EE02938B1 - p-hüdroksübensoehappe derivaadid, nende valmistamismeetod ja kasutamine ravimitena - Google Patents

p-hüdroksübensoehappe derivaadid, nende valmistamismeetod ja kasutamine ravimitena

Info

Publication number
EE02938B1
EE02938B1 EE9400290A EE9400290A EE02938B1 EE 02938 B1 EE02938 B1 EE 02938B1 EE 9400290 A EE9400290 A EE 9400290A EE 9400290 A EE9400290 A EE 9400290A EE 02938 B1 EE02938 B1 EE 02938B1
Authority
EE
Estonia
Prior art keywords
image
preparation
acid derivatives
medicaments
hydroxybenzoic acid
Prior art date
Application number
EE9400290A
Other languages
English (en)
Inventor
Reiter Friedemann
Jank Peter
Schliack Michael
Kaipainen-Reiter Kaisli
Lang Gerhard
Schink Anne
Original Assignee
Klinge Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Pharma Gmbh filed Critical Klinge Pharma Gmbh
Publication of EE02938B1 publication Critical patent/EE02938B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04Monocyclic monocarboxylic acids
    • C07C63/06Benzoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9400290A 1990-10-09 1994-11-16 p-hüdroksübensoehappe derivaadid, nende valmistamismeetod ja kasutamine ravimitena EE02938B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4032037A DE4032037A1 (de) 1990-10-09 1990-10-09 Neue p-oxibenzoesaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
EE02938B1 true EE02938B1 (et) 1996-08-15

Family

ID=6415946

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400290A EE02938B1 (et) 1990-10-09 1994-11-16 p-hüdroksübensoehappe derivaadid, nende valmistamismeetod ja kasutamine ravimitena

Country Status (15)

Country Link
US (1) US5153353A (et)
EP (1) EP0481253B1 (et)
JP (1) JPH0791221B2 (et)
KR (1) KR950004034B1 (et)
AT (1) ATE116281T1 (et)
AU (1) AU640810B2 (et)
CA (1) CA2048355C (et)
DE (2) DE4032037A1 (et)
DK (1) DK0481253T3 (et)
EE (1) EE02938B1 (et)
ES (1) ES2066309T3 (et)
GR (1) GR3015480T3 (et)
IE (1) IE65962B1 (et)
PT (1) PT98614B (et)
ZA (1) ZA918023B (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314175C2 (de) * 1993-04-29 1995-03-30 Klinge Co Chem Pharm Fab Modifikation II von Lifibrol
DE4414537A1 (de) * 1994-04-26 1995-11-02 Klinge Co Chem Pharm Fab Kombinationspräparate mit einem Gehalt an einem p-Oxybenzoesäurederivat und einem HMG-CoA-Reduktase-Hemmer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460689C3 (de) * 1974-12-20 1980-06-26 Klinge Pharma Gmbh & Co, 8000 Muenchen 13-disubstituierte Propanol-(2)-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4144351A (en) * 1974-12-20 1979-03-13 Klinge Pharma Gmbh & Co. Substituted propanol-(2) derivatives and their preparation and use as hypolipemic drugs
DE2735856A1 (de) * 1977-08-09 1979-02-22 Klinge Co Chem Pharm Fab Neue 1,3-diphenoxypropan-2-on-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3326164A1 (de) * 1983-07-20 1985-01-31 Klinge Pharma GmbH, 8000 München Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0286703A1 (de) * 1987-04-14 1988-10-19 Klinge Pharma GmbH Neue Benzoesäure-Derivate, sowie Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
PT98614A (pt) 1992-06-30
ES2066309T3 (es) 1995-03-01
JPH04273846A (ja) 1992-09-30
DE59104058D1 (de) 1995-02-09
CA2048355C (en) 1997-11-18
PT98614B (pt) 1999-01-29
KR920007977A (ko) 1992-05-27
EP0481253B1 (de) 1994-12-28
DK0481253T3 (da) 1995-05-22
IE65962B1 (en) 1995-11-29
IE913453A1 (en) 1992-04-22
EP0481253A2 (de) 1992-04-22
CA2048355A1 (en) 1992-04-10
JPH0791221B2 (ja) 1995-10-04
DE4032037A1 (de) 1992-04-16
GR3015480T3 (en) 1995-06-30
ATE116281T1 (de) 1995-01-15
US5153353A (en) 1992-10-06
ZA918023B (en) 1992-07-29
KR950004034B1 (ko) 1995-04-22
AU8241691A (en) 1992-06-11
EP0481253A3 (en) 1992-10-21
AU640810B2 (en) 1993-09-02

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