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Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Se describen compuestos de fórmula (gráfico), los cuales tienen actividad como inhibidores de la unión entre la VCAM-1 y las células que expresan la VLA-4. Dichos compuestos son de utilidad para el tratamiento de enfermedades cuyos sintomas y/o lesiones están relacionadas con la unión de la VCAM-1 a las células que expresan la VLA-4.Compounds of the formula (graph) are described, which have activity as inhibitors of the binding between VCAM-1 and cells expressing VLA-4. Said compounds are useful for the treatment of diseases whose symptoms and / or lesions are related to the binding of VCAM-1 to cells that express VLA-4.
ECSP9826341998-08-211998-08-21
DERIVATIVES OF N- AROYLOPHENYL ALANINE
ECSP982634A
(en)
3-SUBSTITUTED PIRROLIDINS USED AS INHIBITORS OF THE METALOPROTEINAS OF THE MATRIX, PHARMACEUTICAL COMPOSITION AND USES FOR THE MANUFACTURE OF PHARMACEUTICAL DECOMPOSITIONS FOR TREATMENT OF DISEASES.