ECSP034570A - FORMULATION OF AN INHALATION SOLUTION WITH A TIOTROPIO SALT - Google Patents
FORMULATION OF AN INHALATION SOLUTION WITH A TIOTROPIO SALTInfo
- Publication number
- ECSP034570A ECSP034570A EC2003004570A ECSP034570A ECSP034570A EC SP034570 A ECSP034570 A EC SP034570A EC 2003004570 A EC2003004570 A EC 2003004570A EC SP034570 A ECSP034570 A EC SP034570A EC SP034570 A ECSP034570 A EC SP034570A
- Authority
- EC
- Ecuador
- Prior art keywords
- formulation
- tiotropio
- salt
- inhalation solution
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Abstract
La presente invención se refiere a una formulación para inhalación exenta de gases propelentes de bromuro de tiotropio o monohidrato de bromuro de tiotropio, disuelto en agua o en una mezcla de agua y etanol, así como a los aerosoles inhalables exentos de gases propelentes resultantes de ella.The present invention relates to a formulation for inhalation free of propellant gases of tiotropium bromide or tiotropium bromide monohydrate, dissolved in water or in a mixture of water and ethanol, as well as inhalable aerosols free of propellant gases resulting therefrom. .
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10054042 | 2000-10-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP034570A true ECSP034570A (en) | 2003-06-25 |
Family
ID=7661727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2003004570A ECSP034570A (en) | 2000-10-31 | 2003-04-28 | FORMULATION OF AN INHALATION SOLUTION WITH A TIOTROPIO SALT |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1335729A2 (en) |
JP (1) | JP4559703B2 (en) |
KR (1) | KR100983208B1 (en) |
CN (1) | CN1237970C (en) |
AR (1) | AR038765A1 (en) |
AU (2) | AU2002221741B2 (en) |
BG (1) | BG66425B1 (en) |
BR (1) | BR0115016A (en) |
CA (1) | CA2427583C (en) |
CZ (1) | CZ305033B6 (en) |
DE (1) | DE10152369A1 (en) |
EA (1) | EA009068B1 (en) |
EC (1) | ECSP034570A (en) |
EE (1) | EE05343B1 (en) |
HK (1) | HK1060569A1 (en) |
HR (1) | HRP20030337A2 (en) |
HU (1) | HUP0301377A3 (en) |
IL (2) | IL155676A0 (en) |
ME (1) | ME00242B (en) |
MX (1) | MXPA03003750A (en) |
MY (1) | MY132777A (en) |
NO (1) | NO332524B1 (en) |
NZ (1) | NZ526024A (en) |
PE (1) | PE20020518A1 (en) |
PL (1) | PL361001A1 (en) |
SA (1) | SA01220503B1 (en) |
SK (1) | SK288031B6 (en) |
TW (1) | TWI296934B (en) |
UA (1) | UA76435C2 (en) |
UY (1) | UY26991A1 (en) |
WO (1) | WO2002036591A2 (en) |
YU (1) | YU33103A (en) |
ZA (1) | ZA200303045B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL151960A0 (en) | 2000-04-28 | 2003-04-10 | Kosan Biosciences Inc | Production of polyketides |
US20030235538A1 (en) | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
AU2004279438A1 (en) * | 2003-10-09 | 2005-04-21 | Inverseon, Inc. | Methods for treating diseases and conditions with inverse agonists |
SE0303269L (en) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medical product |
SI1863476T1 (en) * | 2005-03-16 | 2016-05-31 | Meda Pharma Gmbh & Co. Kg | The combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases |
CA2653744C (en) * | 2006-05-26 | 2018-01-16 | Dey, L.P. | Nebulizable compositions of quaternary ammonium muscarinic receptor antagonists |
CN100446770C (en) * | 2007-01-10 | 2008-12-31 | 上海现代药物制剂工程研究中心有限公司 | Water aerosol containing beclomethasone dipropionate |
TR200907237A2 (en) * | 2009-09-23 | 2011-04-21 | Bi̇lgi̇ç Mahmut | Tiotropium dry powder combination |
CN116173025A (en) * | 2018-07-26 | 2023-05-30 | 四川海思科制药有限公司 | Aerosol pharmaceutical composition containing glycopyrronium salt and indacaterol salt, and preparation method and application thereof |
CN111971034A (en) * | 2018-07-26 | 2020-11-20 | 四川海思科制药有限公司 | Aerosol pharmaceutical composition containing glycopyrronium salt and preparation method and application thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0504112A3 (en) * | 1991-03-14 | 1993-04-21 | Ciba-Geigy Ag | Pharmaceutical aerosol formulations |
DE4203306A1 (en) * | 1992-02-06 | 1993-08-12 | Ig Spruehtechnik Gmbh | ASTHMA OR PULMONAL AEROSOL PREPARATIONS WITH LECITHIN |
BR9609307B1 (en) * | 1995-06-27 | 2010-03-09 | pharmaceutical preparation for the production of lung-propellant-free inhaled aerosols as well as aerosol comprising the same. | |
US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
BR9709650A (en) * | 1996-06-04 | 1999-08-10 | Procter & Gamble | Nasal aerosol containing an intransal steroid and an antihistamine |
DE19653969A1 (en) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | New aqueous pharmaceutical preparation for the production of propellant-free aerosols |
JPH10298107A (en) * | 1997-04-25 | 1998-11-10 | Taisho Pharmaceut Co Ltd | Pharmaceutical composition |
CN1150890C (en) * | 1998-08-04 | 2004-05-26 | 杰格研究股份公司 | Medicinal aerosol formulations |
DE19847968A1 (en) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Separate storage of an active material and a solvent comprises a closure cap and a container, with a chamber attached to the unit. |
-
2001
- 2001-10-24 CA CA002427583A patent/CA2427583C/en not_active Expired - Fee Related
- 2001-10-24 IL IL15567601A patent/IL155676A0/en unknown
- 2001-10-24 CZ CZ2003-1487A patent/CZ305033B6/en not_active IP Right Cessation
- 2001-10-24 AU AU2002221741A patent/AU2002221741B2/en not_active Expired
- 2001-10-24 SK SK526-2003A patent/SK288031B6/en not_active IP Right Cessation
- 2001-10-24 KR KR1020037006001A patent/KR100983208B1/en active IP Right Grant
- 2001-10-24 EA EA200300483A patent/EA009068B1/en not_active IP Right Cessation
- 2001-10-24 NZ NZ526024A patent/NZ526024A/en not_active IP Right Cessation
- 2001-10-24 DE DE10152369A patent/DE10152369A1/en not_active Withdrawn
- 2001-10-24 JP JP2002539350A patent/JP4559703B2/en not_active Expired - Lifetime
- 2001-10-24 BR BR0115016-2A patent/BR0115016A/en active Pending
- 2001-10-24 WO PCT/EP2001/012296 patent/WO2002036591A2/en active IP Right Grant
- 2001-10-24 EP EP01992710A patent/EP1335729A2/en not_active Ceased
- 2001-10-24 EE EEP200300202A patent/EE05343B1/en unknown
- 2001-10-24 HU HU0301377A patent/HUP0301377A3/en unknown
- 2001-10-24 PL PL01361001A patent/PL361001A1/en not_active Application Discontinuation
- 2001-10-24 UA UA2003054960A patent/UA76435C2/en unknown
- 2001-10-24 MX MXPA03003750A patent/MXPA03003750A/en active IP Right Grant
- 2001-10-24 CN CNB018183271A patent/CN1237970C/en not_active Expired - Lifetime
- 2001-10-24 AU AU2174102A patent/AU2174102A/en active Pending
- 2001-10-24 YU YU33103A patent/YU33103A/en unknown
- 2001-10-24 ME MEP-2008-407A patent/ME00242B/en unknown
- 2001-10-29 UY UY26991A patent/UY26991A1/en not_active Application Discontinuation
- 2001-10-29 PE PE2001001072A patent/PE20020518A1/en active IP Right Grant
- 2001-10-29 TW TW090126752A patent/TWI296934B/en not_active IP Right Cessation
- 2001-10-29 MY MYPI20014987A patent/MY132777A/en unknown
- 2001-10-31 AR ARP010105088A patent/AR038765A1/en not_active Ceased/Invalidation/Refusal/Rejection/Nullification
- 2001-11-03 SA SA01220503A patent/SA01220503B1/en unknown
-
2003
- 2003-04-16 BG BG107726A patent/BG66425B1/en active Active
- 2003-04-17 ZA ZA200303045A patent/ZA200303045B/en unknown
- 2003-04-28 HR HR20030337A patent/HRP20030337A2/en not_active Application Discontinuation
- 2003-04-28 EC EC2003004570A patent/ECSP034570A/en unknown
- 2003-04-29 NO NO20031914A patent/NO332524B1/en not_active IP Right Cessation
- 2003-04-30 IL IL155676A patent/IL155676A/en active IP Right Grant
-
2004
- 2004-05-20 HK HK04103587A patent/HK1060569A1/en not_active IP Right Cessation
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