EA202192044A2 - METHODS AND DEVICES FOR NONDESTROUSING DETECTION OF UNSOLVED PARTICLES IN A FLUID MEDIUM - Google Patents

METHODS AND DEVICES FOR NONDESTROUSING DETECTION OF UNSOLVED PARTICLES IN A FLUID MEDIUM

Info

Publication number
EA202192044A2
EA202192044A2 EA202192044A EA202192044A EA202192044A2 EA 202192044 A2 EA202192044 A2 EA 202192044A2 EA 202192044 A EA202192044 A EA 202192044A EA 202192044 A EA202192044 A EA 202192044A EA 202192044 A2 EA202192044 A2 EA 202192044A2
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
nondestrousing
detection
devices
fluid medium
Prior art date
Application number
EA202192044A
Other languages
Russian (ru)
Other versions
EA202192044A3 (en
Inventor
Грэхам Ф. Милн
Эрвин Фройнд
Райан Л. Смит
Original Assignee
Амген Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Амген Инк. filed Critical Амген Инк.
Publication of EA202192044A2 publication Critical patent/EA202192044A2/en
Publication of EA202192044A3 publication Critical patent/EA202192044A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9036—Investigating the presence of flaws or contamination in a container or its contents using arrays of emitters or receivers
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Dispersion Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Установки, способы и компьютерные программные продукты, раскрытые в настоящем описании, могут быть использованы для неразрушающего обнаружения нерастворенных частей, таких как осколки стекла и/или белковые агрегаты, в текучей среде, находящейся в сосуде, такой как, без ограничения, жидкость, содержащая лекарственное средство.The apparatus, methods, and computer program products disclosed herein can be used to non-destructively detect undissolved parts such as glass shards and / or protein aggregates in a fluid within a vessel, such as, without limitation, a liquid containing a drug. means.

EA202192044A 2012-08-20 2012-08-29 METHODS AND DEVICES FOR NON-DESTRUCTIVE DETECTION OF UNDISOLUTE PARTICLES IN FLUID EA202192044A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261691211P 2012-08-20 2012-08-20

Publications (2)

Publication Number Publication Date
EA202192044A2 true EA202192044A2 (en) 2021-11-30
EA202192044A3 EA202192044A3 (en) 2022-03-31

Family

ID=71138801

Family Applications (2)

Application Number Title Priority Date Filing Date
EA202192044A EA202192044A3 (en) 2012-08-20 2012-08-29 METHODS AND DEVICES FOR NON-DESTRUCTIVE DETECTION OF UNDISOLUTE PARTICLES IN FLUID
EA201992857A EA038813B1 (en) 2012-08-20 2012-08-29 Methods and apparatus for nondestructive detection of undissolved particles in a fluid

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201992857A EA038813B1 (en) 2012-08-20 2012-08-29 Methods and apparatus for nondestructive detection of undissolved particles in a fluid

Country Status (1)

Country Link
EA (2) EA202192044A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117242336A (en) * 2021-04-28 2023-12-15 斯特瓦纳托集团有限公司 Device and method for inspecting a container at least partially transparent to predetermined electromagnetic radiation
WO2024052440A1 (en) * 2022-09-09 2024-03-14 F. Hoffmann-La Roche Ag Inspection system and method for a closed medical container

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02159539A (en) * 1988-12-14 1990-06-19 Toshiba Corp Floc image camera apparatus for water purifying plant
US5905568A (en) * 1997-12-15 1999-05-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Stereo imaging velocimetry
JP2002267612A (en) * 2001-03-13 2002-09-18 Hitachi Eng Co Ltd Device and system for inspecting foreign matter in liquid filled in transparent container or the like
JP4152650B2 (en) * 2002-03-18 2008-09-17 セファテクノロジー株式会社 Apparatus and method for measuring sedimentation rate of liquid sample
JP4048848B2 (en) * 2002-06-28 2008-02-20 株式会社日立プラントテクノロジー Foreign object detection device in container and foreign object detection method in container
WO2006011803A2 (en) * 2004-07-30 2006-02-02 Eagle Vision Systems B.V. Apparatus and method for checking of containers

Also Published As

Publication number Publication date
EA202192044A3 (en) 2022-03-31
EA201992857A1 (en) 2020-06-30
EA038813B1 (en) 2021-10-22

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