Levosimendaani suu kaudu manustatavad segud
ATE357237T1 (de)	2007-04-15	Formulierungen enthaltend cefuroxim-axetil
DK0966299T3 (da)	2003-06-02	Hidtil ukendte orale formuleringer af calcitonin.
DE19983627T1 (de)	2001-10-18	Knoblauch-Formulierungen mit kontrollierter Freisetzung
BR9509565A (pt)	1997-09-16	Composições orais de liberação prolongada de cisaprida
HUP0204417A3 (en)	2005-03-29	Oral ciprofloxacin-composition of controlled release
EE04220B1 (et)	2004-02-16	Kontrollitud vabanemisega levosimendani peroraalsed koostised
NO20021452D0 (no)	2002-03-22	Orale kontrollerte frigivelsesformuleringer
SE9802197D0 (sv)	1998-06-18	Formulations of busulphan
SI1216032T1 (sl)	2008-06-30	Oralne formulacije s kontroliranim sproĹˇÄŤanjem
IT1305311B1 (it)	2001-05-04	Mezzi di fissaggio di protesi dentarie.