ECSP003672A - SECRETASE IN THE DISEASE OF ALZHEIMER, SUBSTRATES OF THE APP AND ITS USES - Google Patents
SECRETASE IN THE DISEASE OF ALZHEIMER, SUBSTRATES OF THE APP AND ITS USESInfo
- Publication number
- ECSP003672A ECSP003672A ECSP003672A ECSP003672A EC SP003672 A ECSP003672 A EC SP003672A EC SP003672 A ECSP003672 A EC SP003672A EC SP003672 A ECSP003672 A EC SP003672A
- Authority
- EC
- Ecuador
- Prior art keywords
- app
- secretase
- alzheimer
- disease
- substrates
- Prior art date
Links
Landscapes
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención proporciona la enzima y los procedimientos enzimáticos para escindir el sitio de escición de a-secretasa de la proteína APP, y los correspondientes ácidos nucleicos, péptidos, vectores, células y aislados celulares y ensayos. También se proporciona una enzima que corta el sitio a-secretasa de APP. La invención además proporciona una proteína APP modificada y sus correspondientes ácidos nucleicos, péptidos, vectores, células y aislados celulares, y ensayos que son esencialmente útiles para identificar sustancias potencialmente terapéuticas en el tratamiento o la prevención de la enfermedad de Alzheimer.The present invention provides the enzyme and enzymatic methods for cleaving the a-secretase cleavage site of the APP protein, and the corresponding nucleic acids, peptides, vectors, cells and cell isolates and assays. An enzyme that cuts the APP-secretase site of APP is also provided. The invention further provides a modified APP protein and its corresponding nucleic acids, peptides, vectors, cells and cell isolates, and assays that are essentially useful for identifying potentially therapeutic substances in the treatment or prevention of Alzheimer's disease.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP003672 ECSP003672A (en) | 2000-09-22 | 2000-09-22 | SECRETASE IN THE DISEASE OF ALZHEIMER, SUBSTRATES OF THE APP AND ITS USES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP003672 ECSP003672A (en) | 2000-09-22 | 2000-09-22 | SECRETASE IN THE DISEASE OF ALZHEIMER, SUBSTRATES OF THE APP AND ITS USES |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP003672A true ECSP003672A (en) | 2001-04-23 |
Family
ID=42041266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSP003672 ECSP003672A (en) | 2000-09-22 | 2000-09-22 | SECRETASE IN THE DISEASE OF ALZHEIMER, SUBSTRATES OF THE APP AND ITS USES |
Country Status (1)
Country | Link |
---|---|
EC (1) | ECSP003672A (en) |
-
2000
- 2000-09-22 EC ECSP003672 patent/ECSP003672A/en unknown
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