EA202092602A2 - -D-2'-DESOXY-2 '- FLUORINE-2' - C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HCV-INDUCED DISEASES - Google Patents

-D-2'-DESOXY-2 '- FLUORINE-2' - C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HCV-INDUCED DISEASES

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Publication number
EA202092602A2
EA202092602A2 EA202092602A EA202092602A EA202092602A2 EA 202092602 A2 EA202092602 A2 EA 202092602A2 EA 202092602 A EA202092602 A EA 202092602A EA 202092602 A EA202092602 A EA 202092602A EA 202092602 A2 EA202092602 A2 EA 202092602A2
Authority
EA
Eurasian Patent Office
Prior art keywords
substituted
treatment
hcv
desoxy
fluorine
Prior art date
Application number
EA202092602A
Other languages
Russian (ru)
Other versions
EA202092602A3 (en
Inventor
Жан-Пьер Соммадосси
Адель Мусса
Original Assignee
Атеа Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Атеа Фармасьютикалс, Инк. filed Critical Атеа Фармасьютикалс, Инк.
Publication of EA202092602A2 publication Critical patent/EA202092602A2/en
Publication of EA202092602A3 publication Critical patent/EA202092602A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Соединение структурыили его фармацевтически приемлемая соль или композиция для лечения хозяина, инфицированного или подвергнутого воздействию вируса HCV или другим нарушениям, которые более подробно описаны в настоящем изобретении.A compound of structure or a pharmaceutically acceptable salt or composition thereof for the treatment of a host infected with or exposed to HCV virus or other disorders, which are described in more detail in the present invention.

EA202092602A 2016-01-08 2016-03-07 Β-D-2'-DEOXY-2'-Α-FLUORINE-2'-Β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HCV-INDUCED DISEASES EA202092602A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662276597P 2016-01-08 2016-01-08

Publications (2)

Publication Number Publication Date
EA202092602A2 true EA202092602A2 (en) 2021-06-30
EA202092602A3 EA202092602A3 (en) 2021-09-30

Family

ID=76807394

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092602A EA202092602A3 (en) 2016-01-08 2016-03-07 Β-D-2'-DEOXY-2'-Α-FLUORINE-2'-Β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HCV-INDUCED DISEASES

Country Status (1)

Country Link
EA (1) EA202092602A3 (en)

Also Published As

Publication number Publication date
EA202092602A3 (en) 2021-09-30

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