ECSP993019A - PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE - Google Patents

PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE

Info

Publication number
ECSP993019A
ECSP993019A ECSP993019A ECSP993019A EC SP993019 A ECSP993019 A EC SP993019A EC SP993019 A ECSP993019 A EC SP993019A EC SP993019 A ECSP993019 A EC SP993019A
Authority
EC
Ecuador
Prior art keywords
diabetes
pyroleum
pirimidine
compounds
crohn
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Matthew Frank Brown
Mark Edward Flanagan
Todd Andrew Blumenkopf
Paul S Changelian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP993019 priority Critical patent/ECSP993019A/en
Publication of ECSP993019A publication Critical patent/ECSP993019A/en

Links

Abstract

La presente invención proporciona un compuesto de fórmula: (gráfico), en la que R1, R2 y R3 son como se han definido antes, que son inhibidores de las enzimas proteína tirosina quinasas, como Janus Quinasa 3 y, como tales, son una terapia útil como agentes inmunosupresores para el transplante de órganos, lupus, esclerosis múltiple, artritis reumatoide, psoriasis, diabetes Tipo I y complicaciones de la diabetes, cáncer, asma, dermatitis atópica, trastornos autoinmunes del tiroides, colitis ulcerosa, enfermedad de Crohn, enfermedad de Alzheimer, leucemia y otras enfermedades autoinmunes.The present invention provides a compound of the formula: (graph), wherein R1, R2 and R3 are as defined above, that they are inhibitors of protein tyrosine kinase enzymes, such as Janus kinase 3 and, as such, are a therapy Useful as immunosuppressive agents for organ transplantation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications of diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer, leukemia and other autoimmune diseases.

ECSP993019 1999-06-16 1999-06-16 PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE ECSP993019A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP993019 ECSP993019A (en) 1999-06-16 1999-06-16 PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP993019 ECSP993019A (en) 1999-06-16 1999-06-16 PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE

Publications (1)

Publication Number Publication Date
ECSP993019A true ECSP993019A (en) 1999-08-12

Family

ID=42044008

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP993019 ECSP993019A (en) 1999-06-16 1999-06-16 PYROLEUM COMPOUNDS [2,3-d] PIRIMIDINE

Country Status (1)

Country Link
EC (1) ECSP993019A (en)

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