EA202191161A1 - A NEW METHOD FOR OBTAINING (S) -2- (2- (4-HYDROXYPHENYL) ACETAMIDO) -3-PHENYLPROPANIC ACID - Google Patents

A NEW METHOD FOR OBTAINING (S) -2- (2- (4-HYDROXYPHENYL) ACETAMIDO) -3-PHENYLPROPANIC ACID

Info

Publication number
EA202191161A1
EA202191161A1 EA202191161A EA202191161A EA202191161A1 EA 202191161 A1 EA202191161 A1 EA 202191161A1 EA 202191161 A EA202191161 A EA 202191161A EA 202191161 A EA202191161 A EA 202191161A EA 202191161 A1 EA202191161 A1 EA 202191161A1
Authority
EA
Eurasian Patent Office
Prior art keywords
acetamido
hydroxyphenyl
obtaining
new method
phenylpropanic acid
Prior art date
Application number
EA202191161A
Other languages
Russian (ru)
Inventor
Владимир Евгеньевич НЕБОЛЬСИН
Татьяна Александровна КРОМОВА
Original Assignee
Общество С Ограниченной Ответственностью "Фарминтерпрайсез"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Общество С Ограниченной Ответственностью "Фарминтерпрайсез" filed Critical Общество С Ограниченной Ответственностью "Фарминтерпрайсез"
Publication of EA202191161A1 publication Critical patent/EA202191161A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Abstract

Настоящее изобретение относится к химии органических соединений, фармакологии и медицине и касается способа получения (S)-2-(2-(4-гидроксифенил)ацетамидо)-3-фенилпропановой кислоты чистотой выше 99,0% и не содержащей единичной примеси выше 0,1%, пригодной для использования в качестве фармацевтической субстанции в производстве различных видов лекарственных форм.The present invention relates to the chemistry of organic compounds, pharmacology and medicine and relates to a method for producing (S) -2- (2- (4-hydroxyphenyl) acetamido) -3-phenylpropanoic acid with a purity higher than 99.0% and not containing a single impurity higher than 0, 1%, suitable for use as a pharmaceutical substance in the production of various types of dosage forms.

EA202191161A 2018-10-29 2019-10-25 A NEW METHOD FOR OBTAINING (S) -2- (2- (4-HYDROXYPHENYL) ACETAMIDO) -3-PHENYLPROPANIC ACID EA202191161A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2018138021A RU2727703C2 (en) 2018-10-29 2018-10-29 Novel method of producing (s)-2-(2-(4-hydroxyphenyl)acetamido)-3-phenylpropanoic acid
PCT/RU2019/050200 WO2020091633A1 (en) 2018-10-29 2019-10-25 Novel method for producing (s)-2-(2-(4-hydroxyphenyl)acetamido)-3-phenylpropanoic acid

Publications (1)

Publication Number Publication Date
EA202191161A1 true EA202191161A1 (en) 2021-07-26

Family

ID=70462694

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202191161A EA202191161A1 (en) 2018-10-29 2019-10-25 A NEW METHOD FOR OBTAINING (S) -2- (2- (4-HYDROXYPHENYL) ACETAMIDO) -3-PHENYLPROPANIC ACID

Country Status (3)

Country Link
EA (1) EA202191161A1 (en)
RU (1) RU2727703C2 (en)
WO (1) WO2020091633A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2309144C2 (en) * 2005-03-25 2007-10-27 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Phenyl-containing n-acylamine derivatives, method for production thereof, pharmaceutical composition and uses thereof as anti-inflammatory and analgesic agents

Also Published As

Publication number Publication date
RU2727703C2 (en) 2020-07-23
RU2018138021A (en) 2020-04-29
RU2018138021A3 (en) 2020-04-29
WO2020091633A1 (en) 2020-05-07

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